Systems Biology of Parkinson's Disease
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[1] J. Parkinson. An Essay on the Shaking Palsy , 2002 .
[2] W. Cannon. The Wisdom of the Body , 1932 .
[3] Norbert Wiener,et al. Cybernetics: Control and Communication in the Animal and the Machine. , 1949 .
[4] A. Hodgkin,et al. Currents carried by sodium and potassium ions through the membrane of the giant axon of Loligo , 1952, The Journal of physiology.
[5] N. Shock,et al. Changes in Cardiac Output with Age , 1955, Circulation.
[6] L. C. Clark,et al. Chronically implanted polarographic electrodes. , 1958, Journal of applied physiology.
[7] K. Fuxe,et al. EVIDENCE FOR THE EXISTENCE OF MONOAMINE-CONTAINING NEURONS IN THE CENTRAL NERVOUS SYSTEM. I. DEMONSTRATION OF MONOAMINES IN THE CELL BODIES OF BRAIN STEM NEURONS. , 1964, Acta physiologica Scandinavica. Supplementum.
[8] E. Newsholme,et al. PROPERTIES OF PHOSPHOFRUCTOKINASE FROM RAT LIVER AND THEIR RELATION TO THE CONTROL OF GLYCOLYSIS AND GLUCONEOGENESIS. , 1965, The Biochemical journal.
[9] Studies of a glassy carbon electrode for brain polarography with observations on the effect of carbonic anhydrase inhibition. , 1965, The Alabama journal of medical sciences.
[10] N. Andén,et al. A quantitative study on the nigro-neostriatal dopamine neuron system in the rat. , 1966, Acta physiologica Scandinavica.
[11] Mihajlo D. Mesarovic,et al. Systems Theory and Biology , 1968 .
[12] M. Savageau. Biochemical systems analysis. II. The steady-state solutions for an n-pool system using a power-law approximation. , 1969, Journal of theoretical biology.
[13] Hugh J. Spencer. Antagonism of cortical excitation of striatal neurons by glutamic acid diethyl ester: Evidence for glutamic acid as an excitatory transmitter in the rat striatum , 1976, Brain Research.
[14] P. Mcgeer,et al. Aging and extrapyramidal function. , 1977, Archives of neurology.
[15] C. W. Ragsdale,et al. Histochemically distinct compartments in the striatum of human, monkeys, and cat demonstrated by acetylthiocholinesterase staining. , 1978, Proceedings of the National Academy of Sciences of the United States of America.
[16] Sanford P. Markey,et al. Chronic parkinsonism secondary to intravenous injection of meperidine analogues , 1979, Psychiatry Research.
[17] B Hess,et al. The glycolytic oscillator. , 1979, The Journal of experimental biology.
[18] Free energy ATP hydrolysis and phosphorylation potential , 1980 .
[19] S. Schultz. Basic principles of membrane transport , 1980 .
[20] M. Herkenham,et al. Interconverting mu and delta forms of the opiate receptor in rat striatal patches. , 1981, Proceedings of the National Academy of Sciences of the United States of America.
[21] M. Herkenham,et al. Mosaic distribution of opiate receptors, parafascicular projections and acetylcholinesterase in rat striatum , 1981, Nature.
[22] D. H. Mellor,et al. Real time , 1981 .
[23] J. Growdon,et al. Effects of oral L-tyrosine administration on CSF tyrosine and homovanillic acid levels in patients with Parkinson's disease. , 1982, Life sciences.
[24] S. Makrides. PROTEIN SYNTHESIS AND DEGRADATION DURING AGING AND SENESCENCE , 1983, Biological reviews of the Cambridge Philosophical Society.
[25] J. Langston,et al. Chronic Parkinsonism in humans due to a product of meperidine-analog synthesis. , 1983, Science.
[26] D. Jacobowitz,et al. A primate model of parkinsonism: selective destruction of dopaminergic neurons in the pars compacta of the substantia nigra by N-methyl-4-phenyl-1,2,3,6-tetrahydropyridine. , 1983, Proceedings of the National Academy of Sciences of the United States of America.
[27] A. Grace,et al. The control of firing pattern in nigral dopamine neurons: burst firing , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[28] C. Gerfen. The neostriatal mosaic: compartmentalization of corticostriatal input and striatonigral output systems , 1984, Nature.
[29] A. Grace,et al. The control of firing pattern in nigral dopamine neurons: single spike firing , 1984, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[30] D. Noble,et al. The surprising heart: a review of recent progress in cardiac electrophysiology. , 1984, The Journal of physiology.
[31] C. Mytilineou,et al. Studies on the mechanism of action of 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). , 1985, Life sciences.
[32] [A model of Parkinson's disease: effect of L-dopa therapy on movement parameters and electromyographic activity in monkeys treated with 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP)]. , 1985, Comptes rendus des seances de la Societe de biologie et de ses filiales.
[33] C. Gerfen. The neostriatal mosaic. I. compartmental organization of projections from the striatum to the substantia nigra in the rat , 1985, The Journal of comparative neurology.
[34] C. Gerfen,et al. The neostriatal mosaic: compartmental distribution of calcium-binding protein and parvalbumin in the basal ganglia of the rat and monkey. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[35] S. Snyder,et al. Parkinsonism-inducing neurotoxin, N-methyl-4-phenyl-1,2,3,6 -tetrahydropyridine: uptake of the metabolite N-methyl-4-phenylpyridine by dopamine neurons explains selective toxicity. , 1985, Proceedings of the National Academy of Sciences of the United States of America.
[36] G. Halliday,et al. Comparative anatomy of the ventromedial mesencephalic tegmentum in the rat, cat, monkey and human , 1986, The Journal of comparative neurology.
[37] J. Donoghue,et al. Neostriatal projections from individual cortical fields conform to histochemically distinct striatal compartments in the rat , 1986, Brain Research.
[38] A. Graybiel,et al. Subdivisions of the dopamine-containing A8-A9-A10 complex identified by their differential mesostriatal innervation of striosomes and extrastriosomal matrix , 1987, Neuroscience.
[39] C. Gerfen,et al. The neostriatal mosaic: III. Biochemical and developmental dissociation of patch-matrix mesostriatal systems , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[40] C. Gerfen,et al. The neostriatal mosaic: II. Patch- and matrix-directed mesostriatal dopaminergic and non-dopaminergic systems , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[41] W. Gibb,et al. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. , 1988, Journal of neurology, neurosurgery, and psychiatry.
[42] J. B. Justice,et al. Modeling the dopaminergic nerve terminal , 1988, Journal of Neuroscience Methods.
[43] A. Graybiel,et al. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease , 1988, Nature.
[44] B. Bunney,et al. Effects of apamin on the discharge properties of putative dopamine-containing neurons in vitro , 1988, Brain Research.
[45] K. S. Bankiewicz,et al. A 6-hydroxydopamine-induced selective parkinsonian rat model , 1989, Brain Research.
[46] Y. Kagawa,et al. Deficiencies in complex I subunits of the respiratory chain in Parkinson's disease. , 1989, Biochemical and biophysical research communications.
[47] J. Parks,et al. Abnormalities of the electron transport chain in idiopathic parkinson's disease , 1989, Annals of neurology.
