European guidelines on cardiovascular disease prevention in clinical practice. Third Joint Task Force Of European and other societies on cardiovascular disease prevention in clinical practice (constituted by representatives of eight societies and by invited experts).

Preamble Guidelines aim to present all the relevant evidence on a particular issue in order to help physicians to weigh the benefits and risks of a particular diagnostic or therapeutic procedure. They should be helpful in everyday clinical decision-making. A great number of guidelines have been issued in recent years by different organisations–European Society of Cardiology (ESC), American Heart Association (AHA), American College of Cardiology (ACC), and other related societies. By means of links to web sites of National Societies several hundred guidelines are available. This profusion can put at stake the authority and validity of guidelines, which can only be guaranteed if they have been developed by an unquestionable decision-making process. This is one of the reasons why the ESC and others have issued recommendations for formulating and issuing guidelines. In spite of the fact that standards for issuing good quality guidelines are well defined, recent surveys of guidelines published in peer-reviewed journals between 1985 and 1998 have shown that methodological standards were not complied with in the vast majority of cases. It is therefore of great importance that guidelines and recommendations are presented in formats that are easily interpreted. Subsequently, their implementation programmes must also be well conducted. Attempts have been made to determine whether guidelines improve the quality of clinical practice and the utilisation of health resources. In addition, the legal implications of medical guidelines have been discussed and examined, resulting in position documents, which have been published by a specific task force. The ESC Committee for practice guidelines (CPG) supervises and coordinates the preparation of new guidelines and expert consensus documents produced by task forces, expert groups or consensus panels. The Committee is also responsible for the endorsement of these guidelines or statements.

[1]  S. Priori,et al.  2003 European Society of Hypertension-European Society of Cardiology Guidelines for the Management of Arterial Hypertension , 2004, Heart Drug.

[2]  C. White,et al.  Determination of coronary calcium with Multi-slice Spiral Computed Tomography: a comparative study with Electron-beam CT , 2002, The International Journal of Cardiovascular Imaging.

[3]  G. Mancia,et al.  Combination Treatment in Antihypertensive Drug Trials , 1997, Cardiovascular Drugs and Therapy.

[4]  J. Slattery,et al.  Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). 1994. , 1994, Atherosclerosis. Supplements.

[5]  L. Niskanen,et al.  Microalbuminuria predicts the development of serum lipoprotein abnormalities favouring atherogenesis in newly diagnosed type 2 (non-insulin-dependent) diabetic patients , 1990, Diabetologia.

[6]  Timothy W. Smith,et al.  Blood-pressure responses during social interaction in high- and low-cynically hostile males , 1989, Journal of Behavioral Medicine.

[7]  T. Deckert,et al.  Abnormalities in plasmas concentrations of lipoproteins and fibrinogen in Type 1 (insulin-dependent) diabetic patients with increased urinary albumin excretion , 1988, Diabetologia.

[8]  F. Turnbull Effects of different blood-pressure-lowering regimens on major cardiovascular events: results of prospectively-designed overviews of randomised trials , 2003, The Lancet.

[9]  K. Fox,et al.  Efficacy of perindopril in reduction of cardiovascular events among patients with stable coronary artery disease: randomised, double-blind, placebo-controlled, multicentre trial (the EUROPA study) , 2003, The Lancet.

[10]  H. Tunstall-Pedoe,et al.  Estimation of ten-year risk of fatal cardiovascular disease in Europe: the SCORE project. , 2003, European heart journal.

[11]  Kiang Liu,et al.  Electron-Beam Tomography Coronary Artery Calcium and Cardiac Events: A 37-Month Follow-Up of 5635 Initially Asymptomatic Low- to Intermediate-Risk Adults , 2003, Circulation.

[12]  Yutaka Imai,et al.  European Society of Hypertension recommendations for conventional, ambulatory and home blood pressure measurement , 2003, Journal of hypertension.

[13]  D. Berwick Disseminating innovations in health care. , 2003, JAMA.

[14]  R. Collins,et al.  Prevention of coronary and stroke events with atorvastatin in hypertensive patients who have average or lower-than-average cholesterol concentrations, in the Anglo-Scandinavian Cardiac Outcomes Trial—Lipid Lowering Arm (ASCOT-LLA): a multicentre randomised controlled trial , 2003, The Lancet.

[15]  N. Cook,et al.  Comparison of C-reactive protein and low-density lipoprotein cholesterol levels in the prediction of first cardiovascular events , 2003 .

[16]  C. Reid,et al.  A comparison of outcomes with angiotensin-converting--enzyme inhibitors and diuretics for hypertension in the elderly. , 2003, The New England journal of medicine.

[17]  V. Gudnason,et al.  Systematic Family Screening for Familial Hypercholesterolemia in Iceland , 2003, Arteriosclerosis, thrombosis, and vascular biology.

[18]  Oluf Pedersen,et al.  Multifactorial intervention and cardiovascular disease in patients with type 2 diabetes. , 2003, The New England journal of medicine.

[19]  E. Lander,et al.  Meta-analysis of genetic association studies supports a contribution of common variants to susceptibility to common disease , 2003, Nature Genetics.

[20]  Cardio-vascular disease in Europe: challenges for the medical profession. Opening address of the 2002 Congress European Society of Cardiology. , 2003, European heart journal.

[21]  A. Evans,et al.  Plasma fibrinogen explains much of the difference in risk of coronary heart disease between France and Northern Ireland. The PRIME study. , 2003, Atherosclerosis.

[22]  Lincoln Stein,et al.  The SNP Consortium website: past, present and future , 2003, Nucleic Acids Res..

[23]  F. Crea,et al.  Widespread coronary inflammation in unstable angina. , 2003, The New England journal of medicine.

[24]  Barry R. Davis,et al.  Major outcomes in moderately hypercholesterolemic, hypertensive patients randomized to pravastatin vs usual care: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT-LLT). , 2002, JAMA.

[25]  B. Davis,et al.  Major outcomes in high-risk hypertensive patients randomized to angiotensin-converting enzyme inhibitor or calcium channel blocker vs diuretic: The Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial (ALLHAT). , 2002, JAMA.

[26]  James W. Anderson,et al.  Diabetes, plasma insulin, and cardiovascular disease: subgroup analysis from the Department of Veterans Affairs high-density lipoprotein intervention trial (VA-HIT). , 2002, Archives of internal medicine.

[27]  Jukka T Salonen,et al.  The metabolic syndrome and total and cardiovascular disease mortality in middle-aged men. , 2002, JAMA.

[28]  L. Niskanen,et al.  Metabolic syndrome and development of diabetes mellitus: application and validation of recently suggested definitions of the metabolic syndrome in a prospective cohort study. , 2002, American journal of epidemiology.

[29]  N. Freemantle,et al.  Management of heart failure in primary care (the IMPROVEMENT of Heart Failure Programme): an international survey , 2002, The Lancet.

[30]  P. Macfarlane,et al.  Pravastatin in elderly individuals at risk of vascular disease (PROSPER): a randomised controlled trial , 2002, The Lancet.

[31]  L. Mosca C-reactive protein--to screen or not to screen? , 2002, The New England journal of medicine.

[32]  D. Pella,et al.  Effect of an Indo-Mediterranean diet on progression of coronary artery disease in high risk patients (Indo-Mediterranean Diet Heart Study): a randomised single-blind trial , 2002, The Lancet.

[33]  M. Bond,et al.  Impact of multiple coronary risk factors on the intima-media thickness of different segments of carotid artery in healthy young adults (The Bogalusa Heart Study). , 2002, The American journal of cardiology.

[34]  J. Danesh,et al.  von Willebrand factor and coronary heart disease: prospective study and meta-analysis. , 2002, European heart journal.

[35]  Petra Verhoef,et al.  MTHFR 677C-->T polymorphism and risk of coronary heart disease: a meta-analysis. , 2002, JAMA.

[36]  Per Magne Ueland,et al.  Homocysteine and risk of ischemic heart disease and stroke: a meta-analysis. , 2002, JAMA.

[37]  Robert Detrano,et al.  Combined Use of Computed Tomography Coronary Calcium Scores and C-Reactive Protein Levels in Predicting Cardiovascular Events in Nondiabetic Individuals , 2002, Circulation.

[38]  I. Graham,et al.  Smoking and plasma homocysteine , 2002, European Heart Journal.

[39]  A. Hofman,et al.  Coronary calcification detected by electron-beam computed tomography and myocardial infarction. The Rotterdam Coronary Calcification Study. , 2002, European heart journal.

[40]  S. Yusuf,et al.  Benefit of Clopidogrel in Patients With Acute Coronary Syndromes Without ST-Segment Elevation in Various Risk Groups , 2002, Circulation.

[41]  S. Ebrahim,et al.  Systematic review of long term effects of advice to reduce dietary salt in adults , 2002, BMJ : British Medical Journal.

[42]  D. Levy,et al.  C-Reactive Protein Is Associated With Subclinical Epicardial Coronary Calcification in Men and Women: The Framingham Heart Study , 2002, Circulation.

[43]  A. Reunanen,et al.  Flavonoid intake and risk of chronic diseases. , 2002, The American journal of clinical nutrition.

[44]  S. Taddei,et al.  Endothelial dysfunction in essential hypertension: clinical implications. , 2002, Journal of hypertension.

[45]  S. Achenbach,et al.  Influence of Lipid-Lowering Therapy on the Progression of Coronary Artery Calcification: A Prospective Evaluation , 2002, Circulation.

[46]  J. López-Miranda,et al.  Protective effect of dietary monounsaturated fat on arteriosclerosis: beyond cholesterol. , 2002, Atherosclerosis.

[47]  D. Vlahov,et al.  Effect of cocaine use on coronary calcium among black adults in Baltimore, Maryland. , 2002, The American journal of cardiology.

[48]  G. Mancia,et al.  Systolic and diastolic blood pressure control in antihypertensive drug trials. , 2002, Journal of hypertension.

[49]  René M. Botnar,et al.  Three-Dimensional Black-Blood Cardiac Magnetic Resonance Coronary Vessel Wall Imaging Detects Positive Arterial Remodeling in Patients With Nonsignificant Coronary Artery Disease , 2002, Circulation.

[50]  E. Boerwinkle,et al.  Heritability of Coronary Artery Calcium Quantity Measured by Electron Beam Computed Tomography in Asymptomatic Adults , 2002, Circulation.

[51]  A. Schmermund,et al.  Age and gender distribution of coronary artery calcium measured by four-slice computed tomography in 2,030 persons with no symptoms of coronary artery disease. , 2002, The American journal of cardiology.

[52]  AndrewJ. S. Coats MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20 536 high-risk individuals: a randomised placebocontrolled trial , 2002, The Lancet.

[53]  P. V. van Ooijen,et al.  Comparison of coronary imaging between magnetic resonance imaging and electron beam computed tomography. , 2002, The American journal of cardiology.

[54]  G. Mancia,et al.  Role of echocardiography and carotid ultrasonography in stratifying risk in patients with essential hypertension: the Assessment of Prognostic Risk Observational Survey , 2002, Journal of hypertension.

[55]  B. Nordestgaard,et al.  Transvascular Low-Density Lipoprotein Transport in Patients With Diabetes Mellitus (Type 2): A Noninvasive In Vivo Isotope Technique , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[56]  P. Serruys,et al.  Fluvastatin for prevention of cardiac events following successful first percutaneous coronary intervention: a randomized controlled trial. , 2002, JAMA.

[57]  J. Guralnik,et al.  The Ankle Brachial Index Is Associated with Leg Function and Physical Activity: The Walking and Leg Circulation Study , 2002, Annals of Internal Medicine.

[58]  M. Laakso,et al.  Acarbose for prevention of type 2 diabetes mellitus: the STOP-NIDDM randomised trial , 2002, The Lancet.

[59]  S. Ziebland,et al.  Effects of fruit and vegetable consumption on plasma antioxidant concentrations and blood pressure: a randomised controlled trial , 2002, The Lancet.

[60]  A. Hofman,et al.  The association between coronary calcification assessed by electron beam computed tomography and measures of extracoronary atherosclerosis: the Rotterdam Coronary Calcification Study. , 2002, Journal of the American College of Cardiology.

[61]  Margaret Thorogood,et al.  Cost effectiveness analysis of different approaches of screening for familial hypercholesterolaemia , 2002, BMJ : British Medical Journal.

[62]  M. Budoff,et al.  Coronary calcium scanning adds incremental value to patients with positive stress tests. , 2002, American heart journal.

[63]  L. Tavazzi,et al.  Early Protection Against Sudden Death by n-3 Polyunsaturated Fatty Acids After Myocardial Infarction Time-Course Analysis of the Results of the Gruppo Italiano per lo Studio della Sopravvivenza nell’Infarto Miocardico (GISSI)-Prevenzione , 2002 .

[64]  Jixian Wang,et al.  Comparison of cardiovascular risk between patients with type 2 diabetes and those who had had a myocardial infarction: cross sectional and cohort studies , 2002, BMJ : British Medical Journal.

[65]  D. Berman,et al.  Continuous Probabilistic Prediction of Angiographically Significant Coronary Artery Disease Using Electron Beam Tomography , 2002, Circulation.

[66]  J. Manson,et al.  Blood levels of long-chain n-3 fatty acids and the risk of sudden death. , 2002, The New England journal of medicine.

[67]  J. Manson,et al.  Fish and omega-3 fatty acid intake and risk of coronary heart disease in women. , 2002, JAMA.

[68]  Alex P. Reiner,et al.  Diuretic Therapy, the α-Adducin Gene Variant, and the Risk of Myocardial Infarction or Stroke in Persons With Treated Hypertension , 2002 .

[69]  Y. Ben-Shlomo,et al.  A life course approach to chronic disease epidemiology: conceptual models, empirical challenges and interdisciplinary perspectives , 2002 .

[70]  N. Martin,et al.  Heritabilities of apolipoprotein and lipid levels in three countries. , 2002, Twin research : the official journal of the International Society for Twin Studies.

[71]  Steven Snapinn,et al.  Cardiovascular morbidity and mortality in patients with diabetes in the Losartan Intervention For Endpoint reduction in hypertension study (LIFE): a randomised trial against atenolol , 2002, The Lancet.

[72]  M. Nieminen,et al.  For Personal Use. Only Reproduce with Permission from the Lancet Publishing Group , 2022 .

[73]  N. Weissman,et al.  Volumetric intravascular ultrasound quantification of the amount of atherosclerosis and calcium in nonstenotic arterial segments. , 2002, The American journal of cardiology.

[74]  Victor F. Froelicher,et al.  Exercise capacity and mortality among men referred for exercise testing. , 2002, The New England journal of medicine.

[75]  Robert Parrish,et al.  Improving quality of care for acute myocardial infarction: The Guidelines Applied in Practice (GAP) Initiative. , 2002, JAMA.

[76]  M. Rich From clinical trials to clinical practice: bridging the GAP. , 2002, JAMA.

[77]  A. Keech,et al.  Relationship Between Lipid Levels and Clinical Outcomes in the Long-Term Intervention With Pravastatin in Ischemic Disease (LIPID) Trial: To What Extent Is the Reduction in Coronary Events With Pravastatin Explained by On-Study Lipid Levels? , 2002, Circulation.

[78]  Jonathan C. Cohen,et al.  Autosomal recessive hypercholesterolaemia in Sardinia, Italy, and mutations in ARH: a clinical and molecular genetic analysis , 2002, The Lancet.

