Nature or Nurture: Innate versus Cultured Mesenchymal Stem Cells for Tissue Regeneration

[1]  G. Angelini,et al.  Combined intramyocardial delivery of human pericytes and cardiac stem cells additively improves the healing of mouse infarcted hearts through stimulation of vascular and muscular repair. , 2015, Circulation research.

[2]  D. Prockop,et al.  Are Clinical Trials With Mesenchymal Stem/Progenitor Cells too Far Ahead of the Science? Lessons From Experimental Hematology , 2014, Stem cells.

[3]  G. Xiang,et al.  Human Myocardial Pericytes: Multipotent Mesodermal Precursors Exhibiting Cardiac Specificity , 2014, Stem cells.

[4]  Le Chang,et al.  Human Perivascular Stem Cell‐Based Bone Graft Substitute Induces Rat Spinal Fusion , 2014, Stem cells translational medicine.

[5]  Charles E. Murry,et al.  Human Embryonic Stem Cell-Derived Cardiomyocytes Regenerate Non-Human Primate Hearts , 2014, Nature.

[6]  A. James,et al.  Natural history of mesenchymal stem cells, from vessel walls to culture vessels , 2014, Cellular and Molecular Life Sciences.

[7]  A. Tyndall.  Mesenchymal stem cell treatments in rheumatology—a glass half full? , 2014, Nature Reviews Rheumatology.

[8]  Mihaela Crisan,et al.  Identification of perivascular mesenchymal stromal/stem cells by flow cytometry , 2013, Cytometry. Part A : the journal of the International Society for Analytical Cytology.

[9]  K. Ozawa,et al.  Unrelated allogeneic bone marrow-derived mesenchymal stem cells for steroid-refractory acute graft-versus-host disease: a phase I/II study , 2013, International Journal of Hematology.

[10]  Yu-fang Shi,et al.  Mesenchymal stem cells: a new trend for cell therapy , 2013, Acta Pharmacologica Sinica.

[11]  J. Mullins,et al.  Erratum to: Renal pericytes: multifunctional cells of the kidneys , 2013, Pflügers Archiv - European Journal of Physiology.

[12]  Stefańska Am,et al.  Renal pericytes: multifunctional cells of the kidneys , 2013, Pflügers Archiv - European Journal of Physiology.

[13]  G. Crooks,et al.  Perivascular support of human hematopoietic stem/progenitor cells. , 2013, Blood.

[14]  Bruno Péault,et al.  Explorer Human Perivascular Stem Cells Show Enhanced Osteogenesis and Vasculogenesis with Nel-Like Molecule I Protein , 2007 .

[15]  R. Katare,et al.  Pericytes from human veins for treatment of myocardial ischemia. , 2013, Trends in cardiovascular medicine.

[16]  K. Tobita,et al.  Human Pericytes for Ischemic Heart Repair , 2013, Stem cells.

[17]  P. Layrolle,et al.  Pericyte-Like Progenitors Show High Immaturity and Engraftment Potential as Compared with Mesenchymal Stem Cells , 2012, PloS one.

[18]  W. Sandborn,et al.  Crohn's disease , 2012, The Lancet.

[19]  A. Nguyen,et al.  An Abundant Perivascular Source of Stem Cells for Bone Tissue Engineering , 2012, Stem cells translational medicine.

[20]  Ulrich Wagner,et al.  Follicular Dendritic Cells Emerge from Ubiquitous Perivascular Precursors , 2012, Cell.

[21]  Le Chang,et al.  Perivascular Stem Cells: A Prospectively Purified Mesenchymal Stem Cell Population for Bone Tissue Engineering , 2012, Stem cells translational medicine.

[22]  Min Lee,et al.  Use of Human Perivascular Stem Cells for Bone Regeneration , 2012, Journal of visualized experiments : JoVE.

[23]  M. Corselli,et al.  The tunica adventitia of human arteries and veins as a source of mesenchymal stem cells. , 2012, Stem cells and development.

[24]  N. S. Asli,et al.  Adult cardiac-resident MSC-like stem cells with a proepicardial origin. , 2011, Cell stem cell.

[25]  Li Qian,et al.  In vivo reprogramming of murine cardiac fibroblasts into induced cardiomyocytes , 2011, Nature.

[26]  G. Pals,et al.  Osteogenesis Imperfecta: A Review with Clinical Examples , 2011, Molecular Syndromology.

[27]  S. Antonini,et al.  Pericytes resident in postnatal skeletal muscle differentiate into muscle fibres and generate satellite cells. , 2011, Nature communications.

