Topographic relationship between the receptive fields of neurons in the motor cortex and the movements elicited by focal stimulation in freely moving cats.

Single unit recording and microstimulation were performed in the primary motor area of unanesthetized, unrestrained cats.1. Neurons in the motor cortex were excited by physiological stimulation on the skin and deep tissues.Modality and receptive fields for 96 units were studied in detail.2. When focal stimuli were applied through the microelectrode to the same region where the unit spike was recorded, localized movements elicited were found to be closely related to the receptive fields of the units recorded in the stimulus site.3. Thresholds of movements were measured at different depths along the electrode penetrations.Each focal region concerned with a specific movement was found to have considerable extent (usually more than 0.5mm).4. The relationship between sensory receptive fields of units and movements elicited by focal stimulation were studied in 59 focal regions.A close topographic correlation were found between the two.There was a tendency for the limb movement to avoid the contacting ob ject.5. Penetrations in the primary motor and primary sensory areas were performed in a same animal.No movement was elicited with microstimulation of less than 100μ A in the sensory area.

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