Transforming Growth Factor-β: Biology and Clinical Relevance

TGF-β signaling pathway’s elucidation has shown it to bevery complex with multiple levels of regulation, involved inmany processes, including development, wound healing,fibrosis, carcinogenesis, angiogenesis, and immunity to namea few. Herein, we outline some of the clinically relevantaspects of this intriguing, and rapidly progressing field.

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