[28]  G. Angelini,et al.  Transplantation of Human Pericyte Progenitor Cells Improves the Repair of Infarcted Heart Through Activation of an Angiogenic Program Involving Micro-RNA-132 , 2011, Circulation research.

[29]  Mark F. Lythgoe,et al.  De novo cardiomyocytes from within the activated adult heart after injury , 2011, Nature.

[30]  Philippe Soriano,et al.  PDGFRβ signaling regulates mural cell plasticity and inhibits fat development. , 2011, Developmental cell.

[31]  M. Corselli,et al.  Multilineage stem cells in the adult , 2011, Organogenesis.

[32]  J. Huard,et al.  Placental perivascular cells for human muscle regeneration. , 2011, Stem cells and development.

[33]  Benjamin M. Wu,et al.  Nell-1 protein promotes bone formation in a sheep spinal fusion model. , 2011, Tissue engineering. Part A.

[34]  O. Ringdén,et al.  Mesenchymal stromal cells as treatment for chronic GVHD , 2011, Bone Marrow Transplantation.

[35]  A. Caplan,et al.  Mesenchymal stem cells: mechanisms of inflammation. , 2011, Annual review of pathology.

[36]  Franco Locatelli,et al.  Autologous bone marrow-derived mesenchymal stromal cells in the treatment of fistulising Crohn's disease , 2011, Gut.

[37]  D. Vorp,et al.  Pericyte-based human tissue engineered vascular grafts. , 2010, Biomaterials.

[38]  P. Pattany,et al.  Bone Marrow Mesenchymal Stem Cells Stimulate Cardiac Stem Cell Proliferation and Differentiation , 2010, Circulation research.

[39]  M. Corselli,et al.  Perivascular Ancestors of Adult Multipotent Stem Cells , 2010, Arteriosclerosis, thrombosis, and vascular biology.

[40]  Benjamin M. Wu,et al.  Delivery of lyophilized Nell-1 in a rat spinal fusion model. , 2010, Tissue engineering. Part A.

[41]  Joshua M Hare,et al.  A randomized, double-blind, placebo-controlled, dose-escalation study of intravenous adult human mesenchymal stem cells (prochymal) after acute myocardial infarction. , 2009, Journal of the American College of Cardiology.

[42]  M. Soleimani,et al.  Improvement of liver function in liver cirrhosis patients after autologous mesenchymal stem cell injection: a phase I–II clinical trial , 2009, European journal of gastroenterology & hepatology.

[43]  J. Huard,et al.  Perivascular multi-lineage progenitor cells in human organs: regenerative units, cytokine sources or both? , 2009, Cytokine & growth factor reviews.

[44]  S. Brand.  Crohn’s disease: Th1, Th17 or both? The change of a paradigm: new immunological and genetic insights implicate Th17 cells in the pathogenesis of Crohn’s disease , 2009, Gut.

[45]  L. Isola,et al.  Adult human mesenchymal stem cells added to corticosteroid therapy for the treatment of acute graft-versus-host disease. , 2009, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.

[46]  C. Gargett,et al.  Isolation and Culture of Epithelial Progenitors and Mesenchymal Stem Cells from Human Endometrium1 , 2009, Biology of reproduction.

[47]  Jeffrey M Karp,et al.  Mesenchymal stem cell homing: the devil is in the details. , 2009, Cell stem cell.

[48]  R. Hammer,et al.  White Fat Progenitor Cells Reside in the Adipose Vasculature , 2008, Science.

[49]  E. Rosen,et al.  IFATS Collection: Adipose Stromal Cell Differentiation Is Reduced by Endothelial Cell Contact and Paracrine Communication: Role of Canonical Wnt Signaling , 2008, Stem cells.

[50]  Arnold I Caplan,et al.  All MSCs are pericytes? , 2008, Cell stem cell.

[51]  S. Badylak,et al.  A perivascular origin for mesenchymal stem cells in multiple human organs. , 2008, Cell stem cell.

[52]  N. Nardi,et al.  In Search of the In Vivo Identity of Mesenchymal Stem Cells , 2008, Stem cells.

[53]  G. Dini,et al.  Mesenchymal stem cells for treatment of steroid-resistant, severe, acute graft-versus-host disease: a phase II study , 2008, The Lancet.

[54]  F. Prósper,et al.  Transplantation of adipose derived stromal cells is associated with functional improvement in a rat model of chronic myocardial infarction , 2008, European journal of heart failure.

