Activation of BAD by Therapeutic Inhibition of Epidermal Growth Factor Receptor and Transactivation by Insulin-like Growth Factor Receptor*
暂无分享,去创建一个
S. Korsmeyer | M. O'hare | C. Streuli | Pengbo Wang | A. Ranger | A. Gilmore | A. Wakeling | N. Bundred | A. Valentijn | Pengbo Wang
[1] F. Peruzzi,et al. Anti-apoptotic Signaling of the Insulin-like Growth Factor-I Receptor through Mitochondrial Translocation of c-Raf and Nedd4* , 2001, The Journal of Biological Chemistry.
[2] G. Evan,et al. Proliferation, cell cycle and apoptosis in cancer , 2001, Nature.
[3] B. Ursø,et al. Comparison of anti-apoptotic signalling by the insulin receptor and IGF-I receptor in preadipocytes and adipocytes. , 2001, Cellular signalling.
[4] O. Bernard,et al. Dominant-Negative c-Jun Promotes Neuronal Survival by Reducing BIM Expression and Inhibiting Mitochondrial Cytochrome c Release , 2001, Neuron.
[5] D. Slamon,et al. Blockade of growth factor receptors in ductal carcinoma in situ inhibits epithelial proliferation , 2001, The British journal of surgery.
[6] Kam Y. J. Zhang,et al. Antimycin A mimics a cell-death-inducing Bcl-2 homology domain 3 , 2001, Nature Cell Biology.
[7] T. Mitchison,et al. Identification of small-molecule inhibitors of interaction between the BH3 domain and Bcl-xL , 2001, Nature Cell Biology.
[8] W. Gerald,et al. Inactivation of the apoptosis effector Apaf-1 in malignant melanoma , 2001, Nature.
[9] J. Gutkind,et al. Signaling from E-cadherins to the MAPK Pathway by the Recruitment and Activation of Epidermal Growth Factor Receptors upon Cell-Cell Contact Formation* , 2000, The Journal of Biological Chemistry.
[10] Ming Li,et al. Stimulation of the Mitogen-activated Protein Kinase Cascade and Tyrosine Phosphorylation of the Epidermal Growth Factor Receptor by Hepatopoietin* , 2000, The Journal of Biological Chemistry.
[11] M. Kris,et al. Efficacy of cytotoxic agents against human tumor xenografts is markedly enhanced by coadministration of ZD1839 (Iressa), an inhibitor of EGFR tyrosine kinase. , 2000, Clinical cancer research : an official journal of the American Association for Cancer Research.
[12] D. Livingston,et al. In search of the tumour-suppressor functions of BRCA1 and BRCA2 , 2000, Nature.
[13] Y. Sagara,et al. Co‐expression of epidermal growth factor receptor and transforming growth factor‐α predicts worse prognosis in breast‐cancer patients , 2000, International journal of cancer.
[14] J. Levine,et al. Surfing the p53 network , 2000, Nature.
[15] Rachel L. Allen,et al. Defying death after DNA damage , 2000, Nature.
[16] T. Rohan,et al. Role of the insulin-like growth factor family in cancer development and progression. , 2000, Journal of the National Cancer Institute.
[17] H. Ruan,et al. BAD Ser-155 Phosphorylation Regulates BAD/Bcl-XL Interaction and Cell Survival* , 2000, The Journal of Biological Chemistry.
[18] T. Chittenden,et al. Growth Factors Inactivate the Cell Death Promoter BAD by Phosphorylation of Its BH3 Domain on Ser155 * , 2000, The Journal of Biological Chemistry.
[19] K. L. Pierce,et al. Transactivation of the EGF Receptor Mediates IGF-1-stimulated Shc Phosphorylation and ERK1/2 Activation in COS-7 Cells* , 2000, The Journal of Biological Chemistry.
[20] Monilola A. Olayioye,et al. The ErbB signaling network: receptor heterodimerization in development and cancer , 2000, The EMBO journal.
[21] T. Taniguchi,et al. Noxa, a BH3-only member of the Bcl-2 family and candidate mediator of p53-induced apoptosis. , 2000, Science.
[22] R. Lefkowitz,et al. The β2-Adrenergic Receptor Mediates Extracellular Signal-regulated Kinase Activation via Assembly of a Multi-receptor Complex with the Epidermal Growth Factor Receptor* , 2000, The Journal of Biological Chemistry.
[23] D. Yee,et al. Tyrosine kinase signalling in breast cancer: Insulin-like growth factors and their receptors in breast cancer , 2000, Breast Cancer Research.
[24] Gerard I. Evan,et al. The coordinate release of cytochrome c during apoptosis is rapid, complete and kinetically invariant , 2000, Nature Cell Biology.
[25] J. Blenis,et al. Rsk1 mediates a MEK–MAP kinase cell survival signal , 2000, Current Biology.
[26] G. Mills,et al. Regulation of BAD phosphorylation at serine 112 by the Ras-mitogen-activated protein kinase pathway , 1999, Oncogene.
[27] S. R. Datta,et al. Cell survival promoted by the Ras-MAPK signaling pathway by transcription-dependent and -independent mechanisms. , 1999, Science.
[28] M. Scheid,et al. Regulation of Bad Phosphorylation and Association with Bcl-xL by the MAPK/Erk Kinase* , 1999, The Journal of Biological Chemistry.
[29] B. Calabretta,et al. Multiple Signaling Pathways of the Insulin-Like Growth Factor 1 Receptor in Protection from Apoptosis , 1999, Molecular and Cellular Biology.
