Mfold web server for nucleic acid folding and hybridization prediction
Abstract:The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and 'energy dot plots', are available for the folding of single sequences. A variety of 'bulk' servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'.
摘要:缩写名称MFold Web服务器描述了万维网(WWW)上可用于预测单链核酸二级结构的许多密切相关的软件应用程序。该网络服务器的目标是为广大科学界提供使用RNA和DNA折叠和杂交软件的便捷途径。通过使用普遍可用的网络图形用户界面(图形用户界面),服务器绕过了该软件的可移植性问题。具有或不具有可靠性信息的结构图、单链频率图和‘能量点图’形式的详细输出可用于单序列的折叠。各种各样的“批量”服务器提供的信息较少,但时间更短,一次最多可以处理数百个序列。MFold Web服务器的门户是http://www.bioinfo.rpi.edu/applications/mfold.此URL将被称为‘MFOLDROOT’。
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