[55]  M. Zago,et al.  Multipotent mesenchymal stromal cells obtained from diverse human tissues share functional properties and gene-expression profile with CD146+ perivascular cells and fibroblasts. , 2008, Experimental hematology.

[56]  A. Ochiai,et al.  Human vascular adventitial fibroblasts contain mesenchymal stem/progenitor cells. , 2008, Biochemical and biophysical research communications.

[57]  J. Gimble,et al.  Multipotential human adipose‐derived stromal stem cells exhibit a perivascular phenotype in vitro and in vivo , 2008, Journal of cellular physiology.

[58]  W. Arap,et al.  A Population of Multipotent CD34-Positive Adipose Stromal Cells Share Pericyte and Mesenchymal Surface Markers, Reside in a Periendothelial Location, and Stabilize Endothelial Networks , 2008, Circulation research.

[59]  C. Gargett,et al.  Co-expression of two perivascular cell markers isolates mesenchymal stem-like cells from human endometrium. , 2007, Human reproduction.

[60]  B. Zheng,et al.  Prospective identification of myogenic endothelial cells in human skeletal muscle , 2007, Nature Biotechnology.

[61]  F. Martinez,et al.  Evidence for tissue-resident mesenchymal stem cells in human adult lung from studies of transplanted allografts. , 2007, The Journal of clinical investigation.

[62]  A. Bacigalupo.  Management of acute graft‐versus‐host disease , 2007, British journal of haematology.

[63]  B. Sacchetti,et al.  Pericytes of human skeletal muscle are myogenic precursors distinct from satellite cells , 2007, Nature Cell Biology.

[64]  J. Hare,et al.  Mechanisms of action of mesenchymal stem cells in cardiac repair: potential influences on the cardiac stem cell niche , 2007, Nature Clinical Practice Cardiovascular Medicine.

[65]  Arjun Deb,et al.  Secreted frizzled related protein 2 (Sfrp2) is the key Akt-mesenchymal stem cell-released paracrine factor mediating myocardial survival and repair , 2007, Proceedings of the National Academy of Sciences.

[66]  T. Asahara,et al.  CD34-Positive Cells Exhibit Increased Potency and Safety for Therapeutic Neovascularization After Myocardial Infarction Compared With Total Mononuclear Cells , 2006, Circulation.

[67]  A. Caplan,et al.  Mesenchymal stem cells as trophic mediators , 2006, Journal of cellular biochemistry.

[68]  H. Drexler,et al.  Impact of intracoronary bone marrow cell transfer on diastolic function in patients after acute myocardial infarction: results from the BOOST trial. , 2006, European heart journal.

[69]  W. Ansorge,et al.  Comparative characteristics of mesenchymal stem cells from human bone marrow, adipose tissue, and umbilical cord blood. , 2005, Experimental hematology.

[70]  H. Ohgushi,et al.  Transplantation of Mesenchymal Stem Cells Improves Cardiac Function in a Rat Model of Dilated Cardiomyopathy , 2005, Circulation.

[71]  Daria Nurzynska,et al.  Myocardial regeneration by activation of multipotent cardiac stem cells in ischemic heart failure. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[72]  M. Pittenger,et al.  Human mesenchymal stem cells modulate allogeneic immune cell responses. , 2005, Blood.

[73]  Dolores Baksh,et al.  Human Umbilical Cord Perivascular (HUCPV) Cells: A Source of Mesenchymal Progenitors , 2005, Stem cells.

[74]  D. Riethmacher,et al.  Progenitor cells of the testosterone-producing Leydig cells revealed , 2004, The Journal of cell biology.

[75]  Bernd Hertenstein,et al.  Intracoronary autologous bone-marrow cell transfer after myocardial infarction: the BOOST randomised controlled clinical trial , 2004, The Lancet.

[76]  Fei Ye,et al.  Effect on left ventricular function of intracoronary transplantation of autologous bone marrow mesenchymal stem cell in patients with acute myocardial infarction. , 2004, The American journal of cardiology.

[77]  F. Barry,et al.  Mesenchymal stem cells: clinical applications and biological characterization. , 2004, The international journal of biochemistry & cell biology.

[78]  K. Watson,et al.  Multilineage Potential of Cells From the Artery Wall , 2003, Circulation.

[79]  R. Zhao,et al.  Isolation and identification of mesenchymal stem cells from human fetal pancreas. , 2003, The Journal of laboratory and clinical medicine.

[80]  S. Gronthos,et al.  Perivascular Niche of Postnatal Mesenchymal Stem Cells in Human Bone Marrow and Dental Pulp , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.