[30] N. Robert,et al. Multinational study of the efficacy and safety of humanized anti-HER2 monoclonal antibody in women who have HER2-overexpressing metastatic breast cancer that has progressed after chemotherapy for metastatic disease. , 1999, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[31] S. Korsmeyer,et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis , 1999, Nature.
[32] C. Streuli,et al. Extracellular Matrix Selectively Modulates the Response of Mammary Epithelial Cells to Different Soluble Signaling Ligands* , 1999, The Journal of Biological Chemistry.
[33] S. Korsmeyer,et al. BCL-2 family members and the mitochondria in apoptosis. , 1999, Genes & development.
[34] David C. Lee,et al. Targeted inactivation of the EGF and amphiregulin genes reveals distinct roles for EGF receptor ligands in mouse mammary gland development. , 1999, Development.
[35] J. Woodburn,et al. The epidermal growth factor receptor and its inhibition in cancer therapy. , 1999, Pharmacology & therapeutics.
[36] D. W. Fry,et al. Inhibition of the epidermal growth factor receptor family of tyrosine kinases as an approach to cancer chemotherapy: progression from reversible to irreversible inhibitors. , 1999 .
[37] Susan S. Taylor,et al. Phosphorylation and inactivation of BAD by mitochondria-anchored protein kinase A. , 1999, Molecular cell.
[38] C. Dive,et al. Extracellular Matrix Regulates Apoptosis in Mammary Epithelium through a Control on Insulin Signaling , 1999, The Journal of cell biology.
[39] Z. Werb,et al. Signaling through the stromal epidermal growth factor receptor is necessary for mammary ductal development. , 1999, Development.
[40] S. Lowe,et al. Apoptosis and therapy , 1999, The Journal of pathology.
[41] R. Fåhraeus,et al. New approaches to cancer therapies , 1999, The Journal of pathology.
[42] L. Silengo,et al. Integrins induce activation of EGF receptor: role in MAP kinase induction and adhesion‐dependent cell survival , 1998, The EMBO journal.
[43] H. Kawakatsu,et al. Calcium-dependent Epidermal Growth Factor Receptor Transactivation Mediates the Angiotensin II-induced Mitogen-activated Protein Kinase Activation in Vascular Smooth Muscle Cells* , 1998, The Journal of Biological Chemistry.
[44] J. Mendelsohn. Epidermal growth factor receptor inhibition by a monoclonal antibody as anticancer therapy. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.
[45] A. Howell,et al. Investigation of mammary epithelial cell‐bone marrow stroma interactions using primary human cell culture as a model of metastasis , 1997, International journal of cancer.
[46] L. Peso,et al. Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt. , 1997, Science.
[47] S. R. Datta,et al. Akt Phosphorylation of BAD Couples Survival Signals to the Cell-Intrinsic Death Machinery , 1997, Cell.
[48] S. Korsmeyer,et al. BH3 Domain of BAD Is Required for Heterodimerization with BCL-XL and Pro-apoptotic Activity* , 1997, The Journal of Biological Chemistry.
[49] David R. Kaplan,et al. Regulation of Neuronal Survival by the Serine-Threonine Protein Kinase Akt , 1997, Science.
[50] D. Leroith,et al. Insulin-like Growth Factor 1 Inhibits Apoptosis Using the Phosphatidylinositol 3′-Kinase and Mitogen-activated Protein Kinase Pathways* , 1997, The Journal of Biological Chemistry.
[51] Elizabeth Yang,et al. Serine Phosphorylation of Death Agonist BAD in Response to Survival Factor Results in Binding to 14-3-3 Not BCL-XL , 1996, Cell.
[52] J. Hickman,et al. Requirement of basement membrane for the suppression of programmed cell death in mammary epithelium. , 1996, Journal of cell science.
[53] L. Cheng,et al. Programmed cell death by default in embryonic cells, fibroblasts, and cancer cells. , 1995, Molecular biology of the cell.
[54] N. Normanno,et al. Epidermal growth factor-related peptides and their receptors in human malignancies. , 1995, Critical reviews in oncology/hematology.
[55] S. Korsmeyer,et al. Bad, a heterodimeric partner for Bcl-xL and Bcl-2, displaces bax and promotes cell death , 1995, Cell.
[56] J. Blenis,et al. Insulin receptor substrate-1 mediates phosphatidylinositol 3'-kinase and p70S6k signaling during insulin, insulin-like growth factor-1, and interleukin-4 stimulation. , 1994, The Journal of biological chemistry.
[57] S. Lowe,et al. p53-Dependent apoptosis suppresses tumor growth and progression in vivo , 1994, Cell.
[58] M. White,et al. The IRS-1 signaling system. , 1994, Trends in biochemical sciences.
[59] J. Olefsky,et al. Shc is the predominant signaling molecule coupling insulin receptors to activation of guanine nucleotide releasing factor and p21ras-GTP formation. , 1994, The Journal of biological chemistry.
[60] J. Hickman,et al. Apoptosis induced by anticancer drugs , 1992, Cancer and Metastasis Reviews.
[61] F. Kittrell,et al. Development of mammary preneoplasias in vivo from mouse mammary epithelial cell lines in vitro. , 1992, Cancer research.
[62] J. Hickman,et al. Drug-target interactions: only the first step in the commitment to a programmed cell death? , 1991, British Journal of Cancer.
[63] J. L. Bos,et al. ras oncogenes in human cancer: a review. , 1989, Cancer research.
[64] N. Normanno,et al. The role of amphiregulin in breast cancer , 2004, Breast Cancer Research and Treatment.
[65] V. Kataja,et al. Prognostic significance of TGF-α expression in breast cancer , 1996 .