[79]  A. Connor,et al.  The way I see it: House officers need formal career development , 2002 .

[80]  S. Silber Comparison of spiral and electron beam tomography in the evaluation of coronary calcification in asymptomatic persons. , 2002, International journal of cardiology.

[81]  M. Budoff,et al.  Coronary calcium and cardiovascular event risk: evaluation by age- and sex-specific quartiles. , 2002, American heart journal.

[82]  C. Cannon,et al.  Assessment of compliance with the American College of Cardiology/American Heart Association guidelines for patients with acute coronary syndromes admitted to a tertiary care hospital coronary care unit. , 2002, Critical pathways in cardiology.

[83]  J. Frohlich,et al.  Hypertriglyceridemic hyperapoB in type 2 diabetes. , 2002, Diabetes care.

[84]  C. Schindler,et al.  N-3 polyunsaturated fatty acids in coronary heart disease: a meta-analysis of randomized controlled trials. , 2002, The American journal of medicine.

[85]  Zahi A Fayad,et al.  Progression and Regression of Atherosclerotic Lesions: Monitoring With Serial Noninvasive Magnetic Resonance Imaging , 2002, Circulation.

[86]  T. Spector,et al.  Activation markers of coagulation and fibrinolysis in twins: heritability of the prethrombotic state , 2002, The Lancet.

[87]  T. Raghunathan,et al.  Cell Membrane Trans-Fatty Acids and the Risk of Primary Cardiac Arrest , 2002, Circulation.

[88]  S. Fowler,et al.  Reduction in the incidence of type 2 diabetes with lifestyle intervention or metformin. , 2002 .

[89]  Uusitalo Ulla,et al.  Part III. Can we turn back the clock or modify the adverse dynamics? Programme and policy issues , 2002, Public Health Nutrition.

[90]  James P. Wilson,et al.  FDA Adverse Event Reports on Statin-Associated Rhabdomyolysis , 2002, The Annals of pharmacotherapy.

[91]  R Clarke,et al.  Underestimation of the importance of blood pressure and cholesterol for coronary heart disease mortality in old age. , 2002, European heart journal.

[92]  P. Mueller,et al.  Homocyst(e)ine and cardiovascular disease: a systematic review of the evidence with special emphasis on case-control studies and nested case-control studies. , 2002, International journal of epidemiology.

[93]  R. Clarke Commentary: an updated review of the published studies of homocysteine and cardiovascular disease. , 2002, International journal of epidemiology.

[94]  V. Salomaa,et al.  Hemostatic Factors as Predictors of Coronary Events and Total Mortality: The FINRISK ’92 Hemostasis Study , 2002, Arteriosclerosis, thrombosis, and vascular biology.

[95]  Renu Virmani,et al.  Morphological Predictors of Arterial Remodeling in Coronary Atherosclerosis , 2002, Circulation.

[96]  A. Mattioli,et al.  Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients , 2002, BMJ : British Medical Journal.

[97]  Paolo Raggi,et al.  High coronary artery calcium scores pose an extremely elevated risk for hard events. , 2002, Journal of the American College of Cardiology.

[98]  C. Mulrow,et al.  Aspirin for the Primary Prevention of Cardiovascular Events: A Summary of the Evidence for the U.S. Preventive Services Task Force , 2002, Annals of Internal Medicine.

[99]  U. P. S. T. Force,et al.  Measuring Quality: Are We Ready To Compare the Quality of Care among Physician Groups? , 2002, Annals of Internal Medicine.

[100]  Catherine Sudlow,et al.  Collaborative meta-analysis of randomised trials of antiplatelet therapy for prevention of death, myocardial infarction, and stroke in high risk patients , 2002, BMJ : British Medical Journal.

[101]  A. Coats MRC/BHF Heart Protection Study of antioxidant vitamin supplementation in 20 536 high-risk individuals: a randomised placebo-controlled trial , 2002 .

[102]  S. Yusuf MRC/BHF Heart Protection Study of cholesterol lowering with simvastatin in 20536 high-risk individuals: a randomised placebo-controlled trial. Commentary , 2002 .

[103]  G. Burell,et al.  Women’s hearts need special treatment , 2002, International journal of behavioral medicine.

[104]  M. Marmot,et al.  The role of psychobiological pathways in socio-economic inequalities in cardiovascular disease risk. , 2002, European heart journal.

[105]  S. Humphries,et al.  The Effect of Fibrinogen Genotype on Fibrinogen Levels after Strenuous Physical Exercise , 2002, Thrombosis and Haemostasis.

[106]  Lisa J. Martin,et al.  A comprehensive linkage analysis for myocardial infarction and its related risk factors , 2002, Nature Genetics.

[107]  Philip Raskin,et al.  The treatment of hypertension in adult patients with diabetes. , 2002, Diabetes care.

[108]  René M. Botnar,et al.  Coronary magnetic resonance angiography for the detection of coronary stenoses. , 2001, The New England journal of medicine.

[109]  W. Daniel,et al.  Noninvasive coronary angiography--an acceptable alternative? , 2001, The New England journal of medicine.

[110]  G. Bray,et al.  Effects of Diet and Sodium Intake on Blood Pressure: Subgroup Analysis of the DASH-Sodium Trial , 2001, Annals of Internal Medicine.

[111]  C. Ballantyne,et al.  Influence of Low High-Density Lipoprotein Cholesterol and Elevated Triglyceride on Coronary Heart Disease Events and Response to Simvastatin Therapy in 4S , 2001, Circulation.

[112]  R. Peters,et al.  Genetic Variation in Coagulation and Fibrinolytic Proteins and Their Relation With Acute Myocardial Infarction: A Systematic Review , 2001, Circulation.

[113]  I. Holme,et al.  High apolipoprotein B, low apolipoprotein A-I, and improvement in the prediction of fatal myocardial infarction (AMORIS study): a prospective study , 2001, The Lancet.

[114]  D. Altmann,et al.  Exploring the relationship between alcohol consumption and non-fatal or fatal stroke: a systematic review. , 2001, Addiction.

[115]  Daniel Levy,et al.  Assessment of frequency of progression to hypertension in non-hypertensive participants in the Framingham Heart Study: a cohort study , 2001, The Lancet.

[116]  J. Kastelein,et al.  The molecular basis of familial hypercholesterolemia in The Netherlands , 2001, Human Genetics.

[117]  D. Levy,et al.  Impact of High-Normal Blood Pressure on the Risk of Cardiovascular Disease , 2001 .

[118]  René M. Botnar,et al.  3D coronary vessel wall imaging utilizing a local inversion technique with spiral image acquisition , 2001, Magnetic resonance in medicine.

[119]  Chun Yuan,et al.  High-Resolution Magnetic Resonance Imaging of Normal and Atherosclerotic Human Coronary Arteries Ex Vivo , 2001, Journal of Investigative Medicine.

[120]  J. Ioannidis,et al.  Replication validity of genetic association studies , 2001, Nature Genetics.

[121]  J. Anderson,et al.  Obesity and disease management: effects of weight loss on comorbid conditions. , 2001, Obesity research.

[122]  S M Grundy,et al.  Improving coronary heart disease risk assessment in asymptomatic people: role of traditional risk factors and noninvasive cardiovascular tests. , 2001, Circulation.

[123]  V F Froelicher,et al.  Exercise standards for testing and training: a statement for healthcare professionals from the American Heart Association. , 2001, Circulation.

[124]  M. Woodward,et al.  Randomised trial of a perindopril-based blood pressure lowering regimen among 6,105 individuals with previous stroke or transient ischaemic attack , 2001 .

[125]  V. Fuster,et al.  AHA/ACC Guidelines for Preventing Heart Attack and Death in Patients With Atherosclerotic Cardiovascular Disease: 2001 update. A statement for healthcare professionals from the American Heart Association and the American College of Cardiology. , 2001, Journal of the American College of Cardiology.

[126]  B. Brenner,et al.  Effects of losartan on renal and cardiovascular outcomes in patients with type 2 diabetes and nephropathy. , 2001, The New England journal of medicine.

[127]  H. Parving,et al.  The effect of irbesartan on the development of diabetic nephropathy in patients with type 2 diabetes. , 2001, The New England journal of medicine.

[128]  P. Ades Cardiac rehabilitation and secondary prevention of coronary heart disease. , 2001, The New England journal of medicine.

[129]  E. Lewis,et al.  Renoprotective effect of the angiotensin-receptor antagonist irbesartan in patients with nephropathy due to type 2 diabetes. , 2001, The New England journal of medicine.

[130]  M. Criqui,et al.  Peripheral Arterial Disease Detection, Awareness, and Treatment in Primary Care , 2001 .

[131]  Roberto Sega,et al.  Alterations of Cardiac Structure in Patients With Isolated Office, Ambulatory, or Home Hypertension: Data From the General Population (Pressione Arteriose Monitorate E Loro Associazioni [PAMELA] Study) , 2001, Circulation.

[132]  Reza Emdad,et al.  Employee Effects of an Educational Program for Managers at an Insurance Company , 2001, Psychosomatic medicine.

[133]  G. MacGregor,et al.  Fortnightly review: Beneficial effects of potassium. , 2001, BMJ.

[134]  V. Pavlik,et al.  Characteristics of patients with uncontrolled hypertension in the United States. , 2001, The New England journal of medicine.

[135]  A. Coats,et al.  Exercise and heart failure. , 2001, Cardiology clinics.

[136]  S. Gielen,et al.  Effects of exercise training on vascular function and myocardial perfusion. , 2001, Cardiology clinics.

[137]  P. Ades,et al.  Exercise rehabilitation of older patients with cardiovascular disease. , 2001, Cardiology clinics.

[138]  S. Daniels Cardiovascular disease risk factors and atherosclerosis in children and adolescents , 2001, Current atherosclerosis reports.

[139]  J. Rumberger,et al.  Long-Term Prognostic Value of Coronary Calcification Detected by Electron-Beam Computed Tomography in Patients Undergoing Coronary Angiography , 2001, Circulation.

[140]  B. Wennerblom,et al.  Intensive home-based exercise training in cardiac rehabilitation increases exercise capacity and heart rate variability. , 2001, International journal of cardiology.

[141]  J. Gamble,et al.  Time sequence of the inhibition of endothelial adhesion molecule expression by reconstituted high density lipoproteins. , 2001, Atherosclerosis.

[142]  J. Buring,et al.  Abdominal and total adiposity and risk of coronary heart disease in men , 2001, International Journal of Obesity.

[143]  M. Laville,et al.  Perceived Job Stress but not Individual Cardiovascular Reactivity to Stress Is Related to Higher Blood Pressure at Work , 2001, Hypertension.

[144]  Paul M. Ridker,et al.  Measurement of C-reactive protein for the targeting of statin therapy in the primary prevention of acute coronary events. , 2001, The New England journal of medicine.

[145]  Frank Hu,et al.  The Effect of Fruit and Vegetable Intake on Risk for Coronary Heart Disease , 2001, Annals of Internal Medicine.

[146]  T. Lakka,et al.  Low Dietary Folate Intake Is Associated With an Excess Incidence of Acute Coronary Events: The Kuopio Ischemic Heart Disease Risk Factor Study , 2001, Circulation.

[147]  D. Mant,et al.  Cluster randomised controlled trial to compare three methods of promoting secondary prevention of coronary heart disease in primary care , 2001, BMJ : British Medical Journal.

[148]  S. Silber,et al.  Bedeutung der EKG-Triggerung mit dem Multi-Slice-CT zum Ausschluss einer Koronararterienverkalkung bei Personen ohne bekannte KHK , 2001, Herz.

[149]  L. Kuller,et al.  Lipid and blood pressure treatment goals for type 1 diabetes: 10-year incidence data from the Pittsburgh Epidemiology of Diabetes Complications Study. , 2001, Diabetes care.

[150]  Lee Hooper,et al.  Antioxidant strategy for cardiovascular disease , 2001, The Lancet.

[151]  W. Hiatt,et al.  Medical treatment of peripheral arterial disease and claudication. , 2001, The New England journal of medicine.

[152]  J. Danesh,et al.  Fibrin D-Dimer and Coronary Heart Disease: Prospective Study and Meta-Analysis , 2001, Circulation.

[153]  G. Gaetano,et al.  Drink in moderation, says consensus panel , 2001, The Lancet.

[154]  T. Valle,et al.  Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. , 2001, The New England journal of medicine.

[155]  S. Grundy Coronary calcium as a risk factor: role in global risk assessment. , 2001, Journal of the American College of Cardiology.

[156]  P. Elwood,et al.  Platelet tests in the prediction of myocardial infarction and ischaemic stroke: evidence from the Caerphilly Prospective Study , 2001, British journal of haematology.

[157]  H. Hecht,et al.  Electron beam tomography and National Cholesterol Education Program guidelines in asymptomatic women. , 2001, Journal of the American College of Cardiology.

[158]  Michael F. Oliver,et al.  Effects of atorvastatin on early recurrent ischemic events in acute coronary syndromes. The MIRACL study. , 2001, Indian heart journal.

[159]  R. Virmani,et al.  Coronary atherosclerosis in unheralded sudden coronary death under age 50: histo-pathologic comparison with 'healthy' subjects dying out of hospital. , 2001, Atherosclerosis.

[160]  S. Humphries,et al.  A molecular genetic service for diagnosing individuals with familial hypercholesterolaemia (FH) in the United Kingdom , 2001, European Journal of Human Genetics.

[161]  G. Lowe,et al.  C-Reactive Protein, Fibrin D-Dimer, and Incident Ischemic Heart Disease in the Speedwell Study: Are Inflammation and Fibrin Turnover Linked in Pathogenesis? , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[162]  L. Groop,et al.  Cardiovascular morbidity and mortality associated with the metabolic syndrome. , 2001, Diabetes care.

[163]  V. Salomaa,et al.  Prospective Study of Fibrinolytic Factors and Incident Coronary Heart Disease: The Atherosclerosis Risk in Communities (ARIC) Study , 2001, Arteriosclerosis, thrombosis, and vascular biology.

[164]  D. Wood,et al.  Clinical reality of coronary prevention guidelines: a comparison of EUROASPIRE I and II in nine countries , 2001, The Lancet.

[165]  Shah Ebrahim,et al.  Dietary fat intake and prevention of cardiovascular disease: systematic review , 2001, BMJ : British Medical Journal.

[166]  J. Tuomilehto,et al.  Urinary sodium excretion and cardiovascular mortality in Finland: a prospective study , 2001, The Lancet.

[167]  E. Feskens,et al.  Association between trans fatty acid intake and 10-year risk of coronary heart disease in the Zutphen Elderly Study: a prospective population-based study , 2001, The Lancet.

[168]  Martin G. Larson,et al.  Does the Relation of Blood Pressure to Coronary Heart Disease Risk Change With Aging?: The Framingham Heart Study , 2001, Circulation.

[169]  P. O'Malley,et al.  Do conventional risk factors predict subclinical coronary artery disease? Results from the Prospective Army Coronary Calcium Project. , 2001, American heart journal.

[170]  P. Wilson,et al.  Determinants of plasma total homocysteine concentration in the Framingham Offspring cohort. , 2001, The American journal of clinical nutrition.

[171]  E. Rimm,et al.  Genetic variation in alcohol dehydrogenase and the beneficial effect of moderate alcohol consumption on myocardial infarction. , 2001, The New England journal of medicine.