[48] A. Graybiel,et al. Distinct nigrostriatal projection systems innervate striosomes and matrix in the primate striatum , 1989, Brain Research.
[49] N. Revsbech,et al. An oxygen microsensor with a guard cathode , 1989 .
[50] C. Gerfen. The neostriatal mosaic: striatal patch-matrix organization is related to cortical lamination. , 1989, Science.
[51] C. Marsden,et al. Mitochondrial Complex I Deficiency in Parkinson's Disease , 1990, Lancet.
[52] D. Turnbull,et al. MITOCHONDRIAL FUNCTION IN PARKINSON'S DISEASE , 1989, The Lancet.
[53] T. Archer,et al. MPTP-induced hypoactivity in mice: reversal by L-dopa. , 1990, Pharmacology & toxicology.
[54] P. Mcgeer,et al. Relative sparing in Parkinson's disease of substantia nigra dopamine neurons containing calbindin-D28K , 1990, Brain Research.
[55] C. Marsden,et al. Anatomic and Disease Specificity of NADH CoQ1 Reductase (Complex I) Deficiency in Parkinson's Disease , 1990, Journal of neurochemistry.
[56] A. Hodgkin,et al. A quantitative description of membrane current and its application to conduction and excitation in nerve , 1990 .
[57] M. Muenter,et al. MAO and L-dopa treatment of Parkinson's disease. , 1990, Journal of neural transmission. Supplementum.
[58] J. Barker,et al. Postnatal rat nigrostriatal dopaminergic neurons exhibit five types of potassium conductances. , 1990, Journal of neurophysiology.
[59] K. Shibuki. An electrochemical microprobe for detecting nitric oxide release in brain tissue , 1990, Neuroscience Research.
[60] G. E. Alexander,et al. Basal ganglia-thalamocortical circuits: parallel substrates for motor, oculomotor, "prefrontal" and "limbic" functions. , 1990, Progress in brain research.
[61] G. Sonenshein,et al. Binding of NF-KB-like factors to regulatory sequences of the c-myc gene. , 1990, Current topics in microbiology and immunology.
[62] M. Gourie‐Devi,et al. Treatment of Parkinson's Disease in ‘Ayurveda’ (Ancient Indian System of Medicine): Discussion Paper , 1991, Journal of the Royal Society of Medicine.
[63] A. Lees,et al. Ageing and Parkinson's disease: substantia nigra regional selectivity. , 1991, Brain : a journal of neurology.
[64] Sylvia Charp,et al. Model applications , 1991 .
[65] Babu Subramanyam,et al. MONITORING MOLECULES IN NEUROSCIENCE , 1991 .
[66] T. Malinski,et al. Nitric oxide release from a single cell measured in situ by a porphyrinic-based microsensor , 1992, Nature.
[67] G. Brown,et al. Control of respiration and ATP synthesis in mammalian mitochondria and cells. , 1992, The Biochemical journal.
[68] J. Hughes,et al. Accuracy of clinical diagnosis of idiopathic Parkinson's disease: a clinico-pathological study of 100 cases. , 1992, Journal of neurology, neurosurgery, and psychiatry.
[69] P. Sah,et al. Potassium currents contributing to action potential repolarization and the afterhyperpolarization in rat vagal motoneurons. , 1992, Journal of neurophysiology.
[70] Martyn G. Boutelle,et al. The dialysis electrode—a new method for in vivo monitoring , 1992 .
[71] R. Wightman,et al. Dynamic Observation of Dopamine Autoreceptor Effects in Rat Striatal Slices , 1992, Journal of neurochemistry.
[72] C. Marsden,et al. Brain, skeletal muscle and platelet homogenate mitochondrial function in Parkinson's disease. , 1992, Brain : a journal of neurology.
[73] A. Noma,et al. Turnover rate of the cardiac Na(+)‐Ca2+ exchanger in guinea‐pig ventricular myocytes. , 1993, The Journal of physiology.
[74] Eric L. Schwartz,et al. Computational Neuroscience , 1993, Neuromethods.
[75] Steven W. Johnson,et al. Apamin increases NMDA-induced burst-firing of rat mesencephalic dopamine neurons , 1993, Brain Research.
[76] I. Engberg,et al. Nifedipine‐ and omega‐conotoxin‐sensitive Ca2+ conductances in guinea‐pig substantia nigra pars compacta neurones. , 1993, The Journal of physiology.
[77] G. S. Wilson,et al. Direct measurement of glutamate release in the brain using a dual enzyme-based electrochemical sensor , 1994, Brain Research.
[78] B. Ames,et al. Oxidative damage and mitochondrial decay in aging. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[79] Werner G. Kuhr,et al. Enzyme‐modified microelectrodes for in vivo neurochemical measurements , 1995 .
[80] M. Piercey,et al. Continuous administration decreases and pulsatile administration increases behavioral sensitivity to a novel dopamine D2 agonist (U-91356A) in MPTP-exposed monkeys. , 1995, The Journal of pharmacology and experimental therapeutics.
[81] T. Kaneko,et al. Immunocytochemical localization of μ-opioid receptor in the rat caudate-putamen , 1995, Neuroscience Letters.
[82] D. Johnston,et al. Synaptic activation of voltage-gated channels in the dendrites of hippocampal pyramidal neurons. , 1995, Science.
[83] J. Langston,et al. The Case of the Frozen Addicts , 1995 .
[84] H. Pahl,et al. A novel signal transduction pathway from the endoplasmic reticulum to the nucleus is mediated by transcription factor NF‐kappa B. , 1995, The EMBO journal.
[85] L. Phebus,et al. Measurement of striatal H2O2 by microdialysis following global forebrain ischemia and reperfusion in the rat: correlation with the cytotoxic potential of H2O2 in vitro , 1995, Brain Research.
[86] A. Noma. Ionic mechanisms of the cardiac pacemaker potential. , 1996, Japanese heart journal.
[87] T. Kirkwood,et al. A network theory of ageing: the interactions of defective mitochondria, aberrant proteins, free radicals and scavengers in the ageing process. , 1996, Mutation research.
[88] J. Glowinski,et al. Astrocytes protect neurons from hydrogen peroxide toxicity , 1996, The Journal of neuroscience : the official journal of the Society for Neuroscience.
[89] M. Fillenz,et al. Characterization of carbon paste electrodes in vitro for simultaneous amperometric measurement of changes in oxygen and ascorbic acid concentrations in vivo. , 1996, The Analyst.
[90] D. Oorschot. Total number of neurons in the neostriatal, pallidal, subthalamic, and substantia nigral nuclei of the rat basal ganglia: A stereological study using the cavalieri and optical disector methods , 1996, The Journal of comparative neurology.
[91] A. Salminen,et al. Aging-induced up-regulation of nuclear binding activities of oxidative stress responsive NF-kB transcription factor in mouse cardiac muscle. , 1996, Journal of molecular and cellular cardiology.
[92] N. Marrion,et al. Small-Conductance, Calcium-Activated Potassium Channels from Mammalian Brain , 1996, Science.
[93] A. Salminen,et al. Changes associated with aging and replicative senescence in the regulation of transcription factor nuclear factor-kappa B. , 1996, The Biochemical journal.
[94] R. Heinrich,et al. The Regulation of Cellular Systems , 1996, Springer US.
