Tiny endoscopic optical coherence tomography probe driven by a miniaturized hollow ultrasonic motor

Abstract. We present an endoscopic probe for optical coherence tomography (OCT) equipped with a miniaturized hollow ultrasonic motor that rotates the objective lens and provides an internal channel for the fiber to pass through, enabling 360 deg unobstructed circumferential scanning. This probe has an outer diameter of 1.5 mm, which is ultra-small for motorized probes with an unobstructed view in distal scanning endoscopic OCT. Instead of a mirror or prism, a customized aspheric right-angle lens is utilized, leading to an enlargement of the numerical aperture and thus high transverse resolution. Spectral-domain OCT imaging of bio-tissue and a phantom are demonstrated with resolution of 7.5  μm(axial)×6.6  μm(lateral) and sensitivity of 96 dB.

[1]  Matthew Brenner,et al.  In vivo endoscopic optical coherence tomography by use of a rotational microelectromechanical system probe. , 2004, Optics letters.

[2]  Shoude Chang,et al.  Stationary-fiber rotary probe with unobstructed 360° view for optical coherence tomography. , 2011, Optics letters.

[3]  J G Fujimoto,et al.  Micromotor endoscope catheter for in vivo, ultrahigh-resolution optical coherence tomography. , 2004, Optics letters.

[4]  J. Fujimoto,et al.  Optical Coherence Tomography , 1991, LEOS '92 Conference Proceedings.

[5]  Huikai Xie,et al.  Miniature endoscopic optical coherence tomography probe employing a two-axis microelectromechanical scanning mirror with through-silicon vias. , 2011, Journal of biomedical optics.

[6]  T. Zhou,et al.  A cylindrical rod ultrasonic motor with 1 mm diameter and its application in endoscopic OCT , 2005 .

[7]  Benjamin J Vakoc,et al.  Three-dimensional coronary artery microscopy by intracoronary optical frequency domain imaging. , 2008, JACC. Cardiovascular imaging.

[8]  Yu Du,et al.  Compact MEMS-driven pyramidal polygon reflector for circumferential scanned endoscopic imaging probe. , 2012, Optics express.

[9]  A. Boccara,et al.  High-resolution full-field optical coherence tomography with a Linnik microscope. , 2002, Applied optics.

[10]  Hans Zappe,et al.  Integrated three-dimensional scanner for endoscopic optical coherence tomography , 2010, Photonics Europe.

[11]  Brett E Bouma,et al.  Two-axis magnetically-driven MEMS scanning catheter for endoscopic high-speed optical coherence tomography. , 2007, Optics express.

[12]  Yuxin Leng,et al.  Flexible miniature compound lens design for high-resolution optical coherence tomography balloon imaging catheter. , 2008, Journal of biomedical optics.

[13]  B E Bouma,et al.  Scanning single-mode fiber optic catheter-endoscope for optical coherence tomography: erratum. , 1996, Optics letters.

[14]  A. V. D. van der Steen,et al.  Intravascular optical coherence tomography imaging at 3200 frames per second. , 2013, Optics letters.

[15]  B. Golubovic,et al.  Single mode fiber-optic catheter/endoscope for optical coherence tomography , 1996, Summaries of papers presented at the Conference on Lasers and Electro-Optics.

[16]  G. Ripandelli,et al.  Optical coherence tomography. , 1998, Seminars in ophthalmology.

[17]  Ning Zhang,et al.  Spectral-domain optical coherence tomography with a Fresnel spectrometer. , 2012, Optics letters.

[18]  J. Fujimoto,et al.  In vivo endoscopic optical biopsy with optical coherence tomography. , 1997, Science.

[19]  Emily J. McDowell,et al.  Methods and application areas of endoscopic optical coherence tomography. , 2006, Journal of biomedical optics.