[172]  J. Blacher,et al.  Impact of Aortic Stiffness Attenuation on Survival of Patients in End-Stage Renal Failure , 2001, Circulation.

[173]  Renu Virmani,et al.  Healed Plaque Ruptures and Sudden Coronary Death: Evidence That Subclinical Rupture Has a Role in Plaque Progression , 2001, Circulation.

[174]  J. Pankow,et al.  Familial and genetic determinants of systemic markers of inflammation: the NHLBI family heart study. , 2001, Atherosclerosis.

[175]  H. Hecht,et al.  Relation of coronary artery calcium identified by electron beam tomography to serum lipoprotein levels and implications for treatment. , 2001, The American journal of cardiology.

[176]  M. Marmot,et al.  The relationship between job strain and coronary heart disease: evidence from an English sample of the working male population , 2001, Psychological Medicine.

[177]  P. O'Malley,et al.  C-reactive protein is not associated with the presence or extent of calcified subclinical atherosclerosis. , 2001, American heart journal.

[178]  D Wood,et al.  Established and emerging cardiovascular risk factors. , 2001, American heart journal.

[179]  A. Zanchetti,et al.  Renal function and intensive lowering of blood pressure in hypertensive participants of the hypertension optimal treatment (HOT) study. , 2001, Journal of the American Society of Nephrology : JASN.

[180]  L. Beilin,et al.  Long-chain omega 3 fatty acids, blood lipids and cardiovascular risk reduction , 2001, Current opinion in lipidology.

[181]  M. Reiser,et al.  Correlation of coronary calcification and angiographically documented stenoses in patients with suspected coronary artery disease: results of 1,764 patients. , 2001, Journal of the American College of Cardiology.

[182]  E. Sijbrands,et al.  Review of first 5 years of screening for familial hypercholesterolaemia in the Netherlands , 2001, The Lancet.

[183]  D. Pennell,et al.  Left Ventricular Hypertrophy With Exercise and ACE Gene Insertion/Deletion Polymorphism: A Randomized Controlled Trial With Losartan , 2001, Circulation.

[184]  M. Roncaglioni Low-dose aspirin and vitamin E in people at cardiovascular risk: a randomised trial in general Practice , 2001, The Lancet.

[185]  N. Wareham,et al.  Glycated haemoglobin, diabetes, and mortality in men in Norfolk cohort of European Prospective Investigation of Cancer and Nutrition (EPIC-Norfolk) , 2001, BMJ : British Medical Journal.

[186]  G. Bray,et al.  Effects on blood pressure of reduced dietary sodium and the Dietary Approaches to Stop Hypertension (DASH) diet , 2001 .

[187]  J. Hodgson,et al.  Non Pharmacologic Therapy and Lifestyle Factors in Hypertension , 2001, Blood pressure.

[188]  C. Boreham,et al.  The physical activity, fitness and health of children , 2001, Journal of sports sciences.

[189]  J. Després,et al.  Health consequences of visceral obesity , 2001, Annals of medicine.

[190]  D. Barker Fetal and infant origins of adult disease , 2001, Monatsschrift Kinderheilkunde.

[191]  David R. Wood,et al.  Lifestyle and risk factor management and use of drug therapies in coronary patients from 15 countries; principal results from EUROASPIRE II Euro Heart Survey Programme. , 2001, European heart journal.

[192]  R. Pate,et al.  Physical Activity Assessment in Children and Adolescents , 2001, Sports medicine.

[193]  E. Rimm,et al.  Alcohol’s Effects on the Risk for Coronary Heart Disease , 2001, Alcohol research & health : the journal of the National Institute on Alcohol Abuse and Alcoholism.

[194]  E. Feskens,et al.  Glucose tolerance and cardiovascular mortality: comparison of fasting and 2-hour diagnostic criteria. , 2001, Archives of internal medicine.

[195]  Neil Schneiderman,et al.  Marital Stress Worsens Prognosis in Women With Coronary Heart Disease , 2000 .

[196]  Jacqueline P Mitchell,et al.  Comparison of Novel Hemostatic Factors and Conventional Risk Factors for Prediction of Coronary Heart Disease , 2000, Circulation.

[197]  A. Murphy Guidelines for Cardiac Rehabilitation and Secondary Prevention Programmes , 2000 .

[198]  J. Reiber,et al.  Ultrasound Assessment of Atherosclerotic Vessel Wall Changes: Reproducibility of Intima-Media Thickness Measurements in Carotid and Femoral Arteries , 2000, Investigative radiology.

[199]  C. Loria,et al.  Serum folate and cardiovascular disease mortality among US men and women. , 2000, Archives of internal medicine.

[200]  René M. Botnar,et al.  Noninvasive Coronary Vessel Wall and Plaque Imaging With Magnetic Resonance Imaging , 2000, Circulation.

[201]  M. Rubens,et al.  Cross sectional study of differences in coronary artery calcification by socioeconomic status , 2000, BMJ : British Medical Journal.

[202]  J. Strong,et al.  Origin of atherosclerosis in childhood and adolescence. , 2000, The American journal of clinical nutrition.

[203]  A. Malliani,et al.  Modifications of Cardiac Autonomic Profile Associated With a Shift Schedule of Work , 2000, Circulation.

[204]  G Corrao,et al.  Alcohol and coronary heart disease: a meta-analysis. , 2000, Addiction.

[205]  Y. Arad,et al.  Prediction of coronary events with electron beam computed tomography. , 2000, Journal of the American College of Cardiology.

[206]  L. Shaw,et al.  The challenge of improving risk assessment in asymptomatic individuals: the additive prognostic value of electron beam tomography? , 2000, Journal of the American College of Cardiology.

[207]  R. Clarke,et al.  Vitamin Supplements and Cardiovascular Risk: Review of the Randomized Trials of Homocysteine-Lowering Vitamin Supplements , 2000, Seminars in thrombosis and hemostasis.

[208]  H. Hecht Practice guidelines for electron beam tomography: a report of the Society of Atherosclerosis Imaging. , 2000, The American journal of cardiology.

[209]  J. Danesh,et al.  Lipoprotein(a) and Coronary Heart Disease: Meta-Analysis of Prospective Studies , 2000, Circulation.

[210]  J. Gardin,et al.  Coronary artery calcium evaluation by electron beam computed tomography and its relation to new cardiovascular events. , 2000, The American journal of cardiology.

[211]  R. Carney,et al.  Change in Heart Rate and Heart Rate Variability During Treatment for Depression in Patients With Coronary Heart Disease , 2000, Psychosomatic medicine.

[212]  R. Holman,et al.  Association of glycaemia with macrovascular and microvascular complications of type 2 diabetes (UKPDS 35): prospective observational study , 2000, BMJ : British Medical Journal.

[213]  J. Denollet,et al.  Inadequate response to treatment in coronary heart disease : adverse effects of type D personality and younger age on 5-year prognosis and quality of life. , 2000, Circulation.

[214]  K. Yano,et al.  Ankle/brachial blood pressure in men >70 years of age and the risk of coronary heart disease. , 2000, The American journal of cardiology.

[215]  K. Schenck-Gustafsson,et al.  Job stress and the occupational gradient in coronary heart disease risk in women. The Stockholm Female Coronary Risk Study. , 2000, Social science & medicine.

[216]  G. Thorgeirsson,et al.  Follow-up study of patients randomized in the Scandinavian simvastatin survival study (4S) of cholesterol lowering. , 2000, The American journal of cardiology.

[217]  Samin K. Sharma,et al.  Noninvasive in vivo human coronary artery lumen and wall imaging using black-blood magnetic resonance imaging. , 2000, Circulation.

[218]  Giuseppe Mancia,et al.  Morbidity and mortality in patients randomised to double-blind treatment with a long-acting calcium-channel blocker or diuretic in the International Nifedipine GITS study: Intervention as a Goal in Hypertension Treatment (INSIGHT) , 2000, The Lancet.

[219]  Thomas Hedner,et al.  Randomised trial of effects of calcium antagonists compared with diuretics and β-blockers on cardiovascular morbidity and mortality in hypertension: the Nordic Diltiazem (NORDIL) study , 2000, The Lancet.

[220]  V F Froelicher,et al.  American College of Cardiology/American Heart Association Expert Consensus Document on electron-beam computed tomography for the diagnosis and prognosis of coronary artery disease. , 2000, Journal of the American College of Cardiology.

[221]  P. Ridker,et al.  Lack of association of C-reactive protein and coronary calcium by electron beam computed tomography in postmenopausal women: implications for coronary artery disease screening. , 2000, Journal of the American College of Cardiology.

[222]  K. Schenck-Gustafsson,et al.  Depressive symptoms and lack of social integration in relation to prognosis of CHD in middle-aged women. The Stockholm Female Coronary Risk Study. , 2000, European heart journal.

[223]  S. Kasim-Karakas,et al.  Changes in plasma lipoproteins during low-fat, high-carbohydrate diets: effects of energy intake. , 2000, The American journal of clinical nutrition.

[224]  A. Misra Risk Factors for Atherosclerosis in Young Individuals , 2000, Journal of cardiovascular risk.

[225]  D. Bunout,et al.  Low serum folate but normal homocysteine levels in patients with atherosclerotic vascular disease and matched healthy controls. , 2000, Nutrition.

[226]  K. Matthews,et al.  Association of hostility with coronary artery calcification in young adults: the CARDIA study. Coronary Artery Risk Development in Young Adults. , 2000, JAMA.

[227]  A. Zanchetti,et al.  Influence of gender and age on preventing cardiovascular disease by antihypertensive treatment and acetylsalicylic acid. The HOT study , 2000 .

[228]  A. Schmermund,et al.  Electron-beam computed tomography for detection of early signs of coronary arteriosclerosis. , 2000, European heart journal.

[229]  T. Lakka,et al.  Low serum folate concentrations are associated with an excess incidence of acute coronary events: the Kuopio Ischaemic Heart Disease Risk Factor Study , 2000, European Journal of Clinical Nutrition.

[230]  M. Mckee,et al.  The relation between alcohol and cardiovascular disease in Eastern Europe: explaining the paradox , 2000, Journal of epidemiology and community health.

[231]  M. Bourassa,et al.  Social support, depression, and mortality during the first year after myocardial infarction. , 2000, Circulation.

[232]  Barry R. Davis,et al.  Major cardiovascular events in hypertensive patients randomized to doxazosin vs chlorthalidone: the antihypertensive and lipid-lowering treatment to prevent heart attack trial (ALLHAT). ALLHAT Collaborative Research Group. , 2000, JAMA.

[233]  D. Cook,et al.  Effect of smoking cessation on mortality after myocardial infarction: meta-analysis of cohort studies. , 2000, Archives of internal medicine.

[234]  Richard Smith Vaccines and medicines for the world's poorest , 2000, BMJ : British Medical Journal.

[235]  G D Lowe,et al.  Haematocrit, viscosity, erythrocyte sedimentation rate: meta-analyses of prospective studies of coronary heart disease. , 2000, European heart journal.

[236]  René M. Botnar,et al.  Free‐breathing 3D coronary MRA: The impact of “Isotropic” image resolution , 2000, Journal of magnetic resonance imaging : JMRI.

[237]  R. Detrano,et al.  Prognostic value of coronary electron-beam computed tomography for coronary heart disease events in asymptomatic populations. , 2000, The American journal of cardiology.

[238]  M. Skolnick,et al.  Genetic localization to chromosome 1p32 of the third locus for familial hypercholesterolemia in a Utah kindred. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[239]  R. Virmani,et al.  A comparison of the Framingham risk index, coronary artery calcification, and culprit plaque morphology in sudden cardiac death. , 2000, Circulation.

[240]  Karla Kerlikowske,et al.  Risks of untreated and treated isolated systolic hypertension in the elderly: meta-analysis of outcome trials , 2000, The Lancet.

[241]  K. Fagerström,et al.  Diagnosis and treatment of nicotine dependence with emphasis on nicotine replacement therapy. A status report. , 2000, European heart journal.

[242]  A. Folsom,et al.  Carotid wall thickness is predictive of incident clinical stroke: the Atherosclerosis Risk in Communities (ARIC) study. , 2000, American journal of epidemiology.

[243]  T. Callister,et al.  Identification of patients at increased risk of first unheralded acute myocardial infarction by electron-beam computed tomography. , 2000, Circulation.

[244]  C. Cannon,et al.  Critical pathways : a review. Committee on Acute Cardiac Care, Council on Clinical Cardiology, American Heart Association. , 2000, Circulation.

[245]  Bruce H. R. Wolffenbuttel,et al.  Effects of ramipril on cardiovascular and microvascular outcomes in people with diabetes mellitus: results of the HOPE study and MICRO-HOPE substudy , 2000, The Lancet.

[246]  S. Yusuf,et al.  Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. , 2000 .

[247]  S. Yusuf,et al.  Vitamin E supplementation and cardiovascular events in high-risk patients. , 2000, The New England journal of medicine.

[248]  W. Kannel,et al.  Elevated systolic blood pressure as a cardiovascular risk factor. , 2000, The American journal of cardiology.

[249]  Philip Greenland,et al.  Prevention Conference V Beyond Secondary Prevention : Identifying the High-Risk Patient for Primary Prevention : Executive Summary , 2000 .

[250]  V. Fuster,et al.  Prevention Conference V: Beyond secondary prevention: identifying the high-risk patient for primary prevention: noninvasive tests of atherosclerotic burden: Writing Group III. , 2000, Circulation.

[251]  T. Wilt,et al.  Gemfibrozil for the Secondary Prevention of Coronary Heart Disease in Men with Low Levels of High-Density Lipoprotein Cholesterol , 2000 .

[252]  L. Smeeth,et al.  Commentary : DINS, PINS, and things-clinical and population perspectives on treatment effects , 2000 .

[253]  T Lauritzen,et al.  The ADDITION study: proposed trial of the cost-effectiveness of an intensive multifactorial intervention on morbidity and mortality among people with Type 2 diabetes detected by screening , 2000, International Journal of Obesity.

[254]  R. Virmani,et al.  Coronary calcification: insights from sudden coronary death victims , 2000, Zeitschrift für Kardiologie.

[255]  T. Rychlewski,et al.  Beneficial effect of short-term endurance training on glucose metabolism during rehabilitation after coronary bypass surgery. , 2000, Chest.

[256]  G. Lowe,et al.  Lifestyle and hemostatic risk factors for ischemic heart disease : the Caerphilly Study. , 2000, Arteriosclerosis, thrombosis, and vascular biology.

[257]  J. Larosa,et al.  Effect of statins on risk of coronary disease: a meta-analysis of randomized controlled trials. , 1999, JAMA.

[258]  E. Rimm,et al.  Moderate alcohol intake and lower risk of coronary heart disease: meta-analysis of effects on lipids and haemostatic factors , 1999, BMJ.

[259]  J. McMurray,et al.  Major β blocker mortality trials in chronic heart failure: a critical review , 1999 .

[260]  G. Mancia,et al.  Task force V: White-coat hypertension , 1999 .

[261]  G. Fraser,et al.  Body weight and mortality among adults who never smoked. , 1999, American journal of epidemiology.

[262]  J. Manson,et al.  Dietary saturated fats and their food sources in relation to the risk of coronary heart disease in women. , 1999, The American journal of clinical nutrition.

[263]  Mario Pirastu,et al.  Population choice in mapping genes for complex diseases , 1999, Nature Genetics.

