Genome-wide meta-analysis identifies 11 new loci for anthropometric traits and provides insights into genetic architecture
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Christian Gieger | Jianxin Shi | Inês Barroso | Andres Metspalu | Mark I. McCarthy | Karen L. Mohlke | Philippe Froguel | Dorret I. Boomsma | Meena Kumari | Sarah E. Medland | Alexander Teumer | Karl-Heinz Jöckel | Markus Perola | Nicole Soranzo | Zoltán Kutalik | Dan-Yu Lin | Frank Kee | Niina Eklund | Eric Boerwinkle | Sang Hong Lee | Peter M. Visscher | Vilmundur Gudnason | Vincent Mooser | Igor Rudan | Kari Stefansson | Lars Lind | Kari Kuulasmaa | Jing Hua Zhao | Paul W. Franks | Diana Marek | David Meyre | Martina Müller-Nurasyid | Fredrik Karpe | Yudi Pawitan | Harald Grallert | Lenore J. Launer | Ingrid B. Borecki | Michael A. Province | Alan R. Sanders | Douglas F. Levinson | Stephen J. Chanock | Nicholas G. Martin | Anne U. Jackson | Sarah Edkins | Johanna Kuusisto | Peter P. Pramstaller | Jennifer E. Huffman | Jeffrey R. O’Connell | Goncalo R. Abecasis | Benjamin M. Neale | Paul M. Ridker | Harry Campbell | Lude Franke | Reedik Mägi | Eric E. Schadt | David Schlessinger | Peter S. Chines | Cristen J. Willer | Michael Stumvoll | Andrew D. Morris | Paolo Brambilla | Cecilia M. Lindgren | Andrea Ganna | Fernando Rivadeneira | Claes Ohlsson | Ronald P. Stolk | John F. Peden | Rona J. Strawbridge | Sarah E. Hunt | Nilesh J. Samani | Juha Sinisalo | Ulf Gyllensten | Patricia B. Munroe | Barbara Thorand | Mark J. Caulfield | Jian Yang | Mary F. Feitosa | Per Hall | Yi-Juan Hu | Caroline Hayward | Michael Boehnke | Valgerdur Steinthorsdottir | Alena Stančáková | Gudmar Thorleifsson | Philippe Amouyel | Panos Deloukas | Jean Ferrières | Sekar Kathiresan | Claudia Langenberg | Erik Ingelsson | Rainer Rauramaa | Nicholas J. Wareham | Anuj Goel | Tamara B. Harris | Stefan Gustafsson | Henrik Grönberg | Thomas W. Winkler | Sonja I. Berndt | Tõnu Esko | Tsegaselassie Workalemahu | Felix R. Day | Tove Fall | Sailaja Vedantam | Andrew R. Wood | Josine L. Min | George Nicholson | Inga Prokopenko | Lindsay L. Waite | Aldi T. Kraja | L. Adrienne Cupples | Samuli Ripatti | Ida Surakka | Francis S. Collins | Jeanette Erdmann | Heribert Schunkert | Carolina Medina-Gomez | Karol Estrada | M. Carola Zillikens | Alistair S. Hall | Lyle J. Palmer | Marja-Liisa Lokki | Mattias Lorentzon | Johan G. Eriksson | Ilja M. Nolte | Harold Snieder | Pablo V. Gejman | Kevin B. Jacobs | Daniel I. Chasman | Lynda M. Rose | Carlos Iribarren | Hanneke Basart | Elina Hyppönen | Timo A. Lakka | Timo E. Saaristo | Elena Tremoli | Marcus E. Kleber | Diana Kuh | Maria Dimitriou | Kathleen Stirrups | Aroon Hingorani | Themistocles L. Assimes | Caroline S. Fox | Timothy Frayling | Leif C. Groop | David P. Strachan | Iris M. Heid | Albert Hofman | Lu Qi | Cornelia M. van Duijn | Paolo Manunta | Anke Tönjes | Klaus Stark | Joshua C. Randall | Michael Preuss | Veikko Salomaa | Stefan Schreiber | Grant W. Montgomery | Andrew P. Morris | Christian Hengstenberg | Annette Peters | Thomas Illig | Aarno Palotie | Folkert W. Asselbergs | Anne E. Justice | Daniele Cusi | Gérard Waeber | Andrew A. Hicks | Lori L. Bonnycastle | Terho Lehtimäki | André G. Uitterlinden | Augusto Rendon | Massimo Mangino | Mika Kähönen | André Scherag | Johannes Hebebrand | Martin Farrall | Winfried März | Kari E. North | Liming Liang | Gonneke Willemsen | Mariano Dei | Nancy L. Heard-Costa | Alan F. Wright | Andrew C. Heath | Serena Sanna | Bernhard O. Boehm | Jouke-Jan Hottenga | Stavroula Kanoni | Ben A. Oostra | Jorma Viikari | Inke R. König | Claudia Lamina | Mika Kivimaki | Barbara McKnight | Jaakko Tuomilehto | Kristian Hveem | Frank B. Hu | Kay-Tee Khaw | Ozren Polasek | Jennifer L. Bragg-Gresham | Joel N. Hirschhorn | Thomas W. Mühleisen | Lili Milani | Unnur Thorsteinsdottir | Bruce M. Psaty | Markku S. Nieminen | Anders Hamsten | Pim van der Harst | Krista Fischer | Ken K. Ong | Veronique Vitart | Julius S. Ngwa | Mustafa Atalay | So-Youn Shin | Eleanor Wheeler | Willem H. Ouwehand | Wolfgang Koenig | Aparna Radhakrishnan | Sabine Schipf | Marjolein J. Peters | Anneli Pouta | Najaf Amin | Ulf de Faire | Nancy Pedersen | Georg Homuth | Peter Vollenweider | David Hunter | Martin den Heijer | John Beilby | Anna-Liisa Hartikainen | Lavinia Paternoster | Davide Gentilini | Robert C. Kaplan | Marjo-Riitta Jarvelin | David M. Evans | Jianjun Liu | M. Jarvelin | M. Peters | L. Liang | C. Gieger | P. Visscher | A. Hofman | A. Uitterlinden | D. Absher | T. Assimes | T. Spector | J. V. van Meurs | A. Peters | R. Mägi | E. Mihailov | M. McCarthy | P. Deloukas | A. Morris | D. Strachan | F. Hu | G. Abecasis | K. Kristiansson | K. Stirrups | T. Lehtimäki | T. Mühleisen | L. Kiemeney | U. Thorsteinsdóttir | K. Stefánsson | S. Hunt | E. Boerwinkle | V. Salomaa | M. Perola | Jianxin Shi | C. Lindgren | J. Hirschhorn | L. Groop | M. Laakso | D. Schlessinger | J. O’Connell | F. Collins | Z. Kutalik | M. Boehnke | I. König | B. Neale | P. Ridker | D. Chasman | W. Ouwehand | N. Samani | A. Attwood | W. McArdle | A. Balmforth | A. Hall | M. Mangino | J. Connell | P. Munroe | M. Caulfield | M. Farrall | T. Frayling | T. Ferreira | V. Gudnason | E. Schadt | J. Viikari | P. Hall | Y. Pawitan | H. Grönberg | I. Borecki | Albert Vernon Smith | M. Nieminen | S. Edkins | S. Chanock | D. Hunter | A. Hingorani | D. Lin | N. Martin | W. Cookson | O. Raitakari | F. Rivadeneira | J. Witteman | C. Fox | G. Thorleifsson | V. Steinthorsdottir | J. Beilby | L. Palmer | A. Rendon | J. Erdmann | C. Hengstenberg | H. Wichmann | D. Tregouet | H. Schunkert | B. Psaty | S. Wild | S. Schreiber | B. Penninx | G. Willemsen | A. Kraja | M. Province | J. Peden | A. Palotie | S. Ripatti | A. Metspalu | T. Esko | G. Montgomery | H. Snieder | L. Milani | K. Fischer | E. Ingelsson | Michael H. Preuss | K. Stark | K. Jacobs | Zhaoming Wang | K. Mohlke | L. Bonnycastle | C. Willer | P. Chines | A. Jackson | A. Swift | N. Narisu | J. Saramies | J. Tuomilehto | A. Morris | S. Kathiresan | E. Speliotes | J. Virtamo | D. Meyre | P. Froguel | T. Illig | L. Lind | I. Heid | W. März | T. Harris | T. Lakka | R. Rauramaa | I. Rudan | D. Boomsma | M. Stumvoll | N. Eklund | D. Levinson | K. Jöckel | P. Amouyel | S. Berndt | N. Wareham | Jianjun Liu | I. Surakka | J. Hottenga | S. Gustafsson | H. Grallert | A. Hamsten | E. Hyppönen | P. Magnusson | M. Müller-Nurasyid | N. Pedersen | C. V. van Duijn | J. Eriksson | A. Jula | C. Power | L. Franke | I. Prokopenko | P. Franks | V. Mooser | J. Lindström | M. Uusitupa | L. Cupples | U. de Faire | A. Heath | N. Soranzo | G. Homuth | A. Teumer | S. Medland | J. Tyrer | K. North | A. Wright | W. Koenig | K. Estrada | H. Watkins | B. Boehm | M. Moffatt | B. Oostra | B. Wolffenbuttel | L. Waite | K. Ong | J. Hebebrand | A. Hinney | I. Njølstad | I. Barroso | J. Sambrook | J. Stephens | D. Evans | T. Johnson | Jian Yang | E. Albrecht | N. Amin | C. Hayward | S. Kanoni | S. Lee | O. Polašek | V. Vitart | H. Campbell | G. Dedoussis | M. Dimitriou | M. Kähönen | L. Launer | P. Madden | P. Vollenweider | G. Waeber | E. Widén | James F. Wilson | M. Feitosa | T. Winkler | A. Goel | J. Luan | I. Nolte | A. Stančáková | J. Kuusisto | C. Langenberg | L. Rose | A. Oldehinkel | P. van der Harst | C. Ohlsson | S. Sanna | T. Sørensen | R. Loos | R. Strawbridge | S. Pechlivanis | S. Vedantam | A. Wood | M. Atalay | B. Thorand | M. Trip | C. Palmer | L. Qi | K. Hovingh | K. Khaw | S. Keinanen-Kiukaanniemi | T. Saaristo | K. Hveem | E. Tremoli | A. Ganna | J. Bragg-Gresham | Å. Johansson | M. Kleber | D. Shungin | A. Wong | P. Brambilla | A. Hartikainen | A. Hicks | M. Kumari | A. Pouta | J. Zhao | J. Ferrières | U. Gyllensten | C. Iribarren | M. Kivimaki | D. Kuh | P. Pramstaller | T. Fall | Guo Li | G. Navis | F. Day | S. Vermeulen | M. den Heijer | K. Kuulasmaa | J. Min | So-Youn Shin | S. Schipf | H. Wallaschofski | E. Wheeler | N. Heard-Costa | J. Randall | T. Workalemahu | M. Zillikens | K. Monda | M. Lorentzon | B. McKnight | J. Ngwa | L. Vandenput | J. Laitinen | M. Lokki | A. Sanders | J. Sinisalo | D. Cusi | P. Gejman | A. Musk | A. Tönjes | R. Kaplan | D. Croteau-Chonka | A. Scherag | A. Justice | C. Medina-Gomez | J. V. van Vliet-Ostaptchouk | M. Bruinenberg | F. Kee | P. Manunta | R. Stolk | F. Asselbergs | M. Ferrario | F. Karpe | C. Lamina | J. Jansson | I. Jarick | C. Lecoeur | D. Marek | G. Nicholson | M. M. van der Klauw | I. Mateo Leach | H. Basart | B. Winkelmann | Yijuan Hu | Mariano Dei | F. Frau | J. Huffman | A. Liuzzi | G. Cadby | L. Paternoster | E. Nøhr | S. Signorini | A. Radhakrishnan | D. Gentilini | F. de Vegt | A. D. di Blasio | Zhaoming Wang | Jarmo Virtamo | Devin Absher | Narisu Narisu | Markku Laakso | Inger Njølstad | Åsa Johansson | Timothy D. Spector | Matti Uusitupa | Henri Wallaschofski | H.-Erich Wichmann | Sarah H. Wild | Teresa Ferreira | Evelin Mihailov | Antti Jula | Chris Power | Mieke D. Trip | Toby Johnson | Hugh Watkins | Eva Albrecht | Cecile Lecoeur | Jaana Lindström | Jonathan Tyrer | Olli Raitakari | Gerjan Navis | Jennifer G. Sambrook | John-Olov Jansson | Liesbeth Vandenput | Jouko Saramies | Andrew Wong | Ivonne Jarick | Anke Hinney | Irene Mateo Leach | Bernhard R. Winkelmann | Lambertus A. Kiemeney | C. Pütter | B. Skrobek | E. Theodoraki | Talin Haritunian | Keri L. Monda | Brenda Penninx | Jacqueline C.M. Witteman | Gemma Cadby | Colin N.A. Palmer | Anthony J. Balmforth | Carolin Pütter | Guo Li | Stefano Signorini | Anna Maria Di Blasio | Jian’an Luan | Kati Kristiansson | Ruth J.F. Loos | Elizabeth K. Speliotes | Wendy L. McArdle | Amy J. Swift | Pamela A. Madden | Elisabeth Widén | David-Alexandre Tregouet | Sita H. Vermeulen | Miriam Moffatt | Michael H Preuss | Dmitry Shungin | Arthur W. Musk | George V. Dedoussis | Marcel Bruinenberg | William Cookson | Francesca Frau | Antonio Liuzzi | Albertine J. Oldehinkel | Patrik K. Magnusson | Thorkild I.A. 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[1] Elsi,et al. Biobanking and Biomolecular Resources Research Infrastructure , 2015 .
[2] U. Ekelund,et al. Evaluation of common genetic variants identified by GWAS for early onset and morbid obesity in population-based samples , 2013, International Journal of Obesity.
[3] M. Rieder,et al. Exome sequencing of extreme phenotypes identifies DCTN4 as a modifier of chronic Pseudomonas aeruginosa infection in cystic fibrosis , 2012, Nature Genetics.
[4] P. Visscher,et al. A Better Coefficient of Determination for Genetic Profile Analysis , 2012, Genetic epidemiology.
[5] P. Visscher,et al. Conditional and joint multiple-SNP analysis of GWAS summary statistics identifies additional variants influencing complex traits , 2012, Nature Genetics.
[6] Inês Barroso,et al. A genome-wide association meta-analysis identifies new childhood obesity loci , 2012, Nature Genetics.
