Single-cell transcriptomic profiling of kidney fibrosis identifies a novel specific fibroblast marker and putative disease target
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D. Lindquist | M. Adam | P. Devarajan | Andrew S. Potter | Íñigo Valiente-Alandí | Q. Ma | D. Vanhoutte | M. Nieman | S. Potter | J. Kofron | Valeria Rudman-Melnick | Kaitlynn Stowers | Saagar M. Chokshi | Mike Adam
[1] P. Boor,et al. New Aspects of Kidney Fibrosis–From Mechanisms of Injury to Modulation of Disease , 2022, Frontiers in Medicine.
[2] Haojia Wu,et al. Spatially Resolved Transcriptomic Analysis of Acute Kidney Injury in a Female Murine Model , 2021, Journal of the American Society of Nephrology : JASN.
[3] A. McMahon,et al. Single-nuclear transcriptomics reveals diversity of proximal tubule cell states in a dynamic response to acute kidney injury , 2021, Proceedings of the National Academy of Sciences.
[4] P. Taylor,et al. Single-Nucleus RNA Sequencing Identifies New Classes of Proximal Tubular Epithelial Cells in Kidney Fibrosis , 2021, Journal of the American Society of Nephrology : JASN.
[5] X. Xuei,et al. Integration of spatial and single-cell transcriptomics localizes epithelial cell–immune cross-talk in kidney injury , 2021, JCI insight.
[6] M. Yanagita,et al. Fibroblast heterogeneity and tertiary lymphoid tissues in the kidney , 2021, Immunological reviews.
[7] Mingyao Li,et al. Single cell regulatory landscape of the mouse kidney highlights cellular differentiation programs and disease targets , 2021, Nature Communications.
[8] C. Gandhi,et al. MRI Measures of Murine Liver Fibrosis , 2021, Journal of magnetic resonance imaging : JMRI.
[9] E. Carney. The molecular genetics of AKI , 2020, Nature Reviews Nephrology.
[10] Victor G. Puelles,et al. Decoding myofibroblast origins in human kidney fibrosis , 2020, Nature.
[11] S. Potter,et al. Single-Cell Profiling of AKI in a Murine Model Reveals Novel Transcriptional Signatures, Profibrotic Phenotype, and Epithelial-to-Stromal Crosstalk. , 2020, Journal of the American Society of Nephrology : JASN.
[12] S. Zhuang,et al. New Insights Into the Role and Mechanism of Partial Epithelial-Mesenchymal Transition in Kidney Fibrosis , 2020, Frontiers in Physiology.
[13] J. Björkegren,et al. Single-cell analysis uncovers fibroblast heterogeneity and criteria for fibroblast and mural cell identification and discrimination , 2020, Nature Communications.
[14] Chengbo He,et al. Single‐cell RNA sequencing analysis of human kidney reveals the presence of ACE2 receptor: A potential pathway of COVID‐19 infection , 2020, Molecular genetics & genomic medicine.
[15] Leonard D. Goldstein,et al. Single-Cell Transcriptome Profiling of the Kidney Glomerulus Identifies Key Cell Types and Reactions to Injury. , 2020, Journal of the American Society of Nephrology : JASN.
[16] Haojia Wu,et al. Cell profiling of mouse acute kidney injury reveals conserved cellular responses to injury , 2020, Proceedings of the National Academy of Sciences.
[17] P. Devarajan. The Current State of the Art in Acute Kidney Injury , 2020, Frontiers in Pediatrics.
[18] Eunah Chung,et al. Hnf4a is required for the development of Cdh6-expressing progenitors into proximal tubules in the mouse kidney , 2020, bioRxiv.
[19] E. Neilson,et al. Origin and functional heterogeneity of fibroblasts , 2020, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[20] L. G. Vu,et al. Global, regional, and national burden of chronic kidney disease, 1990–2017: a systematic analysis for the Global Burden of Disease Study 2017 , 2020, The Lancet.
