Knowledge-Based Approaches in Pharmacovigilance: Lessons and Prospects for Personalized Medicine

[1]  A. Venot,et al.  Appraisal of the MedDRA Conceptual Structure for Describing and Grouping Adverse Drug Reactions , 2005, Drug safety.

[2]  Michel Dumontier,et al.  Towards pharmacogenomics knowledge discovery with the semantic web , 2009, Briefings Bioinform..

[3]  M. Relling,et al.  Moving towards individualized medicine with pharmacogenomics , 2004, Nature.

[4]  M. Lindquist,et al.  Signal Selection and Follow-Up in Pharmacovigilance , 2002, Drug safety.

[5]  Patrice Degoulet,et al.  Terminology extraction from text to build an ontology in surgical intensive care , 2002, AMIA.

[6]  Spontaneous ADR Reports as a Trigger for Pharmacogenetic Research , 2009, Drug safety.

[7]  Howard L McLeod,et al.  Pharmacogenomics--drug disposition, drug targets, and side effects. , 2003, The New England journal of medicine.

[8]  Amedeo Napoli,et al.  Suggested Ontology for Pharmacogenomics (SO-Pharm): Modular Construction and Preliminary Testing , 2006, OTM Workshops.

[9]  I R Edwards,et al.  Harmonisation in Pharmacovigilance , 1994, Drug safety.

[10]  Rogers P Pole The GALEN High Level Ontology , 1996 .

[11]  Patrice Degoulet,et al.  Implementation of automated signal generation in pharmacovigilance using a knowledge-based approach , 2005, Int. J. Medical Informatics.

[12]  Volker Haarslev,et al.  Description of the RACER System and its Applications , 2001, Description Logics.

[13]  Jim Slattery,et al.  Validation of Statistical Signal Detection Procedures in EudraVigilance Post-Authorization Data , 2010, Drug safety.

[14]  Aldo Gangemi,et al.  Ontology Learning and Its Application to Automated Terminology Translation , 2003, IEEE Intell. Syst..

[15]  Michael Uschold,et al.  Ontologies: principles, methods and applications , 1996, The Knowledge Engineering Review.

[16]  Feng Liu,et al.  The pharmacogenetics and pharmacogenomics knowledge base: accentuating the knowledge , 2007, Nucleic Acids Res..

[17]  Marie-Christine Jaulent,et al.  A case report: using SNOMED CT for grouping Adverse Drug Reactions Terms , 2008, BMC Medical Informatics Decis. Mak..

[18]  M. Lindquist,et al.  A Retrospective Evaluation of a Data Mining Approach to Aid Finding New Adverse Drug Reaction Signals in the WHO International Database , 2000, Drug safety.

[19]  Russ B. Altman,et al.  Author ' s personal copy Using text to build semantic networks for pharmacogenomics , 2010 .

[20]  M. Hauben,et al.  Quantitative Methods in Pharmacovigilance , 2003, Drug safety.

[21]  P. Mozzicato,et al.  Standardised MedDRA Queries , 2007, Drug safety.

[22]  B Bégaud,et al.  Imputabilité des effets inattendus ou toxiques des médicaments: actualisation de la méthode utilisée en France , 1985 .

[23]  D. Lindberg,et al.  Unified Medical Language System , 2020, Definitions.

[24]  Christine Tonéatti,et al.  Experience using MedDRA for global events coding in HIV clinical trials. , 2006, Contemporary clinical trials.

[25]  Adam Wright,et al.  White paper: A Roadmap for National Action on Clinical Decision Support , 2007, J. Am. Medical Informatics Assoc..

[26]  D. Coulter,et al.  Linking Pharmacovigilance with Pharmacogenetics , 2004, Drug safety.

[27]  D. Clark,et al.  Drug metabolism genotypes and their association with adverse drug reactions in selected populations: a pilot study of methodology , 2000, Pharmacoepidemiology and drug safety.

[28]  Robert H. Baud,et al.  GALEN: a third generation terminology tool to support a multipurpose national coding system for surgical procedures , 2000, Int. J. Medical Informatics.

[29]  M. Lindquist,et al.  A Data Mining Approach for Signal Detection and Analysis , 2002, Drug safety.

[30]  A. Bate,et al.  A Bayesian neural network method for adverse drug reaction signal generation , 1998, European Journal of Clinical Pharmacology.

[31]  Ira J. Kalet,et al.  Feasibility of incorporating genomic knowledge into electronic medical records for pharmacogenomic clinical decision support , 2010, BMC Bioinformatics.

[32]  Thomas R. Gruber,et al.  A translation approach to portable ontology specifications , 1993, Knowl. Acquis..

