The transcription elongation factor TCEA3 induces apoptosis in rhabdomyosarcoma

[1]  Yunqin Yan,et al.  TCEA3 promotes differentiation of C2C12 cells via an Annexin A1‐mediated transforming growth factor‐β signaling pathway , 2019, Journal of cellular physiology.

[2]  P. Mullan,et al.  TBX2 interacts with heterochromatin protein 1 to recruit a novel repression complex to EGR1-targeted promoters to drive the proliferation of breast cancer cells , 2019, Oncogene.

[3]  J. Davie,et al.  The transcription elongation factor TCEA3 promotes the activity of the myogenic regulatory factors , 2019, PloS one.

[4]  J. Davie,et al.  TBX3 represses TBX2 under the control of the PRC2 complex in skeletal muscle and rhabdomyosarcoma , 2019, Oncogenesis.

[5]  Ashley R. Woodfin,et al.  Targeting Processive Transcription Elongation via SEC Disruption for MYC-Induced Cancer Therapy , 2018, Cell.

[6]  A. Almasan,et al.  Autophagy as a mechanism of Apo2L/TRAIL resistance , 2018, Cancer biology & therapy.

[7]  A. Shilatifard,et al.  Resetting the epigenetic balance of Polycomb and COMPASS function at enhancers for cancer therapy , 2018, Nature Medicine.

[8]  Mary Goldman,et al.  The UCSC Xena platform for public and private cancer genomics data visualization and interpretation , 2018, bioRxiv.

[9]  R. Young,et al.  Transcriptional Addiction in Cancer , 2017, Cell.

[10]  J. Khan,et al.  Myogenic regulatory transcription factors regulate growth in rhabdomyosarcoma , 2016, eLife.

[11]  A. Shilatifard,et al.  Epigenetic balance of gene expression by Polycomb and COMPASS families , 2016, Science.

[12]  J. Davie,et al.  TBX2 represses PTEN in rhabdomyosarcoma and skeletal muscle , 2015, Oncogene.

[13]  Jia Li,et al.  TCEA3 Attenuates Gastric Cancer Growth by Apoptosis Induction , 2015, Medical science monitor : international medical journal of experimental and clinical research.

[14]  Stephanie D. Byrum,et al.  TBX2 blocks myogenesis and promotes proliferation in rhabdomyosarcoma cells , 2014, International journal of cancer.

[15]  R. Boldrini,et al.  The Polycomb group (PcG) protein EZH2 supports the survival of PAX3-FOXO1 alveolar rhabdomyosarcoma by repressing FBXO32 (Atrogin1/MAFbx) , 2014, Oncogene.

[16]  R. Boldrini,et al.  Pharmacological inhibition of EZH2 as a promising differentiation therapy in embryonal RMS , 2014, BMC Cancer.

[17]  P. Holland Targeting Apo2L/TRAIL receptors by soluble Apo2L/TRAIL. , 2013, Cancer letters.

[18]  L. Kunkel,et al.  The cell biology of disease: cellular and molecular mechanisms underlying muscular dystrophy. , 2013, The Journal of cell biology.

[19]  Dae-Kwan Kim,et al.  TCEA3 binds to TGF-beta receptor I and induces Smad-independent, JNK-dependent apoptosis in ovarian cancer cells. , 2013, Cellular signalling.

[20]  Jonghwan Kim,et al.  Transcription Elongation Factor Tcea3 Regulates the Pluripotent Differentiation Potential of Mouse Embryonic Stem Cells Via the Lefty1‐Nodal‐Smad2 Pathway , 2013, Stem cells.

[21]  A. Giordano,et al.  Enhancer of zeste homolog 2 (EZH2) in pediatric soft tissue sarcomas: first implications , 2011, BMC medicine.

[22]  J. Davie,et al.  Sequential association of myogenic regulatory factors and E proteins at muscle-specific genes , 2011, Skeletal Muscle.

[23]  Sylvia E. Le Dévédec,et al.  Annexin A1 regulates TGF-β signaling and promotes metastasis formation of basal-like breast cancer cells , 2010, Proceedings of the National Academy of Sciences.

[24]  James R. Anderson,et al.  Vincristine, actinomycin, and cyclophosphamide compared with vincristine, actinomycin, and cyclophosphamide alternating with vincristine, topotecan, and cyclophosphamide for intermediate-risk rhabdomyosarcoma: children's oncology group study D9803. , 2009, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[25]  Stephen W. Fesik,et al.  Promoting apoptosis as a strategy for cancer drug discovery , 2005, Nature Reviews Cancer.

[26]  John Calvin Reed Apoptosis mechanisms: implications for cancer drug discovery. , 2004, Oncology.

[27]  R. Locksley,et al.  The TNF and TNF Receptor Superfamilies Integrating Mammalian Biology , 2001, Cell.

[28]  Nicholson,et al.  Cross-talk in cell death signaling , 2000, The Journal of experimental medicine.

[29]  D. Reines,et al.  Transcription elongation factor SII , 2000, BioEssays : news and reviews in molecular, cellular and developmental biology.

[30]  D. Hanahan,et al.  The Hallmarks of Cancer , 2000, Cell.

[31]  E. Slee,et al.  Serial killers: ordering caspase activation events in apoptosis , 1999, Cell Death and Differentiation.

[32]  L. Helman,et al.  Rhabdomyosarcoma: an overview. , 1999, The oncologist.

[33]  P. Labhart,et al.  Identification of novel genes encoding transcription elongation factor TFIIS (TCEA) in vertebrates: conservation of three distinct TFIIS isoforms in frog, mouse, and human. , 1998, Genomics.

[34]  V. Dixit,et al.  Death receptors: signaling and modulation. , 1998, Science.

[35]  J C Reed,et al.  Mitochondria and apoptosis. , 1998, Science.

[36]  D. Ferrari,et al.  Apoptosis signaling by death receptors. , 1998, European journal of biochemistry.

[37]  U. Thatte,et al.  Apoptosis: clinical relevance and pharmacological manipulation. , 1997, Drugs.

[38]  Xiaodong Wang,et al.  Apaf-1, a Human Protein Homologous to C. elegans CED-4, Participates in Cytochrome c–Dependent Activation of Caspase-3 , 1997, Cell.

[39]  P. Sorensen,et al.  Common and variant gene fusions predict distinct clinical phenotypes in rhabdomyosarcoma. , 1997, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[40]  Seamus J. Martin,et al.  Protease activation during apoptosis: Death by a thousand cuts? , 1995, Cell.

[41]  J. Downing,et al.  Fusion of PAX3 to a member of the forkhead family of transcription factors in human alveolar rhabdomyosarcoma. , 1993, Cancer research.

[42]  S. Tapscott,et al.  Deficiency in rhabdomyosarcomas of a factor required for MyoD activity and myogenesis. , 1993, Science.

[43]  W. Cavenee,et al.  Chromosomal localization of the human rhabdomyosarcoma locus by mitotic recombination mapping , 1987, Nature.

[44]  S H Kaufmann,et al.  Mammalian caspases: structure, activation, substrates, and functions during apoptosis. , 1999, Annual review of biochemistry.