Micromanipulation With Microrobots

Microrobots are promising tools for applications that require micromanipulation, such as single-cell manipulation and surgery, tissue engineering, and desktop manufacturing. This paper briefly reviews common microrobot actuation mechanisms, then reviews current progress in several capabilities that are desirable for micromanipulation, with an emphasis on optothermal microrobots.

[1]  Doyoung Byun,et al.  Use of an AC electric field in galvanotactic on/off switching of the motion of a microstructure blotted by Serratia marcescens , 2011 .

[2]  Lianqing Liu,et al.  A Micromanipulator and Transporter Based on Vibrating Bubbles in an Open Chip Environment , 2017, Micromachines.

[3]  Wenqi Hu,et al.  Micro-assembly using optically controlled bubble microrobots in saline solution , 2012, 2012 IEEE International Conference on Robotics and Automation.

[4]  Sylvain Martel,et al.  Computer 3D controlled bacterial transports and aggregations of microbial adhered nano-components , 2013, Journal of Micro-Bio Robotics.

[5]  M. Sitti,et al.  Multiple magnetic microrobot control using electrostatic anchoring , 2009 .

[6]  Jie Yang,et al.  Development of an Enhanced Electromagnetic Actuation System With Enlarged Workspace , 2017, IEEE/ASME Transactions on Mechatronics.

[7]  Mamoru Mitsuishi,et al.  Selective control method for multiple magnetic helical microrobots , 2011 .

[8]  Daniela Rus,et al.  Teleoperated Micromanipulation System Manufactured by Cut-and-Fold Techniques , 2017, IEEE Transactions on Robotics.

[9]  Guy M. Narbonne.  Push it , pull it , 2011 .

[10]  Dan O. Popa,et al.  Cooperative control of multiple untethered magnetic microrobots using a single magnetic field source , 2015, 2015 IEEE International Conference on Automation Science and Engineering (CASE).

[11]  Ben Wang,et al.  Light-Driven Hovering of a Magnetic Microswarm in Fluid. , 2020, ACS nano.

[12]  Vijay Kumar,et al.  A two dimensional vision-based force sensor for microrobotic applications , 2011 .

[13]  Antoine Barbot,et al.  On-chip Microfluidic Multimodal Swimmer toward 3D Navigation , 2016, Scientific Reports.

[14]  Bruce Randall Donald,et al.  Simultaneous Control of Multiple MEMS Microrobots , 2008, WAFR.

[15]  Wenqi Hu,et al.  Efficient single-cell poration by microsecond laser pulses. , 2015, Lab on a chip.

[16]  T. Huang,et al.  Selectively manipulable acoustic-powered microswimmers , 2015, Scientific Reports.

[17]  A STUDY ON ELECTROMAGNETIC FIELD AND FORCE FOR MAGNETIC MICRO-ROBOTS APPLICATIONS , 2020, Progress In Electromagnetics Research M.

[18]  Stefano Scheggi,et al.  Design of an Electromagnetic Setup for Independent Three-Dimensional Control of Pairs of Identical and Nonidentical Microrobots , 2019, IEEE Transactions on Robotics.

[19]  Antoine Ferreira,et al.  Two-Dimensional Robust Magnetic Resonance Navigation of a Ferromagnetic Microrobot Using Pareto Optimality , 2017, IEEE Transactions on Robotics.

[20]  Lidong Yang,et al.  Pattern generation and motion control of a vortex-like paramagnetic nanoparticle swarm , 2018, Int. J. Robotics Res..

[21]  Deasung Jang,et al.  Acoustic bubble-powered miniature rotor for wireless energy harvesting in a liquid medium , 2018, Sensors and Actuators A: Physical.

[22]  Metin Sitti,et al.  Three-dimensional heterogeneous assembly of coded microgels using an untethered mobile microgripper. , 2015, Lab on a chip.

[23]  Wenqi Hu,et al.  Cooperative micromanipulation using optically controlled bubble microrobots , 2012, 2012 IEEE International Conference on Robotics and Automation.

[24]  F. Novotný,et al.  Chemically programmable microrobots weaving a web from hormones , 2020, Nature Machine Intelligence.

[25]  T. Huang,et al.  Acoustic actuation of bioinspired microswimmers. , 2017, Lab on a chip.

