The Next Generation of ALI Genetics: Insights into Pathophysiology

[1]  Alex Sazonovs,et al.  Whole Genome Sequencing , 2020, Definitions.

[2]  C. Goss,et al.  Genetic variation in the FAS gene and associations with acute lung injury. , 2011, American journal of respiratory and critical care medicine.

[3]  Mousheng Xu,et al.  Mapping of numerous disease-associated expression polymorphisms in primary peripheral blood CD4+ lymphocytes. , 2010, Human molecular genetics.

[4]  D. Prows,et al.  Functional genomics of chlorine-induced acute lung injury in mice. , 2010, Proceedings of the American Thoracic Society.

[5]  F. Collins,et al.  Genomic medicine--an updated primer. , 2010, The New England journal of medicine.

[6]  H. Hakonarson,et al.  IL1RN Polymorphism Is Associated With Lower Risk Of Acute Lung Injury In Two Separate At-Risk Populations , 2010, ATS 2010.

[7]  M. King,et al.  Genetic Heterogeneity in Human Disease , 2010, Cell.

[8]  P. Shannon,et al.  Exome sequencing identifies the cause of a Mendelian disorder , 2009, Nature Genetics.

[9]  Judy H. Cho,et al.  Finding the missing heritability of complex diseases , 2009, Nature.

[10]  Joseph K. Pickrell,et al.  The Role of Geography in Human Adaptation , 2009, PLoS genetics.

[11]  M. Matthay,et al.  4G/5G Polymorphism of Plasminogen Activator Inhibitor -1 Gene Is Associated with Mortality in Intensive Care Unit Patients with Severe Pneumonia , 2009, Anesthesiology.

[12]  K. Barnes,et al.  Recent advances in genetic predisposition to clinical acute lung injury. , 2009, American journal of physiology. Lung cellular and molecular physiology.

[13]  M. Gong.  Gene association studies in acute lung injury: replication and future direction. , 2009, American journal of physiology. Lung cellular and molecular physiology.

[14]  E. Xing,et al.  Discovery of the gene signature for acute lung injury in patients with sepsis. , 2009, Physiological genomics.

[15]  K. Frazer,et al.  Human genetic variation and its contribution to complex traits , 2009, Nature Reviews Genetics.

[16]  A. Localio,et al.  Large Scale Genotyping in an African American Trauma Population Identifies Angiopoietin-2 Variants Associated with ALI. , 2009, ATS 2009.

[17]  D. Christiani,et al.  Genetic variants in the angiopoietin-2 gene are associated with increased risk of ARDS , 2009, Intensive Care Medicine.

[18]  L. Liang,et al.  Mapping complex disease traits with global gene expression , 2009, Nature Reviews Genetics.

[19]  J. Hokanson,et al.  Extracellular superoxide dismutase haplotypes are associated with acute lung injury and mortality. , 2009, American journal of respiratory and critical care medicine.

[20]  J. Christie,et al.  Extracellular superoxide dismutase haplotypes and acute lung injury: reading into the genome to understand mortality? , 2009, American journal of respiratory and critical care medicine.

[21]  Mark I. McCarthy,et al.  Concept, Design and Implementation of a Cardiovascular Gene-Centric 50 K SNP Array for Large-Scale Genomic Association Studies , 2008, PloS one.

[22]  J. Villar,et al.  A quality assessment of genetic association studies supporting susceptibility and outcome in acute lung injury , 2008, Critical care.

[23]  M. Rieder,et al.  Toll-like receptor 1 polymorphisms affect innate immune responses and outcomes in sepsis. , 2008, American journal of respiratory and critical care medicine.

[24]  Mingyao Li,et al.  Variation in the myosin light chain kinase gene is associated with development of acute lung injury after major trauma* , 2008, Critical care medicine.

[25]  Shwu-Fan Ma,et al.  IL6 gene-wide haplotype is associated with susceptibility to acute lung injury. , 2008, Translational research : the journal of laboratory and clinical medicine.

[26]  M. McCarthy,et al.  Genome-wide association studies for complex traits: consensus, uncertainty and challenges , 2008, Nature Reviews Genetics.

[27]  C. Greenwood,et al.  Differential gene profiling in acute lung injury identifies injury-specific gene expression* , 2008, Critical care medicine.

[28]  T. Evans,et al.  Pathogenesis of the systemic inflammatory syndrome and acute lung injury: role of iron mobilization and decompartmentalization. , 2008, American journal of physiology. Lung cellular and molecular physiology.

[29]  D. Christiani,et al.  A genome-wide expression analysis in blood identifies pre-elafin as a biomarker in ARDS. , 2008, American journal of respiratory cell and molecular biology.

[30]  Zhaohui S. Qin,et al.  A second generation human haplotype map of over 3.1 million SNPs , 2007, Nature.

[31]  L. Liang,et al.  A genome-wide association study of global gene expression , 2007, Nature Genetics.

[32]  P. Donnelly,et al.  Replicating genotype–phenotype associations , 2007, Nature.

[33]  Paige L. Williams,et al.  Polymorphisms in the mannose binding lectin‐2 gene and acute respiratory distress syndrome* , 2007, Critical care medicine.

[34]  Johanna M Seddon,et al.  Common variation in three genes, including a noncoding variant in CFH, strongly influences risk of age-related macular degeneration , 2006, Nature Genetics.

[35]  D. Christiani,et al.  Interleukin-10 polymorphism in position -1082 and acute respiratory distress syndrome , 2006, European Respiratory Journal.

[36]  A. Medford,et al.  Vascular endothelial growth factor gene polymorphism and acute respiratory distress syndrome , 2005, Thorax.

[37]  T. Standiford,et al.  Pre-B-cell colony-enhancing factor as a potential novel biomarker in acute lung injury. , 2005, American journal of respiratory and critical care medicine.

[38]  K. Walley,et al.  The association of interleukin 6 haplotype clades with mortality in critically ill adults. , 2005, Archives of internal medicine.

[39]  John Quackenbush,et al.  Orthologous gene-expression profiling in multi-species models: search for candidate genes , 2004, Genome Biology.

[40]  S. Humphries,et al.  Angiotensin converting enzyme insertion/deletion polymorphism is associated with susceptibility and outcome in acute respiratory distress syndrome. , 2002, American journal of respiratory and critical care medicine.

[41]  D. Nickerson,et al.  Variation is the spice of life , 2001, Nature Genetics.

[42]  V. Chinchilli,et al.  Polymorphisms of human SP‐A, SP‐B, and SP‐D genes: association of SP‐B Thr131Ile with ARDS , 2000, Clinical genetics.

[43]  M. Ashburner,et al.  Gene Ontology: tool for the unification of biology , 2000, Nature Genetics.

[44]  G. Zimmerman,et al.  The acute respiratory distress syndrome. , 1996, The Journal of clinical investigation.

[45]  A. W. den Hartog,et al.  Open Access Research , 2022 .

[46]  Brad T. Sherman,et al.  Systematic and integrative analysis of large gene lists using DAVID bioinformatics resources , 2008, Nature Protocols.

[47]  L. Cardon,et al.  Designing candidate gene and genome-wide case–control association studies , 2007, Nature Protocols.

[48]  N. Meyer,et al.  Wading into the genomic pool to unravel acute lung injury genetics. , 2007, Proceedings of the American Thoracic Society.

[49]  Susumu Goto,et al.  KEGG: Kyoto Encyclopedia of Genes and Genomes , 2000, Nucleic Acids Res..