The IKK/NF-κB signaling pathway requires Morgana to drive breast cancer metastasis
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P. Provero | L. Silengo | F. Altruda | I. Castellano | L. Conti | E. Turco | M. Mello-Grand | G. Chiorino | F. Cavallo | S. Oliviero | A. Křepelová | G. Tarone | M. Brancaccio | L. Annaratone | A. Morotti | F. Fusella | L. Seclì | S. Rocca | E. Moiso | V. Singh | C. Rubinetto | Elena Busso | Vijay Singh
[1] M. Delgado-Rodríguez,et al. Systematic review and meta-analysis. , 2017, Medicina intensiva.
[2] Thomas R. Cox,et al. Pre-metastatic niches: organ-specific homes for metastases , 2017, Nature Reviews Cancer.
[3] Lei Wang,et al. NRF2 promotes breast cancer cell proliferation and metastasis by increasing RhoA/ROCK pathway signal transduction , 2016, Oncotarget.
[4] J. Koblinski,et al. NSG Mice Provide a Better Spontaneous Model of Breast Cancer Metastasis than Athymic (Nude) Mice , 2016, PloS one.
[5] T. Kuijpers,et al. Neutrophils in cancer , 2016, Immunological reviews.
[6] B. Segal,et al. Neutrophils in the tumor microenvironment: trying to heal the wound that cannot heal , 2016, Immunological reviews.
[7] Koichi S. Kobayashi,et al. CITA/NLRC5: A critical transcriptional regulator of MHC class I gene expression , 2016, BioFactors.
[8] K. E. Visser,et al. Neutrophils in cancer: neutral no more , 2016, Nature Reviews Cancer.
[9] L. Que,et al. A Protocol for the Comprehensive Flow Cytometric Analysis of Immune Cells in Normal and Inflamed Murine Non-Lymphoid Tissues , 2016, PloS one.
[10] H. Cai,et al. Curcumin inhibits LPA-induced invasion by attenuating RhoA/ROCK/MMPs pathway in MCF7 breast cancer cells , 2016, Clinical and Experimental Medicine.
[11] Lewis L. Lanier,et al. NK cells and cancer: you can teach innate cells new tricks , 2015, Nature Reviews Cancer.
[12] I. Malanchi,et al. Neutrophils support lung colonization of metastasis-initiating breast cancer cells , 2015, Nature.
[13] Lekhana Bhandary,et al. Molecular Pathways: New Signaling Considerations When Targeting Cytoskeletal Balance to Reduce Tumor Growth , 2015, Clinical Cancer Research.
[14] M. Brancaccio,et al. The double face of Morgana in tumorigenesis , 2015, Oncotarget.
[15] Jian Huang,et al. NF-κB Expression and Outcomes in Solid Tumors , 2015, Medicine.
[16] P. Pandolfi,et al. Morgana acts as an oncosuppressor in chronic myeloid leukemia. , 2015, Blood.
[17] J. Jonkers,et al. IL17-producing γδ T cells and neutrophils conspire to promote breast cancer metastasis , 2015, Nature.
[18] Travis J Cohoon,et al. Targeting an IKBKE cytokine network impairs triple-negative breast cancer growth. , 2014, The Journal of clinical investigation.
[19] P. Pandolfi,et al. Morgana acts as a proto‐oncogene through inhibition of a ROCK–PTEN pathway , 2014, The Journal of pathology.
[20] C. Lim,et al. DEAD-box helicase DP103 defines metastatic potential of human breast cancers. , 2014, The Journal of clinical investigation.
[21] Inder M. Verma,et al. NF-κB, an Active Player in Human Cancers , 2014, Cancer Immunology Research.
[22] R. Weinberg,et al. The tumour-induced systemic environment as a critical regulator of cancer progression and metastasis , 2014, Nature Cell Biology.
[23] P. Musiani,et al. Multiple Roles of Perforin in Hampering ERBB-2 (Her-2/neu) Carcinogenesis in Transgenic Male Mice , 2014, The Journal of Immunology.