[95] J. Ruppersberg. Ion Channels in Excitable Membranes , 1996 .
[96] Real time monitoring of biphasic glutamate release using dialysis electrode in rat acute brain ischemia , 1996, Neuroreport.
[97] N. Jaffrezic‐Renault,et al. Brain glucose: voltammetric determination in normal and hyperglycaemic rats using a glucose microsensor , 1997, Neuroreport.
[98] A. Salminen,et al. Age-related changes in the regulation of transcription factor NF-κB in rat brain , 1997, Neuroscience Letters.
[99] H Ujike,et al. VMAT2 knockout mice: heterozygotes display reduced amphetamine-conditioned reward, enhanced amphetamine locomotion, and enhanced MPTP toxicity. , 1997, Proceedings of the National Academy of Sciences of the United States of America.
[100] G. S. Wilson,et al. Rapid Changes in Local Extracellular Rat Brain Glucose Observed with an In Vivo Glucose Sensor , 1997, Journal of neurochemistry.
[101] S. Im,et al. Constitutive activation of NF-kappa B in an animal model of aging. , 1997, International immunology.
[102] A. D. Grey. A proposed refinement of the mitochondrial free radical theory of aging , 1997 .
[103] M. Fillenz,et al. Stimulated release of lactate in freely moving rats is dependent on the uptake of glutamate. , 1997, The Journal of physiology.
[104] G. S. Wilson,et al. A Temporary Local Energy Pool Coupled to Neuronal Activity: Fluctuations of Extracellular Lactate Levels in Rat Brain Monitored with Rapid‐Response Enzyme‐Based Sensor , 1997, Journal of neurochemistry.
[105] Martyn G Boutelle,et al. Measurement of brain tissue oxygen at a carbon paste electrode can serve as an index of increases in regional cerebral blood flow , 1997, Journal of Neuroscience Methods.
[106] D. Gadsby,et al. Voltage dependence of the Na/K pump. , 1997, The Journal of membrane biology.
[107] J S Rakshi,et al. Measuring the rate of progression and estimating the preclinical period of Parkinson’s disease with [18F]dopa PET , 1998, Journal of neurology, neurosurgery, and psychiatry.
[108] A Sorribas,et al. Mathematical models of purine metabolism in man. , 1998, Mathematical biosciences.
[109] M. Chesselet,et al. Toxicity of Dopamine to Striatal Neurons In Vitro and Potentiation of Cell Death by a Mitochondrial Inhibitor , 1998, Journal of neurochemistry.
[110] In vivo voltammetric detection of rat brain lactate with carbon fiber microelectrodes coated with lactate oxidase. , 1998, Analytical chemistry.
[111] C. Nicholson,et al. Extracellular space structure revealed by diffusion analysis , 1998, Trends in Neurosciences.
[112] Martyn G Boutelle,et al. An amperometric glucose-oxidase/poly(o-phenylenediamine) biosensor for monitoring brain extracellular glucose: in vivo characterisation in the striatum of freely-moving rats , 1998, Journal of Neuroscience Methods.
[113] T. Ishii,et al. Mechanism of calcium gating in small-conductance calcium-activated potassium channels , 1998, Nature.
[114] N. Adachi,et al. Measurement of the extracellular H2O2 in the brain by microdialysis. , 1998, Brain research. Brain research protocols.
[115] E. Pothos,et al. D2-Like Dopamine Autoreceptor Activation Reduces Quantal Size in PC12 Cells , 1998, The Journal of Neuroscience.
[116] An improved method for the detection of changes in brain extracellular glutamate levels , 1998, Journal of Neuroscience Methods.
[117] M. Mas,et al. Monitoring brain chemistry in vivo: voltammetric techniques, sensors, and behavioral applications. , 1998, Critical reviews in neurobiology.
[118] Martin Lévesque,et al. The axonal arborization of single nigrostriatal neurons in rats , 1999, Brain Research.
[119] B. Amini,et al. Calcium dynamics underlying pacemaker-like and burst firing oscillations in midbrain dopaminergic neurons: a computational study. , 1999, Journal of neurophysiology.
[120] N. Kulagina,et al. Monitoring glutamate and ascorbate in the extracellular space of brain tissue with electrochemical microsensors. , 1999, Analytical chemistry.
[121] K. Vrana,et al. Cytotoxic and genotoxic potential of dopamine , 1999, Journal of neuroscience research.
[122] R. Hardie,et al. Measuring the rate of progression and estimating the preclinical period of Parkinson’s disease with [18F] dopa PET , 1999, Journal of neurology, neurosurgery, and psychiatry.
[123] P. Chinnery,et al. Relaxed replication of mtDNA: A model with implications for the expression of disease. , 1999, American journal of human genetics.
[124] M. Blaustein,et al. Sodium/calcium exchange: its physiological implications. , 1999, Physiological reviews.
[125] L. Blatter,et al. Dynamic regulation of [Ca2+]i by plasma membrane Ca(2+)-ATPase and Na+/Ca2+ exchange during capacitative Ca2+ entry in bovine vascular endothelial cells. , 1999, Cell calcium.
[126] P. Greengard,et al. Beyond the Dopamine Receptor: Review the DARPP-32/Protein Phosphatase-1 Cascade , 1999 .
[127] H. Pahl. Activators and target genes of Rel/NF-κB transcription factors , 1999, Oncogene.
[128] D. Shelton,et al. Microarray analysis of replicative senescence , 1999, Current Biology.
[129] H. Coller,et al. Cell-by-cell scanning of whole mitochondrial genomes in aged human heart reveals a significant fraction of myocytes with clonally expanded deletions. , 1999, Nucleic acids research.
[130] R. Shulman,et al. Determination of the rate of the glutamate/glutamine cycle in the human brain by in vivo 13C NMR. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[131] Todd B. Sherer,et al. Chronic systemic pesticide exposure reproduces features of Parkinson's disease , 2000, Nature Neuroscience.
[132] N. Holbrook,et al. Oxidants, oxidative stress and the biology of ageing , 2000, Nature.
[133] J. Dichgans,et al. Deficiency of Inducible Nitric Oxide Synthase Protects Against MPTP Toxicity In Vivo , 2000, Journal of neurochemistry.
[134] Albert-László Barabási,et al. Error and attack tolerance of complex networks , 2000, Nature.
[135] G Bernardi,et al. Synaptic transmission in the striatum: from plasticity to neurodegeneration , 2000, Progress in Neurobiology.
[136] Graham C. Goodwin,et al. Control System Design , 2000 .
[137] K. Doya. Complementary roles of basal ganglia and cerebellum in learning and motor control , 2000, Current Opinion in Neurobiology.
[138] C. Wilson,et al. Coupled oscillator model of the dopaminergic neuron of the substantia nigra. , 2000, Journal of neurophysiology.
[139] S. Jazwinski. Metabolic control and ageing. , 2000, Trends in genetics : TIG.
[140] D. Joel,et al. The connections of the dopaminergic system with the striatum in rats and primates: an analysis with respect to the functional and compartmental organization of the striatum , 2000, Neuroscience.
[141] J. Myrheim,et al. A theory for the membrane potential of living cells , 1998, European Biophysics Journal.