[7] Yusuke Nakamura,et al. Common variants at CDKAL1 and KLF9 are associated with body mass index in east Asian populations , 2012, Nature Genetics.
[8] Gary K. Chen,et al. Meta-analysis identifies common variants associated with body mass index in East Asians , 2012, Nature Genetics.
[9] Quin F. Wills,et al. Coexpression Network Analysis in Abdominal and Gluteal Adipose Tissue Reveals Regulatory Genetic Loci for Metabolic Syndrome and Related Phenotypes , 2012, PLoS genetics.
[10] E. Lander,et al. The mystery of missing heritability: Genetic interactions create phantom heritability , 2012, Proceedings of the National Academy of Sciences.
[11] Paul T. Williams. Quantile-Specific Penetrance of Genes Affecting Lipoproteins, Adiposity and Height , 2012, PloS one.
[12] Wei Lu,et al. Meta-analysis of genome-wide association studies identifies eight new loci for type 2 diabetes in east Asians , 2011, Nature Genetics.
[13] C. Gieger,et al. Eight genetic loci associated with variation in lipoprotein-associated phospholipase A2 mass and activity and coronary heart disease: meta-analysis of genome-wide association studies from five community-based studies. , 2012, European heart journal.
[14] Markus Perola,et al. Common Variants Show Predicted Polygenic Effects on Height in the Tails of the Distribution, Except in Extremely Short Individuals , 2011, PLoS genetics.
[15] M. Nöthen,et al. Missing Heritability in the Tails of Quantitative Traits? A Simulation Study on the Impact of Slightly Altered True Genetic Models , 2011, Human Heredity.
[16] Taesung Park,et al. Large-scale genome-wide association studies in east Asians identify new genetic loci influencing metabolic traits , 2011, Nature Genetics.
[17] Anders D. Børglum,et al. Genome-wide association study identifies five new schizophrenia loci , 2011, Nature Genetics.
[18] Manuel A. R. Ferreira,et al. Genetic variants in LPL, OASL and TOMM40/APOE-C1-C2-C4 genes are associated with multiple cardiovascular-related traits , 2011, BMC Medical Genetics.
[19] Torben Hansen,et al. Genome-Wide Population-Based Association Study of Extremely Overweight Young Adults – The GOYA Study , 2011, PloS one.
[20] Sarah E. Medland,et al. A Quantitative-Trait Genome-Wide Association Study of Alcoholism Risk in the Community: Findings and Implications , 2011, Biological Psychiatry.
[21] Christian Gieger,et al. Genetic Variants in Novel Pathways Influence Blood Pressure and Cardiovascular Disease Risk , 2011, Nature.
[22] John A. Todd,et al. Genome-Wide Association Analysis of Autoantibody Positivity in Type 1 Diabetes Cases , 2011, PLoS genetics.
[23] Ryan D. Hernandez,et al. Meta-analysis of Genome-wide Association Studies of Asthma In Ethnically Diverse North American Populations , 2011, Nature Genetics.
[24] N. Mehta. Large-scale association analysis identifies 13 new susceptibility loci for coronary artery disease. , 2011, Circulation. Cardiovascular genetics.
[25] Yusuke Nakamura,et al. Identification of Nine Novel Loci Associated with White Blood Cell Subtypes in a Japanese Population , 2011, PLoS genetics.
[26] F. Gianfrancesco,et al. Genome-wide association identifies three new susceptibility loci for Paget's disease of bone , 2011, Nature Genetics.
[27] D. Altshuler,et al. Power in the phenotypic extremes: a simulation study of power in discovery and replication of rare variants , 2011, Genetic epidemiology.
[28] F. Tsai,et al. Genome-wide association study of diabetic retinopathy in a Taiwanese population. , 2011, Ophthalmology.
[29] Nilesh J Samani,et al. Dense Genotyping of Candidate Gene Loci Identifies Variants Associated With High-Density Lipoprotein Cholesterol , 2011, Circulation. Cardiovascular genetics.
[30] Steve D. M. Brown,et al. Genome-Wide Association Study Using Extreme Truncate Selection Identifies Novel Genes Affecting Bone Mineral Density and Fracture Risk , 2011, PLoS genetics.
[31] Manuel A. R. Ferreira,et al. Association between ORMDL3, IL1RL1 and a deletion on chromosome 17q21 with asthma risk in Australia , 2011, European Journal of Human Genetics.
[32] P. Visscher,et al. Estimating missing heritability for disease from genome-wide association studies. , 2011, American journal of human genetics.
[33] Ian J. Deary,et al. Whole genome association scan for genetic polymorphisms influencing information processing speed , 2011, Biological Psychology.
[34] Nine V.A.M. Knoers,et al. Mutations in the Pre-Replication Complex cause Meier-Gorlin syndrome , 2011, Nature Genetics.
[35] Tariq Ahmad,et al. Meta-analysis identifies 29 additional ulcerative colitis risk loci, increasing the number of confirmed associations to 47 , 2011, Nature Genetics.
