Stereoblind monkeys have few binocular neurons.

Infant monkeys wore prisms before their eyes, lost binocular neurons from their visual cortex, and were stereoblind to dynamic random dot stereograms. Three years later, the authors recorded from 880 neurons of the V1 and V2 visual cortex and found only 22% binocular neurons as compared with 81% for normal monkeys. These results demonstrate, for the first time in the same subjects, the strong association between cortical binocular neurons and primate stereopsis; show that congenital binocular neurons, once lost, do not recover even with extensive binocular visual experience; and stress the vulnerability of the primate binocular system to abnormal early visual experiences.

[1]  D. Hubel,et al.  Receptive fields of single neurones in the cat's striate cortex , 1959, The Journal of physiology.

[2]  D. Hubel,et al.  Receptive fields, binocular interaction and functional architecture in the cat's visual cortex , 1962, The Journal of physiology.

[3]  B JULESZ,et al.  Binocular Depth Perception without Familiarity Cues , 1964, Science.

[4]  D. Hubel,et al.  Stereoscopic Vision in Macaque Monkey: Cells sensitive to Binocular Depth in Area 18 of the Macaque Monkey Cortex , 1970, Nature.

[5]  B. Julesz Foundations of Cyclopean Perception , 1971 .

[6]  D. Hubel,et al.  Ordered arrangement of orientation columns in monkeys lacking visual experience , 1974, The Journal of comparative neurology.

[7]  R. Blake,et al.  Physiological consequences of unilateral and bilateral eye closure in macaque monkeys: some further observations , 1975, Brain Research.

[8]  J I Nelson,et al.  Globality and stereoscopic fusion in binocular vision. , 1975, Journal of theoretical biology.

[9]  M. Crawford The visual deprivation syndrome. , 1978, Ophthalmology.

[10]  S. Zeki Uniformity and diversity of structure and function in rhesus monkey prestriate visual cortex. , 1978, The Journal of physiology.

[11]  M. Crawford,et al.  Optically induced concomitant strabismus in monkeys. , 1980, Investigative ophthalmology & visual science.

[12]  T. Wiesel The postnatal development of the visual cortex and the influence of environment. , 1982, Bioscience reports.

[13]  L. S. Meharg,et al.  Binocular neurons and binocular function in monkeys and children. , 1983, Investigative ophthalmology & visual science.