[142] P. K. Mohan,et al. Association of l-DOPA with recovery following Ayurveda medication in Parkinson’s disease , 2000, Journal of the Neurological Sciences.
[143] T. Takeuchi,et al. Expression of Ca(2+)-activated K(+) channels, SK3, in the interstitial cells of Cajal in the gastrointestinal tract. , 2001, American journal of physiology. Cell physiology.
[144] G. Gerhardt,et al. Self-referencing ceramic-based multisite microelectrodes for the detection and elimination of interferences from the measurement of L-glutamate and other analytes. , 2001, Analytical chemistry.
[145] A. Parent,et al. The Nigrostriatal Pathway in the Rat: A Single-Axon Study of the Relationship between Dorsal and Ventral Tier Nigral Neurons and the Striosome/Matrix Striatal Compartments , 2001, The Journal of Neuroscience.
[146] T. Kaneko,et al. In Vivo Transduction of Central Neurons Using Recombinant Sindbis Virus , 2001, The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society.
[147] M. Rice,et al. H(2)O(2) is a novel, endogenous modulator of synaptic dopamine release. , 2001, Journal of neurophysiology.
[148] J. Adelman,et al. Structure of the gating domain of a Ca2+-activated K+ channel complexed with Ca2+/calmodulin , 2001, Nature.
[149] Jochen Roeper,et al. Differential Expression of the Small-Conductance, Calcium-Activated Potassium Channel SK3 Is Critical for Pacemaker Control in Dopaminergic Midbrain Neurons , 2001, The Journal of Neuroscience.
[150] S. Laughlin,et al. An Energy Budget for Signaling in the Grey Matter of the Brain , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[151] P. Lansbury,et al. Neurodegenerative disease: Amyloid pores from pathogenic mutations , 2002, Nature.
[152] L. Netchiporouk,et al. Lactate in the brain of the freely moving rat: voltammetric monitoring of the changes related to the sleep–wake states , 2002, The European journal of neuroscience.
[153] Peter Herscovitch,et al. Age, sex and laterality effects on cerebral glucose metabolism in healthy adults , 2002, Psychiatry Research: Neuroimaging.
[154] T. Sherer,et al. Environment, Mitochondria, and Parkinson's Disease , 2002, The Neuroscientist : a review journal bringing neurobiology, neurology and psychiatry.
[155] S. Jazwinski,et al. Growing old: metabolic control and yeast aging. , 2002, Annual review of microbiology.
[156] J. González-Mora,et al. In vivo electrochemical measurement of nitric oxide in corpus cavernosum penis , 2002, Journal of Neuroscience Methods.
[157] Denis Noble,et al. The IUPS human physiome project , 2002, Pflügers Archiv.
[158] J. Campisi,et al. Cancer and aging: a model for the cancer promoting effects of the aging stroma. , 2002, The international journal of biochemistry & cell biology.
[159] N. Lecture. A Half-Century of Neurotransmitter Research: Impact on Neurology and Psychiatry , 2002 .
[160] A. Gjedde. Coupling of Blood Flow to Neuronal Excitability , 2002 .
[161] H. Kitano. Systems Biology: A Brief Overview , 2002, Science.
[162] Robert Costalat,et al. A Model of the Coupling between Brain Electrical Activity, Metabolism, and Hemodynamics: Application to the Interpretation of Functional Neuroimaging , 2002, NeuroImage.
[163] S. Izenwasser,et al. Tolerance and sensitization to the locomotor-activating effects of cocaine are mediated via independent mechanisms , 2002, Pharmacology Biochemistry and Behavior.
[164] Takeshi Kaneko,et al. The Rostral Raphe Pallidus Nucleus Mediates Pyrogenic Transmission from the Preoptic Area , 2002, The Journal of Neuroscience.
[165] Katherine C. Chen,et al. Sniffers, buzzers, toggles and blinkers: dynamics of regulatory and signaling pathways in the cell. , 2003, Current opinion in cell biology.
[166] Resolving dynamic changes in brain metabolism using biosensors and on-line microdialysis , 2003 .
[167] J. Lowry,et al. Microelectrochemical sensors for in vivo brain analysis: an investigation of procedures for modifying Pt electrodes using Nafion. , 2003, The Analyst.
[168] Lorene M Nelson,et al. Incidence of Parkinson's disease: variation by age, gender, and race/ethnicity. , 2003, American journal of epidemiology.
[169] P. Jenner,et al. Oxidative stress in Parkinson's disease , 2003, Annals of neurology.
[170] Stanley N Cohen,et al. Senescence-specific gene expression fingerprints reveal cell-type-dependent physical clustering of up-regulated chromosomal loci , 2003, Proceedings of the National Academy of Sciences of the United States of America.
[171] C. Harris,et al. Rapid Akt activation by nicotine and a tobacco carcinogen modulates the phenotype of normal human airway epithelial cells. , 2003, The Journal of clinical investigation.
[172] L. Pellerin. Lactate as a pivotal element in neuron–glia metabolic cooperation , 2003, Neurochemistry International.
[173] B. Lancaster,et al. SK channels and the varieties of slow after‐hyperpolarizations in neurons , 2003, The European journal of neuroscience.
[174] N. Kulagina,et al. Monitoring hydrogen peroxide in the extracellular space of the brain with amperometric microsensors. , 2003, Analytical chemistry.
[175] H. Braak,et al. Staging of brain pathology related to sporadic Parkinson’s disease , 2003, Neurobiology of Aging.
[176] A. Matsumura,et al. Awakenings from persistent vegetative state: report of three cases with parkinsonism and brain stem lesions on MRI , 2003, Journal of neurology, neurosurgery, and psychiatry.
[177] Charles J. Wilson,et al. Apamin-Sensitive Small Conductance Calcium-Activated Potassium Channels, through their Selective Coupling to Voltage-Gated Calcium Channels, Are Critical Determinants of the Precision, Pace, and Pattern of Action Potential Generation in Rat Subthalamic Nucleus Neurons In Vitro , 2003, The Journal of Neuroscience.
[178] N. Avadhani,et al. Mitochondrial signaling: the retrograde response. , 2004, Molecular cell.
[179] K. A. Trujillo,et al. Continuous administration of opioids produces locomotor sensitization , 2004, Pharmacology Biochemistry and Behavior.
[180] Seung-Cheol Chang,et al. Comparisons of platinum, gold, palladium and glassy carbon as electrode materials in the design of biosensors for glutamate. , 2004, Biosensors & bioelectronics.
[181] B. Sokhansanj,et al. Oxidative DNA damage background estimated by a system model of base excision repair. , 2004, Free radical biology & medicine.
[182] Takeshi Kaneko,et al. Identification of Sympathetic Premotor Neurons in Medullary Raphe Regions Mediating Fever and Other Thermoregulatory Functions , 2004, The Journal of Neuroscience.
[183] Anthony Varghese,et al. Computing Transient Gating Charge Movement of Voltage-Dependent Ion Channels , 2002, Journal of Computational Neuroscience.
[184] J. Adelman,et al. Small conductance Ca2+‐activated K+ channels and calmodulin , 2004, The Journal of physiology.
[185] H. Braak,et al. Poor and protracted myelination as a contributory factor to neurodegenerative disorders , 2004, Neurobiology of Aging.
