Influence of ESR1 L and FSHB genes on litter size in Czech Large White sows (short communication)

Abstract. The effects of the candidate genes for reproduction, the estrogen receptor gene ( ESR1 ) and the follicle-stimulating hormone beta subunit gene ( FSHB ), on the performance of Large White sows in the three different herds have been examined. A total number of 271 sows (in case of the ESR1 gene) and 171 sows (in case of the FSHB gene) were genotyped with PCR-RFLP method and analysed to determine whether polymorphisms of the genes influence the efficiency of Large White sows. The influence of these genes in the first, the first to the fourth and the second to the fourth litters was investigated. To discover the genes' associations with reproduction traits, mixed linear models were used. The influence of ESR1 and FSHB genes was not very conclusive in the studied populations. The influence of these genes was different depending on the herd, in which the sows were bred or on the set of analyzed litters.

[1]  J. Wolf,et al.  Impact of the ESR gene on litter size and production traits in Czech Large White pigs. , 2004, Animal genetics.

[2]  L. Alexander,et al.  Mapping the β subunit of follicle stimulating hormone (FSHB) in the porcine genome , 1994, Mammalian Genome.

[3]  K. M. Irvin,et al.  Examination of the relationship between the estrogen receptor gene and reproductive traits in swine. , 2002, Journal of animal science.

[4]  B. Katzenellenbogen,et al.  Molecular Cloning of Porcine Estrogen Receptor-β Complementary DNAs and Developmental Expression in Periimplantation Embryos1 , 2002, Biology of reproduction.

[5]  D. Pomp,et al.  Candidate gene analysis for loci affecting litter size and ovulation rate in swine. , 2001, Journal of animal science.

[6]  K. Grijspeerdt,et al.  ASSOCIATION STUDY OF AN AVAI AND PVUII POLYMORPHISM AT THE PORCINE ESTROGEN RECEPTOR (ESR) GENE, WITH LITTER SIZE , 1999 .

[7]  J. Krieter,et al.  Influence of the genome region surrounding the estrogen receptor (ESR) gene on litter size in a German Landrace population , 1999 .

[8]  C. Tuggle,et al.  Effect of the estrogen receptor locus on reproduction and production traits in four commercial pig lines. , 1997, Journal of animal science.

[9]  M. Yerle,et al.  PCR amplification and physical localization of the genes for pig FSHB and LHB. , 1995, Cytogenetics and cell genetics.

[10]  G. S. Greenwald,et al.  Hypophysectomy of the cyclic mouse. II. Effects of follicle-stimulating hormone (FSH) and luteinizing hormone on folliculogenesis, FSH and human chorionic gonadotropin receptors, and steroidogenesis. , 1993, Biology of reproduction.

[11]  P. Pearson,et al.  PvuII polymorphisms at the porcine oestrogen receptor locus (ESR). , 2009, Animal genetics.