Development of spirulina for the manufacture and oral delivery of protein therapeutics

[1]  H. Kiyono,et al.  Development of Antibody-Fragment–Producing Rice for Neutralization of Human Norovirus , 2021, Frontiers in Plant Science.

[2]  E. Egelman,et al.  Atomic structure of the Campylobacter jejuni flagellar filament reveals how ε Proteobacteria escaped Toll-like receptor 5 surveillance , 2020, Proceedings of the National Academy of Sciences.

[3]  N. Callewaert,et al.  Structural Basis for Potent Neutralization of Betacoronaviruses by Single-Domain Camelid Antibodies , 2020, Cell.

[4]  P. Bradley,et al.  Engineering and functionalization of large circular tandem repeat protein nanoparticles , 2020, Nature Structural & Molecular Biology.

[5]  P. Ralph,et al.  Emerging Technologies in Algal Biotechnology: Toward the Establishment of a Sustainable, Algae-Based Bioeconomy , 2020, Frontiers in Plant Science.

[6]  Scott A. Rifkin,et al.  The circadian clock and darkness control natural competence in cyanobacteria , 2019, Nature Communications.

[7]  S. Schillberg,et al.  Critical Analysis of the Commercial Potential of Plants for the Production of Recombinant Proteins , 2019, Front. Plant Sci..

[8]  Gregory L. Medlock,et al.  A novel mouse model of Campylobacter jejuni enteropathy and diarrhea , 2018, bioRxiv.

[9]  G. Hansman,et al.  Nanobodies targeting norovirus capsid reveal functional epitopes and potential mechanisms of neutralization , 2017, PLoS pathogens.

[10]  M. Levine,et al.  Global burden of diarrheal diseases among children in developing countries: Incidence, etiology, and insights from new molecular diagnostic techniques. , 2017, Vaccine.

[11]  M. Seeger,et al.  Synthetic single domain antibodies for the conformational trapping of membrane proteins , 2017, bioRxiv.

[12]  D. Tribble,et al.  Prophylactic Efficacy of Hyperimmune Bovine Colostral Antiadhesin Antibodies Against Enterotoxigenic Escherichia coli Diarrhea: A Randomized, Double-Blind, Placebo-Controlled, Phase 1 Trial , 2017, The Journal of infectious diseases.

[13]  S. Cheevadhanarak,et al.  Overcoming Intrinsic Restriction Enzyme Barriers Enhances Transformation Efficiency in Arthrospira platensis C1 , 2017, Plant & cell physiology.

[14]  Yue Jiang,et al.  Chlorella species as hosts for genetic engineering and expression of heterologous proteins: Progress, challenge and perspective , 2016, Biotechnology journal.

[15]  Fatima Aziz,et al.  Use of quantitative molecular diagnostic methods to identify causes of diarrhoea in children: a reanalysis of the GEMS case-control study , 2016, The Lancet.

[16]  Paola Lettieri,et al.  Life‐cycle and cost of goods assessment of fed‐batch and perfusion‐based manufacturing processes for mAbs , 2016, Biotechnology progress.

[17]  Susan S. Taylor,et al.  Structure of smAKAP and its regulation by PKA‐mediated phosphorylation , 2016, The FEBS journal.

[18]  Mark A. Miller,et al.  Pathogen-specific burdens of community diarrhoea in developing countries: a multisite birth cohort study (MAL-ED). , 2015, The Lancet. Global health.

[19]  S. Tzipori,et al.  Hyperimmune bovine colostrum as a novel therapy to combat Clostridium difficile infection. , 2014, The Journal of infectious diseases.

[20]  D. Schmidt,et al.  A novel multivalent, single-domain antibody targeting TcdA and TcdB prevents fulminant Clostridium difficile infection in mice. , 2014, The Journal of infectious diseases.

[21]  J. Mell,et al.  Natural Competence and the Evolution of DNA Uptake Specificity , 2014, Journal of bacteriology.

[22]  C. Szymanski,et al.  Pentavalent Single-Domain Antibodies Reduce Campylobacter jejuni Motility and Colonization in Chickens , 2013, PloS one.

[23]  L. Hammarström,et al.  Anti-rotavirus protein reduces stool output in infants with diarrhea: a randomized placebo-controlled trial. , 2013, Gastroenterology.