[186] K. Davies,et al. Decreased proteolysis caused by protein aggregates, inclusion bodies, plaques, lipofuscin, ceroid, and 'aggresomes' during oxidative stress, aging, and disease. , 2004, The international journal of biochemistry & cell biology.
[187] L. Glimcher,et al. Endoplasmic Reticulum Stress Links Obesity, Insulin Action, and Type 2 Diabetes , 2004, Science.
[188] Shile Huang,et al. Inhibition of Mammalian Target of Rapamycin Activates Apoptosis Signal-regulating Kinase 1 Signaling by Suppressing Protein Phosphatase 5 Activity* , 2004, Journal of Biological Chemistry.
[189] E. Masliah,et al. Enhanced substantia nigra mitochondrial pathology in human α-synuclein transgenic mice after treatment with MPTP 1 1 1-Methyl-4-phenyl-1,2,3,6-tetrahydropyridine. , 2004, Experimental Neurology.
[190] B. Bunney,et al. Repetitive firing properties of putative dopamine-containing neurons in vitro: regulation by an apamin-sensitive Ca2+-activated K+ conductance , 2004, Experimental Brain Research.
[191] T. Murphy,et al. Regulation of dendritic branching and filopodia formation in hippocampal neurons by specific acylated protein motifs. , 2004, Molecular biology of the cell.
[192] W. Frontera,et al. IKKβ/NF-κB Activation Causes Severe Muscle Wasting in Mice , 2004, Cell.
[193] M. Stocker. Ca2+-activated K+ channels: molecular determinants and function of the SK family , 2004, Nature Reviews Neuroscience.
[194] Angus C Nairn,et al. DARPP-32: an integrator of neurotransmission. , 2004, Annual review of pharmacology and toxicology.
[195] J. Adelman,et al. Regional distribution of SK3 mRNA‐containing neurons in the adult and adolescent rat ventral midbrain and their relationship to dopamine‐containing cells , 2004, Synapse.
[196] A. Schober,et al. Genes, proteins, and neurotoxins involved in Parkinson’s disease , 2004, Progress in Neurobiology.
[197] Carmen C Canavier,et al. A modeling study suggests complementary roles for GABAA and NMDA receptors and the SK channel in regulating the firing pattern in midbrain dopamine neurons. , 2004, Journal of neurophysiology.
[198] A. J. Valente,et al. Nuclear factor kappa B activation by NADPH oxidases , 2004, Mechanisms of Ageing and Development.
[199] Interplay between ER Ca2+ uptake and release fluxes in neurons and its impact on [Ca2+] dynamics. , 2004, Biological research.
[200] Hansjürgen Bratzke,et al. Stages in the development of Parkinson’s disease-related pathology , 2004, Cell and Tissue Research.
[201] L. Moran,et al. Whole genome expression profiling of the medial and lateral substantia nigra in Parkinson’s disease , 2006, Neurogenetics.
[202] G. Gerhardt,et al. L-lactate measures in brain tissue with ceramic-based multisite microelectrodes. , 2005, Biosensors & bioelectronics.
[203] B. Westerink,et al. Improving glutamate microsensors by optimizing the composition of the redox hydrogel. , 2005, Analytical chemistry.
[204] Pierre J Magistretti,et al. Brain lactate kinetics: Modeling evidence for neuronal lactate uptake upon activation. , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[205] D. Allan Butterfield,et al. Mitochondrial associated metabolic proteins are selectively oxidized in A30P α-synuclein transgenic mice—a model of familial Parkinson's disease , 2005, Neurobiology of Disease.
[206] M. Fillenz. The role of lactate in brain metabolism , 2005, Neurochemistry International.
[207] N. Barzilai,et al. Biological evidence for inheritance of exceptional longevity , 2005, Mechanisms of Ageing and Development.
[208] John P. Lowry,et al. Brain Tissue Oxygen: In Vivo Monitoring with Carbon Paste Electrodes , 2005, Sensors (Basel, Switzerland).
[209] Jean-François Liégeois,et al. SK channels control the firing pattern of midbrain dopaminergic neurons in vivo , 2005, The European journal of neuroscience.
[210] A. Hsu,et al. New Genes Tied to Endocrine, Metabolic, and Dietary Regulation of Lifespan from a Caenorhabditis elegans Genomic RNAi Screen , 2005, PLoS genetics.
[211] U. Misgeld,et al. Two pathways for the activation of small-conductance potassium channels in neurons of substantia nigra pars reticulata , 2005, Neuroscience.
[212] S. Castiglioni,et al. Iterleukin 1 alpha is a marker of endothelial cellular senescent , 2006, Immunity & Ageing.
[213] Akira Matsumura,et al. Levodopa treatment for patients in persistent vegetative or minimally conscious states , 2005, Neuropsychological rehabilitation.
[214] Darren J. Wilkinson,et al. Modelling the actions of chaperones and their role in ageing , 2005, Mechanisms of Ageing and Development.
[215] Richard S. Sutton,et al. Reinforcement Learning: An Introduction , 1998, IEEE Trans. Neural Networks.
[216] Jochen Roeper,et al. K-ATP channels promote the differential degeneration of dopaminergic midbrain neurons , 2005, Nature Neuroscience.
[217] B. Sabatini,et al. SK channels and NMDA receptors form a Ca2+-mediated feedback loop in dendritic spines , 2005, Nature Neuroscience.
[218] Nikolas Offenhauser,et al. Activity‐induced tissue oxygenation changes in rat cerebellar cortex: interplay of postsynaptic activation and blood flow , 2005, The Journal of physiology.
[219] H. Kitano,et al. A comprehensive pathway map of epidermal growth factor receptor signaling , 2005, Molecular systems biology.
[220] G. Westbrook,et al. SK channel regulation of dendritic excitability and dendrodendritic inhibition in the olfactory bulb. , 2005, Journal of neurophysiology.
[221] S. Przedborski. Pathogenesis of nigral cell death in Parkinson's disease. , 2005, Parkinsonism & related disorders.
[222] Carole J. Proctor,et al. An in silico model of the ubiquitin-proteasome system that incorporates normal homeostasis and age-related decline , 2007, BMC Systems Biology.
[223] J. Tschopp,et al. Signals from within: the DNA-damage-induced NF-κB response , 2006, Cell Death and Differentiation.
[224] G. Barja,et al. Testing the vicious cycle theory of mitochondrial ROS production: effects of H2O2 and cumene hydroperoxide treatment on heart mitochondria , 2006, Journal of bioenergetics and biomembranes.
[225] C. Finch,et al. A perspective on sporadic inclusion-body myositis , 2006, Neurology.
[226] Nicolas Le Novère,et al. DARPP-32 Is a Robust Integrator of Dopamine and Glutamate Signals , 2006, PLoS Comput. Biol..
[227] B. Westerink,et al. Evaluation of hydrogel-coated glutamate microsensors. , 2006, Analytical chemistry.
[228] Jeanette Kotaleski,et al. Transient Calcium and Dopamine Increase PKA Activity and DARPP-32 Phosphorylation , 2006, PLoS Comput. Biol..
[229] Albert Gjedde,et al. Neuronal–Glial Glucose Oxidation and Glutamatergic–GABAergic Function , 2006, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[230] Kevin G Becker,et al. Transcriptional Profiling of Aging in Human Muscle Reveals a Common Aging Signature , 2006, PLoS genetics.