[36] B. Sander,et al. High‐resolution genomic screening in mantle cell lymphoma—specific changes correlate with genomic complexity, the proliferation signature and survival , 2011, Genes, chromosomes & cancer.
[37] M. Bayés,et al. Association study of six candidate genes asymmetrically expressed in the two cerebral hemispheres suggests the involvement of BAIAP2 in autism. , 2011, Journal of psychiatric research.
[38] Mark I. McCarthy,et al. A genome-wide association study in Europeans and South Asians identifies five new loci for coronary artery disease , 2011, Nature Genetics.
[39] Donald W. Bowden,et al. Genome-Wide Association Study of Coronary Heart Disease and Its Risk Factors in 8,090 African Americans: The NHLBI CARe Project , 2011, PLoS genetics.
[40] M. Goodell,et al. Genome-wide association study of recurrent early-onset major depressive disorder , 2010, Molecular Psychiatry.
[41] A. Hata,et al. A genome-wide association study identifies RNF213 as the first Moyamoya disease gene , 2011, Journal of Human Genetics.
[42] T. Hansen,et al. Genome wide association study identifies KCNMA1 contributing to human obesity , 2011, BMC Medical Genomics.
[43] Allissa Dillman,et al. Genome-wide screen identifies rs646776 near sortilin as a regulator of progranulin levels in human plasma. , 2010, American journal of human genetics.
[44] Vineet Bafna,et al. Population sequencing of two endocannabinoid metabolic genes identifies rare and common regulatory variants associated with extreme obesity and metabolite level , 2010, Genome Biology.
[45] R. Hui,et al. Mutations in NEXN, a Z-disc gene, are associated with hypertrophic cardiomyopathy. , 2010, American journal of human genetics.
[46] H. Aburatani,et al. Proteomic Analysis of Native Hepatocyte Nuclear Factor-4α (HNF4α) Isoforms, Phosphorylation Status, and Interactive Cofactors* , 2010, The Journal of Biological Chemistry.
[47] Thomas Meitinger,et al. Meta-analysis identifies 13 new loci associated with waist-hip ratio and reveals sexual dimorphism in the genetic basis of fat distribution , 2010, Nature Genetics.
[48] Inês Barroso,et al. Genetic Variants Influencing Circulating Lipid Levels and Risk of Coronary Artery Disease , 2010, Arteriosclerosis, thrombosis, and vascular biology.
[49] Florence Demenais,et al. A large-scale, consortium-based genomewide association study of asthma. , 2010, The New England journal of medicine.
[50] P. Madsen,et al. Sort1, encoded by the cardiovascular risk locus 1p13.3, is a regulator of hepatic lipoprotein export. , 2010, Cell metabolism.
[51] G. Fain,et al. Replacing the rod with the cone transducin α subunit decreases sensitivity and accelerates response decay , 2010, The Journal of physiology.
[52] A. Yashin,et al. Joint influence of small-effect genetic variants on human longevity , 2010, Aging.
[53] Ayellet V. Segrè,et al. Hundreds of variants clustered in genomic loci and biological pathways affect human height , 2010, Nature.
[54] D. Balding,et al. A Genome-Wide Association Study of the Metabolic Syndrome in Indian Asian Men , 2010, PloS one.
[55] Fabio Macciardi,et al. Genome-wide meta-analyses identify three loci associated with primary biliary cirrhosis , 2010, Nature Genetics.
[56] N. Martin,et al. A Genome-Wide Association Study of Self-Rated Health , 2010, Twin Research and Human Genetics.
[57] Tanya M. Teslovich,et al. Biological, Clinical, and Population Relevance of 95 Loci for Blood Lipids , 2010, Nature.
[58] Yun Li,et al. METAL: fast and efficient meta-analysis of genomewide association scans , 2010, Bioinform..
[59] H. Hakonarson,et al. ANNOVAR: functional annotation of genetic variants from high-throughput sequencing data , 2010, Nucleic acids research.
[60] Jeroen A. A. Demmers,et al. ATAC and Mediator coactivators form a stable complex and regulate a set of non‐coding RNA genes , 2010, EMBO reports.
[61] Nicolas Levy,et al. CAMOS, a nonprogressive, autosomal recessive, congenital cerebellar ataxia, is caused by a mutant zinc-finger protein, ZNF592 , 2010, European Journal of Human Genetics.
[62] Michael R. Johnson,et al. Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study , 2010, Brain : a journal of neurology.
[63] Jing Cui,et al. Genome-wide association study meta-analysis identifies seven new rheumatoid arthritis risk loci , 2010, Nature Genetics.
[64] A. Hofman,et al. A Genome-Wide Association Study of Optic Disc Parameters , 2010, PLoS genetics.
[65] Jo Lambert,et al. Variant of TYR and autoimmunity susceptibility loci in generalized vitiligo. , 2010, The New England journal of medicine.
[66] Uwe Völker,et al. New loci associated with kidney function and chronic kidney disease , 2010, Nature Genetics.