[264]  T. Hedner,et al.  Randomised trial of old and new antihypertensive drugs in elderly patients: cardiovascular mortality and morbidity the Swedish Trial in Old Patients with Hypertension-2 study , 1999, The Lancet.

[265]  V. Fuster,et al.  The diagnostic accuracy of ex vivo MRI for human atherosclerotic plaque characterization. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[266]  M. Laakso,et al.  Men and Women , 1901 .

[267]  I. Jialal,et al.  GISSI-Prevenzione trial , 1999, The Lancet.

[268]  M. Awerbuch Non-specific arm pain , 1999, The Lancet.

[269]  M. Cabana,et al.  Why don't physicians follow clinical practice guidelines? A framework for improvement. , 1999, JAMA.

[270]  M. Thun,et al.  Body-mass index and mortality in a prospective cohort of U.S. adults. , 1999, The New England journal of medicine.

[271]  D Spiegelman,et al.  Fruit and vegetable intake in relation to risk of ischemic stroke. , 1999, JAMA.

[272]  S M Grundy,et al.  Assessment of cardiovascular risk by use of multiple-risk-factor assessment equations: a statement for healthcare professionals from the American Heart Association and the American College of Cardiology. , 1999, Circulation.

[273]  I. Rosenberg,et al.  Serum Total Homocysteine Concentrations in the Third National Health and Nutrition Examination Survey (19911994): Population Reference Ranges and Contribution of Vitamin Status to High Serum Concentrations , 1999, Annals of Internal Medicine.

[274]  M. A. Sellers,et al.  Prognostic importance of lower extremity arterial disease in patients undergoing coronary revascularization in the Bypass Angioplasty Revascularization Investigation (BARI). , 1999, Journal of the American College of Cardiology.

[275]  K. Bailey,et al.  Independent and incremental value of coronary artery calcium for predicting the extent of angiographic coronary artery disease: comparison with cardiac risk factors and radionuclide perfusion imaging. , 1999, Journal of the American College of Cardiology.

[276]  J. Meulman,et al.  A meta-analysis of psychoeducational programs for coronary heart disease patients. , 1999 .

[277]  T Suzuki,et al.  Process of progression of coronary artery lesions from mild or moderate stenosis to moderate or severe stenosis: A study based on four serial coronary arteriograms per year. , 1999, Circulation.

[278]  E. Feskens,et al.  Glucose tolerance and mortality: comparison of WHO and American Diabetic Association diagnostic criteria , 1999, The Lancet.

[279]  GISSI-Prevenzione Investigators,et al.  Dietary supplementation with n-3 polyunsaturated fatty acids and vitamin E after myocardial infarction: results of the GISSI-Prevenzione trial , 1999, The Lancet.

[280]  T. Wilt,et al.  Gemfibrozil for the secondary prevention of coronary heart disease in men with low levels of high-density lipoprotein cholesterol. Veterans Affairs High-Density Lipoprotein Cholesterol Intervention Trial Study Group. , 1999, The New England journal of medicine.

[281]  S. Rich,et al.  Utility of electron beam computed tomography to stratify patients presenting to the emergency room with chest pain. , 1999, The American journal of cardiology.

[282]  Barry Lewis,et al.  Coronary heart disease: reducing the risk: the scientific background to primary and secondary prevention of coronary heart disease. A worldwide view. International Task force for the Prevention of Coronary Heart disease. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[283]  M. Schroll,et al.  Urinary albumin excretion. An independent predictor of ischemic heart disease. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[284]  D. Levy,et al.  Is pulse pressure useful in predicting risk for coronary heart Disease? The Framingham heart study. , 1999, Circulation.

[285]  Harlan M. Krumholz,et al.  Sex-Based Differences in Early Mortality after Myocardial Infarction , 1999 .

[286]  I. Bata,et al.  The short-term effects of a hostility-reduction intervention on male coronary heart disease patients. , 1999, Health psychology : official journal of the Division of Health Psychology, American Psychological Association.

[287]  René M. Botnar,et al.  Improved coronary artery definition with T2-weighted, free-breathing, three-dimensional coronary MRA. , 1999, Circulation.

[288]  L. Smeeth,et al.  Numbers needed to treat derived from meta-analyses—sometimes informative, usually misleading , 1999, BMJ.

[289]  R. Holman,et al.  Glycemic control with diet, sulfonylurea, metformin, or insulin in patients with type 2 diabetes mellitus: progressive requirement for multiple therapies (UKPDS 49). UK Prospective Diabetes Study (UKPDS) Group. , 1999, JAMA.

[290]  Harry Hemingway,et al.  Evidence based cardiology: psychosocial factors in the aetiology and prognosis of coronary heart disease. Systematic review of prospective cohort studies. , 1999, BMJ.

[291]  L E Ginzton,et al.  Coronary calcium does not accurately predict near-term future coronary events in high-risk adults. , 1999, Circulation.

[292]  S. Grundy Age as a risk factor: you are as old as your arteries. , 1999, The American journal of cardiology.

[293]  A. Folsom,et al.  Dietary flavonoid intake and risk of cardiovascular disease in postmenopausal women. , 1999, American journal of epidemiology.

[294]  S. Grundy Hypertriglyceridemia, insulin resistance, and the metabolic syndrome. , 1999, The American journal of cardiology.

[295]  J. Manson,et al.  Dietary intake of α-linolenic acid and risk of fatal ischemic heart disease among women , 1999 .

[296]  M. Kleinman,et al.  The exercise-induced oxidative stress paradox: the effects of physical exercise training. , 1999, The American journal of the medical sciences.

[297]  Owens,et al.  Repaglinide: a new short‐acting insulinotropic agent for the treatment of Type 2 diabetes , 1999, European journal of clinical investigation.

[298]  C. Junien,et al.  A third major locus for autosomal dominant hypercholesterolemia maps to 1p34.1-p32. , 1999, American journal of human genetics.

[299]  J. Blumenthal,et al.  Impact of psychological factors on the pathogenesis of cardiovascular disease and implications for therapy. , 1999, Circulation.

[300]  G. Lowe,et al.  Factor VIII, von Willebrand factor and the risk of major ischaemic heart disease in the Caerphilly Heart Study , 1999, British journal of haematology.

[301]  C. Bulpitt,et al.  Effects of Calcium-Channel Blockade in Older Patients with Diabetes and Systolic Hypertension , 1999 .

[302]  K. Schenck-Gustafsson,et al.  Potential explanations for the educational gradient in coronary heart disease: a population-based case-control study of Swedish women. , 1999, American journal of public health.

[303]  O. Pedersen,et al.  Intensified multifactorial intervention in patients with type 2 diabetes mellitus and microalbuminuria: the Steno type 2 randomised study , 1999, The Lancet.

[304]  J. Grimshaw,et al.  Potential benefits, limitations, and harms of clinical guidelines , 1999, BMJ.

[305]  L. Niskanen,et al.  Effect of angiotensin-converting-enzyme inhibition compared with conventional therapy on cardiovascular morbidity and mortality in hypertension: the Captopril Prevention Project (CAPPP) randomised trial , 1999, The Lancet.

[306]  L. Wilhelmsen,et al.  Body weight and weight gain during adult life in men in relation to coronary heart disease and mortality. A prospective population study. , 1999, European heart journal.

[307]  G. Guyatt,et al.  Systematic review on the risk and benefit of different cholesterol-lowering interventions. , 1999, Arteriosclerosis, thrombosis, and vascular biology.

[308]  R. Kronmal,et al.  Carotid-artery intima and media thickness as a risk factor for myocardial infarction and stroke in older adults. Cardiovascular Health Study Collaborative Research Group. , 1999, The New England journal of medicine.

[309]  J. Tuomilehto,et al.  Is fasting glucose sufficient to define diabetes? Epidemiological data from 20 European studies , 1999 .

[310]  S. Neubauer,et al.  Three-dimensional MR coronary angiography using the navigator technique compared with conventional coronary angiography. , 1999, AJR. American journal of roentgenology.

[311]  T. Sheldon,et al.  What role for statins? A review and economic model. , 1999, Health technology assessment.

[312]  T. Callister,et al.  Effect of HMG-CoA reductase inhibitors on coronary artery disease as assessed by electron-beam computed tomography. , 1998, The New England journal of medicine.

[313]  A. Folsom,et al.  Body Mass Index, Waist/Hip Ratio, and Coronary Heart Disease Incidence in African Americans and Whites , 1998 .

[314]  J. Murgo,et al.  Modulatory impact of cardiac rehabilitation on hyperhomocysteinemia in patients with coronary artery disease and "normal" lipid levels. , 1998, The American journal of cardiology.

[315]  G A Colditz,et al.  Abdominal adiposity and coronary heart disease in women. , 1998, JAMA.

[316]  J A Staessen,et al.  Comparison of active treatment and placebo in older Chinese patients with isolated systolic hypertension , 1998, Journal of hypertension.

[317]  W A Kalender,et al.  Electrocardiogram-correlated image reconstruction from subsecond spiral computed tomography scans of the heart. , 1998, Medical physics.

[318]  R. Collins,et al.  Prevention of cardiovascular events and death with pravastatin in patients with coronary heart disease and a broad range of initial cholesterol levels. , 1998, The New England journal of medicine.

[319]  Barry J. Davis,et al.  Effect of Pravastatin on Cardiovascular Events in Older Patients with Myocardial Infarction and Cholesterol Levels in the Average Range: Results of the Cholesterol and Recurrent Events (CARE) Trial , 1998, Annals of Internal Medicine.

[320]  A. Zanchetti,et al.  The Verapamil in Hypertension and Atherosclerosis Study (VHAS): Results of long‐term randomized treatment with either verapamil or chlorthalidone on carotid intima‐media thickness , 1998, Journal of hypertension.

[321]  S. Knox,et al.  SOCIAL ISOLATION AND CARDIOVASCULAR DISEASE: AN ATHEROSCLEROTIC PATHWAY? , 1998, Psychoneuroendocrinology.

[322]  G. Mancia,et al.  Prevention of coronary heart disease in clinical practice: recommendations of the Second Joint Task Force of European and other Societies on Coronary Prevention. , 1998, Atherosclerosis.

[323]  J. Dietschy,et al.  Centripetal cholesterol flux to the liver is dictated by events in the peripheral organs and not by the plasma high density lipoprotein or apolipoprotein A-I concentration. , 1998, Journal of lipid research.

[324]  J. Marrugat,et al.  Mortality Differences between Men and Women following First Myocardial Infarction , 2022 .

[325]  B. Cox,et al.  The effect of a low-fat, high-carbohydrate diet on serum high density lipoprotein cholesterol and triglyceride , 1998, European Journal of Clinical Nutrition.

[326]  Siep Thomas,et al.  Attributes of clinical guidelines that influence use of guidelines in general practice: observational study , 1998, BMJ.

[327]  Philip D. Harvey,et al.  Tight blood pressure control and risk of macrovascular and microvascular complications in type 2 diabetes: UKPDS 38 , 1998, BMJ.

[328]  R. Holman,et al.  Intensive blood-glucose control with sulphonylureas or insulin compared with conventional treatment and risk of complications in patients with type 2 diabetes (UKPDS 33). UK Prospective Diabetes Study (UKPDS) Group. , 1998 .

[329]  R. Holman,et al.  Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34) , 1998, The Lancet.

[330]  T. Callister,et al.  Coronary artery disease: improved reproducibility of calcium scoring with an electron-beam CT volumetric method. , 1998, Radiology.

[331]  H. King,et al.  Global Burden of Diabetes, 1995–2025: Prevalence, numerical estimates, and projections , 1998, Diabetes Care.

[332]  L. Alfredsson,et al.  High effort, low reward, and cardiovascular risk factors in employed Swedish men and women: baseline results from the WOLF Study. , 1998, Journal of epidemiology and community health.

[333]  J. Seidell,et al.  Selection of anthropometric indicators for classification of abdominal fatness— a critical review , 1998, International Journal of Obesity.

[334]  M. Law,et al.  By how much does fruit and vegetable consumption reduce the risk of ischaemic heart disease? , 1998, European Journal of Clinical Nutrition.

[335]  T. Byers,et al.  Serum folate and chronic disease risk: findings from a cohort of United States adults. , 1998, International journal of epidemiology.

[336]  M. Laakso,et al.  Mortality from coronary heart disease in subjects with type 2 diabetes and in nondiabetic subjects with and without prior myocardial infarction. , 1998, The New England journal of medicine.

[337]  A. Folsom,et al.  Prospective study of coronary heart disease incidence in relation to fasting total homocysteine, related genetic polymorphisms, and B vitamins: the Atherosclerosis Risk in Communities (ARIC) study. , 1998, Circulation.

[338]  T. Hedner,et al.  Survival in treated hypertension: follow up study after two decades , 1998, BMJ.

[339]  P. Zimmet,et al.  Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO Consultation , 1998, Diabetic medicine : a journal of the British Diabetic Association.

[340]  Joël Ménard,et al.  Effects of intensive blood-pressure lowering and low-dose aspirin in patients with hypertension: principal results of the Hypertension Optimal Treatment (HOT) randomised trial , 1998, The Lancet.

[341]  R. Williams Lower socioeconomic status and increased mortality: early childhood roots and the potential for successful interventions. , 1998, JAMA.

[342]  L. Mosca,et al.  Greater dietary intake of simple carbohydrate is associated with lower concentrations of high-density-lipoprotein cholesterol in hypercholesterolemic children. , 1998, The American journal of clinical nutrition.

[343]  P. Korner,et al.  Assessment of prevalence of left ventricular hypertrophy in hypertension. , 1998, Journal of hypertension.

[344]  S Goya Wannamethee,et al.  Changes in physical activity, mortality, and incidence of coronary heart disease in older men , 1998, The Lancet.

[345]  A. Gotto,et al.  Primary prevention of acute coronary events with lovastatin in men and women with average cholesterol levels: results of AFCAPS/TexCAPS. Air Force/Texas Coronary Atherosclerosis Prevention Study. , 1998, JAMA.

[346]  R J Glynn,et al.  C-reactive protein adds to the predictive value of total and HDL cholesterol in determining risk of first myocardial infarction. , 1998, Circulation.

[347]  R Peto,et al.  Association of fibrinogen, C-reactive protein, albumin, or leukocyte count with coronary heart disease: meta-analyses of prospective studies. , 1998, JAMA.

[348]  G. Thorgeirsson,et al.  Lipoprotein changes and reduction in the incidence of major coronary heart disease events in the Scandinavian Simvastatin Survival Study (4S) , 1998, Circulation.

[349]  P. Macfarlane,et al.  Influence of pravastatin and plasma lipids on clinical events in the West of Scotland Coronary Prevention Study (WOSCOPS). , 1998, Circulation.

[350]  B. Davis,et al.  Relationship between plasma LDL concentrations during treatment with pravastatin and recurrent coronary events in the Cholesterol and Recurrent Events trial. , 1998, Circulation.

[351]  S. Grundy,et al.  Statin trials and goals of cholesterol-lowering therapy. , 1998, Circulation.

[352]  J. Vestbo,et al.  Smoking and risk of myocardial infarction in women and men: longitudinal population study , 1998, BMJ.

[353]  M. Budoff,et al.  Coronary calcium and standard risk factors in symptomatic patients referred for coronary angiography. , 1998, American heart journal.

[354]  J. Meigs,et al.  Metabolic Risk Factors Worsen Continuously across the Spectrum of Nondiabetic Glucose Tolerance: The Framingham Offspring Study , 1998, Annals of Internal Medicine.

