Antihyperalgesic effects of dexketoprofen and tramadol in a model of postoperative pain in mice – effects on glial cell activation

To define likely targets (i.e. glia) and protocols (analgesic combinations) to improve postoperative pain outcomes and reduce chronic pain after surgery. Specifically, to assess the antihyperalgesic effects of the dexketoprofen : tramadol (DEX : TRM) combination, exploring the implication of glial activation.

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