Visual disengagement in the infant siblings of children with an autism spectrum disorder (ASD)

Children with autism spectrum disorders (ASDs) are impaired in visually disengaging attention in both social and non-social contexts. These impairments may, in subtler form, also affect the infant siblings of children with ASD (ASD-sibs). We investigated patterns of visual attention (gazing) in 6-month-old ASD-sibs (n = 17) and the siblings of typically developing children (COMP-sibs: n =17) during the Face-to-Face/Still-Face Protocol (FFSF), in which parents are sequentially responsive, non-responsive, and responsive to their infants. Throughout the protocol, ASD-sibs shifted their gaze to and from their parents' faces less frequently than did COMP-sibs. The mean durations of ASD-sibs' gazes away from their parents' faces were longer than those of COMP-sibs. ASD-sibs and COMP-sibs did not differ in the mean durations of gazes at their parents' faces. In sum, ASD-sibs showed no deficits in visual interest to their parents' faces, but greater interest than COMP-sibs in non-face stimuli.

[1]  G. Dawson,et al.  Social stimulation and joint attention in young autistic children , 1992, Journal of abnormal child psychology.

[2]  T. Brazelton,et al.  The infant's response to entrapment between contradictory messages in face-to-face interaction. , 1978, Journal of the American Academy of Child Psychiatry.

[3]  Edward G. Carr,et al.  Joint Attention in Children With Autism , 2004 .

[4]  J. Brian,et al.  Behavioral manifestations of autism in the first year of life , 2005, International Journal of Developmental Neuroscience.

[5]  G. Baranek.  Autism During Infancy: A Retrospective Video Analysis of Sensory-Motor and Social Behaviors at 9–12 Months of Age , 1999, Journal of autism and developmental disorders.

[6]  M. Spence,et al.  Brief Report: Early Social Communication Behaviors in the Younger Siblings of Children with Autism , 2005, Journal of autism and developmental disorders.

[7]  B. Tabachnick,et al.  Using Multivariate Statistics , 1983 .

[8]  L. Adamson,et al.  The Still Face: A History of a Shared Experimental Paradigm , 2003 .

[9]  Susan E. Bryson,et al.  Visual-spatial orienting in autism , 1996, Journal of autism and developmental disorders.

[10]  S. Baron-Cohen,et al.  The development of siblings of children with autism at 4 and 14 months: social engagement, communication, and cognition. , 2006, Journal of child psychology and psychiatry, and allied disciplines.

[11]  A. Couteur,et al.  Autism Diagnostic Interview-Revised: A revised version of a diagnostic interview for caregivers of individuals with possible pervasive developmental disorders , 1994, Journal of autism and developmental disorders.

[12]  S. Bryson,et al.  Impaired disengagement of attention in young children with autism. , 2004, Journal of child psychology and psychiatry, and allied disciplines.

[13]  G. Dawson,et al.  Defining the broader phenotype of autism: Genetic, brain, and behavioral perspectives , 2002, Development and Psychopathology.

[14]  G. Dawson,et al.  Early recognition of children with autism: A study of first birthday home videotapes , 1994, Journal of autism and developmental disorders.

[15]  Michael Morales,et al.  Responding to Joint Attention Across the 6- Through 24-Month Age Period and Early Language Acquisition , 2000 .

[16]  P. Mundy,et al.  Social interactions of autistic, mentally retarded and normal children and their caregivers. , 1986, Journal of child psychology and psychiatry, and allied disciplines.

[17]  J. Ducharme,et al.  Variables influencing stimulus overselectivity and "tunnel vision" in developmentally delayed children. , 1987, American journal of mental deficiency.

[18]  E. Fombonne,et al.  The epidemiology of autism: a review , 1999, Psychological Medicine.

[19]  C. Lord.  Autism diagnostic observation schedule : ADOS manual , 2003 .

[20]  P. Mundy,et al.  Defining the social deficits of autism: the contribution of non-verbal communication measures. , 1986, Journal of child psychology and psychiatry, and allied disciplines.

[21]  Susan E. Bryson,et al.  Visual orienting deficits in high-functioning people with autism , 1993, Journal of autism and developmental disorders.

[22]  S. Rogers,et al.  Visual Fixation Patterns during Reciprocal Social Interaction Distinguish a Subgroup of 6-Month-Old Infants At-Risk for Autism from Comparison Infants , 2007, Journal of autism and developmental disorders.

[23]  L. Schreibman,et al.  Stimulus overselectivity of autistic children in a two stimulus situation. , 1971, Behaviour research and therapy.

[24]  D. Messinger,et al.  Early Social and Emotional Communication in the Infant Siblings of Children with Autism Spectrum Disorders: An Examination of the Broad Phenotype , 2007, Journal of autism and developmental disorders.

[25]  M. Sigman,et al.  The Development of Young Siblings of Children with Autism from 4 to 54 Months , 2007, Journal of autism and developmental disorders.

[26]  P. Mundy,et al.  Individual differences and the development of joint attention in infancy. , 2007, Child development.

[27]  G. Dawson,et al.  Brief Report: Recognition of Autism Spectrum Disorder Before One Year of Age: A Retrospective Study Based on Home Videotapes , 2000, Journal of autism and developmental disorders.

[28]  A. Meltzoff,et al.  Children with Autism Fail to Orient to Naturally Occurring Social Stimuli , 1998, Journal of autism and developmental disorders.

[29]  S. Bryson,et al.  AUTISTIC SPECTRUM DISORDERS: CAUSAL MECHANISMS AND RECENT FINDINGS ON ATTENTION AND EMOTION , 2004 .

[30]  M. Rothbart,et al.  Self-regulation and emotion in infancy. , 1992, New directions for child development.

[31]  Daniel S. Messinger,et al.  Give and Take: The Development of Conventional Infant Gestures. , 1998 .

[32]  A Pickles,et al.  Autism screening questionnaire: Diagnostic validity , 1999, British Journal of Psychiatry.

[33]  The International Meeting for Autism Research , 2009 .

[34]  S. Roux,et al.  [Early signs of autism and family films: a new study by informed evaluators and those unaware of the diagnosis]. , 2000, L'Encephale.

[35]  Ruth A. Carper,et al.  Neuroanatomic contributions to slowed orienting of attention in children with autism. , 1999, Brain research. Cognitive brain research.

[36]  S. Baird,et al.  Identifying Early Indicators for Autism in Self-Regulation Difficulties , 2005 .

[37]  J. Malvy,et al.  Signes précoces de l'autisme et films familiaux , 1997 .

[38]  G. Dawson,et al.  Early social attention impairments in autism: social orienting, joint attention, and attention to distress. , 2004, Developmental psychology.

[39]  R. Landa,et al.  Development in infants with autism spectrum disorders: a prospective study. , 2006, Journal of child psychology and psychiatry, and allied disciplines.

[40]  C. Lajonchere,et al.  Autistic social impairment in the siblings of children with pervasive developmental disorders. , 2006, The American journal of psychiatry.