[231] Mats Jirstrand,et al. Systems biology Systems Biology Toolbox for MATLAB : a computational platform for research in systems biology , 2006 .
[232] C. Canavier,et al. An increase in AMPA and a decrease in SK conductance increase burst firing by different mechanisms in a model of a dopamine neuron in vivo. , 2006, Journal of neurophysiology.
[233] E. Stadtman. Protein oxidation and aging. , 1992, Free radical research.
[234] F. Gorin,et al. Dynamic modeling of alpha-synuclein aggregation for the sporadic and genetic forms of Parkinson’s disease , 2006, Neuroscience.
[235] T. Humby,et al. Age‐related decline in striatal dopamine content and motor performance occurs in the absence of nigral cell loss in a genetic mouse model of Parkinson's disease , 2006, The European journal of neuroscience.
[236] M. Youdim,et al. Monoamine oxidase: isoforms and inhibitors in Parkinson's disease and depressive illness , 2006, British journal of pharmacology.
[237] H. Braak,et al. Gastric α-synuclein immunoreactive inclusions in Meissner's and Auerbach's plexuses in cases staged for Parkinson's disease-related brain pathology , 2006, Neuroscience Letters.
[238] J. Hudak,et al. Identification of the proteasome inhibitor MG262 as a potent ATP-dependent inhibitor of the Salmonella enterica serovar Typhimurium Lon protease. , 2006, Biochemistry.
[239] B. Westerink,et al. In vivo monitoring of extracellular glutamate in the brain with a microsensor , 2006, Brain Research.
[240] William J. Bosl,et al. Systems biology by the rules: hybrid intelligent systems for pathway modeling and discovery , 2007, BMC Systems Biology.
[241] R. A. Butow,et al. Mitochondrial retrograde signaling. , 2006, Annual review of genetics.
[242] M. Breteler,et al. Epidemiology of Parkinson's disease , 2006, The Lancet Neurology.
[243] Beate Ritz,et al. Gain-of-function haplotypes in the vesicular monoamine transporter promoter are protective for Parkinson disease in women. , 2006, Human molecular genetics.
[244] N. Wood,et al. Expanding insights of mitochondrial dysfunction in Parkinson's disease , 2006, Nature Reviews Neuroscience.
[245] Eugene M. Izhikevich,et al. Dynamical Systems in Neuroscience: The Geometry of Excitability and Bursting , 2006 .
[246] I. Rosenberg,et al. Nutrition and aging: changes in the regulation of energy metabolism with aging. , 2006, Physiological reviews.
[247] E. Hirsch,et al. Regional vulnerability of mesencephalic dopaminergic neurons prone to degenerate in Parkinson's disease: A post-mortem study in human control subjects , 2006, Neurobiology of Disease.
[248] Jan Vijg,et al. Increased cell-to-cell variation in gene expression in ageing mouse heart , 2006, Nature.
[249] O. Porras,et al. A quantitative overview of glucose dynamics in the gliovascular unit , 2007, Glia.
[250] H. Fernandez,et al. Monamine Oxidase Inhibitors: Current and Emerging Agents for Parkinson Disease , 2007, Clinical neuropharmacology.
[251] R. Takahashi,et al. Expanding insights on the involvement of endoplasmic reticulum stress in Parkinson's disease. , 2007, Antioxidants & redox signaling.
[252] B. Bean,et al. Roles of Subthreshold Calcium Current and Sodium Current in Spontaneous Firing of Mouse Midbrain Dopamine Neurons , 2007, The Journal of Neuroscience.
[253] Paolo Calabresi,et al. Dopamine-mediated regulation of corticostriatal synaptic plasticity , 2007, Trends in Neurosciences.
[254] Gary W. Miller,et al. Reduced Vesicular Storage of Dopamine Causes Progressive Nigrostriatal Neurodegeneration , 2007, The Journal of Neuroscience.
[255] K. Conley,et al. Mitochondrial function, fibre types and ageing: new insights from human muscle in vivo , 2007, Experimental physiology.
[256] P. Magistretti,et al. Activity‐dependent regulation of energy metabolism by astrocytes: An update , 2007, Glia.
[257] Howard E. Gendelman,et al. Selective inhibition of NF-κB activation prevents dopaminergic neuronal loss in a mouse model of Parkinson's disease , 2007, Proceedings of the National Academy of Sciences.
[258] KouichiC . Nakamura,et al. Gamma-aminobutyric acid-containing sympathetic preganglionic neurons in rat thoracic spinal cord send their axons to the superior cervical ganglion. , 2007, The Journal of comparative neurology.
[259] Robert E Burke,et al. Sir Charles Sherrington's the integrative action of the nervous system: a centenary appreciation. , 2006, Brain : a journal of neurology.
[260] J. Padiadpu,et al. Integrating glutathione metabolism and mitochondrial dysfunction with implications for Parkinson’s disease: A dynamic model , 2007, Neuroscience.
[261] Angus M. Brown,et al. Astrocyte glycogen and brain energy metabolism , 2007, Glia.
[262] A. Kriete,et al. CIDE-A is expressed in liver of old mice and in type 2 diabetic mouse liver exhibiting steatosis , 2007, Comparative hepatology.
[263] Eran Segal,et al. Motif module map reveals enforcement of aging by continual NF-κB activity , 2007 .
[264] D. Maraganore,et al. A Genomic Pathway Approach to a Complex Disease: Axon Guidance and Parkinson Disease , 2007, PLoS genetics.
[265] J. Lowry,et al. Development and characterization in vitro of a catalase-based biosensor for hydrogen peroxide monitoring. , 2007, Biosensors & bioelectronics.
[266] Andreas Schober,et al. GDNF applied to the MPTP-lesioned nigrostriatal system requires TGF-β for its neuroprotective action , 2007, Neurobiology of Disease.
[267] V. Krishnan Ramanujan,et al. Aging Process Modulates Nonlinear Dynamics in Liver Cell Metabolism* , 2007, Journal of Biological Chemistry.
[268] Leslie Greengard,et al. A mathematical tool for exploring the dynamics of biological networks , 2007, Proceedings of the National Academy of Sciences.
[269] Direct pyrogenic input from prostaglandin EP3 receptor-expressing preoptic neurons to the dorsomedial hypothalamus , 2007 .
[270] A. Björklund,et al. Dopamine neuron systems in the brain: an update , 2007, Trends in Neurosciences.
[271] P. Kakkar,et al. Mitochondria: a hub of redox activities and cellular distress control , 2007, Molecular and Cellular Biochemistry.
[272] A. Owen,et al. AGEMAP: A Gene Expression Database for Aging in Mice , 2007, PLoS genetics.
[273] Robert Roskoski. Michaelis-Menten Kinetics , 2007 .
[274] D. James Surmeier,et al. ‘Rejuvenation’ protects neurons in mouse models of Parkinson’s disease , 2007, Nature.
[275] D. Surmeier,et al. Calcium, ageing, and neuronal vulnerability in Parkinson's disease , 2007, The Lancet Neurology.
[276] A. Navarro,et al. The mitochondrial energy transduction system and the aging process. , 2007, American journal of physiology. Cell physiology.