[26]  M. Sitti,et al.  Biohybrid Microtube Swimmers Driven by Single Captured Bacteria. , 2017, Small.

[27]  Jiang Zhuang,et al.  Propulsion and Chemotaxis in Bacteria‐Driven Microswimmers , 2017, Advanced science.

[28]  Metin Sitti,et al.  Controlling two-dimensional collective formation and cooperative behavior of magnetic microrobot swarms , 2020, Int. J. Robotics Res..

[29]  Eric Diller,et al.  Programmable assembly of heterogeneous microparts by an untethered mobile capillary microgripper. , 2016, Lab on a chip.

[30]  Benjamin V. Johnson,et al.  Local Magnetic Field Design and Characterization for Independent Closed-Loop Control of Multiple Mobile Microrobots , 2020, IEEE/ASME Transactions on Mechatronics.

[31]  Eric D. Diller,et al.  Eight-Degrees-of-Freedom Remote Actuation of Small Magnetic Mechanisms , 2018, 2018 IEEE International Conference on Robotics and Automation (ICRA).

[32]  Changyou Chen,et al.  Construction of a microrobot system using magnetotactic bacteria for the separation of Staphylococcus aureus , 2014, Biomedical Microdevices.

[33]  Wei Gao,et al.  A microrobotic system guided by photoacoustic computed tomography for targeted navigation in intestines in vivo , 2019, Science Robotics.

[34]  Aude Bolopion,et al.  Closed-Loop Control of a Magnetic Particle at the Air–Liquid Interface , 2017, IEEE Transactions on Automation Science and Engineering.

[35]  J. Glückstad,et al.  Gearing up for optical microrobotics: micromanipulation and actuation of synthetic microstructures by optical forces , 2013 .

[36]  Bradley J. Nelson,et al.  Magnetic actuation of a cylindrical microrobot using time-delay-estimation closed-loop control: modeling and experiments , 2014 .

[37]  Metin Sitti,et al.  Mobile microrobots for bioengineering applications. , 2017, Lab on a chip.

[38]  Jong-Oh Park,et al.  Multifunctional Biodegradable Microrobot with Programmable Morphology for Biomedical Applications. , 2020, ACS nano.

[39]  M. Sitti,et al.  Magnetic Resonance Imaging System–Driven Medical Robotics , 2020, Adv. Intell. Syst..

[40]  Jong-Oh Park,et al.  Magnetic actuated pH-responsive hydrogel-based soft micro-robot for targeted drug delivery , 2016 .

[41]  Qi Zhou,et al.  Multifunctional biohybrid magnetite microrobots for imaging-guided therapy , 2017, Science Robotics.

[42]  G. Whitesides,et al.  Microoxen: microorganisms to move microscale loads. , 2005, Proceedings of the National Academy of Sciences of the United States of America.

[43]  Wenqi Hu,et al.  Micro-assembly using optically controlled bubble microrobots , 2011 .

[44]  Pascal Hersen,et al.  Biophysics: Push it, pull it , 2011, Nature.

[45]  Joseph Wang,et al.  Swimming Microrobot Optical Nanoscopy. , 2016, Nano letters.

[46]  F. Qiu,et al.  Controlled In Vivo Swimming of a Swarm of Bacteria‐Like Microrobotic Flagella , 2015, Advanced materials.

[47]  Eric Diller,et al.  Biomedical Applications of Untethered Mobile Milli/Microrobots , 2015, Proceedings of the IEEE.

[48]  Qihui Fan,et al.  Localized Single-Cell Lysis and Manipulation Using Optothermally-Induced Bubbles , 2017, Micromachines.

[49]  D. Wiersma,et al.  Structured light enables biomimetic swimming and versatile locomotion of photoresponsive soft microrobots. , 2016, Nature materials.

[50]  M. J. Kim,et al.  Artificial magnetotactic motion control of Tetrahymena pyriformis using ferromagnetic nanoparticles: A tool for fabrication of microbiorobots , 2010 .

[51]  Taylor A. Howell,et al.  Sorting Rotating Micromachines by Variations in Their Magnetic Properties , 2018 .

[52]  Vijay Kumar,et al.  Control of multiple microrobots with multiscale magnetic field superposition , 2017, 2017 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS).

