LIFR inhibition enhances the therapeutic efficacy of HDAC inhibitors in triple negative breast cancer
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A. Brenner | G. Raj | Yidong Chen | Hui Yan | Zhenming Xu | R. Tekmal | R. Vadlamudi | M. Rao | V. Kaklamani | Xiaonan Li | H. Nair | Gangadhara R. Sareddy | G. Ahmed | G. Sareddy | Weiwei Tang | Yi Zou | B. Santhamma | Swapna Konda | S. Viswanadhapalli | K. Nickisch | Zexuan Liu | B. Ebrahimi | Mengxing Li | Yiliao Luo | Junhao Liu | Kristin A Altwegg | Uday P. Pratap | Behnam Ebrahimi
[1] T. Hunter,et al. An engineered ligand trap inhibits leukemia inhibitory factor as pancreatic cancer treatment strategy , 2021, Communications Biology.
[2] Yi-Wen Chang,et al. STAT3 phosphorylation at Ser727 and Tyr705 differentially regulates the EMT–MET switch and cancer metastasis , 2020, Oncogene.
[3] R. Jiang,et al. The circRNA circSEPT9 mediated by E2F1 and EIF4A3 facilitates the carcinogenesis and development of triple-negative breast cancer , 2020, Molecular Cancer.
[4] E. Collisson,et al. Blockade of leukemia inhibitory factor as a therapeutic approach to KRAS driven pancreatic cancer , 2019, Nature Communications.
[5] Kam Y. J. Zhang,et al. EC359: A First-in-Class Small-Molecule Inhibitor for Targeting Oncogenic LIFR Signaling in Triple-Negative Breast Cancer , 2019, Molecular Cancer Therapeutics.
[6] Galina A. Erikson,et al. Targeting LIF-mediated paracrine interaction for pancreatic cancer therapy and monitoring , 2019, Nature.
[7] L. Orlando,et al. Targeting triple negative breast cancer with histone deacetylase inhibitors , 2017, Expert opinion on investigational drugs.
[8] N. Nikiteas,et al. Histone Deacetylases as New Therapeutic Targets in Triple-negative Breast Cancer: Progress and Promises. , 2017, Cancer genomics & proteomics.
[9] G. Raj,et al. Estrogen receptor coregulator binding modulators (ERXs) effectively target estrogen receptor positive human breast cancers , 2017, eLife.
[10] Katherine C. Sexton,et al. Genomic regulation of invasion by STAT3 in triple negative breast cancer , 2016, Oncotarget.
[11] Min Huang,et al. Feedback Activation of Leukemia Inhibitory Factor Receptor Limits Response to Histone Deacetylase Inhibitors in Breast Cancer. , 2016, Cancer cell.
[12] Joshua R. Johnson,et al. Induction of LIFR confers a dormancy phenotype in breast cancer cells disseminated to the bone marrow , 2016, Nature Cell Biology.
[13] M. Arock,et al. The increasing roles of epigenetics in breast cancer: Implications for pathogenicity, biomarkers, prevention and treatment , 2015, International journal of cancer.
[14] B. Liu,et al. Leukemia inhibitory factor promotes tumor growth and metastasis in human osteosarcoma via activating STAT3 , 2015, APMIS : acta pathologica, microbiologica, et immunologica Scandinavica.
[15] A. Floreani,et al. Leukemia inhibitory factor protects cholangiocarcinoma cells from drug-induced apoptosis via a PI3K/AKT-dependent Mcl-1 activation , 2015, Oncotarget.
[16] Wenwei Hu,et al. LIF is a new p53 negative regulator. , 2015, Journal of nature and science.
[17] Rory Stark,et al. Progesterone receptor modulates estrogen receptor-α action in breast cancer , 2015, Nature.
[18] Wenwei Hu,et al. HIF-2α mediates hypoxia-induced LIF expression in human colorectal cancer cells , 2015, Oncotarget.
[19] C. Caldas,et al. Progesterone receptor modulates ERa action in breast cancer , 2015 .
[20] K. Young,et al. LIF negatively regulates tumor suppressor p53 through Stat3/ID1/MDM2 in colorectal cancers , 2014, Nature Communications.
