The erosion and abrasion-inhibiting effect of TiF(4) and NaF varnishes and solutions on enamel in vitro.

OBJECTIVE. Previous in vitro study has shown that TiF(4) varnish might reduce enamel erosion. No data regarding the effect of this experimental varnish on enamel erosion plus abrasion, however, are available so far. Thus, this in vitro study aimed to analyse the effect of TiF(4) compared with NaF varnishes and solutions, to protect against enamel erosion with or without abrasion. METHODS. Enamel specimens were pre-treated with experimental-TiF(4) (2.45% F), experimental-NaF (2.45% F), NaF-Duraphat (2.26% F), and placebo varnishes; NaF (2.26% F) and TiF(4) (2.45% F) solutions. Controls remained untreated. The erosive challenge was performed using a soft drink (pH 2.6) 4 × 90 s/day (ERO) and the toothbrushing abrasion (ERO+ABR) 2 × 10 s/day, for 5 days. Between the challenges, the specimens were exposed to artificial saliva. Enamel loss was measured profilometrically (μm). RESULTS. Kruskal-Wallis/Dunn tests showed that all fluoridated varnishes (TiF(4) -ERO:0.53 ± 0.20, ERO+ABR:0.65 ± 0.19/NaF-ERO:0.94 ± 0.18, ERO+ABR:1.74 ± 0.37/Duraphat-ERO:1.00 ± 0.37, ERO+ABR:1.72 ± 0.58) were able to significantly reduce enamel loss when compared with placebo varnish (ERO:3.45 ± 0.41/ERO+ABR:3.20 ± 0.66) (P < 0.0001). Placebo varnish, control (ERO:2.68 ± 0.53/ERO+ABR:3.01 ± 0.34), and fluoridated (NaF-ERO:2.84 ± 0.09/ERO+ABR:2.40 ± 0.21/TiF(4) -ERO:3.55 ± 0.59/ERO+ABR:4.10 ± 0.38) solutions did not significantly differ from each other. CONCLUSION. Based on the results, it can be concluded that the TiF(4) varnish seems to be a promising treatment to reduce enamel loss under mild erosive and abrasive conditions in vitro.

[1]  T. Attin,et al.  Effects of Various Fluoride Solutions on Enamel Erosion in vitro , 2010, Caries Research.

[2]  T. Attin,et al.  Effect of TiF4, ZrF4, HfF4 and AmF on erosion and erosion/abrasion of enamel and dentin in situ. , 2010, Archives of oral biology.

[3]  M. Buzalaf,et al.  Effect of a single application of TiF(4) and NaF varnishes and solutions on dentin erosion in vitro. , 2010, Journal of dentistry.

[4]  T. Attin,et al.  Comparison of the Effects of TiF4 and NaF Solutions at pH 1.2 and 3.5 on Enamel Erosion in vitro , 2009, Caries Research.

[5]  A. Lussi,et al.  Controlled Toothbrush Abrasion of Softened Human Enamel , 2008, Caries Research.

[6]  T. Attin,et al.  The Effect of an Experimental 4% TiF4Varnish Compared to NaF Varnishes and 4% TiF4Solution on Dental Erosion in vitro , 2008, Caries Research.

[7]  M. Buzalaf,et al.  Effect of 4% titanium tetrafluoride solution on dental erosion by a soft drink: an in situ/ex vivo study. , 2008, Archives of oral biology.

[8]  L. Hove,et al.  The Protective Effect of TiF4, SnF2 and NaF against Erosion-Like Lesions in situ , 2007, Caries Research.

[9]  M. Buzalaf,et al.  Effect of an experimental 4% titanium tetrafluoride varnish on dental erosion by a soft drink. , 2007, Journal of dentistry.

[10]  N. Schlueter,et al.  Effect of Titanium Tetrafluoride and Sodium Fluoride on Erosion Progression in Enamel and Dentine in vitro , 2007, Caries Research.

[11]  N. Schlueter,et al.  Retention of KOH-soluble fluoride on enamel and dentine under erosive conditions--A comparison of in vitro and in situ results. , 2007, Archives of oral biology.

[12]  L. Hove,et al.  An in vitro Study on the Effect of TiF4 Treatment against Erosion by Hydrochloric Acid on Pellicle-Covered Enamel , 2006, Caries Research.

[13]  B. Øgaard,et al.  The Protective Effect of TiF4, SnF2 and NaF on Erosion of Enamel by Hydrochloric Acid in vitro Measured by White Light Interferometry , 2006, Caries Research.

[14]  M. Huysmans,et al.  Brushing Abrasion of Eroded Bovine Enamel Pretreated with Topical Fluorides , 2006, Caries Research.

[15]  M. Buzalaf,et al.  Effect of Salivary Stimulation on Erosion of Human and Bovine Enamel Subjected or Not to Subsequent Abrasion: An in situ/ex vivo Study , 2006, Caries Research.

[16]  M. Barbosa,et al.  The uptake of titanium ions by hydroxyapatite particles-structural changes and possible mechanisms. , 2006, Biomaterials.

[17]  M. Addy,et al.  Interaction between attrition,abrasion and erosion in tooth wear. , 2006, Monographs in oral science.

[18]  D. Bartlett.  Intrinsic causes of erosion. , 2006, Monographs in oral science.

[19]  M. Huysmans,et al.  Effect of Titanium Tetrafluoride, Amine Fluoride and Fluoride Varnish on Enamel Erosion in vitro , 2005, Caries Research.

[20]  C. Ganss,et al.  Effects of Two Fluoridation Measures on Erosion Progression in Human Enamel and Dentine in situ , 2001, Caries Research.

[21]  G. Truin,et al.  Erosion-inhibiting effect of sodium fluoride and titanium tetrafluoride treatment in vitro. , 2003, European journal of oral sciences.

[22]  A. Lussi,et al.  The Role of Diet in the Aetiology of Dental Erosion , 2003, Caries Research.

[23]  T. Attin,et al.  Influence of fluoride on the prevention of erosive lesions--a review. , 2003, Oral health & preventive dentistry.

[24]  H. Tezel,et al.  Effects of topical fluoride agents on artificial enamel lesion formation in vitro. , 2002, Quintessence international.

[25]  T. Attin,et al.  In situ Evaluation of Different Remineralization Periods to Decrease Brushing Abrasion of Demineralized Enamel , 2001, Caries Research.

[26]  J. M. Cate.  Review on fluoride, with special emphasis on calcium fluoride mechanisms in caries prevention , 1997 .

[27]  B. Ogaard,et al.  The resistance of titanium tetrafluoride-treated human enamel to strong hydrochloric acid. , 1997, European journal of oral sciences.

[28]  E. Saxegaard,et al.  Fluoride acquisition on and in human enamel during topical application in vitro. , 1988, Scandinavian journal of dental research.

[29]  E. Hellwig,et al.  Fluoride taken up by plaque, by the underlying enamel and by clean enamel from three fluoride compounds in vitro. , 1982, Caries research.