Automatic optic disc segmentation with peripapillary atrophy elimination

Optic disc segmentation from retinal fundus image is a fundamental but important step for automatic glaucoma diagnosis. In this paper, an optic disc segmentation method is proposed based on peripapillary atrophy elimination. The elimination is done through edge filtering, constraint elliptical Hough transform and peripapillary atrophy detection. With the elimination, edges that are likely from non-disc structures especially peripapillary atrophy are excluded to make the segmentation more accurate. The proposed method has been tested in a database of 650 images with disc boundaries marked by trained professionals manually. The experimental results by the proposed method show average m1, m2 and mVD of 10.0%, 7.4% and 4.9% respectively. It can be used to compute cup to disc ratio as well as other features for application in automatic glaucoma diagnosis systems.

[1]  Huiqi Li,et al.  Boundary detection of optic disk by a modified ASM method , 2003, Pattern Recognit..

[2]  J. Canny A Computational Approach to Edge Detection , 1986, IEEE Transactions on Pattern Analysis and Machine Intelligence.

[3]  D O D Michael Hancox,et al.  Optic disc size, an important consideration in the glaucoma evaluation , 1999 .

[4]  Robert Ritch,et al.  The ISNT rule and differentiation of normal from glaucomatous eyes. , 2006, Archives of ophthalmology.

[5]  Tien Yin Wong,et al.  ORIGA-light: An online retinal fundus image database for glaucoma analysis and research , 2010, 2010 Annual International Conference of the IEEE Engineering in Medicine and Biology.

[6]  Tin Aung,et al.  Determinants of the optic cup to disc ratio in an Asian population: the Singapore Malay Eye Study (SiMES). , 2008, Archives of ophthalmology.

[7]  F Dannheim,et al.  Sensitivity and specificity of optic disc parameters in chronic glaucoma. , 1993, Investigative ophthalmology & visual science.

[8]  Rangaraj M. Rangayyan,et al.  Detection of the optic disc in images of the retina using the Hough transform , 2008, 2008 30th Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[9]  Juan Xu,et al.  Optic disk feature extraction via modified deformable model technique for glaucoma analysis , 2007, Pattern Recognit..

[10]  J. Jonas,et al.  Ophthalmoscopic evaluation of the optic nerve head. , 1999, Survey of ophthalmology.

[11]  Tien Yin Wong,et al.  Optic disc region of interest localization in fundus image for Glaucoma detection in ARGALI , 2010, 2010 5th IEEE Conference on Industrial Electronics and Applications.

[12]  G. G. Stokes "J." , 1890, The New Yale Book of Quotations.

[13]  Ying Sun,et al.  Convex hull based neuro-retinal optic cup ellipse optimization in glaucoma diagnosis , 2009, 2009 Annual International Conference of the IEEE Engineering in Medicine and Biology Society.

[14]  Michael H. Goldbaum,et al.  Locating the optic nerve in a retinal image using the fuzzy convergence of the blood vessels , 2003, IEEE Transactions on Medical Imaging.

[15]  Enrico Grisan,et al.  Detection of optic disc in retinal images by means of a geometrical model of vessel structure , 2004, IEEE Transactions on Medical Imaging.

[16]  J. Giaconi,et al.  Pearls of glaucoma management , 2010 .