Quantitative assessment of the anterior segment using ultrasound biomicroscopy.

The development of ocular imaging devices has progressed rapidly during the past 10 years. Ultrasound biomicroscopy has revolutionized the evaluation of the anterior segment of the eye. The qualitative information gathered using this technology has contributed to our understanding of the pathophysiology of angle-closure glaucoma, pigmentary glaucoma, and a variety of other anterior segment disorders. However, the area of quantitative analysis of ultrasound biomicroscopic images remains largely to be developed. This review describes the role of ultrasound biomicroscopy in the measurement of the anatomic structures and their configurations within the anterior segment. Included are previously published and established methods as well as methods in their early stages of development. Application of quantitative image analysis techniques should yield significant information about mechanisms of appositional angle closure, dynamic functions of the iris, accommodation, and presbyopia.

[1]  S. F. Urbak.  Ultrasound biomicroscopy. III. Accuracy and agreement of measurements. , 1999, Acta ophthalmologica Scandinavica.

[2]  C Tello,et al.  Measurement of ultrasound biomicroscopy images: intraobserver and interobserver reliability. , 1994, Investigative ophthalmology & visual science.

[3]  R. Ritch,et al.  Ultrasound biomicroscopy in pigment dispersion syndrome. , 1994, Ophthalmology.

[4]  R. Ritch,et al.  Reduced trabecular meshwork height in juvenile primary open-angle glaucoma. , 1996, Archives of ophthalmology.

[5]  E. Chihara,et al.  Age and Increased Incidence of “Forward Bowing” of the Iris in Normal Eyes , 1998, Journal of glaucoma.

[6]  S. Cronemberger,et al.  Ultrasound biomicroscopic imaging of posterior chamber phakic intraocular lens. , 1998, Journal of refractive surgery.

[7]  S. Kishi,et al.  Serous detachment of the ciliary body in Harada disease. , 1998, American journal of ophthalmology.

[8]  S F Urbak,et al.  Ultrasound biomicroscopy. I. Precision of measurements. , 1998, Acta ophthalmologica Scandinavica.

[9]  D. A. Christopher,et al.  High-frequency Doppler ultrasound examination of blood flow in the anterior segment of the eye. , 1998, American journal of ophthalmology.

[10]  D J Coleman,et al.  The shape of Bowman's layer in the human cornea. , 1998, Journal of refractive surgery.

[11]  G. Marchini,et al.  Ultrasound biomicroscopy and corneal endothelium in Nd:YAG-laser iridotomy. , 1995, Ophthalmic surgery and lasers.

[12]  D J Coleman,et al.  Improved system for sonographic imaging and biometry of the cornea , 1997, Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine.

[13]  R Ritch,et al.  Ultrasound biomicroscopy dark room provocative testing: a quantitative method for estimating anterior chamber angle width. , 1999, Japanese journal of ophthalmology.

[14]  G. Marchini,et al.  Ultrasound biomicroscopic and conventional ultrasonographic study of ocular dimensions in primary angle-closure glaucoma. , 1998, Ophthalmology.

[15]  R. Ritch,et al.  Increase in iris-lens contact after laser iridotomy for pupillary block angle closure. , 1996, American journal of ophthalmology.

[16]  A. Mermoud,et al.  An ultrasound biomicroscopic study of eyes after deep sclerectomy with collagen implant. , 1998, Ophthalmology.

[17]  R. Silverman,et al.  Advances in ophthalmic ultrasound. , 1998, Radiologic clinics of North America.

[18]  J. K. Pedersen,et al.  Ultrasound biomicroscopy. II. Intraobserver and interobserver reproducibility of measurements. , 1998, Acta ophthalmologica Scandinavica.

[19]  S. F. Urbak.  Ultrasound biomicroscopical study of the irido-corneal angle in dominant juvenile open-angle glaucoma, in POAG, and in normal eyes. , 1999, Acta ophthalmologica Scandinavica.

[20]  D J Coleman,et al.  Imaging and spectrum analysis of contrast agents in the in vivo rabbit eye using very-high-frequency ultrasound. , 1998, Ultrasound in medicine & biology.

[21]  J. Kiryu,et al.  Pilocarpine induces an increase in the anterior chamber angular width in eyes with narrow angles , 1999, The British journal of ophthalmology.

[22]  L. Pierro,et al.  High-Frequency Ultrasound Biomicroscopy versus Ultrasound and Optical Pachymetry for the Measurement of Corneal Thickness , 1998, Ophthalmologica.

[23]  T. Avitabile,et al.  Ultrasound-Biomicroscopic Evaluation of Filtering Blebs after Laser Suture Lysis Trabeculectomy , 1998, Ophthalmologica.

[24]  R. Silverman,et al.  High-resolution ultrasonic imaging of blood flow in the anterior segment of the eye. , 1999, Investigative ophthalmology & visual science.

[25]  R. Ritch,et al.  Location of the iris insertion in pigment dispersion syndrome. , 1996, Ophthalmology.

[26]  H. Ishikawa,et al.  Anterior segment implantation cysts. Ultrasound biomicroscopy with histopathologic correlation. , 1998, Archives of ophthalmology.

[27]  Y. Kitazawa,et al.  An ultrasound biomicroscopic study of filtering blebs after mitomycin C trabeculectomy. , 1995, Ophthalmology.

[28]  T. Avitabile,et al.  Keratoconus Staging with Ultrasound Biomicroscopy , 1998, Ophthalmologica.

[29]  A. Crichton,et al.  The use of ultrasound biomicroscopy following trabeculectomy. , 1996, Canadian journal of ophthalmology. Journal canadien d'ophtalmologie.

[30]  D J Coleman,et al.  Three-dimensional ultrasound imaging. Clinical applications. , 1998, Ophthalmology.

[31]  R. Ritch,et al.  Ciliary body enlargement and cyst formation in uveitis. , 1996, The British journal of ophthalmology.

[32]  F. Lizzi,et al.  Correlation of high-frequency ultrasound backscatter with tumor microstructure in iris melanoma. , 1998, Ophthalmology.

[33]  F. Foster,et al.  Ultrasound biomicroscopic imaging of the anterior aspect of peripheral choroidal melanomas. , 1997, American journal of ophthalmology.

[34]  J. Kiryu,et al.  Ultrasound biomicroscopic measurement of development of anterior chamber angle , 1999, The British journal of ophthalmology.

[35]  F. Foster,et al.  Subsurface ultrasound microscopic imaging of the intact eye. , 1990, Ophthalmology.

[36]  G. Marchini,et al.  Effects of 0.2% brimonidine on ocular anterior structures. , 1999, Journal of ocular pharmacology and therapeutics : the official journal of the Association for Ocular Pharmacology and Therapeutics.

[37]  R. Silverman,et al.  Very high-frequency ultrasound corneal analysis identifies anatomic correlates of optical complications of lamellar refractive surgery: anatomic diagnosis in lamellar surgery. , 1999, Ophthalmology.

[38]  F. Foster,et al.  Clinical use of ultrasound biomicroscopy. , 1991, Ophthalmology.