[24] Derek C. Radisky,et al. Tumor cell-produced matrix metalloproteinase 9 (MMP-9) drives malignant progression and metastasis of basal-like triple negative breast cancer , 2014, Oncotarget.
[25] Li Ma,et al. α-catenin acts as a tumor suppressor in E-cadherin-negative basal-like breast cancer by inhibiting NF-κB signaling , 2014, Nature Cell Biology.
[26] Claus Scheidereit,et al. The IκB kinase complex in NF‐κB regulation and beyond , 2014, EMBO reports.
[27] M. Ahmadian,et al. Rho-kinase: regulation, (dys)function, and inhibition , 2013, Biological chemistry.
[28] H. Schreiber,et al. Innate and adaptive immune cells in the tumor microenvironment , 2013, Nature Immunology.
[29] Robert S. Kerbel,et al. Differential Post-Surgical Metastasis and Survival in SCID, NOD-SCID and NOD-SCID-IL-2Rγnull Mice with Parental and Subline Variants of Human Breast Cancer: Implications for Host Defense Mechanisms Regulating Metastasis , 2013, PloS one.
[30] J. Schmid,et al. The complexity of NF-κB signaling in inflammation and cancer , 2013, Molecular Cancer.
[31] J. Hahn,et al. Dynamic Nucleotide-dependent Interactions of Cysteine- and Histidine-rich Domain (CHORD)-containing Hsp90 Cochaperones Chp-1 and Melusin with Cochaperones PP5 and Sgt1* , 2012, The Journal of Biological Chemistry.
[32] A. Thotakura,et al. The nuclear factor kappa B signaling pathway: integrating metabolism with inflammation. , 2012, Trends in cell biology.
[33] Mary Goldman,et al. The UCSC Cancer Genomics Browser: update 2015 , 2014, Nucleic Acids Res..
[34] A. Bertero,et al. Morgana and melusin: Two fairies chaperoning signal transduction , 2011, Cell cycle.
[35] L. Silengo,et al. ERK1/2 activation in heart is controlled by melusin, focal adhesion kinase and the scaffold protein IQGAP1 , 2011, Journal of Cell Science.
[36] Joshua M. Stuart,et al. Subtype and pathway specific responses to anticancer compounds in breast cancer , 2011, Proceedings of the National Academy of Sciences.
[37] Robert A. Weinberg,et al. Tumor Metastasis: Molecular Insights and Evolving Paradigms , 2011, Cell.
[38] M. Schmidt-Supprian,et al. NF-κB Essential Modulator (NEMO) Interaction with Linear and Lys-63 Ubiquitin Chains Contributes to NF-κB Activation* , 2011, The Journal of Biological Chemistry.
[39] M. Lisanti,et al. The canonical NF-kappaB pathway governs mammary tumorigenesis in transgenic mice and tumor stem cell expansion. , 2010, Cancer research.
[40] Mary Goldman,et al. The UCSC cancer genomics browser: update 2011 , 2010, Nucleic Acids Res..
[41] J. Kuźnicki,et al. Morgana/CHP-1 is a novel chaperone able to protect cells from stress. , 2010, Biochimica et biophysica acta.
[42] A. S. Shifera. Proteins that bind to IKKgamma (NEMO) and down-regulate the activation of NF-kappaB. , 2010, Biochemical and biophysical research communications.
[43] David Haussler,et al. Inference of patient-specific pathway activities from multi-dimensional cancer genomics data using PARADIGM , 2010, Bioinform..
[44] P. Pandolfi,et al. Morgana/chp-1, a ROCK inhibitor involved in centrosome duplication and tumorigenesis. , 2010, Developmental cell.
[45] A. Israël. The IKK complex, a central regulator of NF-kappaB activation. , 2010, Cold Spring Harbor perspectives in biology.
