Asymmetrical involvement of frontal lobes in social reasoning.

The frontal lobes are widely implicated in logical reasoning. Recent neuroimaging studies suggest that frontal lobe involvement in reasoning is asymmetric (L>R) and increases with the presence of familiar, meaningful content in the reasoning situation. However, neuroimaging data can only provide sufficiency criteria. To determine the necessity of prefrontal involvement in logical reasoning, we tested 19 patients with focal frontal lobe lesions and 19 age- and education-matched normal controls on the Wason Card Selection Task, while manipulating social knowledge. Patients and controls performed equivalently on the arbitrary rule condition. Normal controls showed the expected improvement in the social knowledge conditions, but frontal lobe patients failed to show this facilitation in performance. Furthermore, left hemisphere patients were more affected than right hemisphere patients, suggesting that frontal lobe involvement in reasoning is asymmetric (L>R) and necessary for reasoning about social situations.

[1]  D. Laming,et al.  Misinterpretation of conditional statements in Wason's selection task , 2001, Psychological research.

[2]  Susan Robinson,et al.  Dissociation of mechanisms of reading in Alzheimer's disease , 1992, Brain and Language.

[3]  G. Gigerenzer,et al.  Domain-specific reasoning: Social contracts, cheating, and perspective change , 1992, Cognition.

[4]  Richard S. J. Frackowiak,et al.  Other minds in the brain: a functional imaging study of “theory of mind” in story comprehension , 1995, Cognition.

[5]  A. Damasio,et al.  I. Acquisition of social knowledge is related to the prefrontal cortex. , 2000, Journal of neurology.

[6]  A. Damasio,et al.  Neurobiology of Decision-Making , 2012, Research and Perspectives in Neurosciences.

[7]  Hanna Damasio,et al.  Impairment of social and moral behavior related to early damage in human prefrontal cortex , 1999, Nature Neuroscience.

[8]  Vinod Goel,et al.  Explaining modulation of reasoning by belief , 2003, Cognition.

[9]  E. Golding,et al.  The Effect of Unilateral Brain Lesion on Reasoning , 1981, Cortex.

[10]  Laure Zago,et al.  Access to Deductive Logic Depends on a Right Ventromedial Prefrontal Area Devoted to Emotion and Feeling: Evidence from a Training Paradigm , 2001, NeuroImage.

[11]  Richard A. Griggs,et al.  The effects of experience on performance in Wason’s selection task , 1982, Memory & cognition.

[12]  Richard A. Griggs,et al.  The elusive thematic‐materials effect in Wason's selection task , 1982 .

[13]  Vinod Goel,et al.  Neuroanatomical Correlates of Human Reasoning , 1998, Journal of Cognitive Neuroscience.

[14]  L M Parsons,et al.  New Evidence for Distinct Right and Left Brain Systems for Deductive versus Probabilistic Reasoning. , 2001, Cerebral cortex.

[15]  A. Damasio,et al.  Lesion analysis in neuropsychology , 1989 .

[16]  Laure Zago,et al.  Shifting from the Perceptual Brain to the Logical Brain: The Neural Impact of Cognitive Inhibition Training , 2000, Journal of Cognitive Neuroscience.

[17]  D. Read,et al.  Solving deductive-reasoning problems after unilateral temporal lobectomy , 1981, Brain and Language.

[18]  J. Grafman,et al.  The neurology of reasoning. , 2002, Archives of neurology.

[19]  L. Cosmides.  The logic of social exchange: Has natural selection shaped how humans reason? Studies with the Wason selection task , 1989, Cognition.

[20]  J. S. Evans,et al.  Matching bias in the selection task. , 1973 .

[21]  Tim Shallice,et al.  HIGHER-ORDER COGNITIVE IMPAIRMENTS AND FRONTAL-LOBE LESIONS IN MAN , 1991 .

[22]  R. Dolan,et al.  Functional neuroanatomy of three-term relational reasoning , 2001, Neuropsychologia.

[23]  Hanna Damasio,et al.  Neuropsychological Approaches to Reasoning and Decision-Making , 1996 .

[24]  M. Hallett,et al.  Modeling other minds , 1995, Neuroreport.

[25]  Dawn Langdon,et al.  The Role of the Left Hemisphere in Verbal and Spatial Reasoning Tasks , 2000, Cortex.

[26]  Ellen Perecman,et al.  Integrating Theory and Practice in Clinical Neuropsychology , 2018 .

[27]  J. Grafman,et al.  Are the frontal lobes implicated in “planning” functions? Interpreting data from the Tower of Hanoi , 1995, Neuropsychologia.

[28]  K. Holyoak,et al.  A System for Relational Reasoning in Human Prefrontal Cortex , 1999 .

[29]  Keith J Holyoak,et al.  Pragmatic reasoning schemas , 1985, Cognitive Psychology.

[30]  Donald T. Stuss,et al.  Executive functions and the frontal lobes: a conceptual view , 2000, Psychological research.

[31]  C. Frith,et al.  Development and neurophysiology of mentalizing. , 2003, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[32]  A. Benton,et al.  Frontal Lobe Function and Dysfunction , 1991 .

[33]  S. Kapur,et al.  The seats of reason? An imaging study of deductive and inductive reasoning , 1997, Neuroreport.

[34]  R. Dolan,et al.  Dissociation of Mechanisms Underlying Syllogistic Reasoning , 2000, NeuroImage.

[35]  Keith Stenning,et al.  Semantics as a Foundation for Psychology: A Case Study of Wason's Selection Task , 2001, J. Log. Lang. Inf..

[36]  D. Osherson,et al.  Distinct brain loci in deductive versus probabilistic reasoning , 1998, Neuropsychologia.

[37]  J. Grafman.  Plans, Actions, and Mental Sets: Managerial Knowledge Units in the Frontal Lobes , 2018, Integrating Theory and Practice in Clinical Neuropsychology.

[38]  B. Foss.  New Horizons in Psychology 1 , 1966 .

[39]  J. Fodor,et al.  Why we are so good at catching cheaters , 2000, Cognition.

[40]  Mark W Greenlee,et al.  Spatial imagery in deductive reasoning: a functional MRI study. , 2002, Brain research. Cognitive brain research.

[41]  D. Stuss,et al.  The Frontal Lobes , 1986 .

[42]  P. Wason,et al.  Natural and contrived experience in a reasoning problem , 1971 .