[53]  Metin Sitti,et al.  Control methodologies for a heterogeneous group of untethered magnetic micro-robots , 2011, Int. J. Robotics Res..

[54]  Aaron T. Ohta,et al.  Parallel actuation of multiple bubble microrobots in saline solution in an open reservoir , 2017, 2017 IEEE 12th International Conference on Nano/Micro Engineered and Molecular Systems (NEMS).

[55]  Metin Sitti,et al.  Simultaneous Six-Degree-of-Freedom Control of a Single-Body Magnetic Microrobot , 2019, IEEE Robotics and Automation Letters.

[56]  Franziska Ullrich,et al.  Mobility experiments with microrobots for minimally invasive intraocular surgery. , 2013, Investigative ophthalmology & visual science.

[57]  Metin Sitti,et al.  Independent Actuation of Two-Tailed Microrobots , 2018, IEEE Robotics and Automation Letters.

[58]  Jian Feng,et al.  Micropropulsion by an acoustic bubble for navigating microfluidic spaces. , 2015, Lab on a chip.

[59]  M. Sitti,et al.  Untethered micro-robotic coding of three-dimensional material composition , 2014, Nature Communications.

[60]  B. Nelson,et al.  Surface-Chemistry-Mediated Control of Individual Magnetic Helical Microswimmers in a Swarm. , 2018, ACS nano.

[61]  M. Sitti,et al.  Cohesive self-organization of mobile microrobotic swarms. , 2019, Soft matter.

[62]  Fumihito Arai,et al.  High-Speed Magnetic Microrobot Actuation in a Microfluidic Chip by a Fine V-Groove Surface , 2013, IEEE Transactions on Robotics.

[63]  Jennifer Sturgis,et al.  Bacteria-mediated delivery of nanoparticles and cargo into cells. , 2007, Nature nanotechnology.

[64]  François Gallaire,et al.  Laser-induced force on a microfluidic drop: origin and magnitude. , 2009, Langmuir : the ACS journal of surfaces and colloids.

[65]  Xiasheng Guo,et al.  A Human Microrobot Interface Based on Acoustic Manipulation. , 2019, ACS nano.

[66]  Qiang He,et al.  Reconfigurable magnetic microrobot swarm: Multimode transformation, locomotion, and manipulation , 2019, Science Robotics.

[67]  Metin Sitti,et al.  High‐Yield Production of Biohybrid Microalgae for On‐Demand Cargo Delivery , 2020, Advanced science.

[68]  Wenqi Hu,et al.  Hydrogel microrobots actuated by optically generated vapour bubbles. , 2012, Lab on a chip.

[69]  Fumihito Arai,et al.  Microrobot with passive diamagnetic levitation for microparticle manipulations , 2017 .

[70]  David J. Cappelleri,et al.  Towards Mobile Microrobot Swarms for Additive Micromanufacturing , 2014 .

[71]  Sylvain Martel,et al.  Enabling automated magnetic resonance imaging-based targeting assessment during dipole field navigation , 2016 .

[72]  M. Sitti,et al.  Translational prospects of untethered medical microrobots , 2019, Progress in Biomedical Engineering.

[73]  Metin Sitti,et al.  Bioadhesive Bacterial Microswimmers for Targeted Drug Delivery in the Urinary and Gastrointestinal Tracts , 2017, Advanced science.

[74]  Aaron T. Ohta,et al.  Optical Manipulation of Cells , 2017 .

[75]  Stephane Regnier,et al.  Laser-Induced Thermocapillary Convection for Mesoscale Manipulation , 2009 .

[76]  Oliver G Schmidt,et al.  Cellular Cargo Delivery: Toward Assisted Fertilization by Sperm-Carrying Micromotors. , 2016, Nano letters.

[77]  Noboru Takahashi,et al.  Vision-assisted micromanipulation using closed-loop actuation of multiple microrobots , 2017, Robotics and biomimetics.

[78]  Fumihito Arai,et al.  On-Chip Enucleation of Bovine Oocytes using Microrobot-Assisted Flow-Speed Control , 2013, Micromachines.

[79]  David J. Cappelleri,et al.  A Magnetic Microrobot with in situ Force Sensing Capabilities , 2014, Robotics.

