First-Order and Higher Order Sequence Learning in Specific Language Impairment

Objective: A core claim of the procedural deficit hypothesis of specific language impairment (SLI) is that the disorder is associated with poor implicit sequence learning. This study investigated whether implicit sequence learning problems in SLI are present for first-order conditional (FOC) and higher order conditional (HOC) sequences. Method: Twenty-five children with SLI and 27 age-matched, nonlanguage-impaired children completed 2 serial reaction time tasks. On 1 version, the sequence to be implicitly learnt comprised a FOC sequence and on the other a HOC sequence. Results: Results showed that the SLI group learned the HOC sequence (&eegr;p2 = .285, p = .005) but not the FOC sequence (&eegr;p2 = .099, p = .118). The control group learned both sequences (FOC &eegr;p2 = .497, HOC &eegr;p2 = .465, ps < .001). Conclusions: The SLI group’s difficulty learning the FOC sequence is consistent with the procedural deficit hypothesis. However, the study provides new evidence that multiple mechanisms may underpin the learning of FOC and HOC sequences.

[1]  Kelly A. Malcolmson,et al.  The role of the striatum in implicit learning: a functional magnetic resonance imaging study , 2005, Neuroreport.

[2]  John O. Willis,et al.  Wechsler Abbreviated Scale of Intelligence , 2014 .

[3]  T. Q. Irigaray,et al.  Intellectual abilities in Alzheimer's disease patients: Contributions from the Wechsler Abbreviated Scale of Intelligence (WASI) , 2010 .

[4]  J. Gabrieli Cognitive neuroscience of human memory. , 1998, Annual review of psychology.

[5]  M. Hasselmo,et al.  The hippocampus as an associator of discontiguous events , 1998, Trends in Neurosciences.

[6]  E. Soetens,et al.  Intact first- and second-order implicit sequence learning in secondary-school-aged children with developmental dyslexia , 2010, Journal of clinical and experimental neuropsychology.

[7]  M. Nissen,et al.  Attentional requirements of learning: Evidence from performance measures , 1987, Cognitive Psychology.

[8]  P. O'Brien,et al.  The appropriateness of analysis of variance and multiple-comparison procedures. , 1983, Biometrics.

[9]  Jared G. Smith,et al.  Impaired higher order implicit sequence learning on the verbal version of the serial reaction time task in patients with Parkinson's disease. , 2004, Neuropsychology.

[10]  Gillian M Clark,et al.  A meta-analysis and meta-regression of serial reaction time task performance in Parkinson's disease. , 2014, Neuropsychology.

[11]  Richard I. Ivry,et al.  Attention and structure in sequence learning. , 1990 .

[12]  Daniel B. Willingham,et al.  On the development of procedural knowledge. , 1989, Journal of experimental psychology. Learning, memory, and cognition.

[13]  Russell A Poldrack,et al.  Sequence Learning What's the Hippocampus to Do? , 2003, Neuron.

[14]  Morten H. Christiansen,et al.  Impaired statistical learning of non-adjacent dependencies in adolescents with specific language impairment , 2014, Front. Psychol..

[15]  H. V. D. Lely,et al.  Wh-Movement in Children with Grammatical SLI: A Test of the RDDR Hypothesis , 2003 .

[16]  M. Ullman,et al.  Neuroscience and Biobehavioral Reviews , 2015 .

[17]  Peder J. Johnson,et al.  Assessing implicit learning with indirect tests: Determining what is learned about sequence structure. , 1994 .

[18]  M. Gluck,et al.  Cortico-striatal contributions to feedback-based learning: converging data from neuroimaging and neuropsychology. , 2004, Brain : a journal of neurology.

[19]  Rand R. Wilcox,et al.  New designs in analysis of variance. , 1987 .

[20]  S. Holm A Simple Sequentially Rejective Multiple Test Procedure , 1979 .

[21]  J. Lum,et al.  Declarative and procedural memory in Danish speaking children with specific language impairment. , 2012, Journal of communication disorders.

[22]  Eric Soetens,et al.  Perceptual or motor learning in SRT tasks with complex sequence structures , 2006, Psychological research.

[23]  Tobias Sommer,et al.  Evidence of Developmental Differences in Implicit Sequence Learning: An fMRI Study of Children and Adults , 2004, Journal of Cognitive Neuroscience.

[24]  M. Ullman,et al.  Verbal declarative memory impairments in specific language impairment are related to working memory deficits , 2015, Brain and Language.

[25]  S. Rauch,et al.  Striatal recruitment during an implicit sequence learning task as measured by functional magnetic resonance imaging , 1997, Human brain mapping.

[26]  T. Meulemans,et al.  Procedural Learning in Specific Language Impairment: Effects of Sequence Complexity , 2013, Journal of the International Neuropsychological Society.

[27]  Richard J. Siegert,et al.  Is implicit sequence learning impaired in schizophrenia? A meta-analysis , 2008, Brain and Cognition.

[28]  T. Meulemans,et al.  Procedural learning across modalities in French-speaking children with specific language impairment , 2014, Applied Psycholinguistics.

[29]  D. C. Howell Statistical methods for psychology, 3rd ed. , 1992 .

[30]  T. Meulemans,et al.  Exploration of Serial Structure Procedural Learning in Children with Language Impairment , 2011, Journal of the International Neuropsychological Society.

[31]  L. Henderson,et al.  Serial reaction time learning and Parkinson's disease: Evidence for a procedural learning deficit , 1995, Neuropsychologia.

[32]  Evan Kidd,et al.  Individual Differences in Statistical Learning Predict Children's Comprehension of Syntax. , 2016, Child development.