[21] J. M. Mora-Gutiérrez,et al. Matrix Metalloproteinases in Diabetic Kidney Disease , 2020, Journal of clinical medicine.
[22] H. Morgenstern,et al. US Renal Data System 2019 Annual Data Report: Epidemiology of Kidney Disease in the United States. , 2019, American journal of kidney diseases : the official journal of the National Kidney Foundation.
[23] A. Oshlack,et al. Single cell analysis of the developing mouse kidney provides deeper insight into marker gene expression and ligand-receptor crosstalk , 2019, Development.
[24] C. Altmann,et al. Matching Human Unilateral AKI, a Reverse Translational Approach to Investigate Kidney Recovery after Ischemia. , 2019, Journal of the American Society of Nephrology : JASN.
[25] J. Pedraza-Chaverri,et al. Unilateral Ureteral Obstruction as a Model to Investigate Fibrosis-Attenuating Treatments , 2019, Biomolecules.
[26] J. Lv,et al. Prevalence and Disease Burden of Chronic Kidney Disease. , 2019, Advances in experimental medicine and biology.
[27] Andrew S. Potter,et al. Dissociation of Tissues for Single-Cell Analysis. , 2019, Methods in molecular biology.
[28] Christoph Hafemeister,et al. Comprehensive integration of single cell data , 2018, bioRxiv.
[29] M. Bennett,et al. Disease-relevant transcriptional signatures identified in individual smooth muscle cells from healthy mouse vessels , 2018, Nature Communications.
[30] M. Kennedy,et al. NMR-based urine metabolic profiling and immunohistochemistry analysis of nephron changes in a mouse model of hypoxia-induced acute kidney injury. , 2018, American journal of physiology. Renal physiology.
[31] Z. Wang,et al. Vimentin expression is required for the development of EMT-related renal fibrosis following unilateral ureteral obstruction in mice. , 2018, American journal of physiology. Renal physiology.
[32] In Hye Lee,et al. Ahnak promotes tumor metastasis through transforming growth factor-β-mediated epithelial-mesenchymal transition , 2018, Scientific Reports.
[33] Mingyao Li,et al. Single-cell transcriptomics of the mouse kidney reveals potential cellular targets of kidney disease , 2018, Science.
[34] H. Castrop,et al. Renal Interstitial Platelet-Derived Growth Factor Receptor-β Cells Support Proximal Tubular Regeneration. , 2018, Journal of the American Society of Nephrology : JASN.
[35] B. Humphreys. Mechanisms of Renal Fibrosis. , 2018, Annual review of physiology.
[36] Hannah A. Pliner,et al. Reversed graph embedding resolves complex single-cell trajectories , 2017, Nature Methods.
[37] H. Tan,et al. Evaluation of Renal Blood Flow in Chronic Kidney Disease Using Arterial Spin Labeling Perfusion Magnetic Resonance Imaging , 2016, Kidney international reports.
[38] M. Little,et al. Does Renal Repair Recapitulate Kidney Development? , 2017, Journal of the American Society of Nephrology : JASN.
[39] Youhua Liu,et al. Signaling Crosstalk between Tubular Epithelial Cells and Interstitial Fibroblasts after Kidney Injury , 2016, Kidney Diseases.
[40] B. Vervaet,et al. Unilateral Renal Ischemia-Reperfusion as a Robust Model for Acute to Chronic Kidney Injury in Mice , 2016, PloS one.
[41] Evan Z. Macosko,et al. Highly Parallel Genome-wide Expression Profiling of Individual Cells Using Nanoliter Droplets , 2015, Cell.
[42] R. Li,et al. Role of bone morphogenetic protein-7 in renal fibrosis , 2015, Front. Physiol..
[43] B. Ebert,et al. Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis. , 2015, Cell stem cell.
[44] Derek W Wright,et al. Gateways to the FANTOM5 promoter level mammalian expression atlas , 2015, Genome Biology.
