A weighted and integrated drug-target interactome: drug repurposing for schizophrenia as a use case
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Ergin Soysal | Hua Xu | W. Jim Zheng | Zhongming Zhao | Jingchun Sun | Liang-Chin Huang | Zhongming Zhao | Hua Xu | Jingchun Sun | Liang-Chin Huang | E. Soysal | W. J. Zheng | H. Xu | Hua Xu | Hua Xu
[1] Mathias Dunkel,et al. SuperPred: update on drug classification and target prediction , 2014, Nucleic Acids Res..
[2] W. Fleischhacker,et al. Sibutramine in the treatment of antipsychotic-induced weight gain: a pilot study in patients with schizophrenia , 2014, International clinical psychopharmacology.
[3] S. Moritz,et al. Effects of dopaminergic modulation on automatic semantic priming: a double-blind study. , 2014, Journal of psychiatry & neuroscience : JPN.
[4] N. Gençer,et al. Antipsychotic agents screened as human carbonic anhydrase I and II inhibitors , 2014, Archives of physiology and biochemistry.
[5] Damian Szklarczyk,et al. STITCH 4: integration of protein–chemical interactions with user data , 2013, Nucleic Acids Res..
[6] María Martín,et al. Activities at the Universal Protein Resource (UniProt) , 2013, Nucleic Acids Res..
[7] David S. Wishart,et al. DrugBank 4.0: shedding new light on drug metabolism , 2013, Nucleic Acids Res..
[8] Yanli Wang,et al. PubChem BioAssay: 2014 update , 2013, Nucleic Acids Res..
[9] A. Butte,et al. A drug repositioning approach identifies tricyclic antidepressants as inhibitors of small cell lung cancer and other neuroendocrine tumors. , 2013, Cancer discovery.
[10] Abdelaziz Ghanemi. Schizophrenia and Parkinson’s disease: Selected therapeutic advances beyond the dopaminergic etiologies , 2013 .
[11] Thomas C. Wiegers,et al. A CTD–Pfizer collaboration: manual curation of 88 000 scientific articles text mined for drug–disease and drug–phenotype interactions , 2013, Database J. Biol. Databases Curation.
[12] Joshua F. McMichael,et al. DGIdb - Mining the druggable genome , 2013, Nature Methods.
[13] Zhongming Zhao,et al. Characterization of Schizophrenia Adverse Drug Interactions through a Network Approach and Drug Classification , 2013, BioMed research international.
[14] Tudor I. Oprea,et al. The CARLSBAD Database: A Confederated Database of Chemical Bioactivities , 2013, Database J. Biol. Databases Curation.
[15] Nancy Légaré,et al. Increasing the clozapine: norclozapine ratio with co-administration of fluvoxamine to enhance efficacy and minimize side effects of clozapine therapy. , 2013, Medical hypotheses.
[16] P. Sanseau,et al. Computational Drug Repositioning: From Data to Therapeutics , 2013, Clinical pharmacology and therapeutics.
[17] Anushya Muruganujan,et al. PANTHER in 2013: modeling the evolution of gene function, and other gene attributes, in the context of phylogenetic trees , 2012, Nucleic Acids Res..
[18] Wigard Me,et al. [Addition of fluvoxamine to clozapine: theory and practice]. , 2013 .
[19] A. V. Van Gool,et al. [Addition of fluvoxamine to clozapine: theory and practice]. , 2013, Tijdschrift voor psychiatrie.
[20] C. Fuchs,et al. Reducing antipsychotic-induced weight gain in schizophrenia: a double-blind placebo-controlled study of reboxetine–betahistine combination , 2012, Psychopharmacology.
[21] N. Kanahara,et al. A Randomized, Double-Blind, Placebo-Controlled Trial of Fluvoxamine in Patients With Schizophrenia: A Preliminary Study , 2012, Journal of clinical psychopharmacology.
[22] R. Altman,et al. Pharmacogenomics Knowledge for Personalized Medicine , 2012, Clinical pharmacology and therapeutics.
[23] P. Bork,et al. Drug discovery in the age of systems biology: the rise of computational approaches for data integration. , 2012, Current opinion in biotechnology.
[24] Hua Xu,et al. DTome: a web-based tool for drug-target interactome construction , 2012, BMC Bioinformatics.
[25] L. Cardon,et al. Use of genome-wide association studies for drug repositioning , 2012, Nature Biotechnology.
