Mfold web server for nucleic acid folding and hybridization prediction
The abbreviated name, 'mfold web server', describes a number of closely related software applications available on the World Wide Web (WWW) for the prediction of the secondary structure of single stranded nucleic acids. The objective of this web server is to provide easy access to RNA and DNA folding and hybridization software to the scientific community at large. By making use of universally available web GUIs (Graphical User Interfaces), the server circumvents the problem of portability of this software. Detailed output, in the form of structure plots with or without reliability information, single strand frequency plots and 'energy dot plots', are available for the folding of single sequences. A variety of 'bulk' servers give less information, but in a shorter time and for up to hundreds of sequences at once. The portal for the mfold web server is http://www.bioinfo.rpi.edu/applications/mfold. This URL will be referred to as 'MFOLDROOT'.
ExPASy: the proteomics server for in-depth protein knowledge and analysis
The ExPASy (the Expert Protein Analysis System) World Wide Web server (http://www.expasy.org), is provided as a service to the life science community by a multidisciplinary team at the Swiss Institute of Bioinformatics (SIB). It provides access to a variety of databases and analytical tools dedicated to proteins and proteomics. ExPASy databases include SWISS-PROT and TrEMBL, SWISS-2DPAGE, PROSITE, ENZYME and the SWISS-MODEL repository. Analysis tools are available for specific tasks relevant to proteomics, similarity searches, pattern and profile searches, post-translational modification prediction, topology prediction, primary, secondary and tertiary structure analysis and sequence alignment. These databases and tools are tightly interlinked: a special emphasis is placed on integration of database entries with related resources developed at the SIB and elsewhere, and the proteomics tools have been designed to read the annotations in SWISS-PROT in order to enhance their predictions. ExPASy started to operate in 1993, as the first WWW server in the field of life sciences. In addition to the main site in Switzerland, seven mirror sites in different continents currently serve the user community.
Factors Influencing the Adoption of Internet Banking
A research framework based on the theory of planned behavior (Ajzen 1985) and the diffusion of innovations theory (Rogers 1983) was used to identify the attitudinal, social and perceived behavioral control factors that would influence the adoption of Internet banking. An online questionnaire was designed on the World Wide Web (WWW). Respondents participated through extensive personalized email invitations as well as postings to newsgroups and hyperlinks from selected Web sites.
Web server workload characterization: the search for invariants
The phenomenal growth in popularity of the World Wide Web (WWW, or the Web) has made WWW traffic the largest contributor to packet and byte traffic on the NSFNET backbone. This growth has triggered recent research aimed at reducing the volume of network traffic produced by Web clients and servers, by using caching, and reducing the latency for WWW users, by using improved protocols for Web interaction.Fundamental to the goal of improving WWW performance is an understanding of WWW workloads. This paper presents a workload characterization study for Internet Web servers. Six different data sets are used in this study: three from academic (i.e., university) environments, two from scientific research organizations, and one from a commercial Internet provider. These data sets represent three different orders of magnitude in server activity, and two different orders of magnitude in time duration, ranging from one week of activity to one year of activity.Throughout the study, emphasis is placed on finding workload invariants: observations that apply across all the data sets studied. Ten invariants are identified. These invariants are deemed important since they (potentially) represent universal truths for all Internet Web servers. The paper concludes with a discussion of caching and performance issues, using the invariants to suggest performance enhancements that seem most promising for Internet Web servers.
Performance Guarantees for Web Server End-Systems: A Control-Theoretical Approach
The Internet is undergoing substantial changes from a communication and browsing infrastructure to a medium for conducting business and marketing a myriad of services. The World Wide Web provides a uniform and widely-accepted application interface used by these services to reach multitudes of clients. These changes place the Web server at the center of a gradually emerging e-service infrastructure with increasing requirements for service quality and reliability guarantees in an unpredictable and highly-dynamic environment. This paper describes performance control of a Web server using classical feedback control theory. We use feedback control theory to achieve overload protection, performance guarantees, and service differentiation in the presence of load unpredictability. We show that feedback control theory offers a promising analytic foundation for providing service differentiation and performance guarantees. We demonstrate how a general Web server may be modeled for purposes of performance control, present the equivalents of sensors and actuators, formulate a simple feedback loop, describe how it can leverage on real-time scheduling and feedback-control theories to achieve per-class response-time and throughput guarantees, and evaluate the efficacy of the scheme on an experimental testbed using the most popular Web server, Apache. Experimental results indicate that control-theoretic techniques offer a sound way of achieving desired performance in performance-critical Internet applications. Our QoS (Quality-of-Service) management solutions can be implemented either in middleware that is transparent to the server, or as a library called by server code.
information system management system cloud computing decision making information technology world wide web life cycle hidden markov model markov model wide web world wide empirical study sustainable development literature review factors affecting life cycle assessment developing country web server parallel algorithm factors influencing cycle assessment electronic commerce technology acceptance model environmental management protein structure user authentication empirical investigation technology acceptance amino acid independent set cloud computing service integrated model protein sequence protein data bank corporate governance nucleic acid set problem sustainability assessment technology adoption environmental management system mobile commerce environmental sustainability internet banking life cycle costing fast parallel maximum independent set mobile banking electronic busines independent set problem maximum independent maximal independent set business network perceived risk cloud computing adoption maximal independent internet web computing adoption workload characterization adoption model sustainability indicator fast parallel algorithm target prediction sustainability issue life cycle sustainability performance outcome top management support adoption of mobile innovation adoption corporate sustainability system adoption information technology adoption adoption decision influencing the adoption cycle sustainability tam model weighted independent set technology adoption model adoption rate sustainability reporting set packing amino acid substitution adoption behavior weighted independent commerce adoption consumer adoption adoption of internet generalized hidden markov sustainability practice banking adoption weighted set subset problem acid substitution e-business adoption product adoption perceived behavioral control natural capital mirna target prediction electronic commerce adoption mobile banking adoption adoption research toe framework ecological sustainability agricultural sustainability independent sequence internet web server technology adoption research review [publication type] united state