[277] Roberto G Lucchini,et al. High prevalence of Parkinsonian disorders associated to manganese exposure in the vicinities of ferroalloy industries. , 2007, American journal of industrial medicine.
[278] Judith Campisi,et al. Senescence-Associated Secretory Phenotypes Reveal Cell-Nonautonomous Functions of Oncogenic RAS and the p53 Tumor Suppressor , 2008, PLoS biology.
[279] Thomas P. Minka,et al. Gates , 2008, NIPS.
[280] Peter Wellstead,et al. Systems Biology and the Spirit of Tustin , 2008 .
[281] M. Cookson. α-Synuclein and neuronal cell death , 2009, Molecular Neurodegeneration.
[282] David T. Yue,et al. Mechanism of Local and Global Ca2+ Sensing by Calmodulin in Complex with a Ca2+ Channel , 2008, Cell.
[283] Jean-François Liégeois,et al. SK channel blockade promotes burst firing in dorsal raphe serotonergic neurons , 2008, The European journal of neuroscience.
[284] Michael J Thun,et al. Recreational physical activity and risk of Parkinson's disease , 2008, Movement disorders : official journal of the Movement Disorder Society.
[285] G. Deuschl,et al. Neuronal activity of the human subthalamic nucleus in the parkinsonian and nonparkinsonian state. , 2008, Journal of neurophysiology.
[286] T. Videen,et al. Cerebral Mitochondrial Metabolism in Early Parkinson's Disease , 2008, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[287] Mei Liu,et al. Trichloroethylene: Parkinsonism and complex 1 mitochondrial neurotoxicity , 2008, Annals of neurology.
[288] N. Sondheimer,et al. A Distinctive Physiological Role for IκBβ in the Propagation of Mitochondrial Respiratory Stress Signaling* , 2008, Journal of Biological Chemistry.
[289] Eberhard O. Voit,et al. Computational Systems Analysis of Dopamine Metabolism , 2008, PloS one.
[290] A. Schapira. Mitochondria in the aetiology and pathogenesis of Parkinson's disease. , 1999, The Lancet. Neurology.
[291] Claudia C. Preston,et al. Aging-induced alterations in gene transcripts and functional activity of mitochondrial oxidative phosphorylation complexes in the heart , 2008, Mechanisms of Ageing and Development.
[292] Robert D. O'Neill,et al. Designing sensitive and selective polymer/enzyme composite biosensors for brain monitoring in vivo , 2008 .
[293] Daniel A Beard,et al. Phosphate metabolite concentrations and ATP hydrolysis potential in normal and ischaemic hearts , 2008, The Journal of physiology.
[294] S. Nuzhdin,et al. Natural genetic variation in transcriptome reflects network structure inferred with major effect mutations: insulin/TOR and associated phenotypes in Drosophila melanogaster , 2009, BMC Genomics.
[295] J. Obeso,et al. Functional organization of the basal ganglia: Therapeutic implications for Parkinson's disease , 2008, Movement disorders : official journal of the Movement Disorder Society.
[296] J. Tepper,et al. GABAergic Afferents Activate Both GABAA and GABAB Receptors in Mouse Substantia Nigra Dopaminergic Neurons In Vivo , 2008, The Journal of Neuroscience.
[297] L. Greene,et al. RTP801 Is Induced in Parkinson's Disease and Mediates Neuron Death by Inhibiting Akt Phosphorylation/Activation , 2008, The Journal of Neuroscience.
[298] E O Voit,et al. Steps of Modeling Complex Biological Systems , 2008, Pharmacopsychiatry.
[299] N. Avadhani,et al. Mitochondrial Import and Accumulation of α-Synuclein Impair Complex I in Human Dopaminergic Neuronal Cultures and Parkinson Disease Brain* , 2008, Journal of Biological Chemistry.
[300] Judy H. Cho,et al. Finding the missing heritability of complex diseases , 2009, Nature.
[301] John P. Horn,et al. Cav1.3 Channel Voltage Dependence, Not Ca2+ Selectivity, Drives Pacemaker Activity and Amplifies Bursts in Nigral Dopamine Neurons , 2009, The Journal of Neuroscience.
[302] D. Sulzer,et al. Interplay between Cytosolic Dopamine, Calcium, and α-Synuclein Causes Selective Death of Substantia Nigra Neurons , 2009, Neuron.
[303] J. Callaway,et al. Endogenous calcium buffering capacity of substantia nigral dopamine neurons. , 2009, Journal of neurophysiology.
[304] Marco Pahor,et al. Rapamycin fed late in life extends lifespan in genetically heterogeneous mice , 2009, Nature.
[305] V. Subramaniam,et al. Lipid bilayer disruption by oligomeric alpha-synuclein depends on bilayer charge and accessibility of the hydrophobic core. , 2009, Biochimica et biophysica acta.
[306] M. Bevan,et al. Cellular Mechanisms Underlying Burst Firing in Substantia Nigra Dopamine Neurons , 2009, The Journal of Neuroscience.
[307] C. Wass,et al. Increased cortical nitric oxide release after phencyclidine administration , 2009, Synapse.
[308] F. Fujiyama,et al. Single Nigrostriatal Dopaminergic Neurons Form Widely Spread and Highly Dense Axonal Arborizations in the Neostriatum , 2009, The Journal of Neuroscience.
[309] C. Oliveira,et al. Endoplasmic reticulum and mitochondria interplay mediates apoptotic cell death: Relevance to Parkinson's disease , 2009, Neurochemistry International.
[310] D. Surmeier,et al. Calcium homeostasis, selective vulnerability and Parkinson's disease , 2009, Trends in Neurosciences.
[311] John P. Lowry,et al. An integrative dynamic model of brain energy metabolism using in vivo neurochemical measurements , 2009, Journal of Computational Neuroscience.
[312] L. Hood,et al. Systems medicine: the future of medical genomics and healthcare , 2009, Genome Medicine.
[313] T. González-Hernández,et al. Phenotype, compartmental organization and differential vulnerability of nigral dopaminergic neurons. , 2009, Journal of neural transmission. Supplementum.
[314] D. Strøbæk,et al. Tuning the excitability of midbrain dopamine neurons by modulating the Ca2+ sensitivity of SK channels , 2009, The European journal of neuroscience.
[315] H. Nijhout,et al. Theoretical Biology and Medical Modelling Open Access Homeostatic Mechanisms in Dopamine Synthesis and Release: a Mathematical Model , 2022 .
[316] Andrew J. Lees,et al. Dopamine Dysregulation Syndrome , 2008, CNS drugs.
[317] H. Pape,et al. Burst discharges in neurons of the thalamic reticular nucleus are shaped by calcium-induced calcium release. , 2009, Cell calcium.
[318] Eberhard O Voit,et al. Computational analysis of determinants of dopamine (DA) dysfunction in DA nerve terminals , 2009, Synapse.
[319] Mathieu Cloutier,et al. The control systems structures of energy metabolism , 2010, Journal of The Royal Society Interface.
[320] M. Beal,et al. Combination therapy with Coenzyme Q10 and creatine produces additive neuroprotective effects in models of Parkinson’s and Huntington’s Diseases , 2009, Journal of neurochemistry.