[21] Paul Theodor Pyl,et al. HTSeq—a Python framework to work with high-throughput sequencing data , 2014, bioRxiv.
[22] M. Ferrari,et al. XBP1 Promotes Triple Negative Breast Cancer By Controlling the HIF1 α Pathway , 2014, Nature.
[23] Zhen Liu,et al. LIF promotes tumorigenesis and metastasis of breast cancer through the AKT-mTOR pathway , 2014, Oncotarget.
[24] R. Johnstone,et al. New and emerging HDAC inhibitors for cancer treatment. , 2014, The Journal of clinical investigation.
[25] Ying Liang,et al. Leukemia inhibitory factor promotes nasopharyngeal carcinoma progression and radioresistance. , 2013, The Journal of clinical investigation.
[26] A. Bosserhoff,et al. Impact of LIF (leukemia inhibitory factor) expression in malignant melanoma. , 2013, Experimental and molecular pathology.
[27] R. Vadlamudi,et al. PELP1 oncogenic functions involve CARM1 regulation. , 2013, Carcinogenesis.
[28] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumours , 2013 .
[29] Peijing Zhang,et al. LIFR is a breast cancer metastasis suppressor upstream of the Hippo-YAP pathway and a prognostic marker , 2012, Nature Medicine.
[30] Steven J. M. Jones,et al. Comprehensive molecular portraits of human breast tumors , 2012, Nature.
[31] A. Brenner,et al. Therapeutic Significance of Estrogen Receptor β Agonists in Gliomas , 2012, Molecular Cancer Therapeutics.
[32] J. Shin,et al. Epigenetic up-regulation of leukemia inhibitory factor (LIF) gene during the progression to breast cancer , 2011, Molecules and cells.
[33] L. Carey,et al. Triple-negative breast cancer: disease entity or title of convenience? , 2010, Nature Reviews Clinical Oncology.
[34] Jorge S Reis-Filho,et al. Triple-negative breast cancer. , 2010, The New England journal of medicine.
[35] W. Huber,et al. which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. MAnorm: a robust model for quantitative comparison of ChIP-Seq data sets , 2011 .
[36] T. Chou. Drug combination studies and their synergy quantification using the Chou-Talalay method. , 2010, Cancer research.
[37] Lior Pachter,et al. Sequence Analysis , 2020, Definitions.
[38] Debra L Winkeljohn. Triple-negative breast cancer. , 2008, Clinical journal of oncology nursing.
[39] D. Allred,et al. Development of Standard Estrogen and Progesterone Receptor Immunohistochemical Assays for Selection of Patients for Antihormonal Therapy , 2007, Applied immunohistochemistry & molecular morphology : AIMM.
[40] P. Marks,et al. Histone deacetylase inhibitors: molecular mechanisms of action , 2007, Oncogene.
[41] M. Ogawa,et al. Leukemia inhibitory factor functions as a growth factor in pancreas carcinoma cells: Involvement of regulation of LIF and its receptor expression. , 2007, International journal of oncology.
[42] Pablo Tamayo,et al. Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles , 2005, Proceedings of the National Academy of Sciences of the United States of America.
[43] S. Dalton,et al. LIF/STAT3 controls ES cell self-renewal and pluripotency by a Myc-dependent mechanism , 2005, Development.
[44] P. Marks,et al. Histone deacetylases and cancer: causes and therapies , 2001, Nature Reviews Cancer.
[45] S. Melmed,et al. Leukemia-inhibitory factor-neuroimmune modulator of endocrine function. , 2000, Endocrine reviews.
[46] Z. Estrov,et al. Leukemia‐inhibitory factor stimulates breast, kidney and prostate cancer cell proliferation by paracrine and autocrine pathways , 1996, International journal of cancer.
[47] G. Yancopoulos,et al. Association and activation of Jak-Tyk kinases by CNTF-LIF-OSM-IL-6 beta receptor components. , 1994, Science.
[48] D. Metcalf. The leukemia inhibitory factor (LIF). , 1991, International journal of cell cloning.