[26] Jianmin Wu,et al. PINA v2.0: mining interactome modules , 2011, Nucleic Acids Res..
[27] Yang Song,et al. Therapeutic target database update 2012: a resource for facilitating target-oriented drug discovery , 2011, Nucleic Acids Res..
[28] John P. Overington,et al. ChEMBL: a large-scale bioactivity database for drug discovery , 2011, Nucleic Acids Res..
[29] Pankaj Agarwal,et al. Systematic Drug Repositioning Based on Clinical Side-Effects , 2011, PloS one.
[30] Xiaohua Douglas Zhang. Optimal High-Throughput Screening: Practical Experimental Design and Data Analysis for Genome-Scale RNAi Research , 2011 .
[31] Philip E. Bourne,et al. PROMISCUOUS: a database for network-based drug-repositioning , 2010, Nucleic Acids Res..
[32] Xiaohua Douglas Zhang. Optimal High-Throughput Screening: Optimal High-Throughput Screening , 2011 .
[33] A. Meyer-Lindenberg,et al. Polypharmacy in schizophrenia , 2010, Current opinion in psychiatry.
[34] Michael Schroeder,et al. SuperCYP: a comprehensive database on Cytochrome P450 enzymes including a tool for analysis of CYP-drug interactions , 2009, Nucleic Acids Res..
[35] 陳俊興,et al. Treatment Strategy for Refractory Schizophrenia: Drug Interaction between Clozapine and Fluvoxamine , 2010 .
[36] R. Iyengar,et al. Systems pharmacology. , 2010, The Mount Sinai journal of medicine, New York.
[37] Peilin Jia,et al. A multi-dimensional evidence-based candidate gene prioritization approach for complex diseases-schizophrenia as a case , 2009, Bioinform..
[38] Ravi Iyengar,et al. Network analyses in systems pharmacology , 2009, Bioinform..
[39] Yanli Wang,et al. PubChem: a public information system for analyzing bioactivities of small molecules , 2009, Nucleic Acids Res..
[40] John P. Overington,et al. Genomic-scale prioritization of drug targets: the TDR Targets database , 2008, Nature Reviews Drug Discovery.
[41] Robert B. Russell,et al. SuperTarget and Matador: resources for exploring drug-target relationships , 2007, Nucleic Acids Res..
[42] Michael Darsow,et al. ChEBI: a database and ontology for chemical entities of biological interest , 2007, Nucleic Acids Res..
[43] Xiaomin Luo,et al. PDTD: a web-accessible protein database for drug target identification , 2008, BMC Bioinformatics.
[44] A. Barabasi,et al. Drug—target network , 2007, Nature Biotechnology.
[45] Xin Wen,et al. BindingDB: a web-accessible database of experimentally determined protein–ligand binding affinities , 2006, Nucleic Acids Res..
[46] Tatiana A. Tatusova,et al. Entrez Gene: gene-centered information at NCBI , 2004, Nucleic Acids Res..
[47] S. Runyon,et al. Dopamine transporter ligands: recent developments and therapeutic potential. , 2006, Current topics in medicinal chemistry.
[48] P. Masand,et al. Polypharmacy in schizophrenia , 2006, International journal of psychiatry in clinical practice.
[49] Oliver Freudenreich,et al. Medical morbidity and mortality in schizophrenia: guidelines for psychiatrists. , 2005, The Journal of clinical psychiatry.
[50] T. Ashburn,et al. Drug repositioning: identifying and developing new uses for existing drugs , 2004, Nature Reviews Drug Discovery.
[51] I. Kola,et al. Can the pharmaceutical industry reduce attrition rates? , 2004, Nature Reviews Drug Discovery.
[52] F. Dickerson,et al. Comorbidity of Medical Illnesses Among Adults With Serious Mental Illness Who Are Receiving Community Psychiatric Services , 2004, The Journal of nervous and mental disease.
[53] T. Hubbard,et al. A census of human cancer genes , 2004, Nature Reviews Cancer.
[54] B. Roth,et al. The Multiplicity of Serotonin Receptors: Uselessly Diverse Molecules or an Embarrassment of Riches? , 2000 .
[55] Hiroyuki Ogata,et al. KEGG: Kyoto Encyclopedia of Genes and Genomes , 1999, Nucleic Acids Res..