Peter Van Loo

发表

Allele-specific multi-sample copy number segmentation in ASCAT.

Florian Markowetz, Edith M Ross, Kerstin Haase, 2020, Bioinformatics.

A community effort to create standards for evaluating tumor subclonal reconstruction

Nathan M. Wilson, Ville Mustonen, Salem Malikic, 2019, Nature Biotechnology.

Butler enables rapid cloud-based analysis of thousands of human genomes

Robert L. Grossman, Oliver Hofmann, Roland Eils, 2020, Nature Biotechnology.

Neutral tumor evolution?

Benjamin J. Raphael, Florian Markowetz, Iñigo Martincorena, 2017, Nature Genetics.

The genetic heterogeneity and mutational burden of engineered melanomas in zebrafish models

Yves Moreau, Jeroen de Ridder, Keiran Raine, 2013, Genome Biology.

Principles of Reconstructing the Subclonal Architecture of Cancers.

David C Wedge, Peter Van Loo, D. Wedge, 2017, Cold Spring Harbor perspectives in medicine.

Phylogenetic ctDNA analysis depicts early stage lung cancer evolution

Ashwini Naik, Allan Hackshaw, Zoltan Szallasi, 2017, Nature.

LRP1B deletion in high-grade serous ovarian cancers is associated with acquired chemotherapy resistance to liposomal doxorubicin.

Joshy George, Peter Campbell, David D L Bowtell, 2012, Cancer research.

Deterministic Evolutionary Trajectories Influence Primary Tumor Growth: TRACERx Renal

Zoltan Szallasi, Ashish Chandra, Adam Huffman, 2018, Cell.

Mutational signatures of ionizing radiation in second malignancies

Christophe Badie, Rebecca Shepherd, David Jones, 2016, Nature Communications.

Pan-cancer analysis of homozygous deletions in primary tumours uncovers rare tumour suppressors

Yves Moreau, Kevin P. White, Peter J. Campbell, 2017, Nature Communications.

ModuleMiner - improved computational detection of cis-regulatory modules: are there different modes of gene regulation in embryonic development and adult tissues?

Yves Moreau, Stein Aerts, Bart De Moor, 2008, Genome Biology.

Combined hereditary and somatic mutations of replication error repair genes result in rapid onset of ultra-hypermutated cancers

Roland Arnold, Richard G Grundy, Daniele Merico, 2015, Nature Genetics.

Polysomy 17 in breast cancer: clinicopathologic significance and impact on HER-2 testing.

Patrick Neven, Peter Van Loo, P. Neven, 2008, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

Subclonal diversification of primary breast cancer revealed by multiregion sequencing

Andrew Menzies, Keiran Raine, Young Seok Ju, 2015, Nature Medicine.

Inferring structural variant cancer cell fraction

Roland Eils, Yuan Ji, Jan Schröder, 2020, Nature Communications.

Recurrent mutation of IGF signalling genes and distinct patterns of genomic rearrangement in osteosarcoma

Daniel Baumhoer, Inigo Martincorena, Roberto Tirabosco, 2017, Nature Communications.

Constitutional and somatic rearrangement of chromosome 21 in acute lymphoblastic leukaemia

Peter J. Campbell, Michael R. Stratton, Ben Robinson, 2014, Nature.

Analysis of the Genetic Phylogeny of Multifocal Prostate Cancer Identifies Multiple Independent Clonal Expansions in Neoplastic and Morphologically Normal Prostate Tissue

Andrew Menzies, Keiran Raine, Rosalind Eeles, 2015, Nature Genetics.

Integrated molecular profiles of invasive breast tumors and ductal carcinoma in situ (DCIS) reveal differential vascular and interleukin signaling

David Haussler, Olga G. Troyanskaya, Charles J. Vaske, 2011, Proceedings of the National Academy of Sciences.

Origins and functional consequences of somatic mitochondrial DNA mutations in human cancer

Bin Tean Teh, Andrew Menzies, Keiran Raine, 2014, eLife.

Copy number variations alter methylation and parallel IGF2 overexpression in adrenal tumors

David Taieb, Vessela N Kristensen, Anne Barlier, 2015, Endocrine-related cancer.

Differential and limited expression of mutant alleles in multiple myeloma.

Giovanni Parmigiani, David C Wedge, Peter Van Loo, 2014, Blood.

Collaboratively charting the gene-to-phenotype network of human congenital heart defects

Yves Moreau, Marc Gewillig, Roland Barriot, 2010, Genome Medicine.

Extensive transduction of nonrepetitive DNA mediated by L1 retrotransposition in cancer genomes

Andrew Menzies, Adam P. Butler, Jon W. Teague, 2014, Science.

Tracking the origins and drivers of subclonal metastatic expansion in prostate cancer

Michael Kerger, Andrew Lonie, Keval Patel, 2015, Nature Communications.

Spatial heterogeneity of the T cell receptor repertoire reflects the mutational landscape in lung cancer

Peter Schmid, Marcin Skrzypski, Allan Hackshaw, 2019, Nature Medicine.

Translating insights into tumor evolution to clinical practice: promises and challenges

Peter Van Loo, P. Van Loo, M. Fittall, 2019, Genome Medicine.

Single cell analysis of cancer genomes.

Peter Van Loo, Thierry Voet, P. Van Loo, 2014, Current opinion in genetics & development.