[355]  G. Malfatto,et al.  Effects of cardiac rehabilitation and beta-blocker therapy on heart rate variability after first acute myocardial infarction. , 1998, The American journal of cardiology.

[356]  L. Wilhelmsen,et al.  Diabetes and Long-Term Risk of Mortality From Coronary and Other Causes in Middle-Aged Swedish Men: A general population study , 1998, Diabetes Care.

[357]  T. Lehtimäki,et al.  Linkage of familial combined hyperlipidaemia to chromosome 1q21–q23 , 1998, Nature Genetics.

[358]  V. Fuster,et al.  Acute coronary syndromes: unstable angina and non-Q-wave myocardial infarction. , 1998, Circulation.

[359]  H. Hein,et al.  Triglyceride concentration and ischemic heart disease: an eight-year follow-up in the Copenhagen Male Study. , 1998, Circulation.

[360]  Christianna S. Williams,et al.  Prognostic importance of emotional support for elderly patients hospitalized with heart failure. , 1998, Circulation.

[361]  R J Havel,et al.  Rationale for use of non-high-density lipoprotein cholesterol rather than low-density lipoprotein cholesterol as a tool for lipoprotein cholesterol screening and assessment of risk and therapy. , 1998, The American journal of cardiology.

[362]  J. Manson,et al.  Folate and vitamin B6 from diet and supplements in relation to risk of coronary heart disease among women. , 1998, JAMA.

[363]  R. Schwartz,et al.  Coronary artery apoptosis is increased in a porcine model of experimental hypercholesterolemia , 1998 .

[364]  D. Wood European Action on Secondary Prevention by Intervention to Reduce Events , 1998 .

[365]  S. Vollset,et al.  Major lifestyle determinants of plasma total homocysteine distribution: the Hordaland Homocysteine Study. , 1998, The American journal of clinical nutrition.

[366]  G. Assmann,et al.  The Münster Heart Study (PROCAM). Results of follow-up at 8 years. , 1998, European heart journal.

[367]  A. Zwinderman,et al.  −455G/A Polymorphism of the β-Fibrinogen Gene is Associated With the Progression of Coronary Atherosclerosis in Symptomatic Men , 1998 .

[368]  Jenny Field,et al.  General practitioners' perceptions of the route to evidence based medicine: a questionnaire survey , 1998, BMJ.

[369]  A. Piazza,et al.  Plasma activity and insertion/deletion polymorphism of angiotensin I-converting enzyme: a major risk factor and a marker of risk for coronary stent restenosis. , 1998, Circulation.

[370]  G. Guyatt,et al.  Effect of HMGcoA Reductase Inhibitors on Stroke , 1998, Annals of Internal Medicine.

[371]  G. Howard,et al.  Cigarette smoking and progression of atherosclerosis: The Atherosclerosis Risk in Communities (ARIC) Study. , 1998, JAMA.

[372]  G. Smith,et al.  Meta-analysis Spurious precision? Meta-analysis of observational studies , 1998, BMJ.

[373]  S. Schanberg,et al.  Neuroendocrine, Cardiovascular, and Emotional Responses of Hostile Men: The Role of Interpersonal Challenge , 1998, Psychosomatic medicine.

[374]  C. Gohlke-Bärwolf,et al.  Cardiac rehabilitation: where are we going? , 1998, European heart journal.

[375]  J Siegrist,et al.  Two alternative job stress models and the risk of coronary heart disease. , 1998, American journal of public health.

[376]  P. Elwood,et al.  Fibrin D-dimer, Tissue Plasminogen Activator, Plasminogen Activator Inhibitor, and the Risk of Major Ischaemic Heart Disease in the Caerphilly Study , 1998, Thrombosis and Haemostasis.

[377]  S. Ebrahim Detection, adherence and control of hypertension for the prevention of stroke: a systematic review. , 1998, Health technology assessment.

[378]  W. Edwards,et al.  Arterial calcification and not lumen stenosis is highly correlated with atherosclerotic plaque burden in humans: a histologic study of 723 coronary artery segments using nondecalcifying methodology. , 1998, Journal of the American College of Cardiology.

[379]  T. Ogihara,et al.  Meta-analysis of association of insertion/deletion polymorphism of angiotensin I-converting enzyme gene with diabetic nephropathy and retinopathy , 1998, Diabetologia.

[380]  S. Haffner,et al.  Development of the multiple metabolic syndrome: an epidemiologic perspective. , 1998, Epidemiologic reviews.

[381]  Alan D. Lopez,et al.  Alcohol consumption and mortality among middle-aged and elderly U.S. adults. , 1997, The New England journal of medicine.

[382]  T. Lam,et al.  PASSIVE SMOKING AND CORONARY HEART DISEASE: A BRIEF REVIEW , 1997, Clinical and experimental pharmacology & physiology.

[383]  O. Wiklund,et al.  Cholesterol reduction and clinical benefit. Are there limits to our expectations? , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[384]  G A Colditz,et al.  Dietary fat intake and the risk of coronary heart disease in women. , 1997, The New England journal of medicine.

[385]  T. Dwyer,et al.  Differences in HDL cholesterol concentrations in Japanese, American, and Australian children. , 1997, Circulation.

[386]  R. Coleman,et al.  Stress management and exercise training in cardiac patients with myocardial ischemia : Effects on prognosis and evaluation of mechanisms , 1997 .

[387]  G. Schuler,et al.  Attenuated progression of coronary artery disease after 6 years of multifactorial risk intervention: role of physical exercise. , 1997, Circulation.

[388]  N J Wald,et al.  Environmental tobacco smoke exposure and ischaemic heart disease: an evaluation of the evidence , 1997, BMJ.

[389]  J. Salonen,et al.  Beer binging and mortality: results from the kuopio ischaemic heart disease risk factor study, a prospective population based study , 1997, BMJ.

[390]  A. Folsom,et al.  Association of coronary heart disease incidence with carotid arterial wall thickness and major risk factors: the Atherosclerosis Risk in Communities (ARIC) Study, 1987-1993. , 1997, American journal of epidemiology.

[391]  C. Sempos,et al.  Alcohol consumption and coronary heart disease morbidity and mortality. , 1997, American journal of epidemiology.

[392]  B. Penninx,et al.  Effects of social support and personal coping resources on mortality in older age: the Longitudinal Aging Study Amsterdam. , 1997, American journal of epidemiology.

[393]  Jan A Staessen,et al.  Randomised double-blind comparison of placebo and active treatment for older patients with isolated systolic hypertension , 1997, The Lancet.

[394]  Dwyer Jh EXPOSURE TO ENVIRONMENTAL TOBACCO SMOKE AND CORONARY RISK , 1997 .

[395]  D. Grönemeyer,et al.  Coronary artery calcium in acute coronary syndromes: a comparative study of electron-beam computed tomography, coronary angiography, and intracoronary ultrasound in survivors of acute myocardial infarction and unstable angina. , 1997, Circulation.

[396]  S. Schanberg,et al.  The Relationship Between Hostility and beta-Adrenergic Receptor Physiology in Healthy Young Males , 1997, Psychosomatic medicine.

[397]  T. Sheldon,et al.  Effective management of obesity. , 1997, Quality in health care : QHC.

[398]  A. Levey,et al.  Effect of angiotensin-converting enzyme inhibitors on the progression of nondiabetic renal disease: a meta-analysis of randomized trials. Angiotensin-Converting-Enzyme Inhibition and Progressive Renal Disease Study Group. , 1997, Annals of internal medicine.

[399]  A. Folsom,et al.  Prospective study of hemostatic factors and incidence of coronary heart disease: the Atherosclerosis Risk in Communities (ARIC) Study. , 1997, Circulation.

[400]  J. Danesh,et al.  Chronic infections and coronary heart disease: is there a link? , 1997, The Lancet.

[401]  S. Haffner,et al.  Insulin resistance implications for type II diabetes mellitus and coronary heart disease. , 1997, The American journal of medicine.

[402]  M. Härmä,et al.  Shift work, occupation and coronary heart disease over 6 years of follow-up in the Helsinki Heart Study. , 1997, Scandinavian journal of work, environment & health.

[403]  G. Assmann,et al.  Coagulation factor VII and the risk of coronary heart disease in healthy men. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[404]  D Kromhout,et al.  The burden of cardiovascular diseases mortality in Europe. Task Force of the European Society of Cardiology on Cardiovascular Mortality and Morbidity Statistics in Europe. , 1997, European heart journal.

[405]  C. Hennekens,et al.  Cholesterol lowering with statin drugs, risk of stroke, and total mortality. An overview of randomized trials. , 1997, JAMA.

[406]  K. McPherson,et al.  Impact of postmenopausal hormone therapy on cardiovascular events and cancer: pooled data from clinical trials , 1997, BMJ.

[407]  T. Raghunathan,et al.  Myocardial infarction in young women in relation to plasma total homocysteine, folate, and a common variant in the methylenetetrahydrofolate reductase gene. , 1997, Circulation.

[408]  A S Leon,et al.  Leisure Time Physical Activity and the 16-Year Risks of Mortality from Coronary Heart Disease and All-Causes in the Multiple Risk Factor Intervention Trial (MRFIT) , 1997, International journal of sports medicine.

[409]  A. Folsom,et al.  Physical activity and incidence of coronary heart disease in middle-aged women and men. , 1997, Medicine and science in sports and exercise.

[410]  J. Salonen,et al.  Workplace demands, economic reward, and progression of carotid atherosclerosis. , 1997, Circulation.

[411]  P. Heidenreich,et al.  Effect of beta-blockade on mortality in patients with heart failure: a meta-analysis of randomized clinical trials. , 1997, Journal of the American College of Cardiology.

[412]  C. Furberg,et al.  Reductase inhibitor monotherapy and stroke prevention. , 1997, Archives of internal medicine.

[413]  S. Ripatti,et al.  Randomised trial of α-tocopherol and β-carotene supplements on incidence of major coronary events in men with previous myocardial infarction , 1997, The Lancet.

[414]  J. Witteman,et al.  Plasma homocysteine as a risk factor for vascular disease. The European Concerted Action Project. , 1997, JAMA.

[415]  A. Avenell,et al.  Systematic review of randomised controlled trials , 2018 .

[416]  A. Gardemann,et al.  Positive Association of the β Fibrinogen H1/H2 Gene Variation to Basal Fibrinogen Levels and to the Increase in Fibrinogen Concentration during Acute Phase Reaction but not to Coronary Artery Disease and Myocardial Infarction , 1997, Thrombosis and Haemostasis.

[417]  C. Pieper,et al.  Psychosocial correlates of job strain in a sample of working women. , 1997, Archives of general psychiatry.

[418]  Bruce T. Smith,et al.  Plasma lipid and lipoprotein responses to dietary fat and cholesterol: a meta-analysis. , 1997, The American journal of clinical nutrition.

[419]  J. Manson,et al.  A prospective study of body mass index, weight change, and risk of stroke in women. , 1997, JAMA.

[420]  W C Willett,et al.  Intake of fatty acids and risk of coronary heart disease in a cohort of Finnish men. The Alpha-Tocopherol, Beta-Carotene Cancer Prevention Study. , 1997, American journal of epidemiology.

[421]  J. Witteman,et al.  Plasma total homocysteine, B vitamins, and risk of coronary atherosclerosis. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[422]  R. Virmani,et al.  Coronary risk factors and plaque morphology in men with coronary disease who died suddenly. , 1997, The New England journal of medicine.

[423]  M. Jauhiainen,et al.  Stearic acid, trans fatty acids, and dairy fat: effects on serum and lipoprotein lipids, apolipoproteins, lipoprotein(a), and lipid transfer proteins in healthy subjects. , 1997, The American journal of clinical nutrition.

[424]  P. Whelton,et al.  End-stage renal disease in African-American and white men. 16-year MRFIT findings. , 1997, JAMA.

[425]  G. Bray,et al.  A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. , 1997, The New England journal of medicine.

[426]  Terje R Pedersen,et al.  Cholesterol Lowering With Simvastatin Improves Prognosis of Diabetic Patients With Coronary Heart Disease: A subgroup analysis of the Scandinavian Simvastatin Survival Study (4S) , 1997, Diabetes Care.

[427]  B. Howard,et al.  Effects of Diet and Exercise in Preventing NIDDM in People With Impaired Glucose Tolerance: The Da Qing IGT and Diabetes Study , 1997, Diabetes Care.

[428]  E. Feskens,et al.  Antioxidant flavonols and coronary heart disease risk , 1997, The Lancet.

[429]  L. Chambless,et al.  The Relation of Alcohol Intake to Coronary Heart Disease and All‐Cause Mortality in a Beer‐Drinking Population , 1997, Epidemiology.

[430]  V. Fuster,et al.  Water diffusion properties of human atherosclerosis and thrombosis measured by pulse field gradient nuclear magnetic resonance. , 1997, Arteriosclerosis, thrombosis, and vascular biology.

[431]  G. Bakris,et al.  Effect of calcium channel or beta-blockade on the progression of diabetic nephropathy in African Americans. , 1997, Hypertension.

[432]  A. van Rossum,et al.  Clinical utility of two-dimensional magnetic resonance angiography in detecting coronary artery disease. , 1997, European heart journal.

[433]  Roberto Sega,et al.  Blood-pressure control in the hypertensive population , 1997, The Lancet.

[434]  A. Levey,et al.  Achievement and safety of a low blood pressure goal in chronic renal disease. The Modification of Diet in Renal Disease Study Group. , 1997, Hypertension.

[435]  U. Goldbourt,et al.  Physical activity, long-term CHD mortality and longevity: a review of studies over the last 30 years. , 1997, World review of nutrition and dietetics.

[436]  L. Wilhelmsen,et al.  Physical activity protects against coronary death and deaths from all causes in middle-aged men. Evidence from a 20-year follow-up of the primary prevention study in Göteborg. , 1997, Annals of epidemiology.

[437]  B. Davis,et al.  Effect of diuretic-based antihypertensive treatment on cardiovascular disease risk in older diabetic patients with isolated systolic hypertension. Systolic Hypertension in the Elderly Program Cooperative Research Group. , 1996, JAMA.

[438]  E. Rimm,et al.  Body size and fat distribution as predictors of stroke among US men. , 1996, American journal of epidemiology.

[439]  G. Diamond,et al.  Does coronary artery screening by electron beam computed tomography motivate potentially beneficial lifestyle behaviors? , 1996, The American journal of cardiology.

[440]  J. Salonen,et al.  Do cardiovascular risk factors explain the relation between socioeconomic status, risk of all-cause mortality, cardiovascular mortality, and acute myocardial infarction? , 1996, American journal of epidemiology.

[441]  G. Mancia,et al.  Considerations on current and future trials in hypertension. , 1996, Blood pressure.

[442]  B. Davis,et al.  The effect of pravastatin on coronary events after myocardial infarction in patients with average cholesterol levels. Cholesterol and Recurrent Events Trial investigators. , 1996, The New England journal of medicine.

[443]  A. Leaf,et al.  Antiarrhythmic effects of polyunsaturated fatty acids. Recent studies. , 1996, Circulation.

[444]  P. Wilson,et al.  Apolipoprotein E alleles and risk of coronary disease. A meta-analysis. , 1996, Arteriosclerosis, thrombosis, and vascular biology.

[445]  J. Manson,et al.  Birth weight and adult hypertension and obesity in women. , 1996, Circulation.