[33]  Thomas F Münte,et al.  Implicit Learning is Intact in Adult Developmental Dyslexic Readers: Evidence from the Serial Reaction Time Task and Artificial Grammar Learning , 2006, Journal of clinical and experimental neuropsychology.

[34]  B. Knowlton,et al.  Learning and memory functions of the Basal Ganglia. , 2002, Annual review of neuroscience.

[35]  Scott T. Grafton,et al.  Functional Mapping of Sequence Learning in Normal Humans , 1995, Journal of Cognitive Neuroscience.

[36]  S. Keele,et al.  The cognitive and neural architecture of sequence representation. , 2003, Psychological review.

[37]  Tim Curran,et al.  Higher-Order Associative Learning in Amnesia: Evidence from the Serial Reaction Time Task , 1997, Journal of Cognitive Neuroscience.

[38]  M. Ullman,et al.  Procedural learning deficits in specific language impairment (SLI): A meta-analysis of serial reaction time task performance , 2014, Cortex.

[39]  T. Meulemans,et al.  Procedural visual learning in children with specific language impairment. , 2012, American journal of speech-language pathology.

[40]  C. Stern,et al.  An fMRI Study of the Role of the Medial Temporal Lobe in Implicit and Explicit Sequence Learning , 2003, Neuron.

[41]  O'Brien Pc,et al.  The appropriateness of analysis of variance and multiple-comparison procedures. , 1983 .

[42]  Eric Soetens,et al.  Learning sequence movements in a homogenous sample of patients with Parkinson's disease , 2006, Neuropsychologia.

[43]  Jarrad A. G. Lum,et al.  Procedural and declarative memory in children with and without specific language impairment , 2009, International journal of language & communication disorders.

[44]  Luis Jiménez,et al.  Dyslexic children show deficits in implicit sequence learning, but not in explicit sequence learning or contextual cueing , 2011, Annals of dyslexia.

[45]  Tim Curran,et al.  Attentional and Nonattentional Forms of Sequence Learning , 1993 .

[46]  Michael T. Ullman,et al.  Working, declarative and procedural memory in specific language impairment , 2012, Cortex.

[47]  A. Lang,et al.  Parkinson's disease. Second of two parts. , 1998, The New England journal of medicine.

[48]  Marjan Jahanshahi,et al.  Learning of ambiguous versus hybrid sequences by patients with Parkinson’s disease , 2004, Neuropsychologia.

[49]  J. Raven,et al.  Manual for Raven's progressive matrices and vocabulary scales , 1962 .

[50]  Axel Cleeremans,et al.  Can sequence learning be implicit? New evidence with the process dissociation procedure , 2001, Psychonomic bulletin & review.

[51]  L. Squire Memory systems of the brain: A brief history and current perspective , 2004, Neurobiology of Learning and Memory.

[52]  H. Eichenbaum,et al.  Towards a functional organization of episodic memory in the medial temporal lobe , 2012, Neuroscience & Biobehavioral Reviews.

[53]  Hsinjen Julie Hsu,et al.  Sequence-specific procedural learning deficits in children with specific language impairment , 2014, Developmental science.

[54]  Ferenc Kemény,et al.  Domain-general sequence learning deficit in specific language impairment. , 2014, Neuropsychology.

[55]  E. Soetens,et al.  Sequence learning and sequential effects , 2004, Psychological research.

[56]  M. Ullman,et al.  Specific Language Impairment is not Specific to Language: the Procedural Deficit Hypothesis , 2005, Cortex.

[57]  P. Maruff,et al.  Spatio-visual memory of children with specific language impairment: evidence for generalized processing problems. , 2005, International journal of language & communication disorders.

[58]  D Yves von Cramon,et al.  Rule learning in a serial reaction time task: an fMRI study on patients with early Parkinson's disease. , 2003, Brain research. Cognitive brain research.

[59]  Jonas Persson,et al.  Grammar predicts procedural learning and consolidation deficits in children with Specific Language Impairment. , 2011, Research in developmental disabilities.

[60]  G. Conti-Ramsden,et al.  Long-Term Memory: A Review and Meta-Analysis of Studies of Declarative and Procedural Memory in Specific Language Impairment , 2013, Topics in language disorders.

[61]  M. Nissen,et al.  Procedural learning is impaired in Huntington's disease: Evidence from the serial reaction time task , 1991, Neuropsychologia.

[62]  M. Van der Linden,et al.  Nondeclarative learning in children with Specific Language Impairment: Predicting regularities in the visuomotor, phonological, and cognitive domains , 2014, Child neuropsychology : a journal on normal and abnormal development in childhood and adolescence.

[63]  L. Squire,et al.  Structure and function of declarative and nondeclarative memory systems. , 1996, Proceedings of the National Academy of Sciences of the United States of America.

[64]  Sarah A. J. Reading,et al.  Functional MRI study of a serial reaction time task in Huntington's disease , 2004, Psychiatry Research: Neuroimaging.

[65]  Simon B. Eickhoff,et al.  A quantitative meta-analysis and review of motor learning in the human brain , 2013, NeuroImage.

[66]  J. Bruce Tomblin,et al.  Procedural Learning in Adolescents With and Without Specific Language Impairment , 2007 .

[67]  Richard N. Aslin,et al.  The neural correlates of statistical learning in a word segmentation task: An fMRI study , 2013, Brain and Language.

[68]  Mark Hallett,et al.  The role of the dorsolateral prefrontal cortex in implicit procedural learning , 2004, Experimental Brain Research.

[69]  D. C. Howell Statistical Methods for Psychology , 1987 .

[70]  E. Robertson The Serial Reaction Time Task: Implicit Motor Skill Learning? , 2007, The Journal of Neuroscience.