[80]  Wei Wang,et al.  Steering acoustically propelled nanowire motors toward cells in a biologically compatible environment using magnetic fields. , 2013, Langmuir : the ACS journal of surfaces and colloids.

[81]  George J. Pappas,et al.  Electrokinetic and optical control of bacterial microrobots , 2011 .

[82]  Metin Sitti,et al.  Independent control of multiple magnetic microrobots in three dimensions , 2013, Int. J. Robotics Res..

[83]  David H Gracias,et al.  Tetherless thermobiochemically actuated microgrippers , 2009, Proceedings of the National Academy of Sciences.

[84]  Yuebing Zheng,et al.  Optothermal Manipulations of Colloidal Particles and Living Cells. , 2018, Accounts of chemical research.

[85]  Jianbin Qiu,et al.  Autonomous Collision-Free Navigation of Microvehicles in Complex and Dynamically Changing Environments. , 2017, ACS nano.

[86]  T. Ikeda,et al.  Photomechanics: Directed bending of a polymer film by light , 2003, Nature.

[87]  M. Sitti,et al.  Light-Triggered Drug Release from 3D-Printed Magnetic Chitosan Microswimmers. , 2018, ACS nano.

[88]  Metin Sitti,et al.  Microrobotics and Microorganisms: Biohybrid Autonomous Cellular Robots , 2019, Annu. Rev. Control. Robotics Auton. Syst..

[89]  Wei Wang,et al.  Autonomous motion of metallic microrods propelled by ultrasound. , 2012, ACS nano.

[90]  Metin Sitti,et al.  Bio-hybrid cell-based actuators for microsystems. , 2014, Small.

[91]  Zhidong Wang,et al.  Cooperative Micromanipulation Using the Independent Actuation of Fifty Microrobots in Parallel , 2017, Scientific Reports.

[92]  Amar S. Basu,et al.  Shaping high-speed Marangoni flow in liquid films by microscale perturbations in surface temperature , 2007 .

[93]  Jan Lammerding,et al.  Mechanotransduction gone awry , 2009, Nature Reviews Molecular Cell Biology.

[94]  F. Zhao,et al.  Photothermal Generation of Programmable Microbubble Array on Nanoporous Gold Disks , 2018, 2018 International Conference on Optical MEMS and Nanophotonics (OMN).

[95]  B.R. Donald,et al.  Planar Microassembly by Parallel Actuation of MEMS Microrobots , 2008, Journal of Microelectromechanical Systems.

[96]  Zhidong Wang,et al.  Collaborative micromanipulation using multiple bubble microrobots in an open reservoir , 2017 .

[97]  D. Contreras,et al.  Dynamics of electrostatic inchworm motors for silicon microrobots , 2017, 2017 International Conference on Manipulation, Automation and Robotics at Small Scales (MARSS).

[98]  Metin Sitti,et al.  Programmable Collective Behavior in Dynamically Self‐Assembled Mobile Microrobotic Swarms , 2018, Advanced science.

[99]  L. Mair,et al.  Highly Acid‐Resistant, Magnetically Steerable Acoustic Micromotors Prepared by Coating Gold Microrods with Fe3O4 Nanoparticles via pH Adjustment , 2017 .

[100]  Fumihito Arai,et al.  Manipulating Microrobots Using Balanced Magnetic and Buoyancy Forces , 2018, Micromachines.

[101]  Eric Diller,et al.  Three-dimensional independent control of multiple magnetic microrobots via inter-agent forces , 2020, Int. J. Robotics Res..

[102]  Benjamin V. Johnson,et al.  A Microforce-Sensing Mobile Microrobot for Automated Micromanipulation Tasks , 2019, IEEE Transactions on Automation Science and Engineering.

[103]  Metin Sitti,et al.  Acoustically powered surface-slipping mobile microrobots , 2020, Proceedings of the National Academy of Sciences.

[104]  Dongdong Jin,et al.  Active generation and magnetic actuation of microrobotic swarms in bio-fluids , 2019, Nature Communications.

[105]  Lianqing Liu,et al.  2D to 3D Manipulation and Assembly of Microstructures Using Optothermally Generated Surface Bubble Microrobots. , 2019, Small.