[446]  V. Fuster,et al.  Coronary artery calcification: pathophysiology, epidemiology, imaging methods, and clinical implications. A statement for health professionals from the American Heart Association. Writing Group. , 1996, Circulation.

[447]  G. Mancia,et al.  White-coat hypertension: misnomers, misconceptions and misunderstandings. What should we do next? , 1996, Journal of hypertension.

[448]  N. Samani,et al.  A meta-analysis of the association of the deletion allele of the angiotensin-converting enzyme gene with myocardial infarction. , 1996, Circulation.

[449]  M. Laakso Insulin resistance and coronary heart disease , 1996, Current opinion in lipidology.

[450]  M. Knuiman,et al.  Microalbuminuria in type 2 diabetes: an independent predictor of cardiovascular mortality. , 1996, Australian and New Zealand journal of medicine.

[451]  Steven N. Blair,et al.  Influences of Cardiorespiratory Fitness and Other Precursors on Cardiovascular Disease and All-Cause Mortality in Men and Women , 1996 .

[452]  E. Rimm,et al.  Dietary fat and risk of coronary heart disease in men: cohort follow up study in the United States , 1996, BMJ.

[453]  C. Sylvén,et al.  The DD genotype of the angiotensin-converting enzyme gene is associated with increased mortality in idiopathic heart failure. , 1996, Journal of the American College of Cardiology.

[454]  H. Morrison,et al.  Serum folate and risk of fatal coronary heart disease. , 1996, JAMA.

[455]  Y. Arad,et al.  Predictive value of electron beam computed tomography of the coronary arteries. 19-month follow-up of 1173 asymptomatic subjects. , 1996, Circulation.

[456]  Y. Itzchak,et al.  Absence of coronary calcification on double-helical CT scans: predictor of angiographically normal coronary arteries in elderly women? , 1996, Radiology.

[457]  R. Mensink,et al.  Comparison of the effects of diets enriched in lauric, palmitic, or oleic acids on serum lipids and lipoproteins in healthy women and men. , 1996, The American journal of clinical nutrition.

[458]  M Hillsdon,et al.  A systematic review of physical activity promotion strategies. , 1996, British journal of sports medicine.

[459]  G A Colditz,et al.  A prospective study of social networks in relation to total mortality and cardiovascular disease in men in the USA. , 1996, Journal of epidemiology and community health.

[460]  W. Kannel Blood pressure as a cardiovascular risk factor: prevention and treatment. , 1996, JAMA.

[461]  G. Omenn,et al.  Effects of a combination of beta carotene and vitamin A on lung cancer and cardiovascular disease. , 1996, The New England journal of medicine.

[462]  J. Manson,et al.  Lack of effect of long-term supplementation with beta carotene on the incidence of malignant neoplasms and cardiovascular disease. , 1996, The New England journal of medicine.

[463]  W C Willett,et al.  Homocysteine metabolism and risk of myocardial infarction: relation with vitamins B6, B12, and folate. , 1996, American journal of epidemiology.

[464]  B. Lernfelt,et al.  15-year longitudinal study of blood pressure and dementia , 1996, The Lancet.

[465]  F. Locatelli,et al.  Effect of the Angiotensin-Converting–Enzyme Inhibitor Benazepril on the Progression of Chronic Renal Insufficiency , 1996 .

[466]  W. Linden,et al.  Psychosocial interventions for patients with coronary artery disease: a meta-analysis. , 1996, Archives of internal medicine.

[467]  J. Hokanson,et al.  Plasma Triglyceride Level is a Risk Factor for Cardiovascular Disease Independent of High-Density Lipoprotein Cholesterol Level: A Metaanalysis of Population-Based Prospective Studies , 1996, Journal of cardiovascular risk.

[468]  W. Willett,et al.  A prospective study of folate and vitamin B6 and risk of myocardial infarction in US physicians. , 1996, Journal of the American College of Nutrition.

[469]  J Pekkanen,et al.  Body weight, cardiovascular risk factors, and coronary mortality. 15-year follow-up of middle-aged men and women in eastern Finland. , 1996, Circulation.

[470]  M. Moser,et al.  Prevention of disease progression, left ventricular hypertrophy and congestive heart failure in hypertension treatment trials. , 1996, Journal of the American College of Cardiology.

[471]  E. Rimm,et al.  Review of moderate alcohol consumption and reduced risk of coronary heart disease: is the effect due to beer, wine, or spirits? , 1996, BMJ.

[472]  H. Hein,et al.  Alcohol consumption, serum low density lipoprotein cholesterol concentration, and risk of ischaemic heart disease: six year follow up in the Copenhagen male study , 1996, BMJ.

[473]  F. Kelly,et al.  Randomised controlled trial of vitamin E in patients with coronary disease: Cambridge Heart Antioxidant Study (CHAOS) , 1996, The Lancet.

[474]  D. Phillips,et al.  Accuracy of automated finger blood pressure devices. , 1996, Family medicine.

[475]  C. Turner,et al.  A meta-analytic review of research on hostility and physical health. , 1996, Psychological bulletin.

[476]  M. Budoff,et al.  Ultrafast computed tomography as a diagnostic modality in the detection of coronary artery disease: a multicenter study. , 1996, Circulation.

[477]  I. Young,et al.  A novel single base deletion in the LDLR gene (211delG): Effect on serum lipid profiles and the influence of other genetic polymorphisms in the ACE, APOE and APOB genes. , 1996, Atherosclerosis.

[478]  Klatsky Al Alcohol, coronary disease, and hypertension , 1996 .

[479]  D. Clement A randomised, blinded, trial of Clopidogrel versus aspirin in patients at risk of ischaemic events (CAPRIE) , 1996 .

[480]  I. Rosenberg,et al.  Relation between folate status, a common mutation in methylenetetrahydrofolate reductase, and plasma homocysteine concentrations. , 1996, Circulation.

[481]  J. Siegrist Adverse health effects of high-effort/low-reward conditions. , 1996, Journal of occupational health psychology.

[482]  D. Kromhout Cholesterol, diastolic blood pressure, and stroke: 13 000 strokes in 450 000 people in 45 prospective cohorts , 1995, The Lancet.

[483]  Thomas Lee,et al.  Critical Pathways as a Strategy for Improving Care: Problems and Potential , 1995, Annals of Internal Medicine.

[484]  G. Mancia,et al.  Ambulatory blood pressure normality: results from the PAMELA study , 1995, Journal of hypertension.

[485]  J. Manson,et al.  Prospective study of shift work and risk of coronary heart disease in women. , 1995, Circulation.

[486]  Y Itzchak,et al.  Calcification of coronary arteries: detection and quantification with double-helix CT. , 1995, Radiology.

[487]  P. Macfarlane,et al.  Prevention of coronary heart disease with pravastatin in men with hypercholesterolemia , 1995 .

[488]  S. Vollset,et al.  Total plasma homocysteine and cardiovascular risk profile. The Hordaland Homocysteine Study. , 1995, JAMA.

[489]  David P Miller,et al.  Hyperhomocysteinemia and low pyridoxal phosphate. Common and independent reversible risk factors for coronary artery disease. , 1995, Circulation.

[490]  M. Flather,et al.  ACE inhibitor use in patients with myocardial infarction. Summary of evidence from clinical trials. , 1995, Circulation.

[491]  J. Cutler,et al.  Blood Pressure and Mortality Among Men With Prior Myocardial Infarction , 1995 .

[492]  J. Denollet,et al.  Personality and Mortality After Myocardial Infarction , 1995, Psychosomatic medicine.

[493]  H. Kraemer,et al.  Monounsaturated versus polyunsaturated dietary fat and serum lipids. A meta-analysis. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[494]  J. Rumberger,et al.  Coronary artery calcium area by electron-beam computed tomography and coronary atherosclerotic plaque area. A histopathologic correlative study. , 1995, Circulation.

[495]  G. Omenn,et al.  A quantitative assessment of plasma homocysteine as a risk factor for vascular disease. Probable benefits of increasing folic acid intakes. , 1995, JAMA.

[496]  V. Fuster,et al.  T2-weighted contrast for NMR characterization of human atherosclerosis. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[497]  D. Cook,et al.  Birth weight and blood pressure: cross sectional and longitudinal relations in childhood , 1995, BMJ.

[498]  J. Manson,et al.  Body weight and mortality among women. , 1995, The New England journal of medicine.

[499]  J. Jensen,et al.  Renal and systemic transvascular albumin leakage in severe atherosclerosis. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[500]  D. Arveiler,et al.  Alcohol intake modulates the effect of a polymorphism of the cholesteryl ester transfer protein gene on plasma high density lipoprotein and the risk of myocardial infarction. , 1995, The Journal of clinical investigation.

[501]  G. Lowe,et al.  Determinants of fibrin D-dimer in the Edinburgh Artery Study. , 1995, Arteriosclerosis, thrombosis, and vascular biology.

[502]  S. Kittner,et al.  Serum folate and risk for ischemic stroke. First National Health and Nutrition Examination Survey epidemiologic follow-up study. , 1995, Stroke.

[503]  D Spiegelman,et al.  Body size and fat distribution as predictors of coronary heart disease among middle-aged and older US men. , 1995, American journal of epidemiology.

[504]  J. Selhub,et al.  Homocysteine and coronary artery disease in French Canadian subjects: relation with vitamins B12, B6, pyridoxal phosphate, and folate. , 1995, The American journal of cardiology.

[505]  R. Mensink,et al.  Dietary oils, serum lipoproteins, and coronary heart disease. , 1995, The American journal of clinical nutrition.

[506]  H. Schunkert,et al.  Deletion-type allele of the angiotensin-converting enzyme gene is associated with progressive ventricular dilation after anterior myocardial infarction. Captopril and Thrombolysis Study Investigators. , 1995, Journal of the American College of Cardiology.

[507]  K. Borch-Johnsen,et al.  Microalbuminuria reflects a generalized transvascular albumin leakiness in clinically healthy subjects. , 1995, Clinical science.

[508]  J. Manson,et al.  Alcohol consumption and mortality among women. , 1995, The New England journal of medicine.

[509]  S. Yusuf,et al.  Overview of Randomized Trials of Angiotensin-Converting Enzyme Inhibitors on Mortality and Morbidity in Patients With Heart Failure , 1995 .

[510]  S. Sasaki,et al.  Dietary sodium, potassium, saturated fat, alcohol, and stroke mortality. , 1995, Stroke.

[511]  E. Araki,et al.  Intensive insulin therapy prevents the progression of diabetic microvascular complications in Japanese patients with non-insulin-dependent diabetes mellitus: a randomized prospective 6-year study. , 1995, Diabetes research and clinical practice.

[512]  N. Santanello,et al.  Cholesterol reduction yields clinical benefit. A new look at old data. , 1995, Circulation.

[513]  R S Paffenbarger,et al.  Changes in physical fitness and all-cause mortality. A prospective study of healthy and unhealthy men. , 1995, JAMA.

[514]  P. Wolf,et al.  Protective effect of fruits and vegetables on development of stroke in men. , 1995, JAMA.

[515]  P. McLennan,et al.  Dietary canola oil modifies myocardial fatty acids and inhibits cardiac arrhythmias in rats. , 1995, The Journal of nutrition.

[516]  K Poikolainen,et al.  Alcohol and mortality: a review. , 1995, Journal of clinical epidemiology.

[517]  K. Orth-Gomér Women and health. A new challenge to public health research. , 1995, Gesundheitswesen (Bundesverband der Arzte des Offentlichen Gesundheitsdienstes (Germany)).

[518]  J. Manson,et al.  Weight, weight change, and coronary heart disease in women. Risk within the 'normal' weight range. , 1995, JAMA.

[519]  D. Wood,et al.  Trans isomers of oleic and linoleic acids in adipose tissue and sudden cardiac death , 1995, The Lancet.

[520]  F. Kok,et al.  Adipose tissue isomeric trans fatty acids and risk of myocardial infarction in nine countries: the EURAMIC study , 1995, The Lancet.

[521]  R. D'Agostino,et al.  Association between plasma homocysteine concentrations and extracranial carotid-artery stenosis. , 1995, The New England journal of medicine.

[522]  K. Patrick,et al.  Physical Activity and Public Health: A Recommendation From the Centers for Disease Control and Prevention and the American College of Sports Medicine , 1995 .

[523]  M. Laakso,et al.  Hyperinsulinemic microalbuminuria. A new risk indicator for coronary heart disease. , 1995, Circulation.

[524]  J. Duffy Alcohol consumption and all-cause mortality. , 1995, International journal of epidemiology.

[525]  K. Borch-Johnsen,et al.  Atherosclerotic risk factors are increased in clinically healthy subjects with microalbuminuria. , 1995, Atherosclerosis.

[526]  E. Chew,et al.  Effects of aspirin on vitreous/preretinal hemorrhage in patients with diabetes mellitus. Early Treatment Diabetic Retinopathy Study report no. 20. , 1995, Archives of ophthalmology.

[527]  R. Matthews,et al.  A candidate genetic risk factor for vascular disease: a common mutation in methylenetetrahydrofolate reductase , 1995, Nature Genetics.

[528]  K. Yano,et al.  Body Mass Index and Thromboembolic Stroke in Nonsmoking Men in Older Middle Age: The Honolulu Heart Program , 1994, Stroke.

[529]  R. Doll,et al.  Mortality in relation to consumption of alcohol: 13 years' observations on male British doctors , 1994, BMJ.

[530]  P. Poole‐Wilson,et al.  Prevention of coronary heart disease in clinical practice. Recommendations of the Task Force of the European Society of Cardiology, European Atherosclerosis Society and European Society of Hypertension. , 1994, European heart journal.

[531]  J. Gaziano Antioxidant vitamins and coronary artery disease risk. , 1994, The American journal of medicine.

[532]  Harrington Jm,et al.  Shift work and health--a critical review of the literature on working hours , 1994 .

[533]  T. Meade Haemostatic function, arterial disease and the prevention of arterial thrombosis. , 1994, Bailliere's clinical haematology.

[534]  E. Rubin,et al.  Apolipoprotein AI transgene corrects apolipoprotein E deficiency-induced atherosclerosis in mice. , 1994, The Journal of clinical investigation.

[535]  P A Shapiro,et al.  Cardiac autonomic control and hostility in healthy subjects. , 1994, The American journal of cardiology.

[536]  R. Krauss,et al.  Coronary Artery Disease Regression: Convincing Evidence for the Benefit of Aggressive Lipoprotein Management , 1994, Circulation.

[537]  P. Touboul,et al.  Mediterranean alpha-linolenic acid-rich diet in secondary prevention of coronary heart disease , 1994, The Lancet.

[538]  J. Stengård,et al.  Antibodies to glutamic acid decarboxylase as predictors of insulin-dependent diabetes mellitus before clinical onset of disease , 1994, The Lancet.

[539]  A. G. Shaper,et al.  Alcohol and coronary heart disease: a perspective from the British Regional Heart Study. , 1994, International journal of epidemiology.

[540]  B. Magnani,et al.  Survival of myocardial infarction long-term evaluation (SMILE) study: rationale, design, organization, and outcome definitions. , 1994, Controlled clinical trials.

[541]  Gruppo Italiano per lo Studio della Soprawivenza nell'Inf Miocardico. GISSI-3: effects of lisiriopril and transdermal glyceryl trinitrate singly and together on 6-week mortality and ventricular function after acute myocardial infarction , 1994, The Lancet.