[67] Xia Yang,et al. Integrating pathway analysis and genetics of gene expression for genome-wide association studies. , 2010, American journal of human genetics.
[68] Kathryn Roeder,et al. Genome-wide association identifies multiple ulcerative colitis susceptibility loci , 2010, Nature Genetics.
[69] Raimund Erbel,et al. Two New Loci for Body-Weight Regulation Identified in a Joint Analysis of Genome-Wide Association Studies for Early-Onset Extreme Obesity in French and German Study Groups , 2010, PLoS genetics.
[70] Paul T. Williams,et al. Genome-Wide Association of Lipid-Lowering Response to Statins in Combined Study Populations , 2010, PloS one.
[71] William D Fraser,et al. Genome wide association study identifies variants at CSF1, OPTN and TNFRSF11A as genetic risk factors for Paget’s disease of bone , 2010, Nature Genetics.
[72] Alex Doney,et al. Genetic variation in GIPR influences the glucose and insulin responses to an oral glucose challenge , 2010, Nature Genetics.
[73] Christian Gieger,et al. New genetic loci implicated in fasting glucose homeostasis and their impact on type 2 diabetes risk , 2010, Nature Genetics.
[74] J. Mandl,et al. Hexose-6-phosphate dehydrogenase in the endoplasmic reticulum , 2010, Biological chemistry.
[75] B. Han,et al. Identification of 15 loci influencing height in a Korean population , 2010, Journal of Human Genetics.
[76] Tanya M. Teslovich,et al. Association analyses of 249,796 individuals reveal 18 new loci associated with body mass index , 2010 .
[77] D. Clayton,et al. Genome-wide association study and meta-analysis finds over 40 loci affect risk of type 1 diabetes , 2009, Nature Genetics.
[78] G. Ginsburg,et al. Genome-Wide Association Study of Lp-PLA 2 Activity and Mass in the Framingham Heart Study , 2010 .
[79] Yurii S. Aulchenko,et al. ProbABEL package for genome-wide association analysis of imputed data , 2010, BMC Bioinformatics.
[80] K. Murthy,et al. Insulin-like growth factor-binding protein-5 stimulates growth of human intestinal muscle cells by activation of G{alpha}i3. , 2009, American journal of physiology. Gastrointestinal and liver physiology.
[81] X. Estivill,et al. Case-Control Study of Six Genes Asymmetrically Expressed in the Two Cerebral Hemispheres: Association of BAIAP2 with Attention-Deficit/Hyperactivity Disorder , 2009, Biological Psychiatry.
[82] K. Aston,et al. Genome-wide study of single-nucleotide polymorphisms associated with azoospermia and severe oligozoospermia. , 2009, Journal of andrology.
[83] W. Rottbauer,et al. Nexilin mutations destabilize cardiac Z-disks and lead to dilated cardiomyopathy , 2009, Nature Medicine.
[84] Christian Gieger,et al. A genome-wide meta-analysis identifies 22 loci associated with eight hematological parameters in the HaemGen consortium , 2009, Nature Genetics.
[85] K. Ng,et al. Is Wnt signalling the final common pathway leading to bone formation? , 2009, Molecular and Cellular Endocrinology.
[86] Christian Gieger,et al. Multiple loci influence erythrocyte phenotypes in the CHARGE Consortium , 2009, Nature Genetics.
[87] S. Bessa,et al. The role of glutathione S- transferase M1 and T1 gene polymorphisms and oxidative stress-related parameters in Egyptian patients with essential hypertension. , 2009, European journal of internal medicine.
[88] M. Daly,et al. Common body mass index-associated variants confer risk of extreme obesity. , 2009, Human molecular genetics.
[89] P. Visscher,et al. Common polygenic variation contributes to risk of schizophrenia and bipolar disorder , 2009, Nature.
[90] N. Wareham,et al. Association of variants in the PCSK1 gene with obesity in the EPIC-Norfolk study , 2009, Human molecular genetics.
[91] K. Siminovitch,et al. Primary biliary cirrhosis associated with HLA, IL12A, and IL12RB2 variants. , 2009, The New England journal of medicine.
[92] S. Lo,et al. Up-regulation of C-terminal tensin-like molecule promotes the tumorigenicity of colon cancer through beta-catenin. , 2009, Cancer research.
[93] Laura J. Scott,et al. Edinburgh Research Explorer Genome-wide association scan meta-analysis identifies three loci influencing adiposity and fat distribution , 2022 .
[94] S. Potkin,et al. Gene discovery through imaging genetics: identification of two novel genes associated with schizophrenia , 2009, Molecular Psychiatry.
[95] J. Tanti,et al. Involvement of TNF-α in abnormal adipocyte and muscle sortilin expression in obese mice and humans , 2009, Diabetologia.
[96] Alberto Piazza,et al. Genome-wide association of early-onset myocardial infarction with single nucleotide polymorphisms and copy number variants , 2009, Nature Genetics.
[97] Barbara Heude,et al. Genome-wide association study for early-onset and morbid adult obesity identifies three new risk loci in European populations , 2009, Nature Genetics.
