论文信息 - 2′‐Hydroxy‐3′‐(morpholin‐4‐yl‐methyl)‐4′,6′‐dimethoxy‐2‐chloro‐chalcone

2′‐Hydroxy‐3′‐(morpholin‐4‐yl‐methyl)‐4′,6′‐dimethoxy‐2‐chloro‐chalcone

In the title compound, C22H24ClNO5, the carbonyl group is in an s-cis configuration with respect to the olefinic double bond. In the crystal structure, there are weak π-stacking interactions but there are no significant intermolecular hydrogen bonds.

Yongzhou Hu | Tao Liu | Zhongmiao Xu

[1] N. Davidson,et al. Design, synthesis, and evaluation of novel boronic-chalcone derivatives as antitumor agents. , 2003, Journal of medicinal chemistry.

[2] C. Pouget,et al. Flavonoids: structural requirements for antiproliferative activity on breast cancer cells. , 2001, Bioorganic & medicinal chemistry letters.

2′‐Hydr­oxy‐3′‐(morpholin‐4‐yl‐meth­yl)‐4′,6′‐dimeth­oxy‐2‐chloro‐chalcone

2′‐Hydroxy‐3′‐(morpholin‐4‐yl‐methyl)‐4′,6′‐dimethoxy‐2‐chloro‐chalcone