[81]  Y. Romanov,et al.  Searching for Alternative Sources of Postnatal Human Mesenchymal Stem Cells: Candidate MSC‐Like Cells from Umbilical Cord , 2003, Stem cells.

[82]  L. Muul,et al.  Isolated allogeneic bone marrow-derived mesenchymal cells engraft and stimulate growth in children with osteogenesis imperfecta: Implications for cell therapy of bone , 2002, Proceedings of the National Academy of Sciences of the United States of America.

[83]  T. Suda,et al.  Mesenchymal Stem Cells in Perichondrium Express Activated Leukocyte Cell Adhesion Molecule and Participate in Bone Marrow Formation , 2002, The Journal of experimental medicine.

[84]  T. Steele,et al.  Human reserve pluripotent mesenchymal stem cells are present in the connective tissues of skeletal muscle and dermis derived from fetal, adult, and geriatric donors , 2001, The Anatomical record.

[85]  F. Luyten,et al.  Multipotent mesenchymal stem cells from adult human synovial membrane. , 2001, Arthritis and rheumatism.

[86]  H. Lorenz,et al.  Multilineage cells from human adipose tissue: implications for cell-based therapies. , 2001, Tissue engineering.

[87]  S. Gronthos,et al.  Postnatal human dental pulp stem cells (DPSCs) in vitro and in vivo. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[88]  M. Pittenger,et al.  Multilineage potential of adult human mesenchymal stem cells. , 1999, Science.

[89]  Darwin J. Prockop,et al.  Transplantability and therapeutic effects of bone marrow-derived mesenchymal cells in children with osteogenesis imperfecta , 1999, Nature Medicine.

[90]  Arnold I. Caplan,et al.  Mesenchymal Stem Cells , 1991, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[91]  A. Friedenstein,et al.  Thymus cells are inducible to osteogenesis , 1972, European journal of immunology.

[92]  A. Friedenstein,et al.  THE DEVELOPMENT OF FIBROBLAST COLONIES IN MONOLAYER CULTURES OF GUINEA‐PIG BONE MARROW AND SPLEEN CELLS , 1970, Cell and tissue kinetics.

[93]  R. Herrmann,et al.  A phase 2 study of allogeneic mesenchymal stromal cells for luminal Crohn's disease refractory to biologic therapy. , 2014, Clinical gastroenterology and hepatology : the official clinical practice journal of the American Gastroenterological Association.

[94]  A. Caplan,et al.  Serial transplantation and long-term engraftment of intra-arterially delivered clonally derived mesenchymal stem cells to injured bone marrow. , 2014, Molecular Therapy.

[95]  David H. Miller,et al.  Autologous mesenchymal stem cells for the treatment of secondary progressive multiple sclerosis: an open-label phase 2a proof-of-concept study , 2012, The Lancet Neurology.

[96]  K. Tobita,et al.  Human skeletal muscle cells with a slow adhesion rate after isolation and an enhanced stress resistance improve function of ischemic hearts. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

[97]  S. Badylak,et al.  Extracellular matrix degradation products and low-oxygen conditions enhance the regenerative potential of perivascular stem cells. , 2011, Tissue engineering. Part A.

[98]  S. Miller,et al.  Human bone marrow‐derived mesenchymal stem cells induce Th2‐polarized immune response and promote endogenous repair in animal models of multiple sclerosis , 2009, Glia.

[99]  Hajime Ohgushi,et al.  Repair of articular cartilage defects in the patello‐femoral joint with autologous bone marrow mesenchymal cell transplantation: three case reports involving nine defects in five knees , 2007, Journal of tissue engineering and regenerative medicine.

[100]  K. Then,et al.  Mesenchymal stromal cell-like characteristics of corneal keratocytes. , 2007, Cytotherapy.

[101]  D. Prockop,et al.  Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.

[102]  Holger Gerhardt,et al.  Role of pericytes in vascular morphogenesis. , 2005, EXS.

[103]  R. Willemze,et al.  Mesenchymal stem cells in human second-trimester bone marrow, liver, lung, and spleen exhibit a similar immunophenotype but a heterogeneous multilineage differentiation potential. , 2003, Haematologica.

[104]  A. Caplan,et al.  Cell surface antigens on human marrow-derived mesenchymal cells are detected by monoclonal antibodies. , 1992, Bone.

[105]  Extended Report , 2022 .

[106]  P. Rebulla,et al.  Differentiation and migration properties of human foetal umbilical cord perivascular cells: potential for lung repair , 2011, Journal of cellular and molecular medicine.