C9orf72 promoter hypermethylation is neuroprotective
暂无分享,去创建一个
M. Grossman | C. McMillan | D. Irwin | Eddie B. Lee | Jenny Russ | L. McCluskey | L. Elman | E. Wood | Vivanna M Van Deerlin | V. V. Van Deerlin
[1] L. Petrucelli,et al. Characterization of DNA hypermethylation in the cerebellum of c9FTD/ALS patients , 2014, Brain Research.
[2] L. Ungar,et al. The power of neuroimaging biomarkers for screening frontotemporal dementia , 2014, Human brain mapping.
[3] D. Mann,et al. Brain distribution of dipeptide repeat proteins in frontotemporal lobar degeneration and motor neurone disease associated with expansions in C9ORF72 , 2014, Acta neuropathologica communications.
[4] P. S. St George-Hyslop,et al. Hypermethylation of the CpG-island near the C9orf72 G₄C₂-repeat expansion in FTLD patients. , 2014, Human molecular genetics.
[5] Brian B. Avants,et al. Genetic and neuroanatomic associations in sporadic frontotemporal lobar degeneration , 2014, Neurobiology of Aging.
[6] D. Irwin,et al. C9orf72 hypermethylation protects against repeat expansion-associated pathology in ALS/FTD , 2014, Acta Neuropathologica.
[7] I. Mackenzie,et al. The neuropathology associated with repeat expansions in the C9ORF72 gene , 2014, Acta Neuropathologica.
[8] Roberto Gasparotti,et al. Effect of TMEM106B polymorphism on functional network connectivity in asymptomatic GRN mutation carriers. , 2014, JAMA neurology.
[9] Brian B. Avants,et al. Sparse canonical correlation analysis relates network-level atrophy to multivariate cognitive measures in a neurodegenerative population , 2014, NeuroImage.
[10] Susan Byrne,et al. Basal ganglia involvement in amyotrophic lateral sclerosis , 2013, Neurology.
[11] M. Grossman,et al. Development and validation of pedigree classification criteria for frontotemporal lobar degeneration. , 2013, JAMA neurology.
[12] L. Petrucelli,et al. Reduced C9orf72 gene expression in c9FTD/ALS is caused by histone trimethylation, an epigenetic event detectable in blood , 2013, Acta Neuropathologica.
[13] S. Lorenzl,et al. Dipeptide repeat protein pathology in C9ORF72 mutation cases: clinico-pathological correlations , 2013, Acta Neuropathologica.
[14] C. Caltagirone,et al. Cognitive Reserve in Granulin-Related Frontotemporal Dementia: from Preclinical to Clinical Stages , 2013, PloS one.
[15] A. Bokde,et al. Multiparametric MRI study of ALS stratified for the C9orf72 genotype , 2013, Neurology.
[16] Murray Grossman,et al. Stages of pTDP‐43 pathology in amyotrophic lateral sclerosis , 2013, Annals of neurology.
[17] E. Rogaeva,et al. Hypermethylation of the CpG island near the G4C2 repeat in ALS with a C9orf72 expansion. , 2013, American journal of human genetics.
[18] Robert V Farese,et al. The advantages of frontotemporal degeneration drug development (part 2 of frontotemporal degeneration: The next therapeutic frontier) , 2013, Alzheimer's & Dementia.
[19] Jonathan M. Bekisz,et al. Cognitive decline and reduced survival in C9orf72 expansion frontotemporal degeneration and amyotrophic lateral sclerosis , 2012, Journal of Neurology, Neurosurgery & Psychiatry.
[20] Nick C Fox,et al. Longitudinal neuroimaging and neuropsychological profiles of frontotemporal dementia with C9ORF72 expansions , 2012, Alzheimer's Research & Therapy.
[21] John L. Robinson,et al. Pattern of ubiquilin pathology in ALS and FTLD indicates presence of C9ORF72 hexanucleotide expansion , 2012, Acta Neuropathologica.
[22] A. Al-Chalabi,et al. Cognitive and clinical characteristics of patients with amyotrophic lateral sclerosis carrying a C9orf72 repeat expansion: a population-based cohort study , 2012, The Lancet Neurology.
[23] J. Hardy,et al. Clinico-pathological features in amyotrophic lateral sclerosis with expansions in C9ORF72. , 2012, Brain : a journal of neurology.
[24] C. Jack,et al. Neuroimaging signatures of frontotemporal dementia genetics: C9ORF72, tau, progranulin and sporadics , 2012, Brain : a journal of neurology.
[25] Nick C Fox,et al. Frontotemporal dementia with the C9ORF72 hexanucleotide repeat expansion: clinical, neuroanatomical and neuropathological features , 2012, Alzheimer's & Dementia.
[26] Murray Grossman,et al. The Philadelphia Brief Assessment of Cognition (PBAC): A Validated Screening Measure for Dementia , 2011, The Clinical neuropsychologist.
[27] David Heckerman,et al. A Hexanucleotide Repeat Expansion in C9ORF72 Is the Cause of Chromosome 9p21-Linked ALS-FTD , 2011, Neuron.
[28] Bruce L. Miller,et al. Expanded GGGGCC Hexanucleotide Repeat in Noncoding Region of C9ORF72 Causes Chromosome 9p-Linked FTD and ALS , 2011, Neuron.
[29] Nick C Fox,et al. Sensitivity of revised diagnostic criteria for the behavioural variant of frontotemporal dementia. , 2011, Brain : a journal of neurology.
[30] B. Miller,et al. Classification of primary progressive aphasia and its variants , 2011, Neurology.
[31] Arno Klein,et al. A reproducible evaluation of ANTs similarity metric performance in brain image registration , 2011, NeuroImage.
[32] B. Boeve,et al. Clinical, neuroimaging and neuropathological features of a new chromosome 9p-linked FTD-ALS family , 2010, Journal of Neurology, Neurosurgery & Psychiatry.
[33] Jennifer L. Whitwell,et al. MRI Correlates of Protein Deposition and Disease Severity in Postmortem Frontotemporal Lobar Degeneration , 2009, Neurodegenerative Diseases.
[34] M. Freedman,et al. Consensus criteria for the diagnosis of frontotemporal cognitive and behavioural syndromes in amyotrophic lateral sclerosis , 2009, Amyotrophic lateral sclerosis : official publication of the World Federation of Neurology Research Group on Motor Neuron Diseases.
[35] Brian B. Avants,et al. Symmetric diffeomorphic image registration with cross-correlation: Evaluating automated labeling of elderly and neurodegenerative brain , 2008, Medical Image Anal..
[36] Cheryl L. Dahle,et al. Regional brain changes in aging healthy adults: general trends, individual differences and modifiers. , 2005, Cerebral cortex.
[37] N. Tzourio-Mazoyer,et al. Automated Anatomical Labeling of Activations in SPM Using a Macroscopic Anatomical Parcellation of the MNI MRI Single-Subject Brain , 2002, NeuroImage.
[38] Thomas E. Nichols,et al. Nonparametric permutation tests for functional neuroimaging: A primer with examples , 2002, Human brain mapping.
[39] M. Grossman,et al. Hypermethylation of repeat expanded C9orf72 is a clinical and molecular disease modifier , 2014, Acta Neuropathologica.