[542]  L. Berkman,et al.  Genetic susceptibility to death from coronary heart disease in a study of twins. , 1994, The New England journal of medicine.

[543]  J. Wittes,et al.  Dietary trans fatty acids: effects on plasma lipids and lipoproteins of healthy men and women. , 1994, The American journal of clinical nutrition.

[544]  J. Roseman,et al.  Plasma homocyst(e)ine, folate, and vitamin B-12 concentrations and risk for early-onset coronary artery disease. , 1994, The American journal of clinical nutrition.

[545]  T. Mackenzie,et al.  The human costs of tobacco use (1) , 1994, The New England journal of medicine.

[546]  N J Wald,et al.  By how much and how quickly does reduction in serum cholesterol concentration lower risk of ischaemic heart disease? , 1994, BMJ.

[547]  Walker,et al.  Collaborative overview of randomised trials of antiplatelet therapy Prevention of death, myocardial infarction, and stroke by prolonged antiplatelet therapy in various categories of patients , 1994 .

[548]  M. Egger,et al.  Who benefits from medical interventions? , 1994, BMJ.

[549]  R. Krauss,et al.  Low‐density lipoprotein subclass patterns and lipoprotein response to a reduced‐fat diet in men , 1994, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[550]  A. G. Shaper,et al.  Physical activity, hypertension and risk of heart attack in men without evidence of ischaemic heart disease. , 1992, Journal of human hypertension.

[551]  D. Albanes,et al.  The effect of vitamin E and beta carotene on the incidence of lung cancer and other cancers in male smokers. , 1994, The New England journal of medicine.

[552]  S. Willich,et al.  Physical exertion as a trigger of acute myocardial infarction. Triggers and Mechanisms of Myocardial Infarction Study Group. , 1993, The New England journal of medicine.

[553]  R. Goldberg,et al.  Triggering of acute myocardial infarction by heavy physical exertion. Protection against triggering by regular exertion. Determinants of Myocardial Infarction Onset Study Investigators. , 1993, The New England journal of medicine.

[554]  N. B. Myant Familial defective apolipoprotein B-100: a review, including some comparisons with familial hypercholesterolaemia. , 1993, Atherosclerosis.

[555]  J. Grimshaw,et al.  Achieving health gain through clinical guidelines. I: Developing scientifically valid guidelines. , 1993, Quality in health care : QHC.

[556]  J. Grimshaw,et al.  Effect of clinical guidelines on medical practice: a systematic review of rigorous evaluations , 1993, The Lancet.

[557]  W. Willett,et al.  Smoking Cessation in Relation to Total Mortality Rates in Women: A Prospective Cohort Study , 1993, Annals of Internal Medicine.

[558]  R. Bain,et al.  The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. , 1993 .

[559]  R. Bain,et al.  The effect of angiotensin-converting-enzyme inhibition on diabetic nephropathy. The Collaborative Study Group. , 1993, The New England journal of medicine.

[560]  E. Feskens,et al.  Dietary antioxidant flavonoids and risk of coronary heart disease: the Zutphen Elderly Study , 1993, The Lancet.

[561]  G. Murray,et al.  Effect of ramipril on mortality and morbidity of survivors of acute myocardial infarction with clinical evidence of heart failure. The Acute Infarction Ramipril Efficacy (AIRE) Study Investigators , 1993 .

[562]  G. Reaven,et al.  Insulin resistance and risk factors for coronary heart disease. , 1993, Bailliere's clinical endocrinology and metabolism.

[563]  M. Alderman,et al.  Role of Preclinical Cardiovascular Disease in the Evolution From Risk Factor Exposure to Development of Morbid Events , 1993, Circulation.

[564]  S. Genuth,et al.  The effect of intensive treatment of diabetes on the development and progression of long-term complications in insulin-dependent diabetes mellitus. , 1993, The New England journal of medicine.

[565]  B. Hedblad,et al.  Low ankle-brachial pressure index in 68-year-old men: prevalence, risk factors and prognosis. Results from prospective population study "Men born in 1914", Malmö, Sweden. , 1993, European journal of vascular surgery.

[566]  Giuseppe Mancia,et al.  1993 Guidelines for the Management of Mild Hypertension: Memorandum From a World Health Organization/ International Society of Hypertension Meeting , 1993 .

[567]  L. Kuller,et al.  Decreased ankle/arm blood pressure index and mortality in elderly women. , 1993, JAMA.

[568]  L. Kuller,et al.  Morbidity and mortality in hypertensive adults with a low ankle/arm blood pressure index. , 1993, JAMA.

[569]  David C. Atkins,et al.  Cholesterol Reduction and the Risk for Stroke in Men , 1993, Annals of Internal Medicine.

[570]  F. Song,et al.  Cholesterol lowering and mortality: the importance of considering initial level of risk. , 1993, BMJ.

[571]  J. Manson,et al.  Vitamin E consumption and the risk of coronary disease in women. , 1993, The New England journal of medicine.

[572]  E. Rimm,et al.  Vitamin E consumption and the risk of coronary heart disease in men. , 1993, The New England journal of medicine.

[573]  J. Tijssen,et al.  Retardation and arrest of progression or regression of coronary artery disease: a review. , 1993, Progress in cardiovascular diseases.

[574]  M. Lishner,et al.  Long-Term Stabilizing Effect of Angiotensin-Converting Enzyme Inhibition on Plasma Creatinine and on Proteinuria in Normotensive Type II Diabetic Patients , 1993, Annals of Internal Medicine.

[575]  F. Tüchsen Working hours and ischaemic heart disease in Danish men: a 4-year cohort study of hospitalization. , 1993, International journal of epidemiology.

[576]  G Parati,et al.  Ambulatory blood pressure monitoring use in hypertension research and clinical practice. , 1993, Hypertension.

[577]  J. Manson,et al.  Intake of trans fatty acids and risk of coronary heart disease among women , 1993, The Lancet.

[578]  R S Paffenbarger,et al.  The association of changes in physical-activity level and other lifestyle characteristics with mortality among men. , 1993, The New England journal of medicine.

[579]  K Rodahl,et al.  Physical fitness as a predictor of mortality among healthy, middle-aged Norwegian men. , 1993, The New England journal of medicine.

[580]  Y. Pawitan,et al.  Psychosocial predictors of mortality in the Cardiac Arrhythmia Suppression Trial-1 (CAST-1). , 1993, The American journal of cardiology.

[581]  J. Yudkin,et al.  Microalbuminuria: associations with height and sex in non-diabetic subjects. , 1993, BMJ.

[582]  L. Wilhelmsen,et al.  Lack of social support and incidence of coronary heart disease in middle‐aged Swedish men. , 1993, Psychosomatic medicine.

[583]  A. Folsom,et al.  Central adiposity and increased risk of coronary artery disease mortality in older women. , 1993, Annals of epidemiology.

[584]  A. Hofman,et al.  Geoffrey Rose's big idea. , 1992, BMJ.

[585]  L. Berkman,et al.  Emotional Support and Survival after Myocardial Infarction , 1992, Annals of Internal Medicine.

[586]  R. Neuwirth,et al.  Renal function change in hypertensive members of the Multiple Risk Factor Intervention Trial. Racial and treatment effects. The MRFIT Research Group. , 1992, JAMA.

[587]  J. Cruickshank β‐Blockers: Primary and Secondary Prevention , 1992 .

[588]  R. Krauss,et al.  Lipoprotein(a) in women twins: heritability and relationship to apolipoprotein(a) phenotypes. , 1992, American Journal of Human Genetics.

[589]  J. Staessen,et al.  A meta-analysis of outcome trials in elderly hypertensives. , 1992, Journal of hypertension.

[590]  E. J. Brown,et al.  Effect of captopril on mortality and morbidity in patients with left ventricular dysfunction after myocardial infarction. Results of the survival and ventricular enlargement trial. The SAVE Investigators. , 1992, The New England journal of medicine.

[591]  S. Yusuf,et al.  Effect of enalapril on mortality and the development of heart failure in asymptomatic patients with reduced left ventricular ejection fractions. , 1992, The New England journal of medicine.

[592]  K. Borch-Johnsen,et al.  Microalbuminuria: Implications for micro- and macrovascular disease , 1992, Diabetes Care.

[593]  S. Yusuf,et al.  Report of the Conference on Low Blood Cholesterol: Mortality Associations , 1992, Circulation.

[594]  A. Dattilo,et al.  Effects of weight reduction on blood lipids and lipoproteins: a meta-analysis. , 1992, The American journal of clinical nutrition.

[595]  R. Mensink,et al.  Effect of dietary fatty acids on serum lipids and lipoproteins. A meta-analysis of 27 trials. , 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

[596]  F. Mosteller,et al.  A comparison of results of meta-analyses of randomized control trials and recommendations of clinical experts. Treatments for myocardial infarction. , 1992, JAMA.

[597]  U. Ravnskov,et al.  Cholesterol lowering trials in coronary heart disease: frequency of citation and outcome. , 1992, BMJ.

[598]  D. Jacobs,et al.  Serum cholesterol level and mortality findings for men screened in the Multiple Risk Factor Intervention Trial. Multiple Risk Factor Intervention Trial Research Group. , 1992, Archives of internal medicine.

[599]  E. Boerwinkle,et al.  Apolipoprotein(a) gene accounts for greater than 90% of the variation in plasma lipoprotein(a) concentrations. , 1992, The Journal of clinical investigation.

[600]  J P Mullooly,et al.  Social networks as predictors of ischemic heart disease, cancer, stroke and hypertension: incidence, survival and mortality. , 1992, Journal of clinical epidemiology.

[601]  T. Dolecek,et al.  Epidemiological Evidence of Relationships between Dietary Polyunsaturated Fatty Acids and Mortality in the Multiple Risk Factor Intervention Trial , 1992, Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine.

[602]  P. Hopkins Effects of dietary cholesterol on serum cholesterol: a meta-analysis and review. , 1992, The American journal of clinical nutrition.

[603]  S. Schanberg,et al.  Accentuated Vagal Antagonism of β‐Adrenergic Effects on Ventricular Repolarization: Evidence of Weaker Antagonism in Hostile Type A Men , 1992, Circulation.

[604]  J. Manson,et al.  The primary prevention of myocardial infarction. , 1992, The New England journal of medicine.

[605]  G. Parati,et al.  Persistent blood pressure increase induced by heavy smoking. , 1992, Journal of hypertension.

[606]  J. Enstrom,et al.  Vitamin C Intake and Mortality among a Sample of the United States Population , 1992, Epidemiology.

[607]  T. Miettinen,et al.  Diagnosis of heterozygous familial hypercholesterolemia. DNA analysis complements clinical examination and analysis of serum lipid levels. , 1992, Arteriosclerosis and thrombosis : a journal of vascular biology.

[608]  J. Schwartz,et al.  Relation between job strain, alcohol, and ambulatory blood pressure. , 1992, Hypertension.

[609]  M. Luu,et al.  Effect of direct vasodilation with hydralazine versus angiotensin-converting enzyme inhibition with captopril on mortality in advanced heart failure: the Hy-C trial. , 1992, Journal of the American College of Cardiology.

[610]  B Meier,et al.  Relation of the site of acute myocardial infarction to the most severe coronary arterial stenosis at prior angiography. , 1992, The American journal of cardiology.

[611]  K. Alberti,et al.  Microalbuminuria and associated cardiovascular risk factors in the community. , 1992, Atherosclerosis.

[612]  R. Langer,et al.  Mortality over a period of 10 years in patients with peripheral arterial disease. , 1992, The New England journal of medicine.

[613]  M A Hlatky,et al.  Prognostic importance of social and economic resources among medically treated patients with angiographically documented coronary artery disease. , 1992, JAMA.

[614]  A. Moss,et al.  Living alone after myocardial infarction. Impact on prognosis. , 1992, JAMA.

[615]  J. Neaton,et al.  Serum cholesterol, blood pressure, cigarette smoking, and death from coronary heart disease. Overall findings and differences by age for 316,099 white men. Multiple Risk Factor Intervention Trial Research Group. , 1992, Archives of internal medicine.

[616]  J. Prochaska,et al.  In Search of How People Change: Applications to Addictive Behaviors , 1992, The American psychologist.

[617]  W. Kannel,et al.  Left ventricular hypertrophy and mortality--results from the Framingham Study. , 1992, Cardiology.

[618]  M. Marmot,et al.  Plasma cholesterol concentration and mortality. The Whitehall Study. , 1992, JAMA.

[619]  B. Dahlöf,et al.  Morbidity and mortality in the Swedish Trial in Old Patients with Hypertension (STOP-Hypertension) , 1991, The Lancet.

[620]  M. Nobuyoshi,et al.  Progression of coronary atherosclerosis: is coronary spasm related to progression? , 1991, Journal of the American College of Cardiology.

[621]  J. Salonen,et al.  Ultrasonographically assessed carotid morphology and the risk of coronary heart disease. , 1991, Arteriosclerosis and thrombosis : a journal of vascular biology.

[622]  R. D'Agostino,et al.  Relation of low diastolic blood pressure to coronary heart disease death in presence of myocardial infarction: the Framingham Study. , 1991, BMJ.

[623]  Salim Yusuf,et al.  Effect of enalapril on survival in patients with reduced left ventricular ejection fractions and congestive heart failure. , 1991, The New England journal of medicine.

[624]  F. Tristani,et al.  A comparison of enalapril with hydralazine-isosorbide dinitrate in the treatment of chronic congestive heart failure. , 1991, The New England journal of medicine.

[625]  C. F. Mendes de Leon,et al.  Change in coronary‐prone behaviors in the recurrent coronary prevention project. , 1991, Psychosomatic medicine.

[626]  W. Janowitz,et al.  Comparison of serial quantitative evaluation of calcified coronary artery plaque by ultrafast computed tomography in persons with and without obstructive coronary artery disease. , 1991, The American journal of cardiology.

[627]  Gower Street,et al.  Health inequalities among British civil servants: the Whitehall II study , 1991, The Lancet.

[628]  C. Furberg,et al.  Update of effects of calcium antagonists in myocardial infarction or angina in light of the second Danish Verapamil Infarction Trial (DAVIT-II) and other recent studies. , 1991, The American journal of cardiology.

[629]  R. D'Agostino,et al.  Dietary lipid predictors of coronary heart disease in men. The Framingham Study. , 1991, Archives of internal medicine.

[630]  L. Kuller,et al.  The ratio of ankle and arm arterial pressure as an independent predictor of mortality. , 1991, Atherosclerosis.

[631]  J. Staessen,et al.  Mean and range of the ambulatory pressure in normotensive subjects from a meta-analysis of 23 studies. , 1991, The American journal of cardiology.

[632]  M. Guazzi,et al.  Upward Shift of the Lower Range of Coronary Flow Autoregulation in Hypertensive Patients With Hypertrophy of the Left Ventricle , 1991, Circulation.

[633]  P C Elwood,et al.  Fibrinogen, Viscosity, and White Blood Cell Count Are Major Risk Factors for Ischemic Heart Disease: The Caerphilly and Speedwell Collaborative Heart Disease Studies , 1991, Circulation.

[634]  K. Anderson,et al.  An updated coronary risk profile. A statement for health professionals. , 1991, Circulation.

[635]  I. Holme,et al.  An analysis of randomized trials evaluating the effect of cholesterol reduction on total mortality and coronary heart disease incidence. , 1990, Circulation.

[636]  K. Matthews,et al.  Lowering cholesterol concentrations and mortality: Authors' reply , 1990 .