[45] Roland Eils,et al. circlize implements and enhances circular visualization in R , 2014, Bioinform..
[46] A. McMahon,et al. Translational profiles of medullary myofibroblasts during kidney fibrosis. , 2014, Journal of the American Society of Nephrology : JASN.
[47] J. Duffield. Cellular and molecular mechanisms in kidney fibrosis. , 2014, The Journal of clinical investigation.
[48] Rafael Kramann,et al. Differentiated kidney epithelial cells repair injured proximal tubule , 2013, Proceedings of the National Academy of Sciences.
[49] R. Kramann,et al. Matrix-Producing Cells in Chronic Kidney Disease: Origin, Regulation, and Activation , 2013, Current Pathobiology Reports.
[50] R. Kalluri,et al. Origin and function of myofibroblasts in kidney fibrosis , 2013, Nature Medicine.
[51] Michel G. Arsenault,et al. The transcription factor sry‐related HMG box‐4 (SOX4) is required for normal renal development in vivo , 2013, Developmental dynamics : an official publication of the American Association of Anatomists.
[52] S. Gharib,et al. Cellular mechanisms of tissue fibrosis. 3. Novel mechanisms of kidney fibrosis. , 2013, American journal of physiology. Cell physiology.
[53] B. Coulomb,et al. The myofibroblast, multiple origins for major roles in normal and pathological tissue repair , 2012, Fibrogenesis & tissue repair.
[54] Y. Fukuda,et al. Involvement of matrix metalloproteinase-2 in the development of renal interstitial fibrosis in mouse obstructive nephropathy , 2012, Laboratory Investigation.
[55] Livia Puljak,et al. The interstitial expression of alpha-smooth muscle actin in glomerulonephritis is associated with renal function , 2012, Medical science monitor : international medical journal of experimental and clinical research.
[56] Josef Coresh,et al. Chronic kidney disease , 2012, The Lancet.
[57] R. Baldock,et al. The GUDMAP database – an online resource for genitourinary research , 2011, Development.
[58] M. Yoder,et al. Ontogeny of CD24 in the human kidney. , 2010, Kidney international.
[59] P. Zheng,et al. CD24: from A to Z , 2010, Cellular and Molecular Immunology.
[60] Jing Chen,et al. ToppGene Suite for gene list enrichment analysis and candidate gene prioritization , 2009, Nucleic Acids Res..
[61] D. Brenner,et al. Pericytes and perivascular fibroblasts are the primary source of collagen-producing cells in obstructive fibrosis of the kidney. , 2008, The American journal of pathology.
[62] A. Reymond,et al. Knobloch syndrome: Novel mutations in COL18A1, evidence for genetic heterogeneity, and a functionally impaired polymorphism in endostatin , 2004, Human Mutation.
[63] S. Paydaş,et al. The expression of cytoskeletal proteins (α-SMA, vimentin, desmin) in kidney tissue: A comparison of fetal, normal kidneys, and glomerulonephritis , 2004, International Urology and Nephrology.
[64] Bruce J Aronow,et al. A catalogue of gene expression in the developing kidney. , 2003, Kidney international.
[65] P. Igarashi,et al. Epithelial-specific Cre/lox recombination in the developing kidney and genitourinary tract. , 2002, Journal of the American Society of Nephrology : JASN.
[66] P. Kingsley,et al. Osr2, a new mouse gene related to Drosophila odd-skipped, exhibits dynamic expression patterns during craniofacial, limb, and kidney development , 2001, Mechanisms of Development.
[67] B. Eyden. The Myofibroblast: An Assessment of Controversial Issues and a Definition Useful in Diagnosis and Research , 2001, Ultrastructural pathology.
[68] M. Goulding,et al. Kidney development in cadherin-6 mutants: delayed mesenchyme-to-epithelial conversion and loss of nephrons. , 2000, Developmental biology.
[69] D. Salant,et al. Expression of type I collagen mRNA in glomeruli of rats with passive Heymann nephritis. , 1993, Kidney international.