[33]  Fleur Mougin,et al.  Mapping of the WHO-ART terminology on Snomed CT to improve grouping of related adverse drug reactions , 2006, MIE.

[34]  Y. Lussier,et al.  The SNOMED Model: A Knowledge Source for the Controlled Terminology of the Computerized Patient Record , 1998, Methods of Information in Medicine.

[35]  Ian Horrocks,et al.  Reasoning with Individuals for the Description Logic SHIQ , 2000, CADE.

[36]  J. Hanley Receiver operating characteristic (ROC) methodology: the state of the art. , 1989, Critical reviews in diagnostic imaging.

[37]  Russ B. Altman,et al.  Ontology Development for a Pharmacogenetics Knowledge Base , 2001, Pacific Symposium on Biocomputing.

[38]  B K Tang,et al.  Hypothesis: comparisons of inter- and intra-individual variations can substitute for twin studies in drug research. , 1998, Pharmacogenetics.

[39]  Ian Horrocks,et al.  OilEd: a Reason-able Ontology Editor for the Semantic Web , 2001, Description Logics.

[40]  E. Brown,et al.  Effects of Coding Dictionary on Signal Generation , 2002, Drug safety.

[41]  Werner Ceusters,et al.  Reconciling users' needs and formal requirements: issues in developing a reusable ontology for medicine , 1998, IEEE Transactions on Information Technology in Biomedicine.

[42]  I. Edwards,et al.  Adverse drug reactions: finding the needle in the haystack , 1997, BMJ.

[43]  R. O’Neill,et al.  Use of Screening Algorithms and Computer Systems to Efficiently Signal Higher-Than-Expected Combinations of Drugs and Events in the US FDA’s Spontaneous Reports Database , 2002, Drug safety.

[44]  Miki Yokotsuka,et al.  The use of a medical dictionary for regulatory activities terminology (MedDRA) in prescription-event monitoring in Japan (J-PEM) , 2000, Int. J. Medical Informatics.

[45]  R. Meyboom,et al.  Use of Measures of Disproportionality in Pharmacovigilance , 2002, Drug safety.

[46]  Bonnie Kaplan,et al.  Clinical decision support systems for the practice of evidence-based medicine. , 2001, Journal of the American Medical Informatics Association : JAMIA.

[47]  H. Hug,et al.  Ontology-based knowledge management of troglitazone-induced hepatotoxicity. , 2004, Drug discovery today.

[48]  Mark A. Musen,et al.  The Knowledge Model of Protégé-2000: Combining Interoperability and Flexibility , 2000, EKAW.

[49]  Richard Fikes,et al.  The Ontolingua Server: a tool for collaborative ontology construction , 1997, Int. J. Hum. Comput. Stud..

[50]  H. Willard,et al.  Genomic and personalized medicine: foundations and applications. , 2009, Translational research : the journal of laboratory and clinical medicine.

[51]  Patrice Degoulet,et al.  PharmARTS: Terminology Web Services for Drug Safety Data Coding and Retrieval , 2007, MedInfo.

[52]  A. Bate,et al.  Data-mining analyses of pharmacovigilance signals in relation to relevant comparison drugs , 2002, European Journal of Clinical Pharmacology.

[53]  Ronald Cornet,et al.  Auditing description-logic-based medical terminological systems by detecting equivalent concept definitions , 2008, Int. J. Medical Informatics.

[54]  Patrice Degoulet,et al.  Building an ontology of adverse drug reactions for automated signal generation in pharmacovigilance , 2006, Comput. Biol. Medicine.

[55]  H. Hug,et al.  ADRIS - The Adverse Drug Reactions Information Scheme. , 2003, Clinical neuropharmacology.

[56]  G. Ginsburg,et al.  Personalized medicine: revolutionizing drug discovery and patient care. , 2001, Trends in biotechnology.

[57]  E. Brown,et al.  The Medical Dictionary for Regulatory Activities (MedDRA) , 1999, Drug safety.

[58]  M Pirmohamed,et al.  Genetic susceptibility to adverse drug reactions. , 2001, Trends in pharmacological sciences.

[59]  M. Levine,et al.  Pharmacovigilance in a genomic era , 2006, The Pharmacogenomics Journal.

[60]  Prakash M. Nadkarni,et al.  Determining correspondences between high-frequency MedDRA concepts and SNOMED: a case study , 2010, BMC Medical Informatics Decis. Mak..

[61]  J E Rogers,et al.  Quality Assurance of Medical Ontologies , 2006, Methods of Information in Medicine.

[62]  William T. Hole,et al.  Research Paper: Integrating SNOMED CT into the UMLS: An Exploration of Different Views of Synonymy and Quality of Editing , 2005, J. Am. Medical Informatics Assoc..