Synaptic Microcircuits in the Barrel Cortex

An elementary feature of sensory cortices is thought to be their organisation into functional signal-processing units called ‘cortical columns’. These elementary units process sensory information arriving from peripheral receptors; they are vertically oriented throughout all cortical layers and contain several thousands of excitatory and inhibitory synaptic connections. To understand how sensory signals are transformed into electrical activity in the neocortex it is necessary to elucidate the spatial-temporal dynamics of cortical signal processing and the underlying neurons and synaptic ‘microcircuits’.

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