[637]  S. Haffner,et al.  Microalbuminuria. Potential marker for increased cardiovascular risk factors in nondiabetic subjects? , 1990, Arteriosclerosis.

[638]  K. Matthews,et al.  Lowering cholesterol concentrations and mortality: a quantitative review of primary prevention trials. , 1990, BMJ.

[639]  Clive Osmond,et al.  Fetal and placental size and risk of hypertension in adult life. , 1990, BMJ.

[640]  M. King,et al.  Atherogenic lipoprotein phenotype. A proposed genetic marker for coronary heart disease risk. , 1990, Circulation.

[641]  P Smith,et al.  The effect of warfarin on mortality and reinfarction after myocardial infarction. , 1990, The New England journal of medicine.

[642]  E. O’Brien,et al.  The British Hypertension Society protocol for the evaluation of automated and semi-automated blood pressure measuring devices with special reference to ambulatory systems. , 1990, Journal of hypertension.

[643]  D. Levy,et al.  Prognostic implications of echocardiographically determined left ventricular mass in the Framingham Heart Study. , 1990, The New England journal of medicine.

[644]  Robert Karasek,et al.  Healthy Work : Stress, Productivity, and the Reconstruction of Working Life , 1990 .

[645]  R. Collins,et al.  Blood pressure, stroke, and coronary heart disease Part 2, short-term reductions in blood pressure: overview of randomised drug trials in their epidemiological context , 1990, The Lancet.

[646]  V. Fuster,et al.  Regression of atherosclerotic lesions by high density lipoprotein plasma fraction in the cholesterol-fed rabbit. , 1990, The Journal of clinical investigation.

[647]  R. Collins,et al.  Blood pressure, stroke, and coronary heart disease Part 1, prolonged differences in blood pressure: prospective observational studies corrected for the regression dilution bias , 1990, The Lancet.

[648]  R. Detrano,et al.  Quantification of coronary artery calcium using ultrafast computed tomography. , 1990, Journal of the American College of Cardiology.

[649]  C. Mogensen,et al.  Microalbuminuria as predictor of increased mortality in elderly people. , 1990, BMJ.

[650]  C. Lieber,et al.  High blood alcohol levels in women. The role of decreased gastric alcohol dehydrogenase activity and first-pass metabolism. , 1990, The New England journal of medicine.

[651]  P. Elwood,et al.  EFFECTS OF CHANGES IN FAT, FISH, AND FIBRE INTAKES ON DEATH AND MYOCARDIAL REINFARCTION: DIET AND REINFARCTION TRIAL (DART) , 1989, The Lancet.

[652]  J. Buring,et al.  An overview of randomized trials of rehabilitation with exercise after myocardial infarction. , 1989, Circulation.

[653]  R B Williams,et al.  Situational determinants of cardiovascular and emotional reactivity in high and low hostile men. , 1989, Psychosomatic medicine.

[654]  A. Maseri,et al.  Coronary stenoses before and after acute myocardial infarction. , 1989, The American journal of cardiology.

[655]  T S Kristensen,et al.  Cardiovascular diseases and the work environment. A critical review of the epidemiologic literature on nonchemical factors. , 1989, Scandinavian journal of work, environment & health.

[656]  W. Browner,et al.  EfFect of Risk Status on Treatment Criteria Implications of Hypertension Trials , 1989, Hypertension.

[657]  Charles R.scriver,et al.  The Metabolic basis of inherited disease , 1989 .

[658]  F. M. Kramer,et al.  Long-term follow-up of behavioral treatment for obesity: patterns of weight regain among men and women. , 1989, International journal of obesity.

[659]  W. Kannel,et al.  Hazards of obesity--the Framingham experience. , 2009, Acta medica Scandinavica. Supplementum.

[660]  K. Orth-Gomér,et al.  Social isolation and mortality in ischemic heart disease. A 10-year follow-up study of 150 middle-aged men. , 2009, Acta medica Scandinavica.

[661]  G. Reaven Role of Insulin Resistance in Human Disease , 1988, Diabetes.

[662]  A. Maseri,et al.  Pre-existing coronary stenoses in patients with first myocardial infarction are not necessarily severe. , 1988, European heart journal.

[663]  G. Assmann,et al.  The Prospective Cardiovascular Münster (PROCAM) study: prevalence of hyperlipidemia in persons with hypertension and/or diabetes mellitus and the relationship to coronary heart disease. , 1988, American heart journal.

[664]  W. Santamore,et al.  Can coronary angiography predict the site of a subsequent myocardial infarction in patients with mild-to-moderate coronary artery disease? , 1988, Circulation.

[665]  C. Jackson,et al.  MICROALBUMINURIA AS PREDICTOR OF VASCULAR DISEASE IN NON-DIABETIC SUBJECTS Islington Diabetes Survey , 1988, The Lancet.

[666]  G. Guyatt,et al.  Cardiac rehabilitation after myocardial infarction. Combined experience of randomized clinical trials. , 1988 .

[667]  W. Willett,et al.  A prospective study of moderate alcohol consumption and the risk of coronary disease and stroke in women. , 1988, The New England journal of medicine.

[668]  S. Syme,et al.  Social connections and mortality from all causes and from cardiovascular disease: prospective evidence from eastern Finland. , 1988, American journal of epidemiology.

[669]  Jeremiah Stamler,et al.  Intersalt: an international study of electrolyte excretion and blood pressure. Results for 24 hour urinary sodium and potassium excretion. Intersalt Cooperative Research Group. , 1988 .

[670]  V. Fuster,et al.  Angiographic progression of coronary artery disease and the development of myocardial infarction. , 1988, Journal of the American College of Cardiology.

[671]  P. Wilson,et al.  High Density Lipoprotein Cholesterol, Total Cholesterol Screening, and Myocardial Infarction: The Framingham Study , 1988, Arteriosclerosis.

[672]  J. Laragh,et al.  How common is white coat hypertension? , 1988, JAMA.

[673]  G. Reaven,et al.  Additive Hypoglycemic Effects of Drugs That Modify Free-Fatty Acid Metabolism by Different Mechanisms in Rats With Streptozocin-Induced Diabetes , 1988, Diabetes.

[674]  L. Wilhelmsen Coronary heart disease: epidemiology of smoking and intervention studies of smoking. , 1988, American heart journal.

[675]  J. Huttunen,et al.  Helsinki Heart Study: primary-prevention trial with gemfibrozil in middle-aged men with dyslipidemia. Safety of treatment, changes in risk factors, and incidence of coronary heart disease. , 1987, The New England journal of medicine.

[676]  M. B. Katan,et al.  Total Cholesterol and High Density Lipoprotein Cholesterol Levels in Populations Differing in Fat and Carbohydrate Intake , 1987, Arteriosclerosis.

[677]  P. Elwood,et al.  Some long term effects of smoking on the haemostatic system: a report from the Caerphilly and Speedwell Collaborative Surveys. , 1987, Journal of clinical pathology.

[678]  S. Syme,et al.  Social networks and coronary artery disease: a comparison of the structure and function of social relations as predictors of disease. , 1987, Psychosomatic medicine.

[679]  S. Kreiner,et al.  Proteinuria: value as predictor of cardiovascular mortality in insulin dependent diabetes mellitus. , 1987, British medical journal.

[680]  L. Rand,et al.  Magnitude and determinants of coronary artery disease in juvenile-onset, insulin-dependent diabetes mellitus. , 1987, The American journal of cardiology.

[681]  M. Laakso,et al.  Diabetes and atherosclerosis: an epidemiologic view. , 1987, Diabetes/metabolism reviews.

[682]  J. Cruickshank,et al.  BENEFITS AND POTENTIAL HARM OF LOWERING HIGH BLOOD PRESSURE , 1987, The Lancet.

[683]  M. Katan,et al.  Characteristics of human hypo- and hyperresponders to dietary cholesterol. , 1987, American journal of epidemiology.

[684]  G Parati,et al.  Alerting reaction and rise in blood pressure during measurement by physician and nurse. , 1987, Hypertension.

[685]  T S Warrender,et al.  Randomised trial of treatment of hypertension in elderly patients in primary care. , 1986, British medical journal.

[686]  J. Salonen,et al.  Decline in cardiovascular mortality in North Karelia and other parts of Finland. , 1986, British medical journal.

[687]  J. J. Gill,et al.  Alteration of type A behavior and its effect on cardiac recurrences in post myocardial infarction patients: summary results of the recurrent coronary prevention project. , 1986, American heart journal.

[688]  S. Thompson,et al.  HAEMOSTATIC FUNCTION AND ISCHAEMIC HEART DISEASE: PRINCIPAL RESULTS OF THE NORTHWICK PARK HEART STUDY , 1986, The Lancet.

[689]  J. Laragh,et al.  Value of echocardiographic measurement of left ventricular mass in predicting cardiovascular morbid events in hypertensive men. , 1986, Annals of internal medicine.

[690]  T. Åkerstedt,et al.  INCREASED RISK OF ISCHAEMIC HEART DISEASE IN SHIFT WORKERS , 1986, The Lancet.

[691]  M. Katan,et al.  Existence of consistent hypo- and hyperresponders to dietary cholesterol in man. , 1986, American journal of epidemiology.

[692]  H. Kesteloot,et al.  Serum Lipids in the People's Republic of China: Comparison of Western and Eastern Populations , 1985, Arteriosclerosis.

[693]  C. Bulpitt,et al.  Mortality and Morbidity Results from the European Working Party on High Blood Pressure in the Elderly Trial , 1985, The Lancet.

[694]  R. Peto,et al.  Beta blockade during and after myocardial infarction: an overview of the randomized trials. , 1985, Progress in cardiovascular diseases.

[695]  E. Barrett-Connor,et al.  TABLE 1 Prevalence of PAD by traditional assessment : intermittent claudication and pulse palpation % Claudication % Pulse abnormalities Rose Femoral Posterior Dorsalis n Rose , 2005 .

[696]  S. Thompson,et al.  Epidemiological characteristics of platelet aggregability. , 1985, British medical journal.

[697]  M. Bourassa,et al.  Clinical and angiographic predictors of new total coronary occlusion in coronary artery disease: analysis of 313 nonoperated patients. , 1984, The American journal of cardiology.

[698]  K. Pennert,et al.  Distribution of adipose tissue and risk of cardiovascular disease and death: a 12 year follow up of participants in the population study of women in Gothenburg, Sweden. , 1984, British medical journal.

[699]  J. Goldberg,et al.  Psychosocial influences on mortality after myocardial infarction. , 1984, The New England journal of medicine.

[700]  P. Björntorp,et al.  Abdominal adipose tissue distribution, obesity, and risk of cardiovascular disease and death: 13 year follow up of participants in the study of men born in 1913. , 1984, British medical journal.

[701]  G. Viberti,et al.  Microalbuminuria Predicts Mortality in Noninsulin‐dependent Diabetes , 1984, Diabetic medicine : a journal of the British Diabetic Association.

[702]  C. Mogensen,et al.  Microalbuminuria predicts clinical proteinuria and early mortality in maturity-onset diabetes. , 1984, The New England journal of medicine.

[703]  Giuseppe Mancia,et al.  EFFECTS OF BLOOD-PRESSURE MEASUREMENT BY THE DOCTOR ON PATIENT'S BLOOD PRESSURE AND HEART RATE , 1983, The Lancet.

[704]  A. Hofman,et al.  A randomized trial of sodium intake and blood pressure in newborn infants. , 1983, JAMA.

[705]  A Pedotti,et al.  Blood Pressure and Heart Rate Variabilities in Normotensive and Hypertensive Human Beings , 1983, Circulation research.

[706]  A. Ostfeld,et al.  Hostility, Risk of Coronary Heart Disease, and Mortality , 1983, Psychosomatic medicine.

[707]  Daniel L. McGee,et al.  Social networks and coronary heart disease among Japanese men in Hawaii. , 1983, American journal of epidemiology.

[708]  R. Williams,et al.  Hostility, CHD incidence, and total mortality: a 25-year follow-up study of 255 physicians. , 1983, Psychosomatic medicine.

[709]  C E Metz,et al.  Critical evaluation of stress testing in the diagnosis of peripheral vascular disease. , 1982, Surgery.

[710]  G. Rose,et al.  Strategy of prevention: lessons from cardiovascular disease. , 1981, British medical journal.

[711]  M. Sporn,et al.  Can dietary beta-carotene materially reduce human cancer rates? , 1981, Nature.

[712]  P. Puska,et al.  A community-based intervention study on the feasibility and effects of the reduction of salt intake in North Karelia, Finland. , 1981, Acta cardiologica.

[713]  R. Whalen,et al.  Type A Behavior, Hostility, and Coronary Atherosclerosis* , 1980, Psychosomatic medicine.

[714]  A. Bruschke,et al.  Clinical Course of Patients with Normal or Slightly or Moderately Abnormal Coronary Arteriograms: 10‐year Follow‐up of 521 Patients , 1980, Circulation.

[715]  R. Bawol,et al.  Epidemiology as a guide to clinical decisions. The association between triglyceride and coronary heart disease. , 1980, The New England journal of medicine.

[716]  A. Vedin,et al.  Influence of a myocardial infarction on blood pressure and serum cholesterol. , 2009, Acta medica Scandinavica.

[717]  L. Wilhelmsen Salt and hypertension. , 1979, Clinical science.

[718]  R. Rifkin,et al.  Coronary calcification in the diagnosis of coronary artery disease. , 1979, The American journal of cardiology.

[719]  A. Forsdahl,et al.  Are poor living conditions in childhood and adolescence an important risk factor for arteriosclerotic heart disease? , 1977, International journal of rehabilitation research. Internationale Zeitschrift fur Rehabilitationsforschung. Revue internationale de recherches de readaptation.

[720]  D. Grafnetter,et al.  A co-operative trial in the primary prevention of ischaemic heart disease using clofibrate. Report from the Committee of Principal Investigators. , 1978, British heart journal.

[721]  A. Motulsky,et al.  Hyperlipidemia in coronary heart disease. I. Lipid levels in 500 survivors of myocardial infarction. , 1973, The Journal of clinical investigation.

[722]  H. Kato,et al.  Epidemiologic studies of coronary heart disease and stroke in Japanese men living in Japan, Hawaii and California. , 1973, American journal of epidemiology.

[723]  R. Levy,et al.  Estimation of the concentration of low-density lipoprotein cholesterol in plasma, without use of the preparative ultracentrifuge. , 1972, Clinical chemistry.

[724]  D. Patterson,et al.  Lipid abnormalities in male and female survivors of myocardial infarction and their first-degree relatives. , 1972, Lancet.

[725]  G. Borg Perceived exertion as an indicator of somatic stress. , 2019, Scandinavian journal of rehabilitation medicine.

[726]  J. Hobbs,et al.  Ankle systolic pressure measurements in arterial disease affecting the lower extremities , 1969, The British journal of surgery.

[727]  E. C. Hammond,et al.  Coronary heart disease, roke, and aortic aneurysm. Factors in the etiology. , 1969, Archives of environmental health.

[728]  K. Mccully Vascular pathology of homocysteinemia: implications for the pathogenesis of arteriosclerosis. , 1969, The American journal of pathology.

[729]  F. R. Zadik FRACTURE OF THE FEMORAL NECK. , 1964, Lancet.

[730]  David H. Blankenhorn,et al.  CORONARY ARTERIAL CALCIFICATION A REVIEW , 1961 .