Glycinergic Transmission: Physiological, Developmental and Pathological Implications

The last few years have seen remarkable developments in our understanding of the physiology, pharmacology and genetics of inhibitory glycinergic synapses. In part, this has been due to the development of new resources such as specific antisera recognizing glycine receptor (GlyR) and transporter (GlyT) subtypes, but also the characterization of new mouse, zebrafish and bovine genetic models of glycinergic dysfunction. What is also evident is the high quality and impact of the research conducted in this field. This is reflected in the reviews and research articles in this Special Issue entitled “Glycinergic transmission: physiological, developmental and pathological implications”.

[1]  M. Saha,et al.  The Specification of Glycinergic Neurons and the Role of Glycinergic Transmission in Development , 2010, Front. Mol. Neurosci..

[2]  Richard L. M. Faull,et al.  Localization of Glycine Receptors in the Human Forebrain, Brainstem, and Cervical Spinal Cord: An Immunohistochemical Review , 2009, Front. Mol. Neurosci..

[3]  A. Triller,et al.  Cellular Transport and Membrane Dynamics of the Glycine Receptor , 2009, Front. Mol. Neurosci..

[4]  A. Dickenson,et al.  A Selective Role for α3 Subunit Glycine Receptors in Inflammatory Pain , 2009, Front. Mol. Neurosci..

[5]  J. Rigo,et al.  Glycine and Glycine Receptor Signalling in Non-Neuronal Cells , 2009, Front. Mol. Neurosci..

[6]  R. Callister,et al.  Early History of Glycine Receptor Biology in Mammalian Spinal Cord Circuits , 2010, Front. Mol. Neurosci..

[7]  J. Dallman,et al.  Glycinergic Synapse Development, Plasticity, and Homeostasis in Zebrafish , 2009, Front. Mol. Neurosci..

[8]  Jochen C. Meier,et al.  Glycine Receptors Caught between Genome and Proteome – Functional Implications of RNA Editing and Splicing , 2009, Front. Mol. Neurosci..

[9]  R. Thomas,et al.  Frontiers in Molecular Neuroscience Molecular Neuroscience Review Article , 2022 .

[10]  J. R. Geiger,et al.  Potentiation of Glycine-Gated NR1/NR3A NMDA Receptors Relieves Ca2+-Dependent Outward Rectification , 2009, Front. Mol. Neurosci..

[11]  Hiromi Hirata,et al.  Defective Glycinergic Synaptic Transmission in Zebrafish Motility Mutants , 2009, Front. Mol. Neurosci..

[12]  Robiul Islam,et al.  High Throughput Techniques for Discovering New Glycine Receptor Modulators and their Binding Sites , 2009, Front. Mol. Neurosci..