Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement
Economic evaluations of health interventions pose a particular challenge for reporting. There is also a need to consolidate and update existing guidelines and promote their use in a user friendly manner. The Consolidated Health Economic Evaluation Reporting Standards (CHEERS) statement is an attempt to consolidate and update previous health economic evaluation guidelines efforts into one current, useful reporting guidance. The primary audiences for the CHEERS statement are researchers reporting economic evaluations and the editors and peer reviewers assessing them for publication. The need for new reporting guidance was identified by a survey of medical editors. A list of possible items based on a systematic review was created. A two round, modified Delphi panel consisting of representatives from academia, clinical practice, industry, government, and the editorial community was conducted. Out of 44 candidate items, 24 items and accompanying recommendations were developed. The recommendations are contained in a user friendly, 24 item checklist. A copy of the statement, accompanying checklist, and this report can be found on the ISPOR Health Economic Evaluations Publication Guidelines Task Force website (www.ispor.org/TaskForces/EconomicPubGuidelines.asp). We hope CHEERS will lead to better reporting, and ultimately, better health decisions. To facilitate dissemination and uptake, the CHEERS statement is being co-published across 10 health economics and medical journals. We encourage other journals and groups, to endorse CHEERS. The author team plans to review the checklist for an update in five years.
Appraising and Amending Theories: The Strategy of Lakatosian Defense and Two Principles that Warrant It
In social science, everything is somewhat correlated with everything (“crud factor”), so whether H0 is refuted depends solely on statistical power. In psychology, the directional counternull of interest, H*, is not equivalent to the substantive theory T, there being many plausible alternative explanations of a mere directional trend (weak use of significance tests). Testing against a predicted point value (the strong use of significant tests) can discorroborate T by refuting H*. If used thus to abandon T forthwith, it is too strong, not allowing for theoretical verisimilitude as distinguished from truth. Defense and amendment of an apparently falsified T are appropriate strategies only when T has accumulated a good track record (“money in the bank”) by making successful or near-miss predictions of low prior probability (Salmon’s “damn strange coincidences”). Two rough indexes are proposed for numerifying the track record, by considering jointly how intolerant (risky) and how close (accurate) are its predictions.
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