Inhibition of TMEM16A improves cisplatin-induced acute kidney injury via preventing DRP1-mediated mitochondrial fission.

[1]  Shanping He,et al.  Honokiol ameliorates cisplatin‐induced acute kidney injury via inhibition of mitochondrial fission , 2022, British journal of pharmacology.

[2]  Y. Guan,et al.  Blockade of TMEM16A protects against renal fibrosis by reducing intracellular Cl− concentration , 2021, British journal of pharmacology.

[3]  N. Chattipakorn,et al.  Mitochondrial dynamics and diabetic kidney disease: Missing pieces for the puzzle of therapeutic approaches , 2021, Journal of cellular and molecular medicine.

[4]  Lu Tie,et al.  Emodin prevents renal ischemia-reperfusion injury via suppression of CAMKII/DRP1-mediated mitochondrial fission. , 2021, European journal of pharmacology.

[5]  Y. Guan,et al.  TMEM16A inhibits angiotensin II-induced basilar artery smooth muscle cell migration in a WNK1-dependent manner , 2021, Acta Pharmaceutica Sinica. B.

[6]  Xiuling Zhi,et al.  Drp1-dependent mitochondrial fission in cardiovascular disease , 2020, Acta Pharmacologica Sinica.

[7]  Liming Chen,et al.  Empagliflozin alleviated mitochondrial fission via decreasing PGAM5. , 2020, Metabolism: clinical and experimental.

[8]  J. Holien,et al.  New perspectives on the role of Drp1 isoforms in regulating mitochondrial pathophysiology. , 2020, Pharmacology & therapeutics.

[9]  Zhanjun Jia,et al.  Nuclear receptor PXR targets AKR1B7 to protect mitochondrial metabolism and renal function in AKI , 2020, Science Translational Medicine.

[10]  Lingling Zhu,et al.  Activation of TFEB-mediated autophagy by trehalose attenuates mitochondrial dysfunction in cisplatin-induced acute kidney injury , 2020, Theranostics.

[11]  Jun Ren,et al.  Fundc1-dependent mitophagy is obligatory to ischemic preconditioning-conferred renoprotection in ischemic AKI via suppression of Drp1-mediated mitochondrial fission , 2019, Redox biology.

[12]  M. Aschner,et al.  Dysregulation of TFEB contributes to Manganese-induced Autophagic Failure and Mitochondrial Dysfunction in Astrocytes. , 2019, Autophagy.

[13]  C. Guda,et al.  Proximal tubule cyclophilin D regulates fatty acid oxidation in cisplatin-induced acute kidney injury. , 2019, Kidney international.

[14]  Jing Nie,et al.  Numb Depletion Promotes Drp1-Mediated Mitochondrial Fission and Exacerbates Mitochondrial Fragmentation and Dysfunction in Acute Kidney Injury. , 2019, Antioxidants & redox signaling.

[15]  B. Zhang,et al.  Renalase attenuates mitochondrial fission in cisplatin‐induced acute kidney injury via modulating sirtuin‐3 , 2019, Life sciences.

[16]  Lijun Xu,et al.  Berberine Protects Glomerular Podocytes via Inhibiting Drp1-Mediated Mitochondrial Fission and Dysfunction , 2019, Theranostics.

[17]  Hailong An,et al.  Recent advances in TMEM16A: Structure, function, and disease , 2018, Journal of cellular physiology.

[18]  Jianjun Gao,et al.  Inhibition of ANO1/TMEM16A induces apoptosis in human prostate carcinoma cells by activating TNF-α signaling , 2018, Cell Death & Disease.

[19]  J. Pei,et al.  Melatonin prevents Drp1‐mediated mitochondrial fission in diabetic hearts through SIRT1‐PGC1α pathway , 2018, Journal of pineal research.

[20]  J. Forbes,et al.  Mitochondrial dysfunction in diabetic kidney disease , 2018, Nature Reviews Nephrology.

[21]  M. Wei,et al.  Cell-specific mechanisms of TMEM16A Ca2+-activated chloride channel in cancer , 2017, Molecular Cancer.

[22]  P. Bhargava,et al.  Mitochondrial energetics in the kidney , 2017, Nature Reviews Nephrology.

[23]  F. Emma,et al.  Mitochondrial dysfunction in inherited renal disease and acute kidney injury , 2016, Nature Reviews Nephrology.

[24]  J. Ousingsawat,et al.  Modulating Ca2+ signals: a common theme for TMEM16, Ist2, and TMC , 2016, Pflügers Archiv - European Journal of Physiology.

[25]  D. Bonenfant,et al.  ANO1/TMEM16A interacts with EGFR and correlates with sensitivity to EGFR-targeting therapy in head and neck cancer , 2015, Oncotarget.

[26]  R. Witzgall,et al.  The calcium-activated chloride channel Anoctamin 1 contributes to the regulation of renal function. , 2014, Kidney international.

[27]  G. Schley,et al.  Anoctamin 1 induces calcium-activated chloride secretion and proliferation of renal cyst-forming epithelial cells. , 2014, Kidney international.

[28]  I. Clay,et al.  Calcium-activated chloride channel ANO1 promotes breast cancer progression by activating EGFR and CAMK signaling , 2013, Proceedings of the National Academy of Sciences.

[29]  Min Ho Tak,et al.  TMEM16A confers receptor-activated calcium-dependent chloride conductance , 2008, Nature.

[30]  Roberto Ravazzolo,et al.  TMEM16A, A Membrane Protein Associated with Calcium-Dependent Chloride Channel Activity , 2008, Science.