[46] J. Simon,et al. A Proteomic Investigation of Ligand-dependent HSP90 Complexes Reveals CHORDC1 as a Novel ADP-dependent HSP90-interacting Protein* , 2009, Molecular & Cellular Proteomics.
[47] J. Inoue,et al. Constitutive activation of nuclear factor‐κB is preferentially involved in the proliferation of basal‐like subtype breast cancer cell lines , 2009, Cancer science.
[48] Ting Wang,et al. The UCSC Cancer Genomics Browser , 2009, Nature Methods.
[49] W. Born,et al. IL‐17‐producing γδ T cells , 2009, European Journal of Immunology.
[50] S. Narumiya,et al. Rho signaling, ROCK and mDia1, in transformation, metastasis and invasion , 2009, Cancer and Metastasis Reviews.
[51] T. Suuronen,et al. Innate immunity meets with cellular stress at the IKK complex: regulation of the IKK complex by HSP70 and HSP90. , 2008, Immunology letters.
[52] Yuliang Wu,et al. Detecting protein–protein interactions by far western blotting , 2007, Nature Protocols.
[53] M. Hinz,et al. Signal Responsiveness of IκB Kinases Is Determined by Cdc37-assisted Transient Interaction with Hsp90* , 2007, Journal of Biological Chemistry.
[54] G. Courtois,et al. Posttranslational modifications of NEMO and its partners in NF-κB signaling , 2006 .
[55] Claus Scheidereit,et al. IκB kinase complexes: gateways to NF-κB activation and transcription , 2006, Oncogene.
[56] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[57] J. Hahn. Regulation of Nod1 by Hsp90 chaperone complex , 2005, FEBS letters.
[58] S. Luo,et al. Mammalian CHORD‐containing protein 1 is a novel heat shock protein 90‐interacting protein , 2005, FEBS letters.
[59] A. Shevchenko,et al. Activation of Transcription Factor NF-κB Requires ELKS, an IκB Kinase Regulatory Subunit , 2004, Science.
[60] L. Silengo,et al. Chp‐1 and melusin, two CHORD containing proteins in vertebrates , 2003, FEBS letters.
[61] E. Sahai,et al. ERK-MAPK signaling coordinately regulates activity of Rac1 and RhoA for tumor cell motility. , 2003, Cancer cell.
[62] M. Daly,et al. PGC-1α-responsive genes involved in oxidative phosphorylation are coordinately downregulated in human diabetes , 2003, Nature Genetics.
[63] D. Goeddel,et al. TNF-induced recruitment and activation of the IKK complex require Cdc37 and Hsp90. , 2002, Molecular cell.
[64] H. Koh,et al. Akt/PKB promotes cancer cell invasion via increased motility and metalloproteinase production. , 2001, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[65] A. E. Rogers,et al. Aberrant nuclear factor-kappaB/Rel expression and the pathogenesis of breast cancer. , 1997, The Journal of clinical investigation.
[66] R. Fridman,et al. Assessment of gelatinases (MMP-2 and MMP-9) by gelatin zymography. , 2012, Methods in molecular biology.
[67] C. Scheidereit. IkappaB kinase complexes: gateways to NF-kappaB activation and transcription. , 2006, Oncogene.
[68] A. Hoffmann,et al. Circuitry of nuclear factor kappaB signaling. , 2006, Immunological reviews.
[69] G. Courtois,et al. Posttranslational modifications of NEMO and its partners in NF-kappaB signaling. , 2006, Trends in cell biology.
[70] M. Merville,et al. Phosphorylation of NF-kappaB and IkappaB proteins: implications in cancer and inflammation. , 2005, Trends in biochemical sciences.
[71] M. Merville,et al. Phosphorylation of NF-κB and IκB proteins: implications in cancer and inflammation , 2005 .
[72] C. Scheidereit,et al. Requirement of Hsp90 activity for IkappaB kinase (IKK) biosynthesis and for constitutive and inducible IKK and NF-kappaB activation. , 2004, Oncogene.