Invasive breast cancer in ectopic axillary breast tissue — case report

Breast cancer is the most commonly diagnosed malignancy in women in Poland. Rare, unusual forms of breast cancer remain a diagnostic problem. The incidence of ectopic breast glandular tissue in the general population varies between 0.4 and 6%. The same abnormalities and diseases as in the anatomical mammary gland may develop in this tissue. Breast cancer may develop as well. We present the case of a 36-year-old woman, who went to the doctor because of a nodule in the right armpit presented for 2 years. The patient was referred to a surgeon with suspicion of an epidermal cyst. The lesion was surgically removed and in the histopathological examination, the diagnose was: invasive breast cancer in ectopic glandular tissue. After imaging diagnostics, discussion of a multidisciplinary diagnostic and therapeutic team, the patient was offered a surgical procedure - widening of the excision margins to obtain oncological completeness and axillary lymphadenectomy. After the surgery, due to the results of the histopathological examination, complementary systemic treatment (chemo- and hormone therapy) and radiotherapy were used. Doctors often do not consider the possibility of primary breast cancer occurring elsewhere than in the breast. Breast imaging does not always make it possible to diagnose the disease, and doctors performing and interpreting these tests often do not include primary armpit cancer in the differential diagnosis. This can cause a delay in diagnosis and worsen the prognosis.

[1]  O. Olutoye,et al.  Breast Embryology, Anatomy, and Physiology , 2018 .

[2]  Y. Atef,et al.  Axillary Masse, is it an Ectopic Mammary Gland? , 2016 .

[3]  Yong Zhang,et al.  Diagnosis and treatment of accessory breast cancer in 11 patients. , 2015, Oncology letters.

[4]  E. Traverso,et al.  Ectopic Breast Cancer: Case Report and Review of the Literature , 2013, Aesthetic Plastic Surgery.

[5]  J. Bart,et al.  Approach and management of primary ectopic breast carcinoma in the axilla: where are we? A comprehensive historical literature review. , 2011, Journal of plastic, reconstructive & aesthetic surgery : JPRAS.

[6]  W. Tjalma,et al.  The management of ectopic breast cancer--case report. , 2006, European journal of gynaecological oncology.

[7]  P. Veronesi,et al.  Sentinel node biopsy in ectopic breast cancer. , 2003, Nuclear medicine communications.

[8]  C. Yiangou,et al.  The use of sentinel node biopsy in the treatment of cancer of an accessory breast. , 2003, Breast.

[9]  J. Verhaeghe,et al.  Breast carcinoma located in ectopic breast tissue: a case report and review of the literature. , 1998, Oncology reports.

[10]  V. Velanovich,et al.  Ectopic breast tissue, supernumerary breasts, and supernumerary nipples. , 1995, Southern medical journal.

[11]  D. Evans,et al.  Carcinoma of the axillary breast , 1995, Journal of surgical oncology.

[12]  S. Evans,et al.  Ectopic breast cancer: case report and literature review. , 1994, Surgical oncology.

[13]  K. Sugimachi,et al.  [A case of carcinoma originating from accessory breast tissue of the axilla]. , 1984, Gan no rinsho. Japan journal of cancer clinics.

[14]  H. D. Cogswell,et al.  Carcinoma of aberrant breast of the axilla. , 1961, The American surgeon.