Towards a unified brain theory

An approach to collective aspects of the neocortical system is formulated by methods of modern non-equilibrium statistical mechanics. Microscopic neuronal synaptic interactions are first spatially averaged over columnar domains. These spatially ordered domains include well formulated fluctuations that retain contact with the original physical synaptic parameters. They also are a suitable substrate for macroscopic spatial—temporal regions described by Fokker-Planck and Lagrangian formalisms. This development clarifies similarities and differences among previous studies, suggests new analytically supported insights into neocortical function and permits future approximation or elaboration within current paradigms of collective systems.

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