[321] B. Tilley,et al. Determinants of the timing of symptomatic treatment in early Parkinson disease: The National Institutes of Health Exploratory Trials in Parkinson Disease (NET-PD) Experience. , 2009, Archives of neurology.
[322] D. James Surmeier,et al. Robust Pacemaking in Substantia Nigra Dopaminergic Neurons , 2009, The Journal of Neuroscience.
[323] Eberhard O. Voit,et al. The internal state of medium spiny neurons varies in response to different input signals , 2010, BMC Systems Biology.
[324] D. Surmeier,et al. A molecular basis for the increased vulnerability of substantia nigra dopamine neurons in aging and Parkinson's disease , 2010, Movement disorders : official journal of the Movement Disorder Society.
[325] Paul T. Schumacker,et al. Oxidant stress evoked by pacemaking in dopaminergic neurons is attenuated by DJ-1 , 2010, Nature.
[326] P. Christophersen,et al. Pharmacological modulation of the gating properties of small conductance Ca2+-activated K+ channels alters the firing pattern of dopamine neurons in vivo. , 2010, Journal of neurophysiology.
[327] E O Voit,et al. Computational Modeling of Synaptic Neurotransmission as a Tool for Assessing Dopamine Hypotheses of Schizophrenia , 2010, Pharmacopsychiatry.
[328] Andres Kriete,et al. Rule-Based Cell Systems Model of Aging using Feedback Loop Motifs Mediated by Stress Responses , 2010, PLoS Comput. Biol..
[329] Charles J. Wilson,et al. A dynamic role for GABA receptors on the firing pattern of midbrain dopaminergic neurons. , 2010, Journal of neurophysiology.
[330] D James Surmeier,et al. What causes the death of dopaminergic neurons in Parkinson's disease? , 2010, Progress in brain research.
[331] K. H. Lee,et al. Pregnenolone sulfate enhances spontaneous glutamate release by inducing presynaptic Ca2+-induced Ca2+ release , 2010, Neuroscience.
[332] M. Ungless,et al. Hyperexcitable substantia nigra dopamine neurons in PINK1- and HtrA2/Omi-deficient mice. , 2010, Journal of neurophysiology.
[333] John P. Lowry,et al. Real-time electrochemical monitoring of brain tissue oxygen: A surrogate for functional magnetic resonance imaging in rodents , 2010, NeuroImage.
[334] D. Surmeier,et al. Calcium, cellular aging, and selective neuronal vulnerability in Parkinson's disease. , 2010, Cell calcium.
[335] T. Myöhänen,et al. Distribution of catechol‐O‐methyltransferase (COMT) proteins and enzymatic activities in wild‐type and soluble COMT deficient mice , 2010, Journal of neurochemistry.
[336] Ted M. Dawson,et al. Genetic Animal Models of Parkinson's Disease , 2010, Neuron.
[337] Somratna Lertmaharith. Degree of freedom , 2010 .
[338] M. Farrer,et al. Missing pieces in the Parkinson's disease puzzle , 2010, Nature Medicine.
[339] Wesley E Bolch. The Monte Carlo Method in Nuclear Medicine: Current Uses and Future Potential , 2010, Journal of Nuclear Medicine.
[340] T. González-Hernández,et al. Vulnerability of Mesostriatal Dopaminergic Neurons in Parkinson's Disease , 2010, Front. Neuroanat..
[341] R. Betensky,et al. Association of PGC-1alpha polymorphisms with age of onset and risk of Parkinson's disease , 2011, BMC Medical Genetics.
[342] Mark H. Ellisman,et al. Sestrin as a Feedback Inhibitor of TOR That Prevents Age-Related Pathologies , 2010, Science.
[343] P. Serra,et al. Design and Construction of a Distributed Sensor NET for Biotelemetric Monitoring of Brain Energetic Metabolism Using Microsensors and Biosensors , 2010 .
[344] J. Duda. Olfactory system pathology as a model of Lewy neurodegenerative disease , 2010, Journal of the Neurological Sciences.
[345] Fiachra B. Bolger,et al. Characterisation of carbon paste electrodes for real-time amperometric monitoring of brain tissue oxygen , 2011, Journal of Neuroscience Methods.
[346] Roded Sharan,et al. Genome-Scale Metabolic Modeling Elucidates the Role of Proliferative Adaptation in Causing the Warburg Effect , 2011, PLoS Comput. Biol..
[347] E O Voit,et al. Effects of Dopamine and Glutamate on Synaptic Plasticity: A Computational Modeling Approach for Drug Abuse as Comorbidity in Mood Disorders , 2011, Pharmacopsychiatry.
[348] Zhaoyang Feng,et al. Dysregulated LRRK2 Signaling in Response to Endoplasmic Reticulum Stress Leads to Dopaminergic Neuron Degeneration in C. elegans , 2011, PloS one.
[349] A. Cooper,et al. Predictive Reward Signal of Dopamine Neurons , 2011 .
[350] A. Schober,et al. Pten ablation in adult dopaminergic neurons is neuroprotective in Parkinson's disease models , 2011, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[351] Cole M. Haynes,et al. Mitochondrial protein quality control during biogenesis and aging. , 2011, Trends in biochemical sciences.
[352] Mathieu Cloutier,et al. An energy systems approach to Parkinson's disease , 2011, Wiley interdisciplinary reviews. Systems biology and medicine.
[353] D. Bourdette,et al. Mitochondrial calcium and its regulation in neurodegeneration induced by oxidative stress , 2011, The European journal of neuroscience.
[354] D. Surmeier,et al. The L-type channel antagonist isradipine is neuroprotective in a mouse model of Parkinson's disease , 2011, Neurobiology of Disease.
[355] J. Brotchie,et al. The serotonergic system in Parkinson's disease , 2011, Progress in Neurobiology.
[356] Rodolphe Sepulchre,et al. How Modeling Can Reconcile Apparently Discrepant Experimental Results: The Case of Pacemaking in Dopaminergic Neurons , 2011, PLoS Comput. Biol..
[357] M. Brini,et al. Mitochondria, calcium, and endoplasmic reticulum stress in Parkinson's disease. , 2011, BioFactors.
[358] Fiachra B. Bolger,et al. An in vitro characterisation comparing carbon paste and Pt microelectrodes for real-time detection of brain tissue oxygen. , 2011, The Analyst.
[359] E. Bézard,et al. A tale on animal models of Parkinson's disease , 2011, Movement disorders : official journal of the Movement Disorder Society.
[360] F. Sterky,et al. Impaired mitochondrial transport and Parkin-independent degeneration of respiratory chain-deficient dopamine neurons in vivo , 2011, Proceedings of the National Academy of Sciences.
[361] Terina N. Martinez,et al. Toxin models of mitochondrial dysfunction in Parkinson's disease. , 2012, Antioxidants & redox signaling.
[362] P. Wellstead,et al. Feedback motif for the pathogenesis of Parkinson's disease. , 2012, IET systems biology.
[363] P. Wellstead,et al. Dynamic modelling of protein and oxidative metabolisms simulates the pathogenesis of Parkinson's disease. , 2012, IET systems biology.
[364] E. Hirsch,et al. Pathogenesis of Parkinson's disease , 2013, Movement disorders : official journal of the Movement Disorder Society.
[365] S. W. Mitchell,et al. Wear and tear , 1871 .