[24]  Serge Muyldermans,et al.  Nanobodies: natural single-domain antibodies. , 2013, Annual review of biochemistry.

[25]  Matteo Dal Peraro,et al.  Arranged sevenfold: structural insights into the C-terminal oligomerization domain of human C4b-binding protein. , 2013, Journal of molecular biology.

[26]  S. Tzipori,et al.  Hyperimmune bovine colostrum for treatment of GI infections , 2013, Human vaccines & immunotherapeutics.

[27]  Asawin Meechai,et al.  Systems biology and metabolic engineering of Arthrospira cell factories , 2012, Computational and structural biotechnology journal.

[28]  A. Klindworth,et al.  Evaluation of general 16S ribosomal RNA gene PCR primers for classical and next-generation sequencing-based diversity studies , 2012, Nucleic acids research.

[29]  S. A. Wilson,et al.  Recent advances towards development and commercialization of plant cell culture processes for the synthesis of biomolecules. , 2012, Plant biotechnology journal.

[30]  J. Tanha,et al.  Engineered Single-Domain Antibodies with High Protease Resistance and Thermal Stability , 2011, PloS one.

[31]  R. Robins-Browne,et al.  Randomized control trials using a tablet formulation of hyperimmune bovine colostrum to prevent diarrhea caused by enterotoxigenic Escherichia coli in volunteers , 2011, Scandinavian journal of gastroenterology.

[32]  S. Mayfield,et al.  Production of therapeutic proteins in algae, analysis of expression of seven human proteins in the chloroplast of Chlamydomonas reinhardtii. , 2010, Plant biotechnology journal.

[33]  L. Saif,et al.  Llama-Derived Single-Chain Antibody Fragments Directed to Rotavirus VP6 Protein Possess Broad Neutralizing Activity In Vitro and Confer Protection against Diarrhea in Mice , 2008, Journal of Virology.

[34]  A. Basit,et al.  Measurements of rat and mouse gastrointestinal pH, fluid and lymphoid tissue, and implications for in‐vivo experiments , 2008, The Journal of pharmacy and pharmacology.

[35]  D. Murphy.  Improving containment strategies in biopharming. , 2007, Plant biotechnology journal.

[36]  H. Kiyono,et al.  Rice-based mucosal vaccine as a global strategy for cold-chain- and needle-free vaccination , 2007, Proceedings of the National Academy of Sciences.

[37]  J. Fox.  Turning plants into protein factories , 2006, Nature Biotechnology.

[38]  Stefan Bertilsson,et al.  Evaluation of 23S rRNA PCR Primers for Use in Phylogenetic Studies of Bacterial Diversity , 2006, Applied and Environmental Microbiology.

[39]  Rainer Fischer,et al.  Molecular farming in plants: host systems and expression technology. , 2003, Trends in biotechnology.

[40]  J. Howard,et al.  Production of recombinant proteins in transgenic plants: Practical considerations , 1997, Biotechnology and bioengineering.

[41]  A. Hiatt,et al.  Production of antibodies in transgenic plants , 1989, Nature.

[42]  C. H. Lin,et al.  Cloning and expression of the human erythropoietin gene. , 1985, Proceedings of the National Academy of Sciences of the United States of America.

[43]  K. Amako,et al.  Motility as an intestinal colonization factor for Campylobacter jejuni. , 1985, Journal of general microbiology.

[44]  Gustav Ammerer,et al.  Expression of a human gene for interferon in yeast , 1981, Nature.

[45]  N. Adham,et al.  Profiles of pure pancreatic secretions obtained by direct pancreatic duct cannulation in normal healthy human subjects. , 1978, Gastroenterology.

[46]  G. Fink,et al.  Transformation of yeast. , 1978, Proceedings of the National Academy of Sciences of the United States of America.

[47]  A. Riggs,et al.  Expression in Escherichia coli of a chemically synthesized gene for the hormone somatostatin. , 1977, Science.

[48]  Richard Axel,et al.  Transfer of purified herpes virus thymidine kinase gene to cultured mouse cells , 1977, Cell.

[49]  A. C. Chang,et al.  Construction of biologically functional bacterial plasmids in vitro. , 1973, Proceedings of the National Academy of Sciences of the United States of America.