[98] G. Abecasis,et al. Genotype imputation. , 2009, Annual review of genomics and human genetics.
[99] Christian Gieger,et al. Six new loci associated with body mass index highlight a neuronal influence on body weight regulation , 2009, Nature Genetics.
[100] Christian Gieger,et al. Loci influencing lipid levels and coronary heart disease risk in 16 European population cohorts , 2009, Nature Genetics.
[101] Jennie R. Lill,et al. The Double-Histone-Acetyltransferase Complex ATAC Is Essential for Mammalian Development , 2008, Molecular and Cellular Biology.
[102] M. Kutlu,et al. Adipose tissue 11-beta-Hydroxysteroid Dehydrogenase Type 1 and Hexose-6-Phosphate Dehydrogenase gene expressions are increased in patients with type 2 diabetes mellitus. , 2008, Diabetes research and clinical practice.
[103] Andrew D. Johnson,et al. SNAP: a web-based tool for identification and annotation of proxy SNPs using HapMap , 2008, Bioinform..
[104] C. Hoggart,et al. Genome-wide association analysis of metabolic traits in a birth cohort from a founder population , 2008, Nature Genetics.
[105] Yongtao Guan,et al. Practical Issues in Imputation-Based Association Mapping , 2008, PLoS genetics.
[106] T. Hansen,et al. Common nonsynonymous variants in PCSK1 confer risk of obesity , 2008, Nature Genetics.
[107] Judy H. Cho,et al. Genome-wide association defines more than 30 distinct susceptibility loci for Crohn's disease , 2008, Nature Genetics.
[108] Jun Li,et al. Susceptibility locus for clinical and subclinical coronary artery disease at chromosome 9p21 in the multi-ethnic ADVANCE study. , 2008, Human molecular genetics.
[109] S. Yim,et al. Impact of Glutathione S-Transferase M1 and T1 Gene Polymorphisms on the Smoking-Related Coronary Artery Disease , 2008, Journal of Korean medical science.
[110] Francesco Falciani,et al. Deletion of Hexose-6-phosphate Dehydrogenase Activates the Unfolded Protein Response Pathway and Induces Skeletal Myopathy* , 2008, Journal of Biological Chemistry.
[111] H. Stefánsson,et al. Genetics of gene expression and its effect on disease , 2008, Nature.
[112] D. Strachan,et al. LDL-cholesterol concentrations: a genome-wide association study , 2008, The Lancet.
[113] R. Collins,et al. Newly identified loci that influence lipid concentrations and risk of coronary artery disease , 2008, Nature Genetics.
[114] Dolores Corella,et al. Six new loci associated with blood low-density lipoprotein cholesterol, high-density lipoprotein cholesterol or triglycerides in humans , 2008, Nature Genetics.
[115] Mario Falchi,et al. Genome-wide Association Study Identifies Genes for Biomarkers of Cardiovascular Disease: Serum Urate and Dyslipidemia , 2022 .
[116] G.,et al. Acute Renal Failure in Elderly due to Goodpasture ’ s Syndrome , 2008 .
[117] Harald Grallert,et al. Genome Wide Association (GWA) Study for Early Onset Extreme Obesity Supports the Role of Fat Mass and Obesity Associated Gene (FTO) Variants , 2007, PloS one.
[118] D. Stephan,et al. A survey of genetic human cortical gene expression , 2007, Nature Genetics.
[119] K. Oniki,et al. Combined glutathione S-transferase T1 and M1 positive genotypes afford protection against type 2 diabetes in Japanese. , 2007, Pharmacogenomics.
[120] L. Liang,et al. A genome-wide association study of global gene expression , 2007, Nature Genetics.
[121] Sevim Karakaş,et al. Glutathione S‐transferase gene polymorphisms in Turkish patients with diabetes mellitus , 2007, Cell biochemistry and function.
[122] Manuel A. R. Ferreira,et al. PLINK: a tool set for whole-genome association and population-based linkage analyses. , 2007, American journal of human genetics.
[123] K. Huse,et al. Systematic Association Mapping Identifies NELL1 as a Novel IBD Disease Gene , 2007, PloS one.
[124] C. Gieger,et al. Genomewide association analysis of coronary artery disease. , 2007, The New England journal of medicine.
[125] Gonçalo R. Abecasis,et al. Genetic variants regulating ORMDL3 expression contribute to the risk of childhood asthma , 2007, Nature.
[126] P. Donnelly,et al. A new multipoint method for genome-wide association studies by imputation of genotypes , 2007, Nature Genetics.
[127] Yiping Chen,et al. Shox2 is required for chondrocyte proliferation and maturation in proximal limb skeleton. , 2007, Developmental biology.
[128] Meena Kumari,et al. Lifecourse influences on health among British adults: effects of region of residence in childhood and adulthood. , 2007, International journal of epidemiology.
[129] Yurii S. Aulchenko,et al. BIOINFORMATICS APPLICATIONS NOTE doi:10.1093/bioinformatics/btm108 Genetics and population analysis GenABEL: an R library for genome-wide association analysis , 2022 .
[130] Sonja W. Scholz,et al. Genome-wide genotyping in amyotrophic lateral sclerosis and neurologically normal controls: first stage analysis and public release of data , 2007, The Lancet Neurology.
[131] Eric Boerwinkle,et al. Population-based resequencing of ANGPTL4 uncovers variations that reduce triglycerides and increase HDL , 2007, Nature Genetics.
[132] M. Sigvardsson,et al. Critical Role for Ebf1 and Ebf2 in the Adipogenic Transcriptional Cascade , 2006, Molecular and Cellular Biology.
[133] Ioannis Panagopoulos,et al. Fusion of the tumor-suppressor gene CHEK2 and the gene for the regulatory subunit B of protein phosphatase 2 PPP2R2A in childhood teratoma. , 2006, Neoplasia.
[134] S. Mohan,et al. Serum Levels of Insulin-Like Growth Factor (IGF); IGF-Binding Proteins-3, -4, and -5; and Their Relationships to Bone Mineral Density and the Risk of Vertebral Fractures in Postmenopausal Women , 2006, Calcified Tissue International.
[135] Rudolf Grosschedl,et al. EBF2 regulates osteoblast-dependent differentiation of osteoclasts. , 2005, Developmental cell.
[136] D. Sabatini,et al. Redox Regulation of the Nutrient-sensitive Raptor-mTOR Pathway and Complex* , 2005, Journal of Biological Chemistry.
[137] G. Abecasis,et al. Handling marker-marker linkage disequilibrium: pedigree analysis with clustered markers. , 2005, American journal of human genetics.
[138] A. P. Morris,et al. Direct analysis of unphased SNP genotype data in population‐based association studies via Bayesian partition modelling of haplotypes , 2005, Genetic epidemiology.
[139] K. Kandror,et al. Sortilin is essential and sufficient for the formation of Glut4 storage vesicles in 3T3-L1 adipocytes. , 2005, Developmental cell.
[140] German Diabetes Association , 2005, Diabetologia.
[141] Jonathan C. Cohen,et al. Multiple Rare Alleles Contribute to Low Plasma Levels of HDL Cholesterol , 2004, Science.
[142] Jennifer R. Harris,et al. Heritability of Adult Body Height: A Comparative Study of Twin Cohorts in Eight Countries , 2003, Twin Research.
[143] D. Ray,et al. Mutations in the genes encoding 11β-hydroxysteroid dehydrogenase type 1 and hexose-6-phosphate dehydrogenase interact to cause cortisone reductase deficiency , 2003, Nature Genetics.
[144] S. Masetti,et al. Interactive effect of the glutathione S-transferase genes and cigarette smoking on occurrence and severity of coronary artery risk , 2003, Journal of Molecular Medicine.
[145] T. Clemens,et al. Paracrine Overexpression of IGFBP‐4 in Osteoblasts of Transgenic Mice Decreases Bone Turnover and Causes Global Growth Retardation , 2003, Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research.
[146] M. Katoh. GIPC gene family (Review). , 2002, International journal of molecular medicine.
[147] H. Kirikoshi,et al. Molecular cloning and characterization of human GIPC2, a novel gene homologous to human GIPC1 and Xenopus Kermit. , 2002, International journal of oncology.
[148] A. Astrup,et al. Obesity : Preventing and managing the global epidemic , 2000 .
[149] K. Yoshida,et al. The Occurrence of Three Isoforms of Heparan Sulfate 6-O-Sulfotransferase Having Different Specificities for Hexuronic Acid Adjacent to the TargetedN-Sulfoglucosamine* , 2000, The Journal of Biological Chemistry.
[150] A. Karlsson,et al. Identification of a novel human adenylate kinase. cDNA cloning, expression analysis, chromosome localization and characterization of the recombinant protein. , 1999, European journal of biochemistry.
[151] Nancy G Brinker,et al. The Susan G. Komen breast cancer foundation. , 1998, Breast disease.
[152] M. Neale,et al. Genetic and Environmental Factors in Relative Body Weight and Human Adiposity , 1997, Behavior genetics.
[153] Y. Matsuzawa,et al. Hepatocyte nuclear factor-4 alpha gene mutations in Japanese non-insulin dependent diabetes mellitus (NIDDM) patients. , 1996, Research communications in molecular pathology and pharmacology.
[154] Y. Benjamini,et al. Controlling the false discovery rate: a practical and powerful approach to multiple testing , 1995 .
[155] B. Lamberg. THE SIGNE AND ANE GYLLENBERG FOUNDATION , 1988, Acta dermato-venereologica. Supplementum.
[156] M. Binoux,et al. Serum levels of insulin-like growth factor (IGF) and IGF-binding protein in constitutionally short children and adolescents. , 1986, Acta endocrinologica.
[157] A. Stunkard,et al. A twin study of human obesity. , 1986, JAMA.